Identifiers and Description

Gene Model Identifier

TTHERM_01106120

Standard Name

NTG1 (eNdonuclease Three-like Glycosylase)

Aliases

PreTt04526 | 236.m00030 | 3800.m00152

Description

NTG1 base excision DNA repair protein HhH-GPD family protein; HhH-GPD superfamily base excision DNA repair protein; similar to yeast NTG1- a DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair; contains an endonuclease C3 domain and an Fe-sulfur binding domain

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• DNA binding (IEA) | GO:0003677

Biological Process

• base-excision repair (IEA) | GO:0006284

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.3%

TetraMine Data

TTHERM_01106120

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_20657.1	1.999807452113044e-171	HhH-GPD superfamily base excis ion DNA repair protein (376 aa )
DictyBase	DDB_G0277247	7.000176714425793e-58	apnB on chromosome: 2 position 7816486 to 7817535
WormBase	WBGene00011201	9.997652352281279e-57	locus:nth-1 Probable endonuc lease III homolog status:Con firmed UniProt:P54137 prot ein_id:CBK55598.1
Oxytricha	Contig9879.0.0.g14	1.9992362000979228e-56	HhH-GPD superfamily base excis ion DNA repair protein
SGD	YAL015C	4.001416569413617e-37	NTG1 DNA N-glycosylase and apu rinic/apyrimidinic (AP) lyase involved in base excision repa ir; acts in both nucleus and m itochondrion; creates a double -strand break at mtDNA origins that stimulates replication i n response to oxidative stress
Stentor Coeruleus	SteCoe_29630	1.185064864233981e-27

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_01106120(coding)
ATGCCTCCAAAACAATAAAAAACCAAAAAAAATAAAAAAGCTGTTGATTTGCCAGAAAAT
GATAAAGATAAAGAAGAAATACTCGAGAATATTAAGATTACAGAATAAAATGATGAATTA
AAATCTGAAATAGATAGCTTGGATTAATTTAAATTTTAAAAAGAAGAAGTGAACAATCCC
ATTAAAAAAACAAGAAAGCAAAAATTATAAATAGAATATGAATAAAGTGTTAATAAAGTT
GAAAGAGCTTCCAGAAAAAAATTATTAGATAAAAACATTGATGAAGATGATAAAAATTAA
AAATAGCAAACAAATAATTAATTAGACAATTAAAATGGCAATGAAGAGAAAAGTGAATAA
GTAAAAAATTAATCTGAAGAAAATAATAATTAGAATGAATAAAAGAAAAAGGGAAAGTAT
AATTGTAGAGAAAATTATGAAGAAATTTACAGTTTAATAAAAGGATATAGAGATACTCAT
ACAGCTCCAGTAGATACTTTAGGATGTGATCTCTAAGGGGATGAATCTTTACCAACAAAT
GATAGAAATTTTTAAAAATTAATGGCAATTATATTGAGTGTATAGACAAAAGATGAAACA
ACTGACCTAGTAATGAAGAAAGTAGTAAAAGAGAAAATAACTATTGATAAAGCCGTTGAA
ATTCCATCGAGCGAATTAAAAGAAATAATTAAATAAGTTAACTTTAATGGAAAAAAAGTA
GAATATATTAAGAACGCAGCAGAAGTTATAAAAAATACATATAACTATGTTATACCTGAT
TAGTATGAAGATTTAATTAAAATCAAGGGAATAGGTCCAAAAGTTGCAAATTTATTTTTG
TAATGTGCATATAATAAAACTGTAGGAATAGCTGTAGACACGCATGTTCATAGAATATCT
AATAGGCTTGAATGGGTTTCAACAAAAACTCCTGAATAAACTCGAATTGAATTAGAAAAA
TTGCTTGATAAAAAGTATTGGGAAGATGTAAACAATCTGTTAGTTGGATATGGTTAATCA
GTTTGTAAGCCTTAAAATCCCTAGTGCTAAATATGTCCTGTAAAAGATAAGTGTCCTGAG
GGTAGAAGAAGATTAAAAGGAAAGAAAAAAATATGA

>TTHERM_01106120(protein)
MPPKQQKTKKNKKAVDLPENDKDKEEILENIKITEQNDELKSEIDSLDQFKFQKEEVNNP
IKKTRKQKLQIEYEQSVNKVERASRKKLLDKNIDEDDKNQKQQTNNQLDNQNGNEEKSEQ
VKNQSEENNNQNEQKKKGKYNCRENYEEIYSLIKGYRDTHTAPVDTLGCDLQGDESLPTN
DRNFQKLMAIILSVQTKDETTDLVMKKVVKEKITIDKAVEIPSSELKEIIKQVNFNGKKV
EYIKNAAEVIKNTYNYVIPDQYEDLIKIKGIGPKVANLFLQCAYNKTVGIAVDTHVHRIS
NRLEWVSTKTPEQTRIELEKLLDKKYWEDVNNLLVGYGQSVCKPQNPQCQICPVKDKCPE
GRRRLKGKKKI

>TTHERM_01106120(gene)
ATGCCTCCAAAACAATAAAAAACCAAAAAAAATAAAAAAGCTGTTGATTTGCCAGAAAAT
GATAAAGATAAAGAAGAAATACTCGAGAATATTAAGATTACAGAATAAAATGATGAATTA
AAATCTGAAATAGATAGCTTGGATTAATTTAAATTTTAAAAAGAAGAAGTGAACAATCCC
ATTAAAAAAACAAGAAAGCAAAAATTATAAATAGAATATGAATAAAGTGTTAATAAAGTT
GAAAGAGCTTCCAGAAAAAAATTATTAGATAAAAACATTGATGAAGATGATAAAAATTAA
AAATAGCAAACAAATAATTAATTAGACAATTAAAATGGCAATGAAGAGAAAAGTGAATAA
GTAAAAAATTAATCTGAAGAAAATAATAATTAGAATGAATAAAAGAAAAAGGGAAAGTAT
AATTGTAGAGAAAATTATGAAGAAATTTACAGTTTAATAAAAGGATATAGAGATACTCAT
ACAGCTCCAGTAGATACTTTAGGATGTGATCTCTAAGGGGATGAATCTTTACCAACAAAT
GATAGAAATTTTTAAAAATTAATGGCAATTATATTGAGTGTATAGACAAAAGATGAAACA
ACTGACCTAGTAATGAAGAAAGTAGTAAAAGAGAAAATAACTATTGATAAAGCCGTTGAA
ATTCCATCGAGCGAATTAAAAGAAATAATTAAATAAGTTAACTTTAATGGAAAAAAAGTA
GAATATATTAAGAACGCAGCAGAAGTTATAAAAAATACATATAACTATGTTATACCTGAT
TAGTATGAAGATTTAATTAAAATCAAGGGAATAGGTCCAAAAGTTGCAAATTTATTTTTG
TAATGTGCATATAATAAAACTGTAGGAATAGCTGTAGACACGCATGTTCATAGAATATCT
AATAGGCTTGAATGGGTTTCAACAAAAACTCCTGAATAAACTCGAATTGAATTAGAAAAA
TTGCTTGATAAAAAGTATTGGGAAGATGTAAACAATCTGTTAGTTGGATATGGTTAATCA
GTTTGTAAGCCTTAAAATCCCTAGTGCTAAATATGTCCTGTAAAAGATAAGTGTCCTGAG
GGTAGAAGAAGATTAAAAGGAAAGAAAAAAATATGA