Identifiers and Description

Gene Model Identifier

TTHERM_00011450

Standard Name

PUS1 (PseudoUridine Synthase 1)

Aliases

PreTt11751 | 1.m00799

Description

tRNA pseudouridine synthase family protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• RNA binding (IEA) | GO:0003723
• pseudouridine synthase activity (IEA) | GO:0009982

Biological Process

• RNA modification (IEA) | GO:0009451
• pseudouridine synthesis (IEA) | GO:0001522

Domains

• ( PF06519 ) TolA protein
• ( PF01416 ) tRNA pseudouridine synthase
• ( TIGR00071 ) tRNA pseudouridine synthase A

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 16.7%

TetraMine Data

TTHERM_00011450

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_02803.1	9.997093137033517e-262	tRNA pseudouridine synthase (4 71 aa)
WormBase	WBGene00004248	1.0002124404074584e-26	locus:pus-1 tRNA pseudouridi ne synthase status:Confirmed UniProt:Q9XXN0 protein_id :CAA16518.1
Oxytricha	Contig20508.0.g59	2.99851380290819e-19	tRNA pseudouridine synthase
DictyBase	DDB_G0290987	2.999758165421992e-18	pus1 on chromosome: 5 position 4857087 to 4859177
Stentor Coeruleus	SteCoe_25308	8.533047625744066e-17
SGD	YPL212C	0.000000000000020000882446601127	PUS1 tRNA:pseudouridine syntha se, introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA; nuclear prote in that appears to be involved in tRNA export; also acts on U2 snRNA

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00011450(coding)
ATGATTTAAACTAAAAGAAATTTCTTTAAGATCAAAGTAGCAATATTCTTTGGCTATAAT
GGCAAAGGGTACCATGGTTCATAGAGCTAAAAGGACTAAAACATTAAGACTATAGAAAAG
TCATTGTTTGAAGGTTTGATAGACTCTAAATTGATTAGTGAAACACATATGGGAGAGTTA
AAAAAAGCAGGTTGGGGAAGAGGAGCTAGAACTGATAAGGGAGTTCATGCATTATGTAAT
GGCGTTAACGTTAAGTTGGCTATTAGTGAAGAGTACCTTATGAGAGGTAGTCCTCTTAGA
ATGGATGATAAAAATCCTGAAGAAATTTAAAAGGAAATATAAGAAAAAAACGAAATATTA
TTAGAATCTGAACAATATAAAAAACCAGAAGAAAACTCTGGTGAATAATAAAATGCAAAT
GGTAATTAAGCATCTGAAAAAGAAATAAAATCCTAGGCTATAGAAGAAGAAGCTGCTGAT
AATGATTAAGAAATAGCAGAAGAATAGGAAGAATAAAAGGAAGGAGAAAAAAATTTAGAA
GAAAGTAAGAAGGTTGAAGATATGACTGAAGAAGAGAGATAAGAAAGAAGTAGAAGATTA
CAATAAGAGGCTGAAGAAAACAGAAAAAAGAAGGAAGTTAGTAAGGCTCATCACAAATAA
CTGTAAGAATTTGCTAACGAAAGAAGAAAGCATATCGATATAGATAAGATTATAAATGCA
TTAAACAGCAATTTACCAGCAGATATTCGCTGTGTTTCAATTAAACAGGTATCTCGTAAA
TTTGATATTCGTACTCACTGCAAATACAGAGTATACGAATACTTAATGCCTCTTTTTATG
TATCAGAAGTATGATGACATTATAGCAGGTACTCCTATGACAGAAGAATTTGAGTAAAAA
ACCATGTAAAGAGTTTCTACATTAGCTGATAAGTTCAAAGGAACTCATAATTACCACAAT
TACACAAGATAAATGAAAGCAAAAGACCCTCGTTGTATGCGTTATATTTTAGACATGAAA
ACTGAATTAATCACCAACCCTTAAAACGGAATGAAATTCATTAGATTTACTTTAGTAGGA
TAGAGTTTTGTTTATCATTAAATTCGTAAGATGATGGGTATGATTTGCATGATGATTTAG
GAAGACTACCCTGACAACTTTATGGATTCTAGCTTTTTCCATAATGTCATGCGTATTTGG
CTTGCTCCTGCCCATGGTTTATTCCTAAATCGTATGAGATTTGATAGTTACAACAAGAAA
CCTGAAATCCCAGAACCTATTGAATTCGATAAGATTGAAGAAGATCGTTTAAGAGAAATG
AGAGATATTATTGAAAAAGCAGTCATGAACGAAGAGGATGTTAATGCAATTTACAAATAA
TGGATTAAAGATGTCAAAGCAGGAAACGAGCTTGCTGAAGAAAATGAATCTGTTTCAGGA
GATATGGATCAATGA

>TTHERM_00011450(protein)
MIQTKRNFFKIKVAIFFGYNGKGYHGSQSQKDQNIKTIEKSLFEGLIDSKLISETHMGEL
KKAGWGRGARTDKGVHALCNGVNVKLAISEEYLMRGSPLRMDDKNPEEIQKEIQEKNEIL
LESEQYKKPEENSGEQQNANGNQASEKEIKSQAIEEEAADNDQEIAEEQEEQKEGEKNLE
ESKKVEDMTEEERQERSRRLQQEAEENRKKKEVSKAHHKQLQEFANERRKHIDIDKIINA
LNSNLPADIRCVSIKQVSRKFDIRTHCKYRVYEYLMPLFMYQKYDDIIAGTPMTEEFEQK
TMQRVSTLADKFKGTHNYHNYTRQMKAKDPRCMRYILDMKTELITNPQNGMKFIRFTLVG
QSFVYHQIRKMMGMICMMIQEDYPDNFMDSSFFHNVMRIWLAPAHGLFLNRMRFDSYNKK
PEIPEPIEFDKIEEDRLREMRDIIEKAVMNEEDVNAIYKQWIKDVKAGNELAEENESVSG
DMDQ

>TTHERM_00011450(gene)
ATGATTTAAACTAAAAGAAATTTCTTTAAGATCAAAGTAGCAATATTCTTTGGCTATAAT
GGCAAAGGGTACCATGGTTCATAGAGCTAAAAGGACTAAAACATTAAGACTATAGAAAAG
TCATTGTTTGAAGGTTTGATAGACTCTAAATTGATTAGTGAAACACATATGGGAGAGTTA
AAAAAAGCAGGTTGGGGAAGAGGAGCTAGAACTGATAAGGGAGTTCATGCATTATGTAAT
GGCGTTAACGTTAAGTTGGCTATTAGTGAAGAGTACCTTATGAGAGGTAGTCCTCTTAGA
ATGGATGATAAAAATCCTGAAGAAATTTAAAAGGAAATATAAGAAAAAAACGAAATATTA
TTAGAATCTGAACAATATAAAAAACCAGAAGAAAACTCTGGTGAATAATAAAATGCAAAT
GGTAATTAAGCATCTGAAAAAGAAATAAAATCCTAGGCTATAGAAGAAGAAGCTGCTGAT
AATGATTAAGAAATAGCAGAAGAATAGGAAGAATAAAAGGAAGGAGAAAAAAATTTAGAA
GAAAGTAAGAAGGTTGAAGATATGACTGAAGAAGAGAGATAAGAAAGAAGTAGAAGATTA
CAATAAGAGGCTGAAGAAAACAGAAAAAAGAAGGAAGTTAGTAAGGCTCATCACAAATAA
CTGTAAGAATTTGCTAACGAAAGAAGAAAGCATATCGATATAGATAAGATTATAAATGCA
TTAAACAGCAATTTACCAGCAGATATTCGCTGTGTTTCAATTAAACAGGTATCTCGTAAA
TTTGATATTCGTACTCACTGCAAATACAGAGTATACGAATACTTAATGCCTCTTTTTATG
TATCAGAAGTATGATGACATTATAGCAGGTACTCCTATGACAGAAGAATTTGAGTAAAAA
ACCATGTAAAGAGTTTCTACATTAGCTGATAAGTTCAAAGGAACTCATAATTACCACAAT
TACACAAGATAAATGAAAGCAAAAGACCCTCGTTGTATGCGTTATATTTTAGACATGAAA
ACTGAATTAATCACCAACCCTTAAAACGGAATGAAATTCATTAGATTTACTTTAGTAGGA
TAGAGTTTTGTTTATCATTAAATTCGTAAGATGATGGGTATGATTTGCATGATGATTTAG
GAAGACTACCCTGACAACTTTATGGATTCTAGCTTTTTCCATAATGTCATGCGTATTTGG
CTTGCTCCTGCCCATGGTTTATTCCTAAATCGTATGAGATTTGATAGTTACAACAAGAAA
CCTGAAATCCCAGAACCTATTGAATTCGATAAGATTGAAGAAGATCGTTTAAGAGAAATG
AGAGATATTATTGAAAAAGCAGTCATGAACGAAGAGGATGTTAATGCAATTTACAAATAA
TGGATTAAAGATGTCAAAGCAGGAAACGAGCTTGCTGAAGAAAATGAATCTGTTTCAGGA
GATATGGATCAATGA