Identifiers and Description

Gene Model Identifier

TTHERM_01107420

Standard Name

PCNA1 (proliferating cell nuclear antigen 1)

Aliases

PreTt28091 | 237.m00048 | 3794.m00183

Description

proliferating cell nuclear antigen (pcna)

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• PCNA complex (IEA) | GO:0043626

Molecular Function

• DNA polymerase processivity factor activity (IEA) | GO:0030337
• DNA binding (IEA) | GO:0003677

Biological Process

• regulation of DNA replication (IEA) | GO:0006275

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 11.1%

TetraMine Data

TTHERM_01107420

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_20275.1	3.9987282255476324e-176	proliferating cell nuclear ant igen (pcna) (262 aa)
Oxytricha	Contig12091.0.g3	8.003265703977305e-104	Proliferating cell nuclear ant igen, N-terminal domain
WormBase	WBGene00003955	2.9993408039826107e-81	locus:pcn-1 Proliferating ce ll nuclear antigen status:Co nfirmed UniProt:O02115 pro tein_id:CCD66765.1
DictyBase	DDB_G0287607	2.0001503375893664e-79	pcna on chromosome: 5 position 463300 to 464157
SGD	YBR088C	3.0000115468388957e-66	POL30 Proliferating cell nucle ar antigen (PCNA), functions a s the sliding clamp for DNA po lymerase delta; may function a s a docking site for other pro teins required for mitotic and meiotic chromosomal DNA repli cation and for DNA repair
Stentor Coeruleus	SteCoe_31816	4.0795586671775603e-41

General Information

No Data fetched for General Information

Associated Literature

1. Ref:23884606: Gao S, Xiong J, Zhang C, Berquist BR, Yang R, Zhao M, Molascon AJ, Kwiatkowski SY, Yuan D, Qin Z, Wen J, Kapler GM, Andrews PC, Miao W, Liu Y (2013) Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation. Genes & development 27(15):1662-79

Sequences

>TTHERM_01107420(coding)
ATGTTTGAAGCTAAATTACAATAAGGTGTTATTTTCAAAAAAATCGTCGATGCTATCAAG
GATTTAGTTAAATCAGTTAATATCGATGCTAGCACTAGTGGTCTTTCCATGCAAGCTATG
GATTCAGCTCACGTTGCTTTGGTTTCCCTCAAGTTAAATGAAAATGGTTTCAAGGATTAT
AGATGTGACAGACCAATCACTCTTGGTCTTTCTATTGAAAACCTTTCCAAGATCCTCAAG
TGTGCTGGAAATGATGACACTATTACCTTATAAACTGATGAAGAAGAACCTTCTTCCCTT
AAATTCTTCTTTGAAAATTAATAGGCCTCTAAGATCTCCGAATTTAGTTTGAACTTAATG
TCATTAGATAGTGAATCTTTGGGTATCCCCGACACCGATTATTCTTCTGTTATTCAAATG
TCCTCAGCTGAATTCTCTAGAATCTGCAAGGAACTTAGTTCTATTTCTGAAACAGTTGAA
ATTGAAACTAGCAAAGAATCTGTTAAGTTTAGCGTTTAAGGAGATATTGGTGCTGGTTCA
ATCACTGTCAAGAATAACTAAAGTGATAAAGATGTTGACCGTGTTGATTTACAAATTGAT
TAACCCGTTAAGTTAACCTTCGCTCTTAGATATTTGAATATGTTCAATAAGGCTGTCTCT
CTTAGCAGTACTGTTAGTTTAAATATGTCTGAAGAAAATCCTCTTATGGTTGAATATAAA
ATCGATGATCTTGGTTCTCTTAGATTCTATCTTGCTCCTAAGATTTCTGATGAAGAAAGT
AGTTGA

>TTHERM_01107420(protein)
MFEAKLQQGVIFKKIVDAIKDLVKSVNIDASTSGLSMQAMDSAHVALVSLKLNENGFKDY
RCDRPITLGLSIENLSKILKCAGNDDTITLQTDEEEPSSLKFFFENQQASKISEFSLNLM
SLDSESLGIPDTDYSSVIQMSSAEFSRICKELSSISETVEIETSKESVKFSVQGDIGAGS
ITVKNNQSDKDVDRVDLQIDQPVKLTFALRYLNMFNKAVSLSSTVSLNMSEENPLMVEYK
IDDLGSLRFYLAPKISDEESS

>TTHERM_01107420(gene)
ATGTTTGAAGCTAAATTACAATAAGGTGTTATTTTCAAAAAAATCGTCGATGCTATCAAG
GATTTAGTTAAATCAGTTAATATCGATGCTAGCACTAGTGGTCTTTCCATGCAAGCTATG
GATTCAGCTCACGTTGCTTTGGTTTCCCTCAAGTTAAATGAAAATGGTTTCAAGGATTAT
AGATGTGACAGACCAATCACTCTTGGTCTTTCTATTGAAAACCTTTCCAAGATCCTCAAG
TGTGCTGGAAATGATGACACTATTACCTTATAAACTGATGAAGAAGAACCTTCTTCCCTT
AAATTCTTCTTTGAAAATTAATGTAATTTATTAGGACAAAAATAATTATTTTATTCTAAA
CTTTGTACATGTTTTCTTTTGGAATAAATTAAACTGAACATATTTAGAATACTCTACTTT
TACAATACTCTACTTTTATAATATTATATAATATATCCTTATTCATTCTATTAATCATTT
GATACAATTTTTTCAATGCTAATCAAAATTAAAATTATTTTTTTTATTATTTTGTAGAGG
CCTCTAAGATCTCCGAATTTAGTTTGAACTTAATGTCATTAGATAGTGAATCTTTGGGTA
TCCCCGACACCGATTATTCTTCTGTTATTCAAATGTCCTCAGCTGAATTCTCTAGAATCT
GCAAGGAACTTAGTTCTATTTCTGAAACAGGTAAACAATAATAGATGTTAAATTCAAAGA
AGTAGATCATACTTAATCTAGATAATAATGTTTAAACTTAAAAATTAAGAAGTAGCTCTT
AAAAATTTTGAAAATTAGTTAAGTTAAGTATGGTTGACCTTCACTAAATGCATTAGATTA
TTATTAGATATATAAATTAATATTGTTTTTAAAAAATAAAATAGTTGAAATTGAAACTAG
CAAAGAATCTGTTAAGTTTAGCGTTTAAGGAGATATTGGTGCTGGTTCAATCACTGTCAA
GAATAACTAAAGTGATAAAGATGTTGACCGTGTTGATTTACAAATTGATTAACCCGTTAA
GTTAACCTTCGCTCTTAGATATTTGAATATGTTCAATAAGGCTGTCTCTCTTAGCAGTAC
TGTTAGTTTAAATATGTCTGAAGAAAATCCTCTTATGGTTGAATATAAAATCGATGATCT
TGGTTCTCTTAGATTCTATCTTGCTCCTAAGATTTCTGATGAAGAAAGTAGTTGA