Identifiers and Description

Gene Model Identifier

TTHERM_00929450

Standard Name

PGK1 (PhosphoGlycerate Kinase )

Aliases

PreTt17357 | 167.m00106 | PGK | 3752.m00301

Description

Phosphoglycerate kinase; glycolytic enzyme that catalyzes the conversion of 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• phosphoglycerate kinase activity (IEA) | GO:0004618

Biological Process

• glycolytic process (IEA) | GO:0006096

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.2%

TetraMine Data

TTHERM_00929450

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_19964.1	9.997093137033517e-262	phosphoglycerate kinase (421 a a)
Oxytricha	Contig392.1.g73	9.997093137033517e-262	Phosphoglycerate kinase
WormBase	WBGene00020185	1.999658401959794e-176	locus:pgk-1 Probable phospho glycerate kinase status:Conf irmed UniProt:P91427 prote in_id:CCD67788.1
SGD	YCR012W	4.0000050475224054e-168	PGK1 3-phosphoglycerate kinase , catalyzes transfer of high-e nergy phosphoryl groups from t he acyl phosphate of 1,3-bisph osphoglycerate to ADP to produ ce ATP; key enzyme in glycolys is and gluconeogenesis
DictyBase	DDB_G0287595	2.0009356157506544e-160	pgkA on chromosome: 5 position 494968 to 496392
Stentor Coeruleus	SteCoe_12639	2.001470128041443e-75

General Information

No Data fetched for General Information

Associated Literature

1. Ref:8052610: Golding GB, Tsao N, Pearlman RE (1994) Evidence for intron capture: an unusual path for the evolution of proteins. Proceedings of the National Academy of Sciences of the United States of America 91(16):7506-9
2. Ref:7922679: Golding B (1994) Exploratory analysis of multiple sequence alignments using phylogenies. Computer applications in the biosciences : CABIOS 10(3):243-7
3. Ref:1602492: Vohra GB, Golding GB, Tsao N, Pearlman RE (1992) A phylogenetic analysis based on the gene encoding phosphoglycerate kinase. Journal of molecular evolution 34(5):383-95

Sequences

>TTHERM_00929450(coding)
ATGTTGTCTCGTAAGATTGGTATTGATCACATCTTGAAACATATTGAAAACAAGAGAGTT
TTAATGAGAGTAGACTTCAACGTTCCTTTGAAGGAAGGTAAGGTTAAAGATCCTACTCGT
ATCTAAGGTTCTGTTCCTTCTATCAAGAAAATCTTAGAGTAAAATCCTAAAGGTCTTGTC
TTGATGAGTCACTTGGGTCGTCCTGATGGCAACAGAGTTGAAAAGCACTCAATGAAGCCT
GTTGTTCCTAAGCTTGAAGAATTACTCGGCACCAAGGTAACCTTCTTGAATGACTGTGTT
GGTAAGGATGTAGAAGAAGCTGTTAAATCAAGCAGAAACGGTGAAATCATTTTACTTGAA
AACTTGCGTTTCCATCCTGAAGAAGAAGGAAAGTACATCGATGCTGCAGGAAACAAGGTT
AAGGCTGACTCTAAGGCAGTTAAGGAATTCAGAAAATCTTTGACTAGTTTGGGTGACTTA
TTCGTCAACGATGCTTTCGGTACCGCTCACAGAGCTCACTCTTCCATGGTCGGTGTTGAT
CACAAAATCAGAGCTGCTGGTTACCTCTTGAAGAGAGAATTAGACTACTTCAGTAAGGCT
TTGGAATCCCCTAACAGACCTTTCTTAGTTGTCTTAGGTGGTGCTAAGGTCAAGGATAAA
ATCTAATTGATTGAAAGTATGCTTGACAAGGTCGATGAAATGATCATTGGTGGTGGTATG
GCCTTCACTTTCTTGAAGAAAATCCACAATATTGAAATTGGTAACTCCCTCTTCGACGAA
GAAGGTTATAAGATTGTTGACCAATTGTTAGAAAAGGCTAAAGCTAAGAATGTCAAGATC
CATTTACCAGTTGATTTCTTGTGCGGTGACTCACTTGAAGCCAACGCTAACACCCGTAGC
TTTGACTTAAAGAGTGGTATCCCTGCTGGATGGATTGGTTTAGATGCTGGTCCTAAGACT
ATGGCTGAAAACGCTGAAGCTGTTGCCCGTGCTAACACTATTGTCTGGAATGGTCCTTAA
GGTAGATTCGAAGTTGATAAGTTTAAAGTAGGATCTTCTGACCTTCTCAAGCACGTTGCT
ACTAGAACTTCCTAAGGAGCTACTTCTATTATTGGTGGTGGTGACACTGTCAATCTTGTT
CAACAAGAAAAGGCAACTCAAAAAGTCAGCCACGTCTCTACTGGTGGTGGTGCATCTCTT
GAACTTCTTGAAGGTAAAGTCCTTCCTGGTGTTGCTTATCTTACTGATATTGACTAACTT
TGA

>TTHERM_00929450(protein)
MLSRKIGIDHILKHIENKRVLMRVDFNVPLKEGKVKDPTRIQGSVPSIKKILEQNPKGLV
LMSHLGRPDGNRVEKHSMKPVVPKLEELLGTKVTFLNDCVGKDVEEAVKSSRNGEIILLE
NLRFHPEEEGKYIDAAGNKVKADSKAVKEFRKSLTSLGDLFVNDAFGTAHRAHSSMVGVD
HKIRAAGYLLKRELDYFSKALESPNRPFLVVLGGAKVKDKIQLIESMLDKVDEMIIGGGM
AFTFLKKIHNIEIGNSLFDEEGYKIVDQLLEKAKAKNVKIHLPVDFLCGDSLEANANTRS
FDLKSGIPAGWIGLDAGPKTMAENAEAVARANTIVWNGPQGRFEVDKFKVGSSDLLKHVA
TRTSQGATSIIGGGDTVNLVQQEKATQKVSHVSTGGGASLELLEGKVLPGVAYLTDIDQL

>TTHERM_00929450(gene)
ATGTTGTCTCGTAAGATTGGTATTGATCACATCTTGAAACATATTGAAAACAAGAGAGTT
TTAATGAGAGTAGACTTCAACGTTCCTTTGAAGGAAGGTAAGGTTAAAGATCCTACTCGT
ATCTAAGGTTCTGTTCCTTCTATCAAGAAAATCTTAGAGTAAAATCCTAAAGGTCTTGTC
TTGATGAGTCACTTGGGTCGTCCTGATGGCAACAGAGTTGAAAAGCACTCAATGAAGCCT
GTTGTTCCTAAGCTTGAAGAATTACTCGGCACCAAGGTATTTTATTTGGCATACTACATT
CTGATTTTTTTATCGTTATTTTTTCAAAAACTTATAGGTAACCTTCTTGAATGACTGTGT
TGGTAAGGATGTAGAAGAAGCTGTTAAATCAAGCAGAAACGGTGAAATCATTTTACTTGA
AAACTTGCGTTTCCATCCTGAAGAAGAAGGAAAGTACATCGATGCTGCAGGAAACAAGGT
ATTTTTTAATAACTTTATTTAGTTGACTAAGATCAAACCAAGTTTCTTTTCACTTATGGG
CCATATTTTATTAAGCCTATGAAAATCAATAGTTTGATTGAGAGTTTTGAATTTTTAAAA
ATTATGGTCCTAAACAACACCATTCTTTAACGGAGCTGAGTTATTTTAAAAGTTTAGCCA
CCAAGCATTAAGTTGGTGTGCTTTTCAAAAAATTTCTATAATATACCAAGAAGTATTCTT
CAAATTCAATTACTATTTTTTTTGCCATTTTTAAAGGTTAGTTTTTGATTTTTTAAAAAA
AAAAGATCATAAATTAATCAATAAATAAATAACAAGAAGGTAGAAATAAAATAAATTAAG
TACAACCTAAAATATGTAAATGAGCATATTTAAAATAGAATAAATTATCAGCAGAGTTAA
AAAAAATATAAAAAATTTCCATCACTAAGCAACCATAAGAAACATATTAAACCAAAATAA
GTATGAACAAAAAGCTATTATCATAGTTGTCTCTTAAAAAAATGAAAAGCAAAATAAGTT
CATAAAGCAATAATTAATTTTAATTGAAAATGAAATACATTCAAAAGTTTGAAAAATGTT
TGATTATTTTTTAAAGTATAAAGACAGTCATAAATTATAATCTAAACACTTTTGTTTTGT
TTAATATAGGTTAAGGCTGACTCTAAGGCAGTTAAGGAATTCAGAAAATCTTTGACTAGT
TTGGGTGACTTATTCGTCAACGATGCTTTCGGTACCGCTCACAGAGCTCACTCTTCCATG
GTCGGTGTTGATCACAAAATCAGAGCTGCTGGTTACCTCTTGAAGAGAGAATTAGACTAC
TTCAGTAAGGCTTTGGAATCCCCTAACAGACCTTTCTTAGTTGTCTTAGGTGGTGCTAAG
GTCAAGGATAAAATCTAATTGATTGAAAGTATGCTTGACAAGGTCGATGAAATGATCATT
GGTGGTGGTATGGCCTTCACTTTCTTGAAGAAAATCCACAATATTGAAATTGGTAACTCC
CTCTTCGACGAAGAAGGTTATAAGATTGTTGACCAATTGTTAGAAAAGGCTAAAGCTAAG
AATGTCAAGATCCATTTACCAGTTGATTTCTTGTGCGGTGACTCACTTGAAGCCAACGCT
AACACCCGTAGCTTTGACTTAAAGAGTGGTATCCCTGCTGGATGGATTGGTTTAGATGCT
GGTCCTAAGACTATGGCTGAAAACGCTGAAGCTGTTGCCCGTGCTAACACTATTGTCTGG
AATGGTCCTTAAGGTAGATTCGAAGTTGATAAGTTTAAAGTAGGATCTTCTGACCTTCTC
AAGCACGTTGCTACTAGAACTTCCTAAGGAGCTACTTCTATTATTGGTGGTGGTGACACT
GTCAATCTTGTTCAACAAGAAAAGGCAACTCAAAAAGTCAGCCACGTCTCTACTGGTGGT
GGTGCATCTCTTGAACTTCTTGAAGGTAAAGTCCTTCCTGGTGTTGCTTATCTTACTGAT
ATTGACTAACTTTGA