Identifiers and Description

Gene Model Identifier

TTHERM_00705040

Standard Name

PELO1 (PELOta 1)

Aliases

PreTt26859 | 111.m00080 | 3744.m00001

Description

eRF1 domain 3 family protein; homolog of protein pelota; functions in mRNA surveillance pathways of non-stop and no-go decay

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• Dom34-Hbs1 complex (IDA) | GO:1990533 | Ref:SUPR000381
• cytoplasm (IDA) | GO:0005737 | Ref:SUPR000381

Domains

• ( PF03463 ) eRF1 domain 1
• ( PF03464 ) eRF1 domain 2
• ( PF03465 ) eRF1 domain 3
• ( TIGR00111 ) probable translation factor pelota
• ( TIGR00108 ) peptide chain release factor eRF/aRF,

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.1%

TetraMine Data

TTHERM_00705040

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_17708.1	9.997093137033517e-262	eRF1 domain 3 family protein ( 447 aa)
DictyBase	DDB_G0280447	5.000356947592888e-100	pelo on chromosome: 3 position 3368362 to 3369914
WormBase	WBGene00011280	9.999030951775615e-88	Uncharacterized protein R74.6 status:Confirmed UniProt:P 50444 protein_id:CAA85277.1
Oxytricha	Contig17990.0.g10	1.999469658314961e-75	eRF1 domain 2
SGD	YNL001W	3.000235161122315e-61	DOM34 Protein that, with bindi ng partner Hbs1p, facilitates ribosomal subunit dissociation when translation is stalled; required for RNA cleavage in n o-go decay, but reports confli ct on endonuclease activity; P elota ortholog
Stentor Coeruleus	SteCoe_37274	2.2273635617957438e-39

General Information

No Data fetched for General Information

Associated Literature

1. Ref:SUPR000381

Sequences

>TTHERM_00705040(coding)
ATGAGAATTATAAAAAGATATATTAGCAAGGGCGAAGGCTATTTAACTTTAGTTCCTACT
GAGGAAGAAGATTACTGGCACATTTATAACTTAGTTTCTAACGGTGATATTGTCCGTTCT
GCAACTTTCAGAAAGATAACCAAGGAGTCAAAGACAGGAGTTAAAGATGTCATTAAAAAG
AAAATTACTCTCACTTTGAAGATCGTTGCTATTAATTACTATGCAGGCGAGTTCCTGCAA
CTTTCTTTGAAGGGAAGAAACATAAAAGAAAATGATTACCTAAAGATGGGTTAATTCCAT
ACTTTTAATTTAGAATTAGACTAGCAGATTACTATCATTAAATAAAATTGGGATTCTTTC
CATTTTAAGATTATTAAGGATATTTCTGACCCTACTCATGATTCAGAACTAGCTGCATTT
GTTATGGATGAAGGAATAGCACATTTGTGTTTCATAAAATCTTCAATTACAATAATGAAG
CATAAAATAGAAAAGCACATACCTAAGAAGAAGAGTGGAGCCGAGCAACATGACAAGGCA
ATGGAAAAGTTCTTCGAAACCTGCTTTGAGTATTTGGTAACTGTTAATTATGATTAAATA
AAGTGCCTTGTTATTGCTTCTCCTGGTTATGTGAAAGATGATTTCTACAAATATATATAA
GATTAGTTGCAGAGAGCGGATCTAGCTGCATTCAACAAGAGGTCAAACTTCCTTTAAAAG
ATAGTCAGAGCTAAGTCATCAACAGGATATTTGAATAGTTTAAGTGAAGTATTGAGTGAC
CCCACTATCTAAGAGTAGTTAAAAGATACAAAGGCTATCAAAGAAGTGAGAGCTCTAGAT
GATTTTTACAAGGTTATGAGTAAAGATCCTGATATGGTTTGCTATGGATAAAAGCATGTA
TTTAAAGCATACGAAGATAATGCTATTTAAACCTTACTTTTGAGTGACAGTCTTTTTAGA
ATTAAAGATTTGAGTTAACGTAAAAAATTCAATAATTTGATCGATGACACTAAGAAGAAG
GGAATTGACTCTTTGATTTTCTCTAGTTTGCACAGTAGTGGAGAAAAATTAAATAATTTA
ACAGGTATAGCAGCTATCCTTAGATATCCTATCCCTTATGAAGACGAAGAGATGGAGTAA
TCTGAAGAAATAGTTGAAAATTTTAGAGTAAAGATAGAAGAAAGAGAAGAAGTCGAAGAC
GAAAAATCCATTATGGGAGATGATGAAAAATTAGAAGCTGAAAGAATAGCAAAAGAGTTA
GAAGCATTTTCTTTAGATAATTTAGACGAAGAACAAAAGCAAGATGAAGACGAAAATCTT
TGA

>TTHERM_00705040(protein)
MRIIKRYISKGEGYLTLVPTEEEDYWHIYNLVSNGDIVRSATFRKITKESKTGVKDVIKK
KITLTLKIVAINYYAGEFLQLSLKGRNIKENDYLKMGQFHTFNLELDQQITIIKQNWDSF
HFKIIKDISDPTHDSELAAFVMDEGIAHLCFIKSSITIMKHKIEKHIPKKKSGAEQHDKA
MEKFFETCFEYLVTVNYDQIKCLVIASPGYVKDDFYKYIQDQLQRADLAAFNKRSNFLQK
IVRAKSSTGYLNSLSEVLSDPTIQEQLKDTKAIKEVRALDDFYKVMSKDPDMVCYGQKHV
FKAYEDNAIQTLLLSDSLFRIKDLSQRKKFNNLIDDTKKKGIDSLIFSSLHSSGEKLNNL
TGIAAILRYPIPYEDEEMEQSEEIVENFRVKIEEREEVEDEKSIMGDDEKLEAERIAKEL
EAFSLDNLDEEQKQDEDENL

>TTHERM_00705040(gene)
ATGAGAATTATAAAAAGATATATTAGCAAGGGCGAAGGCTATTTAACTTTAGTTCCTACT
GAGGAAGAAGATTACTGGCACATTTATAACTTAGTTTCTAACGGTGATATTGTCCGTTCT
GCAACTTTCAGAAAGATAACCAAGGAGTCAAAGACAGGAGTTAAAGATGTCATTAAAAAG
AAAATTACTCTCACTTTGAAGATCGTTGCTATTAATTACTATGCAGGCGAGTTCCTGCAA
CTTTCTTTGAAGGGAAGAAACATAAAAGAAAATGATTACCTAAAGATGGGTTAATTCCAT
ACTTTTAATTTAGAATTAGACTAGCAGATTACTATCATTAAATAAAATTGGGATTCTTTC
CATTTTAAGATTATTAAGGATATTTCTGACCCTACTCATGATTCAGAACTAGCTGCATTT
GTTATGGATGAAGTAATCAAAATTTTTTATTAAATTTAAAGTTTGTTTGAATTTCAACAA
CTAAGAAAAGAAATGTTAAATGCTTTTTGAAATATAGAAAAAAATTAATTAGTTTGTTTT
TGTAATGATGAATTATTTAATAAATGATAGGGAATAGCACATTTGTGTTTCATAAAATCT
TCAATTACAATAATGAAGCATAAAATAGAAAAGCACATACCTAAGAAGAAGAGTGGAGCC
GAGCAACATGACAAGGCAATGGAAAAGTTCTTCGAAACCTGCTTTGAGTATTTGGTAACT
GTTAATTATGATTAAATAAAGTGCCTTGTTATTGCTTCTCCTGGTTATGTGAAAGATGAT
TTCTACAAATATATATAAGATTAGTTGCAGAGAGCGGATCTAGCTGCATTCAACAAGAGG
TCAAACTTCCTTTAAAAGATAGTCAGAGCTAAGTCATCAACAGGATATTTGAATAGTTTA
AGTGAAGTATTGAGTGACCCCACTATCTAAGAGTAGTTAAAAGATACAAAGGCTATCAAA
GAAGTGAGAGCTCTAGATGATTTTTACAAGGTATCAAAGATATGAATTATTTTATTAAAT
AGAATGAAAGTGTTTTTATTTATTGCTTTAAATAATTTTATTAATTACAAAATAGGTTAT
GAGTAAAGATCCTGATATGGTTTGCTATGGATAAAAGCATGTATTTAAAGCATACGAAGA
TAATGCTATTTAAACCTTACTTTTGAGTGACAGTCTTTTTAGAATTAAAGATTTGAGTTA
ACGTAAAAAATTCAATAATTTGATCGATGACACTAAGAAGAAGGGAATTGACTCTTTGAT
TTTCTCTAGTTTGCACAGTAGTGGAGAAAAATTAAATAATTTAACAGGTATAGCAGCTAT
CCTTAGATATCCTATCCCTTATGAAGACGAAGAGATGGAGTAATCTGAAGAAATAGTTGA
AAATTTTAGAGTAAAGATAGAAGAAAGAGAAGAAGTCGAAGACGAAAAATCCATTATGGG
AGATGATGAAAAATTAGAAGCTGAAAGAATAGCAAAAGAGTTAGAAGCATTTTCTTTAGA
TAATTTAGACGAAGAACAAAAGCAAGATGAAGACGAAAATCTTTGA