Identifiers and Description

Gene Model Identifier

TTHERM_00181100

Standard Name

PUS3 (PseudoUridine Synthase 3)

Aliases

PreTt29828 | 14.m00395 | DEG1

Description

PUS3 tRNA pseudouridine synthase; tRNA pseudouridine synthase A family protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• pseudouridine synthase activity (IEA) | GO:0009982
• RNA binding (IEA) | GO:0003723

Biological Process

• RNA modification (IEA) | GO:0009451
• pseudouridine synthesis (IEA) | GO:0001522

Domains

• ( PF01416 ) tRNA pseudouridine synthase
• ( TIGR00071 ) tRNA pseudouridine synthase A

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.5%

TetraMine Data

TTHERM_00181100

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_09939.1	9.997093137033517e-262	tRNA pseudouridine synthase A family protein (498 aa)
DictyBase	DDB_G0288909	2.998830401637127e-79	pus3 on chromosome: 5 position 2110038 to 2111898
WormBase	WBGene00006473	7.002037867398653e-67	locus:tag-124 Probable tRNA pseudouridine synthase tag-124 status:Confirmed UniProt: Q09524 protein_id:CAA87378.1
SGD	YFL001W	6.997942222381785e-66	DEG1 tRNA:pseudouridine syntha se, introduces pseudouridines at position 38 or 39 in tRNA, important for maintenance of t ranslation efficiency and norm al cell growth, localizes to b oth the nucleus and cytoplasm; non-essential for viability
Oxytricha	Contig18928.0.g26	1.9997677415930956e-65	tRNA pseudouridine synthase
Stentor Coeruleus	SteCoe_32353	1.603810890548638e-28

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00181100(coding)
ATGGATACAATTTAATAAAGCGAATAAGGAAATATACAAATATCTTAAGAAGGCCAAAGT
GAATAGAAAGCTAACTAAGATATTAAAAAAGATGAAGAGCAAAAAAGCGAGTCATTAGAA
AGTGAAGACTTAGATAAATTTTCTAAGGAAGAAATCATTAAAAAATATTTGTTCATAAAA
AAGGAAAATTAAGTTTTAAGAAAATAATTAAACCATAACAACGACACAAAAGCCCCTATT
CCTAATAATAGCTCTTAAAATGAGACTAAAAAGTAAAAGAAAGAGCAAAAATAGAATAAC
AAAAAGGAAAGCCTATTCGAAATCTACCAATAACAGCATTATGCCTTAAAAATGTCTTAT
GTTGGAATCAATTATCAAGGCTTAGCATATTAGTAAGAAACTGACAACACTGTAGAAGAA
TAGCTCTTCAAGGCACTTGAAAAGACAACACTGATAAAAAATAGAGATAATTGCAATTTC
ACACGTTCAGGAAGAACTGACAAAGGAGTTAGTGCTTTAGGATAAGTTATTGGTATCACT
CTTAGAACTTCAATAAAAATAGGTGAAAATATTGATGAAATAGAAAATAAATTAGATTAC
ATTAAGATGCTTAATAGTAATCTTCCAGACGACATAAGGATTTTAGGTTGTTCTAAAGTT
GATCCTGCTTTTAATGCAAGATTTGATTGTTAAAAGAGAATTTATAAGTATTACTTTTTT
GAGAATTAGATGGATATTTAAAGAATGAAGGAAGCAGCTAACCTCTTTTTGGGAGAACAC
GATTTTAGAAATTTCTGCAAAATAGATGTTTTGCAAACACTTAACTATGTTAGAATTATT
TATTAACTTGATATAGAAGAAGTTTAGGCTAATTTTGGTACTCTTGACCCTCGTTCTAAA
TTATATGTAGCAACTATTCAAGGAAGTGCTTTCCTTTGGCATTAAATCAGAAACATGATG
GCTATACTTTTTCTAGTAGGCAGAAAATAAGAAGAACCTTCAATAGTTACAGAGCTTCTT
GATATTTAAAAGAATCCATCTAAACCTAATTATGAGATGGCTCCTGATTATCCTCTAGTA
TTATTTGATTGCTTGTACAATAATGTTAGTTTTAACTACAGTAGCGATTAGATAAAGATT
TATGAACATTATTTGCAGATAATCTAAAAAAAGTGTATCGAAAATTAGCTTTATATTACA
ACTCTCAATTATATGGCATAAACTGCTTAGCAATTTAACAATTATAATCTTATTTAAAAT
TCATTGATTTCAGAAGAAGCTACTCTTCGTAATAAGAAATACTAGCATCTTTCAAAAAGA
TAATGTGCTTAATCATCAGAAGACACTTTAAAAAATTTAAAAGGCAGAAAATTAGATAAG
TTTTTAATTAAGCAAGAAAAATAGATAAATTATTAATAGTAGCGCGAAGCAGAAAAGAAT
TTATCATAAACATAAGATTAAACCTCTGAAGGAAACGATACTTAAGAATGA

>TTHERM_00181100(protein)
MDTIQQSEQGNIQISQEGQSEQKANQDIKKDEEQKSESLESEDLDKFSKEEIIKKYLFIK
KENQVLRKQLNHNNDTKAPIPNNSSQNETKKQKKEQKQNNKKESLFEIYQQQHYALKMSY
VGINYQGLAYQQETDNTVEEQLFKALEKTTLIKNRDNCNFTRSGRTDKGVSALGQVIGIT
LRTSIKIGENIDEIENKLDYIKMLNSNLPDDIRILGCSKVDPAFNARFDCQKRIYKYYFF
ENQMDIQRMKEAANLFLGEHDFRNFCKIDVLQTLNYVRIIYQLDIEEVQANFGTLDPRSK
LYVATIQGSAFLWHQIRNMMAILFLVGRKQEEPSIVTELLDIQKNPSKPNYEMAPDYPLV
LFDCLYNNVSFNYSSDQIKIYEHYLQIIQKKCIENQLYITTLNYMAQTAQQFNNYNLIQN
SLISEEATLRNKKYQHLSKRQCAQSSEDTLKNLKGRKLDKFLIKQEKQINYQQQREAEKN
LSQTQDQTSEGNDTQE

>TTHERM_00181100(gene)
ATGGATACAATTTAATAAAGCGAATAAGGAAATATACAAATATCTTAAGAAGGCCAAAGT
GAATAGAAAGCTAACTAAGATATTAAAAAAGATGAAGAGCAAAAAAGCGAGTCATTAGAA
AGTGAAGACTTAGATAAATTTTCTAAGGAAGAAATCATTAAAAAATATTTGTTCATAAAA
AAGGAAAATTAAGTTTTAAGAAAATAATTAAACCATAACAACGACACAAAAGCCCCTATT
CCTAATAATAGCTCTTAAAATGAGACTAAAAAGTAAAAGAAAGAGCAAAAATAGAATAAC
AAAAAGGAAAGCCTATTCGAAATCTACCAATAACAGCATTATGCCTTAAAAATGTCTTAT
GTTGGAATCAATTATCAAGGCTTAGCATATTAGTAAGAAACTGACAACACTGTAGAAGAA
TAGCTCTTCAAGGCACTTGAAAAGACAACACTGATAAAAAATAGAGATAATTGCAATTTC
ACACGTTCAGGAAGAACTGACAAAGGAGTTAGTGCTTTAGGATAAGTTATTGGTATCACT
CTTAGAACTTCAATAAAAATAGGTGAAAATATTGATGAAATAGGTAATATTAATTAAGTT
AGTCTATATTATATATAAATATTTATTTATTATTTACTTTGATAGAAATAACAATTTTAA
AATATTTATTTTTTACAATGTGATAGAAAATAAATTAGATTACATTAAGATGCTTAATAG
TAATCTTCCAGACGACATAAGGATTTTAGGTTGTTCTAAAGTTGATCCTGCTTTTAATGC
AAGATTTGATTGTTAAAAGAGAATTTATAAGTATTACTTTTTTGAGAATTAGATGGATAT
TTAAAGAATGAAGGAAGCAGCTAACCTCTTTTTGGGAGAACACGATTTTAGAAATTTCTG
CAAAATAGATGTTTTGCAAACACTTAACTATGTTAGAATTATTTATTAACTTGATATAGA
AGAAGTTTAGGCTAATTTTGGTACTCTTGACCCTCGTTCTAAATTATATGTAGCAACTAT
TCAAGGAAGTGCTTTCCTTTGGCATTAAATCAGAAACATGATGGCTATACTTTTTCTAGT
AGGCAGAAAGTAATTATTTAGTTAGAAATTTAGTTTAAATACTTTATGAGTAATATTTAT
TATTTTAGATAAGAAGAACCTTCAATAGTTACAGAGCTTCTTGATATTTAAAAGAATCCA
TCTAAACCTAATTATGAGATGGCTCCTGATTATCCTCTAGTATTATTTGATTGCTTGTAC
AATAATGTTAGTTTTAACTACAGTAGCGATTAGATAAAGATTTATGAACATTATTTGCAG
ATAATCTAAAAAAAGTGTATCGAAAATTAGCTTTATATTACAACTCTCAATTATATGGCA
TAAACTGCTTAGCAATTTAACAATTATAATCTTATTTAAAATTCATTGATTTCAGAAGAA
GCTACTCTTCGTAATAAGAAATACTAGCATCTTTCAAAAAGATAATGTGCTTAATCATCA
GAAGACACTTTAAAAAATTTAAAAGGCAGAAAATTAGATAAGTTTTTAATTAAGCAAGAA
AAATAGATAAATTATTAATAGTAGCGCGAAGCAGAAAAGAATTTATCATAAACATAAGAT
TAAACCTCTGAAGGAAACGATACTTAAGAATGA