Identifiers and Description

Gene Model Identifier

TTHERM_00726470

Standard Name

PARP2 (Poly(ADP-Ribosyl) transferase 2)

Aliases

PreTt21912 | 117.m00164

Description

PARP2 poly(ADP-ribose) polymerase family WGR domain protein; WGR domain containing protein; homolog to human PARP2

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• NAD+ ADP-ribosyltransferase activity (IEA) | GO:0003950

Biological Process

• protein ADP-ribosylation (IEA) | GO:0006471

Domains

• ( PF05406 ) WGR domain
• ( PF00644 ) Poly(ADP-ribose) polymerase catalytic domain
• ( PF02877 ) Poly(ADP-ribose) polymerase, regulatory domain

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 11%

TetraMine Data

TTHERM_00726470

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_04636.1	9.997093137033517e-262	WGR domain-containing protein (625 aa)
Oxytricha	Contig12012.0.g59	2.000234809436283e-103	Poly(ADP-ribose) polymerase ca talytic domain
DictyBase	DDB_G0292820	4.001158060863534e-95	adprt2 on chromosome: 6 positi on 2124835 to 2127096
WormBase	WBGene00004049	6.997568408582301e-83	locus:pme-1 Poly(ADP-ribose) polymerase pme-1 status:Con firmed UniProt:Q9N4H4 prot ein_id:CCD73512.1
Stentor Coeruleus	SteCoe_24990	5.96629836401057e-72

General Information

No Data fetched for General Information

Associated Literature

1. Ref:30796450: Ashraf K, Nabeel-Shah S, Garg J, Saettone A, Derynck J, Gingras AC, Lambert JP, Pearlman RE, Fillingham J (2019) Proteomic analysis of histones H2A/H2B and variant Hv1 in Tetrahymena thermophila reveals an ancient network of chaperones. Molecular biology and evolution ( ):

Sequences

>TTHERM_00726470(coding)
ATGTCTACAAGATAAACAAGAGGCTAAAAAAAAGCCGAAGAAGACAAAAAGAATGGAGTT
GATTCTAAACCCAAACAAACTAAAGACGATAGTGAATCTGAAGAAGATGAGCCTAAGGCC
AAAAGAGCTCCAAGAGGAGCTGCTGCAAAAAAGGCAGCTGAAAAAAAGAAAGAAAAAGAA
GAGCAGTAATAAAAAAACAACAAAAAGGATGATGATGAAGATGAAAAAGACAAAGATACC
AAGACAAAAAAAGCATCAAAGGCAGCAAAAAGTGTTGATACTAAAGATGATAAAAAGCCT
GATGACAAGAAAGATACTAAAGCAGATGATCCTGATACTTCTAAAAAATAAAATACAGGC
GATGATGCTGCTGATACTAGTAATATCAAAAAAGAAATAATTGAAGGAGCAGCTCCAGTT
GATGAACACTGTCCTAGAAAAGATGTTGAAGTTTATTATACCAAGAATAAAATATACTCA
GCTAAACTTAATTAGGCTAACATGAGCAACAACAATAACAAATTTTATATTATTTAAGTG
CTCAAAGTGAAAGGAAAAGATTAATATTATCACTATAACCGTTGGGGTAGAGTAGGTGTT
CCTGGGTAAAATTCTTGTAGGGGTCCCTTTACAGCTGAATAAGCTTGTTAAGAATACGAA
AATAAGCTAAAAGATAAAACTAAAAAAGGAGAATATCGTGTCCTTGATATGGATTACGGT
TAAGATGCCACTTTAGATGAATTAGATGATGTTATGAAAAAAGATGCTGAAACTTGTAAA
CTACCCAAAGAAGTTATTAGCCTTATTTCTTTAATTTTTGATATGAAAATGATCAATAAC
TAAATGAAAGAAATTGGTTATGATGTTAAGAAAATGCCTCTTGGTAAGCTCTCTAAAGAA
AATATTAATAAAGCTTATGGTATGCTTAAATAACTTTATGAAGAAGTAGAAAAACCCAAA
AAGAACAAAGATAAAATTGAAGAATTATGTAATGAGTTTTATTCATACATTCCACATGAT
TTTGGCTTTAAAAAAATGGCTTCATTTATACTTGATGATGCTAAAAAAGTAAAAGAAAAA
TTAGAAATGATTGAATCAATTTAGAATATCTAAATTGCAACTAAGTTAATTGAAGATAAA
AAGCAAGGAAAAGATGGCTAGTAAATTAATTAAATTCAATCTAATTATGAAAAGCTCAAA
TGCAAAATTGAACCTGTTAAAGATTAAAAAGTTCGTAAAATTATTGAAGACTATCTCAAG
AATACTCATGCATCTACTCACAACTAATATGGCTTAACAATTGATGAGATTTTTGAAGTA
GAAAGAGAAGGCGAAAATGATCGCTACTTGAAGGATATCAAAAATAAAATGCTTCTTTGG
CATGGTTCTCGTCTTACAAATTTTGTTGGTATATTGTCTTAAGGTCTACGTATTGCTCCT
CCAGAAGCTCCTGTTACTGGTTATATGTTTGGTAAAGGTGTCTATTTTGCTGATATGTGT
AGTAAATCTGCCAATTATTGTTTCACAAATAAAGCAAATAATACAGGTTTAATGCTACTC
TGTGAAGTCGCTTTAGGTGAGATGAATGATAAGTACTATGCAGATTACTATGCCTCTAAC
TTACCTGCTGGTAAGCACAGTACTAGAGGTAGAGGTAAAACAGCCCCTCCTGAGAGCTCG
TATGTTACTATTTATGATGACGTATAAGTTCCTGTTGGTAAGGGCGAACCTTAAGTTTTT
CCTAATGGTTAATATGGTTCATTGCTATACAATGAATTTATTGTTTATGATATCAGATAA
ATCAAGGTAAAATATCTGTTAAGATTAACATTCAATTATAAATATTGA

>TTHERM_00726470(protein)
MSTRQTRGQKKAEEDKKNGVDSKPKQTKDDSESEEDEPKAKRAPRGAAAKKAAEKKKEKE
EQQQKNNKKDDDEDEKDKDTKTKKASKAAKSVDTKDDKKPDDKKDTKADDPDTSKKQNTG
DDAADTSNIKKEIIEGAAPVDEHCPRKDVEVYYTKNKIYSAKLNQANMSNNNNKFYIIQV
LKVKGKDQYYHYNRWGRVGVPGQNSCRGPFTAEQACQEYENKLKDKTKKGEYRVLDMDYG
QDATLDELDDVMKKDAETCKLPKEVISLISLIFDMKMINNQMKEIGYDVKKMPLGKLSKE
NINKAYGMLKQLYEEVEKPKKNKDKIEELCNEFYSYIPHDFGFKKMASFILDDAKKVKEK
LEMIESIQNIQIATKLIEDKKQGKDGQQINQIQSNYEKLKCKIEPVKDQKVRKIIEDYLK
NTHASTHNQYGLTIDEIFEVEREGENDRYLKDIKNKMLLWHGSRLTNFVGILSQGLRIAP
PEAPVTGYMFGKGVYFADMCSKSANYCFTNKANNTGLMLLCEVALGEMNDKYYADYYASN
LPAGKHSTRGRGKTAPPESSYVTIYDDVQVPVGKGEPQVFPNGQYGSLLYNEFIVYDIRQ
IKVKYLLRLTFNYKY

>TTHERM_00726470(gene)
ATGTCTACAAGATAAACAAGAGGCTAAAAAAAAGCCGAAGAAGACAAAAAGAATGGAGTT
GATTCTAAACCCAAACAAACTAAAGACGATAGTGAATCTGAAGAAGATGAGCCTAAGGCC
AAAAGAGCTCCAAGAGGAGCTGCTGCAAAAAAGGCAGCTGAAAAAAAGAAAGAAAAAGAA
GAGCAGTAATAAAAAAACAACAAAAAGGATGATGATGAAGATGAAAAAGACAAAGATACC
AAGACAAAAAAAGCATCAAAGGCAGCAAAAAGTAAATAGATAATAAATTATTAGATTAAA
AAAGTAATTTACTTTATTTTTATAATTTAGGTGTTGATACTAAAGATGATAAAAAGCCTG
ATGACAAGAAAGATACTAAAGCAGATGATCCTGATACTTCTAAAAAATAAAATACAGGCG
ATGATGCTGCTGATACTAGTAATATCAAAAAAGAAATAATTGAAGGAGCAGCTCCAGTTG
ATGAACACTGTCCTAGAAAAGATGTTGAAGTTTATTATACCAAGAATAAAATATACTCAG
CTAAACTTAATTAGGCTAACATGAGCAACAACAATAACAAATTTTATATTATTTAAGTGC
TCAAAGTGAAAGGAAAAGATTAATATTATCACTATAACCGTTGGGGTAGAGTAGGTGTTC
CTGGGTAAAATTCTTGTAGGGGTCCCTTTACAGCTGAATAAGCTTGTTAAGAATACGAAA
ATAAGCTAAAAGATAAAACTAAAAAAGGAGAATATCGTGTCCTTGATATGGATTACGGTT
AAGATGCCACTTTAGATGAATTAGATGATGTTATGAAAAAAGATGCTGAAACTTGTAAAC
TACCCAAAGAAGTTATTAGCCTTATTTCTTTAATTTTTGATATGAAAATGATCAATAACT
AAATGAAAGAAATTGGTTATGATGTTAAGAAAATGCCTCTTGGTAAGCTCTCTAAAGAAA
ATATTAATAAAGCTTATGGTATGCTTAAATAACTTTATGAAGAAGTAGAAAAACCCAAAA
AGAACAAAGATAAAATTGAAGAATTATGTAATGAGTTTTATTCATACATTCCACATGATT
TTGGCTTTAAAAAAATGGCTTCATTTATACTTGATGATGCTAAAAAAGTAAAAGAAAAAT
TAGAAATGATTGAATCAATTTAGAATATCTAAATTGCAACTAAGTTAATTGAAGATAAAA
AGCAAGGAAAAGATGGCTAGTAAATTAATTAAATTCAATCTAATTATGAAAAGCTCAAAT
GCAAAATTGAACCTGTTAAAGATTAAAAAGTTCGTAAAATTATTGAAGACTATCTCAAGA
ATACTCATGCATCTACTCACAACTAATATGGCTTAACAATTGATGAGATTTTTGAAGTAG
AAAGAGAAGGCGAAAATGATCGCTACTTGAAGGATATCAAAAATAAAATGCTTCTTTGGC
ATGGTTCTCGTCTTACAAATTTTGTTGGTATATTGTCTTAAGGTCTACGTATTGCTCCTC
CAGAAGCTCCTGTTACTGGTTATATGTTTGGTAAAGGTGTCTATTTTGCTGATATGTGTA
GTAAATCTGCCAATTATTGTTTCACAAATAAAGCAAATAATACAGGTTTAATGCTACTCT
GTGAAGTCGCTTTAGGTGAGATGAATGATAAGTACTATGCAGATTACTATGCCTCTAACT
TACCTGCTGGTAAGCACAGTACTAGAGGTAGAGGTAAAACAGCCCCTCCTGAGAGCTCGT
ATGTTACTATTTATGATGACGTATAAGTTCCTGTTGGTAAGGGCGAACCTTAAGTTTTTC
CTAATGGTTAATATGGTTCATTGCTATACAATGAATTTATTGTTTATGATATCAGATAAA
TCAAGGTAAAATATCTGTTAAGATTAACATTCAATTATAAATATTGA