Identifiers and Description

Gene Model Identifier

TTHERM_00614820

Standard Name

POL12 (DNA polymerase alpha subunit B)

Aliases

PreTt19130 | 85.m00123 | 3725.m00016

Description

Homolog of Saccharomyces POL12, B subunit of DNA polymerase alpha-primase complex.

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• DNA binding (IEA) | GO:0003677
• DNA-directed DNA polymerase activity (IEA) | GO:0003887

Biological Process

• DNA replication (IEA) | GO:0006260

Domains

• ( PF04042 ) DNA polymerase epsilon subunit B

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.9%

TetraMine Data

TTHERM_00614820

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_18325.1	9.997093137033517e-262	hypothetical protein (597 aa)
Oxytricha	Contig11781.0.0.g16	0.00000000000004998767099442072	DNA polymerase alpha/epsilon s ubunit B
SGD	YBL035C	0.00000000000006002591555650462	POL12 B subunit of DNA polymer ase alpha-primase complex, req uired for initiation of DNA re plication during mitotic and p remeiotic DNA synthesis; also functions in telomere capping and length regulation
DictyBase	DDB_G0282731	0.00000000000040012475857291343	polA2 on chromosome: 3 positio n 6220731 to 6222999
WormBase	WBGene00001002	0.0000000000008001317446409227	locus:div-1 DNA polymerase a lpha subunit B status:Partia lly_confirmed UniProt:Q21625 protein_id:CAA83467.2

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00614820(coding)
ATGGAAGAATTTGAAAAAATATTAGAAGAAATTGATTCTGCTAATTTAAGCCAAAATGCA
GTTTAATAATTGAAATAGTTAATTATTAGCAATGGAATATTAGATGATGAGTAATTAATG
GAAAAGTGGCTCTTTTAATTGGAGGCAATCATTTACAATAGCAAGTAAAAGTTTCTTGAA
GCTTAACTGATGGATTTTAAGAAGAATGTGCTTAATTAGGACATCAAAAAACCTCAAAAT
GACAATTTTAAAAAAATAAAGGAATCTGAAGTTTAAAAAAATATAGACATTATTAAAGGT
GATGCAGATTTATTTACTAAAGCTTCTTCAGCCAAAAAACAGACATCTACTTAATAAGCA
AATAATGCAGCAATTGATTGCGAAGAATAATTGCGTTAGTAGTTAGGAAAGGAATCAATG
CTAGACCCAAAACGTTTTTCATATAATAGTAACCTTCCCTAGGTAAACTTCGAAAAAAAT
TAGCATTAGAATTCCAACAATATGACTATTGTCGATTTATTTGAATAATACGATCCTAAT
AAAATTCCTAACTACTTAACAAATAATATTGATAAAATTCGCAAACATCTCGAATAAAGG
ATCCTAACTTTCAAAATACAAAATTACAGTTAATTTATAGTTAACGGTGAATAGTTAATA
AATGATGTCAGCTCTTACTCTAAGACAGAAGAAGTAAAAATGGTTGGCAGATTGATATCG
ACAGAAAATGGTTTTTTGAATACAACAAATTTAAGGATAGAACTTAATAGAAATCAATAT
TTCGATCTCGTCTTTGAAAACGATTTTGATTTTGGTAACAATGTTCTTTTTCCTAATTAG
ATAGTGATGGTTAAAGGTATCATAAATGAAAAAGAAGAATTAGTAGTAAGTGAGTTAATC
ACAGATCACATTAAGGAAATAACTGATGAAGAACATCCAAAAATTGATAATTTGAACTAA
GATGAAAGTTAGCTTATCATGGTAGCTGCAGGTCCTTTTTCTACTGTTATGTCTACTTAA
TATACATCATTTGATAACATTCTTCATGTTGCAAAGACTAAGAAAGTAAGCACTCTTATC
CTTCTTGGACCATTTTTAGATATAAAGAATGAAATTTTAAAAGATGGCAGTATTATAATA
AATAGCAAAGAATATACTTTTGAGTAATTGTAAAATTCCTTGTTTGAAAAAGCTGTAAAG
GAATTAGAAGGAAAAACTTAAATAATCATTGTCCCTTCTACTCGCGATATTCTTTCCACT
GACTCTATTCCTTAAATGAGTCTTGAAATTAAAGTTTCTGAACATAAGAATTCTATTCAC
TCTTACTCTAATCCAGCTTATATTGATATTGATAAATTAAGAGTTTACATTGCTAACTCA
GATGTCGGTATGATCACTCTTTAAAATAGTTTGTTAGATAAAAAGATTCCCTACATGCAG
CAATCACGTCTTACTTTTAAAGCACTTATGAATTAATAAAATTTGTACTCCATATATCCT
ATGAGAAATCCACAAGATTCATAATAAATATTAGAAACTGTAAAACTTCCTAATATAAAT
GATTTTGACATCCCTTTTGACTACTAGCTAGAATAATATCCTCATATAATTATCTCTCCT
TCATCTCTACCAAAATTTGCAACTAAAATCTATAATACCGTCGTCATAAATCCTAATTAT
GTTATACGTGATGGCTCATAAGCAGGAAATTTTGCTATAATTACTTTATTCAAAGATTCT
GACATTCCTATTCACGAAAGAACTCGTGTAGATTTATATTGTTTGTGA

>TTHERM_00614820(protein)
MEEFEKILEEIDSANLSQNAVQQLKQLIISNGILDDEQLMEKWLFQLEAIIYNSKQKFLE
AQLMDFKKNVLNQDIKKPQNDNFKKIKESEVQKNIDIIKGDADLFTKASSAKKQTSTQQA
NNAAIDCEEQLRQQLGKESMLDPKRFSYNSNLPQVNFEKNQHQNSNNMTIVDLFEQYDPN
KIPNYLTNNIDKIRKHLEQRILTFKIQNYSQFIVNGEQLINDVSSYSKTEEVKMVGRLIS
TENGFLNTTNLRIELNRNQYFDLVFENDFDFGNNVLFPNQIVMVKGIINEKEELVVSELI
TDHIKEITDEEHPKIDNLNQDESQLIMVAAGPFSTVMSTQYTSFDNILHVAKTKKVSTLI
LLGPFLDIKNEILKDGSIIINSKEYTFEQLQNSLFEKAVKELEGKTQIIIVPSTRDILST
DSIPQMSLEIKVSEHKNSIHSYSNPAYIDIDKLRVYIANSDVGMITLQNSLLDKKIPYMQ
QSRLTFKALMNQQNLYSIYPMRNPQDSQQILETVKLPNINDFDIPFDYQLEQYPHIIISP
SSLPKFATKIYNTVVINPNYVIRDGSQAGNFAIITLFKDSDIPIHERTRVDLYCL

>TTHERM_00614820(gene)
ATGGAAGAATTTGAAAAAATATTAGAAGAAATTGATTCTGCTAATTTAAGCCAAAATGCA
GTTTAATAATTGAAATAGTTAATTATTAGCAATGGAATATTAGATGATGAGTAATTAATG
GAAAAGTGGCTCTTTTAATTGGAGGCAATCATTTACAATAGCAAGTAAAAGTTTCTTGAA
GCTTAACTGATGGATTTTAAGAAGAATGTGCTTAATTAGGACATCAAAAAACCTCAAAAT
GACAATTTTAAAAAAATAAAGGAATCTGAAGTTTAAAAAAATATAGACATTATTAAAGGT
GATGCAGATTTATTTACTAAAGCTTCTTCAGCCAAAAAACAGACATCTACTTAATAAGCA
AATAATGCAGCAATTGATTGCGAAGAATAATTGCGTTAGTAGTTAGGAAAGGAATCAATG
CTAGACCCAAAACGTTTTTCATATAATAGTAACCTTCCCTAGGTAAACTTCGAAAAAAAT
TAGCATTAGAATTCCAACAATATGACTATTGTCGATTTATTTGAATAATACGATCCTAAT
AAAATTCCTAACTACTTAACAAATAATATTGATAAAATTCGCAAACATCTCGAATAAAGG
ATCCTAACTTTCAAAATACAAAATTACAGTTAATTTATAGTTAACGGTGAATAGTTAATA
AATGATGTCAGCTCTTACTCTAAGACAGAAGAAGTAAAAATGGTTGGCAGATTGATATCG
ACAGAAAATGGTTTTTTGAATACAACAAATTTAAGGATAGAACTTAATAGAAATCAATAT
TTCGATCTCGTCTTTGAAAACGATTTTGATTTTGGTAACAATGTTCTTTTTCCTAATTAG
ATAGTGATGGTTAAAGGTATCATAAATGAAAAAGAAGAATTAGTAGTAAGTGAGTTAATC
ACAGATCACATTAAGGAAATAACTGATGAAGAACATCCAAAAATTGATAATTTGAACTAA
GATGAAAGTTAGCTTATCATGGTAGCTGCAGGTCCTTTTTCTACTGTTATGTCTACTTAA
TATACATCATTTGATAACATTCTTCATGTTGCAAAGACTAAGAAAGTAAGCACTCTTATC
CTTCTTGGACCATTTTTAGATATAAAGAATGAAATTTTAAAAGATGGCAGTATTATAATA
AATAGCAAAGAATATACTTTTGAGTAATTGTAAAATTCCTTGTTTGAAAAAGCTGTAAAG
GAATTAGAAGGAAAAACTTAAATAATCATTGTCCCTTCTACTCGCGATATTCTTTCCACT
GACTCTATTCCTTAAATGAGTCTTGAAATTAAAGTTTCTGAACATAAGAATTCTATTCAC
TCTTACTCTAATCCAGCTTATATTGATATTGATAAATTAAGAGTTTACATTGCTAACTCA
GATGTCGGTATGATCACTCTTTAAAATAGTTTGTTAGATAAAAAGATTCCCTACATGCAG
CAATCACGTCTTACTTTTAAAGCACTTATGAATTAATAAAATTTGTACTCCATATATCCT
ATGAGAAATCCACAAGATTCATAATAAATATTAGAAACTGTAAAACTTCCTAATATAAAT
GATTTTGACATCCCTTTTGACTACTAGCTAGAATAATATCCTCATATAATTATCTCTCCT
TCATCTCTACCAAAATTTGCAACTAAAATCTATAATACCGTCGTCATAAATCCTAATTAT
GTTATACGTGATGGCTCATAAGCAGGAAATTTTGCTATAATTACTTTATTCAAAGATTCT
GACATTCCTATTCACGAAAGAACTCGTGTAGATTTATATTGTTTGTGA