Identifiers and Description

Gene Model Identifier

TTHERM_01027700

Standard Name

NRK9 (NIMA-Related Kinase)

Aliases

PreTt17999 | 203.m00054 | 3803.m00213

Description

NRK9 Serine/Threonine kinase domain protein; NIMA-Related Kinase

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• protein kinase activity (IEA) | GO:0004672
• ATP binding (IEA) | GO:0005524
• protein binding (IEA) | GO:0005515
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.4%

TetraMine Data

TTHERM_01027700

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_20111.1	9.997093137033517e-262	protein kinase domain-containi ng protein (1875 aa)
Oxytricha	Contig4942.0.g74	4.000904604388404e-59	Protein kinase domain
WormBase	WBGene00021461	9.99893167504554e-35	locus:nekl-1 status:Partiall y_confirmed UniProt:Q6AW07 protein_id:CCD69902.1
DictyBase	DDB_G0289277	9.99893167504554e-35	nek4 on chromosome: 5 position 2561379 to 2563106
Stentor Coeruleus	SteCoe_11813	1.0806392777072785e-30
SGD	YHR102W	6.9997332827772725e-22	KIC1 Protein kinase of the PAK /Ste20 family, required for ce ll integrity; physically inter acts with Cdc31p (centrin), wh ich is a component of the spin dle pole body; part of the RAM network that regulates cellul ar polarity and morphogenesis

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_01027700(coding)
ATGGACGATACAATTTCTTCTTTTGGAACATTTGCTTCTCCAGTCAAGCCAAATTCTAAA
TTAAATGATTTCAAGATTCTATGTAAATTAGGCGAAGGATCATTTTCAACTGTGTTTAAA
GTACTCCGTTTAGTAGATAACAAGATTTATGCCATGAAGAAGGTTTAAATGAGCAGATTA
AATGAAAAGGAAAAAGGAAATTCTTTAAATGAAATAAGAATTTTAGCTTCAATAAAGTGC
GATCATATTATAGAATACAGAGACAGCTTTTTTGATGATTAATCAGACACACTTTGTATA
GTTATGGAGTATGCAGGTAGTGGTGATTTACTTCAAAAATTAAAAGAGTATAAGCTAATA
AATGAAAAATTACTTGAGGATGGATAAAATGAAACAAGTGAGAGCCAGGTAGAACAAGAT
TCATCTCCAAAAGAAGAAAGTGATAAAAGTTCTCGTTCTTAAGAGAAAAACAAGCGCATA
TACAACAAACTCAATTAATAAAATGAAAGTATTAAATCAAAGAAATCATCAATATAAGAA
AACTCAAGTAAGTCTGTGGTGTAAGATAAGCAATAATAGATGGTTTTTATGGATGAAGAG
TTGATTTGGGATTATTTTATTCAATGTTTGAAAGGTTTAAAGTGCTTGCATGACTTGAAA
ATCGTACATCGTGATTTAAAATGTGCAAATATATTTATAGGTGATAATAATATTATTAAA
ATTGGAGATCTAAATGTATCCAAAGTTACAAGAAGGCCAGAGTAAATGGCTAAAACGCAA
ACAGGTACTCCTTATTATACTGCACCTGAAGTGTGGAAAGGGTTGTCTTATAACTATAAA
AGCGATGTTTGGTCTTTGGGATGTATAATATATGAGCTTTCCGCTTAAAAGCATCCTTTT
AAAGGAAATACAATTGAAGGGCTATTTACTAATATAATGAAAGGATAGTATGAAAGAATA
CCAAGTTTTTATTCTGAAGAATTAGCTTTTGTTATATCTTAATGTTTGCTTTAGAATCCC
AAGCTGAGACCAGGATGCGATCAGCTTTTAAAATTGCCTGCATTTGCTTCAAGACTGTAA
AAATATGAAGAAAAGTATAGGTAGTATTTGCAAAATCATAACAAGTAAAAAATTCATTCT
AACTTCCTTAATGTGACATCGTAAAACCATCTTGAGTTTACCCCCTAAAGAGTATAAAAG
ACCAACACTGAAGGACCCCATCTTATCGATACTATTAATATGCCTTCTAACTTAAAATAG
TTGTCTGCTCTCTTACCTAAATCTAACTATGAAGATACCCCAATTTAACTTCCTTCAATA
AGTGAATTTGATGAAAATATTGTTAATAACAATAATCATTTGCACAATAAAAGCAACTTC
ATGAAATTAAGAGCTTCTGTTCAAAAAGTTTCTGAATTTGATTAGCTTGAGAAGATATCT
TCTGCAGATTCTTCATCATCATCTTCCTCACCATCAGCAGCTACAAACAGAATAACCAAG
AATTTCAAGGATAATAATGAACTGTAAAATGATCAATTAAAGACCTCGTAGATGCACCAA
GATAATATATTTTAAGCTTTATTGGACCTTCAACCAGCTGATATTCTTAATCAAAAATTA
ACTTTAACTTAGTAATAAAAGGAAACTACAAAATTAACAAATAAAAAGATGAGTTAGCTC
TAACCTTATCATGATTTAGTCAATGATTCTCCAATACGTTTTAATCTTCAAAAGGTATAG
ATGGAAAACAAAAATTAAGAGCAGAAAAGTGATGAAAAAAAAGAAAATAGCGAAAGAAAG
AATATAACTCTATAGAAAATAGATTTCATTAATGAGCAAAAGAATCACAGTGGCTTGAGT
TAAAATAATAATACTAAAAATACAATAAGTACAAATGCCCAGACTTTCAAAAATAATGAT
GCAAGCAATAAAAAGTAAAGCTACCAAACATCATCAAATAAAAATGAAGAAGGCATAACC
TCAAGAGGCTCTCCTAATATTTCTTTAGTTGAAAACATTAGCATTTAAGAAAAAAACCCA
ACTTTAAATTCTTAAAATAATAGCTTAGAAGTCATTAGCAACTACATGAAGAAGTTAAAG
ATGCGTCCTCAAAGCTCTGCAATTAGAAATTGTATTACAGTTGAGTGCTAAAACAACTCT
AGCAAATGCAGTAGTATTTTAAATGTAGCTCCTCATCCTTCTCAACAAAATTTAGAAATA
AATTAATAGTAAACTCTAATTACAGAAGAGACATGCCCAAAATTCATTGTTCCTAATGTT
AGATATTCCCAAAATTCTAGTAATATTATCTAAACATAGAGCACTTTTGGGGAAGAGAGT
TTTCTCAATAAAAAGCTAAAAAACGTAAATGGCTATTACAATGATGTGAGAAATTATCGT
ATTCGCTATGCTAGATAAGGATCTAAAGATAATAGGATATAAGCTAGTAATATAAATTCT
AATGTAAATTCCTCTTTCAATAATTATAATAATAATAACAGTTCATTTAACAATAACTAC
AATAGTAATGTAAATAATTCATTTAATAACTATAACTACAATAAAAAAATATTAAAATCT
GAGGAAGACTCTACAAGCTATTCACCATCGGCTTTAGCAAGAGGATTTATTGTTCCTTAT
AGTGCAATTTAGCATGATAAAAATTCTAGAATTAGCACTATTATTTCTTCATCTTCTTAA
TAACCCCGTAGACTTCCTTCTTCTGGTAGAAATAACCAGAAAAAGAGCTATTCACCTATA
AATAAAATAACTTAATTCACTTAATTAATGAAAAGATATTTACCTAAAGGAATGCTCAAA
AACTGTCCAGTTTCAAATCAGGAAAGAAATAATTCTAACAATTCTTCTATCAACTAAAAT
AATCACAGAAGTCCTATAGTATATTAAAAGACCCCTAATTCAGCTAAATATCCTTCTCAT
AAAATAGCAGCTGCAGCAGCTTTTAATACAAGTTTAGTTTCATAGCTAAATAATAGCTCC
ATAAACAGTAACAACTACTCATTTAATAACCAAAATATATCTCCTGTCATCACTTCTAAT
AAAGAAAATGTAAATACAGCAAATATTCTTGACAACAGCTTTGCTTTGATTCGTCATTAA
GCAAGATAAAATATCTATAAAAATAATAATTAGTAAAATGGTGGAGTTAGAGCTGTTTAA
TACGAAAAAAATTTTTTTAATAACAACAACAATAACAATCATTTGAATTGTAACACAAAT
CATATCTAAATAGTTAAAAAACTAGGAAACGTAAATAATGTTTTAAACTCTCATACTTAC
AACATAAATCGCTCATCTCCACCTAAAAAAGCCTAATAAAAAGATTCATAGCATAGAAAA
AATATTTTCTATCACCCAAATTATATAAATTGTTTAAATTAAAATATTAATAGCTCTATT
GTGTAAAAAGTGGCTTATGTGCAAAATCCAAAAAGTTTAAACTCTAAAATTAGCACTTCC
AACAACCAAAGCAGCTCTCAAGAAAGAAAATAAATTAAATAAATCTTGAGGTGA

>TTHERM_01027700(protein)
MDDTISSFGTFASPVKPNSKLNDFKILCKLGEGSFSTVFKVLRLVDNKIYAMKKVQMSRL
NEKEKGNSLNEIRILASIKCDHIIEYRDSFFDDQSDTLCIVMEYAGSGDLLQKLKEYKLI
NEKLLEDGQNETSESQVEQDSSPKEESDKSSRSQEKNKRIYNKLNQQNESIKSKKSSIQE
NSSKSVVQDKQQQMVFMDEELIWDYFIQCLKGLKCLHDLKIVHRDLKCANIFIGDNNIIK
IGDLNVSKVTRRPEQMAKTQTGTPYYTAPEVWKGLSYNYKSDVWSLGCIIYELSAQKHPF
KGNTIEGLFTNIMKGQYERIPSFYSEELAFVISQCLLQNPKLRPGCDQLLKLPAFASRLQ
KYEEKYRQYLQNHNKQKIHSNFLNVTSQNHLEFTPQRVQKTNTEGPHLIDTINMPSNLKQ
LSALLPKSNYEDTPIQLPSISEFDENIVNNNNHLHNKSNFMKLRASVQKVSEFDQLEKIS
SADSSSSSSSPSAATNRITKNFKDNNELQNDQLKTSQMHQDNIFQALLDLQPADILNQKL
TLTQQQKETTKLTNKKMSQLQPYHDLVNDSPIRFNLQKVQMENKNQEQKSDEKKENSERK
NITLQKIDFINEQKNHSGLSQNNNTKNTISTNAQTFKNNDASNKKQSYQTSSNKNEEGIT
SRGSPNISLVENISIQEKNPTLNSQNNSLEVISNYMKKLKMRPQSSAIRNCITVECQNNS
SKCSSILNVAPHPSQQNLEINQQQTLITEETCPKFIVPNVRYSQNSSNIIQTQSTFGEES
FLNKKLKNVNGYYNDVRNYRIRYARQGSKDNRIQASNINSNVNSSFNNYNNNNSSFNNNY
NSNVNNSFNNYNYNKKILKSEEDSTSYSPSALARGFIVPYSAIQHDKNSRISTIISSSSQ
QPRRLPSSGRNNQKKSYSPINKITQFTQLMKRYLPKGMLKNCPVSNQERNNSNNSSINQN
NHRSPIVYQKTPNSAKYPSHKIAAAAAFNTSLVSQLNNSSINSNNYSFNNQNISPVITSN
KENVNTANILDNSFALIRHQARQNIYKNNNQQNGGVRAVQYEKNFFNNNNNNNHLNCNTN
HIQIVKKLGNVNNVLNSHTYNINRSSPPKKAQQKDSQHRKNIFYHPNYINCLNQNINSSI
VQKVAYVQNPKSLNSKISTSNNQSSSQERKQIKQILR

>TTHERM_01027700(gene)
ATGGACGATACAATTTCTTCTTTTGGAACATTTGCTTCTCCAGTCAAGCCAAATTCTAAA
TTAAATGATTTCAAGATTCTATGTAAATTAGGCGAAGGATCATTTTCAACTGTGTTTAAA
GTACTCCGTTTAGTAGATAACAAGATTTATGCCATGAAGAAGGTTTAAATGAGCAGATTA
AATGAAAAGGAAAAAGGAAATTCTTTAAATGAAATAAGAATTTTAGCTTCAATAAAGTGC
GATCATATTATAGAATACAGAGACAGCTTTTTTGATGATTAATCAGACACACTTTGTATA
GTTATGGAGTATGCAGGTAGTGGTGATTTACTTCAAAAATTAAAAGAGTATAAGCTAATA
AATGAAAAATTACTTGAGGATGGATAAAATGAAACAAGTGAGAGCCAGGTAGAACAAGAT
TCATCTCCAAAAGAAGAAAGTGATAAAAGTTCTCGTTCTTAAGAGAAAAACAAGCGCATA
TACAACAAACTCAATTAATAAAATGAAAGTATTAAATCAAAGAAATCATCAATATAAGAA
AACTCAAGTAAGTCTGTGGTGTAAGATAAGCAATAATAGATGGTTTTTATGGATGAAGAG
TTGATTTGGGATTATTTTATTCAATGTTTGAAAGGTTTAAAGTGCTTGCATGACTTGAAA
ATCGTACATCGTGATTTAAAATGTGCAAATATATTTATAGGTGATAATAATATTATTAAA
ATTGGAGATCTAAATGTATCCAAAGTTACAAGAAGGCCAGAGTAAATGGCTAAAACGCAA
ACAGGTACTCCTTATTATACTGCACCTGAAGTGTGGAAAGGGTTGTCTTATAACTATAAA
AGCGATGTTTGGTCTTTGGGATGTATAATATATGAGCTTTCCGCTTAAAAGCATCCTTTT
AAAGGAAATACAATTGAAGGGCTATTTACTAATATAATGAAAGGATAGTATGAAAGAATA
CCAAGTTTTTATTCTGAAGAATTAGCTTTTGTTATATCTTAATGTTTGCTTTAGAATCCC
AAGCTGAGACCAGGATGCGATCAGCTTTTAAAATTGCCTGCATTTGCTTCAAGACTGTAA
AAATATGAAGAAAAGTATAGGTAGTATTTGCAAAATCATAACAAGTAAAAAATTCATTCT
AACTTCCTTAATGTGACATCGTAAAACCATCTTGAGTTTACCCCCTAAAGAGTATAAAAG
ACCAACACTGAAGGACCCCATCTTATCGATACTATTAATATGCCTTCTAACTTAAAATAG
TTGTCTGCTCTCTTACCTAAATCTAACTATGAAGATACCCCAATTTAACTTCCTTCAATA
AGTGAATTTGATGAAAATATTGTTAATAACAATAATCATTTGCACAATAAAAGCAACTTC
ATGAAATTAAGAGCTTCTGTTCAAAAAGTTTCTGAATTTGATTAGCTTGAGAAGATATCT
TCTGCAGATTCTTCATCATCATCTTCCTCACCATCAGCAGCTACAAACAGAATAACCAAG
AATTTCAAGGATAATAATGAACTGTAAAATGATCAATTAAAGACCTCGTAGATGCACCAA
GATAATATATTTTAAGCTTTATTGGACCTTCAACCAGCTGATATTCTTAATCAAAAATTA
ACTTTAACTTAGTAATAAAAGGAAACTACAAAATTAACAAATAAAAAGATGAGTTAGCTC
TAACCTTATCATGATTTAGTCAATGATTCTCCAATACGTTTTAATCTTCAAAAGGTATAG
ATGGAAAACAAAAATTAAGAGCAGAAAAGTGATGAAAAAAAAGAAAATAGCGAAAGAAAG
AATATAACTCTATAGAAAATAGATTTCATTAATGAGCAAAAGAATCACAGTGGCTTGAGT
TAAAATAATAATACTAAAAATACAATAAGTACAAATGCCCAGACTTTCAAAAATAATGAT
GCAAGCAATAAAAAGTAAAGCTACCAAACATCATCAAATAAAAATGAAGAAGGCATAACC
TCAAGAGGCTCTCCTAATATTTCTTTAGTTGAAAACATTAGCATTTAAGAAAAAAACCCA
ACTTTAAATTCTTAAAATAATAGCTTAGAAGTCATTAGCAACTACATGAAGAAGTTAAAG
ATGCGTCCTCAAAGCTCTGCAATTAGAAATTGTATTACAGTTGAGTGCTAAAACAACTCT
AGCAAATGCAGTAGTATTTTAAATGTAGCTCCTCATCCTTCTCAACAAAATTTAGAAATA
AATTAATAGTAAACTCTAATTACAGAAGAGACATGCCCAAAATTCATTGTTCCTAATGTT
AGATATTCCCAAAATTCTAGTAATATTATCTAAACATAGAGCACTTTTGGGGAAGAGAGT
TTTCTCAATAAAAAGCTAAAAAACGTAAATGGCTATTACAATGATGTGAGAAATTATCGT
ATTCGCTATGCTAGATAAGGATCTAAAGATAATAGGATATAAGCTAGTAATATAAATTCT
AATGTAAATTCCTCTTTCAATAATTATAATAATAATAACAGTTCATTTAACAATAACTAC
AATAGTAATGTAAATAATTCATTTAATAACTATAACTACAATAAAAAAATATTAAAATCT
GAGGAAGACTCTACAAGCTATTCACCATCGGCTTTAGCAAGAGGATTTATTGTTCCTTAT
AGTGCAATTTAGCATGATAAAAATTCTAGAATTAGCACTATTATTTCTTCATCTTCTTAA
TAACCCCGTAGACTTCCTTCTTCTGGTAGAAATAACCAGAAAAAGAGCTATTCACCTATA
AATAAAATAACTTAATTCACTTAATTAATGAAAAGATATTTACCTAAAGGAATGCTCAAA
AACTGTCCAGTTTCAAATCAGGAAAGAAATAATTCTAACAATTCTTCTATCAACTAAAAT
AATCACAGAAGTCCTATAGTATATTAAAAGACCCCTAATTCAGCTAAATATCCTTCTCAT
AAAATAGCAGCTGCAGCAGCTTTTAATACAAGTTTAGTTTCATAGCTAAATAATAGCTCC
ATAAACAGTAACAACTACTCATTTAATAACCAAAATATATCTCCTGTCATCACTTCTAAT
AAAGAAAATGTAAATACAGCAAATATTCTTGACAACAGCTTTGCTTTGATTCGTCATTAA
GCAAGATAAAATATCTATAAAAATAATAATTAGTAAAATGGTGGAGTTAGAGCTGTTTAA
TACGAAAAAAATTTTTTTAATAACAACAACAATAACAATCATTTGAATTGTAACACAAAT
CATATCTAAATAGTTAAAAAACTAGGAAACGTAAATAATGTTTTAAACTCTCATACTTAC
AACATAAATCGCTCATCTCCACCTAAAAAAGCCTAATAAAAAGATTCATAGCATAGAAAA
AATATTTTCTATCACCCAAATTATATAAATTGTTTAAATTAAAATATTAATAGCTCTATT
GTGTAAAAAGTGGCTTATGTGCAAAATCCAAAAAGTTTAAACTCTAAAATTAGCACTTCC
AACAACCAAAGCAGCTCTCAAGAAAGAAAATAAATTAAATAAATCTTGAGGTGA