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Nabeel-Shah S, Garg J, Saettone A, Ashraf K, Lee H, Wahab S, Ahmed N, Fine J, Derynck J, Pu S, Ponce M, Marcon E, Zhang Z, Greenblatt JF, Pearlman RE, Lambert JP, Fillingham J (2021) Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila. Nucleic acids research ( ): PUBMED:34086947
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Identifiers and Description
Gene Model Identifier
TTHERM_00283530
Standard Name
PDD2 (Programmed DNA Degradation)
Aliases
PreTt04892 | 25.m00356 | 3694.m00139
Description
PDD2 programmed DNA degradation 2 protein; Programmed DNA degradation 2 protein; novel- developmentally regulated protein that localizes in DNA elimination structures; required for successful DNA elimination; binds Pdd1p; null mutant inviable
Ref:10805754: Nikiforov MA, Gorovsky MA, Allis CD (2000) A novel chromodomain protein, pdd3p, associates with internal eliminated sequences during macronuclear development in Tetrahymena thermophila. Molecular and cellular biology 20(11):4128-34
Ref:10557212: Nikiforov MA, Smothers JF, Gorovsky MA, Allis CD (1999) Excision of micronuclear-specific DNA requires parental expression of pdd2p and occurs independently from DNA replication in Tetrahymena thermophila. Genes & development 13(21):2852-62
Ref:9409671: Smothers JF, Mizzen CA, Tubbert MM, Cook RG, Allis CD (1997) Pdd1p associates with germline-restricted chromatin and a second novel anlagen-enriched protein in developmentally programmed DNA elimination structures. Development (Cambridge, England) 124(22):4537-45