Identifiers and Description

Gene Model Identifier

TTHERM_00947540

Standard Name

NRK7 (NIMA-Related Kinase )

Aliases

PreTt19674 | 174.m00058 | 3678.m00023

Description

NIMA-Related Kinase

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• protein kinase activity (IEA) | GO:0004672
• ATP binding (IEA) | GO:0005524
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) protein kinase domain
• ( PF07714 ) protein tyrosine kinase

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10%

TetraMine Data

TTHERM_00947540

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_19816.1	9.997093137033517e-262	protein kinase domain-containi ng protein (544 aa)
Oxytricha	Contig4483.0.g30	3.9985196551577655e-99	Protein kinase domain
DictyBase	DDB_G0270814	2.0001081030036656e-67	nek2 on chromosome: 1 position 4847143 to 4848761
Stentor Coeruleus	SteCoe_11057	3.392270193026015e-47
WormBase	WBGene00021461	7.00293386439118e-45	locus:nekl-1 status:Partiall y_confirmed UniProt:Q6AW07 protein_id:CCD69902.1
SGD	YAR018C	2.0008536325002377e-42	KIN3 Nonessential serine/threo nine protein kinase; possible role in DNA damage response

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00947540(coding)
ATGAGCAGCTCATCTAGCTAACTGAAAGATTTTGATATTATTAAAACTTTAGGAGAGGGA
TCTTTTGCTAAAGTCTACAAGGTTGTTAGAAAATCAGATGGACAATCTTATGCTATGAAG
AGATGCAAAATAGGATTAATGAAATAAAGAGATAAAGATAATGCTCTCAATGAAGTGCGC
ATATTAGCAAGTATCAAAAATCAATATGTAATTGCTTACAAAGAAGCAATCTACGATGAA
TAGTCTGAATGTCTTTTTGTTATTATGGAATATGCTGCTGGAGGTGATTTACACTAATAA
GTGAAAAGTTGCATTAAATCAAAAACCTACCTTGATGAAAATTAAATATGGATTTGGACA
ATTTAAATGCTATATGGATTGAAAGCTCTCCATGATTTAAAAATTTTACACAGAGACTTA
AAATGTGCTAATATATTTTTAGATAGTAGAAGAAATGCCAAGATTGGAGACTTGAATGTC
TCTAAAATAACTTAGGCAAATTTGGCGAGAACTTAAGTTGGCACTCCTTACTATACTTCA
CCTGAAGTTTGGAAAGACTAAATGTATAACAACAAAAGTGATATCTGGAGTCTTGGATGT
CTTATATATGAACTCTGTGCCCAAAAACCTCCTTTCCTTGCATCTGATATGCCTTCGCTT
TTCAAGAAAATTGGCAAGGGAATTTATGAAAGAATTCCTTCAAGATATTCTAGTGAGTTG
AGTAACCTTATAAGCTAATGTCTTAATATTAATTAGATCACAAGACCTGATTGCGATTAA
CTACTTAATCTACCTATTATAAAGAAAAAAATAGAAGATTTAAATATAAAATTAGAAACC
TTTTCAAAAGAAGACTCTAATGCTCAAGCAATCAACTAAAAATTAAGTGTACTTGATTAA
ATAAAGTTTCCTGCTAATAAGAAAAATCTTTAAGAAAGGTTACCTAAACCTTCGTACAAT
ACTAATAGCTAATAGGAGATAAAAAAATTTACTCCTAATAACTAAATAGGTACTTATCAA
ACACCAACTTCAGAAGAATTGAAAAATATGAGGAGAGTAAGATCTAATTCTGGAATACAA
TTGAAATCTTAAAACTCTTAGCCTCAGCAATATCAAAGATTTGATTTACTGCTTGAATAA
GAAATTCAGAGAAGATTAAATAATCTAAATTCAAGAGAATACTTATCCTAGCAGTCATAA
CAAAATATCCCATCAAGCTCTAATTTGGATTTAAGAAAAAGAAAAATATCTGAAGACTTC
CAAAATTACTAATACAGATAGCTCTTCTAGGATAATCATTACAATCTAAATTATATTAAC
AAACCGACATAATTCGAAAGAAAAAGAAGCGATAGACATTCATATTATGAAAGAAATAGA
GACTAAGAGAATGATATCTAATACAGTAATAGAATTATTCCTCACAGAGATATTTATAGT
GCTAAGAATCCTTTCAGTGGGGATTCTAAAAACGCAAATTAATATATCAAAAAACCTTAC
TCAATTAGAAATGACATTCCTCTTCCATATTCTTCTTTGAATTCTAATAAAGAAGCTTTA
TATTTTGGTGGAGCAAAAAGAGTATAAACAGAAGTTAGATCTCTTCTAAGTAAACAATAT
AGATGA

>TTHERM_00947540(protein)
MSSSSSQLKDFDIIKTLGEGSFAKVYKVVRKSDGQSYAMKRCKIGLMKQRDKDNALNEVR
ILASIKNQYVIAYKEAIYDEQSECLFVIMEYAAGGDLHQQVKSCIKSKTYLDENQIWIWT
IQMLYGLKALHDLKILHRDLKCANIFLDSRRNAKIGDLNVSKITQANLARTQVGTPYYTS
PEVWKDQMYNNKSDIWSLGCLIYELCAQKPPFLASDMPSLFKKIGKGIYERIPSRYSSEL
SNLISQCLNINQITRPDCDQLLNLPIIKKKIEDLNIKLETFSKEDSNAQAINQKLSVLDQ
IKFPANKKNLQERLPKPSYNTNSQQEIKKFTPNNQIGTYQTPTSEELKNMRRVRSNSGIQ
LKSQNSQPQQYQRFDLLLEQEIQRRLNNLNSREYLSQQSQQNIPSSSNLDLRKRKISEDF
QNYQYRQLFQDNHYNLNYINKPTQFERKRSDRHSYYERNRDQENDIQYSNRIIPHRDIYS
AKNPFSGDSKNANQYIKKPYSIRNDIPLPYSSLNSNKEALYFGGAKRVQTEVRSLLSKQY
R

>TTHERM_00947540(gene)
ATGAGCAGCTCATCTAGCTAACTGAAAGATTTTGATATTATTAAAACTTTAGGAGAGGGA
TCTTTTGCTAAAGTCTACAAGGTTGTTAGAAAATCAGATGGACAATCTTATGCTATGAAG
AGATGCAAAATAGGATTAATGAAATAAAGAGATAAAGATAATGCTCTCAATGAAGTGCGC
ATATTAGCAAGTATCAAAAATCAATATGTAATTGCTTACAAAGAAGCAATCTACGATGAA
TAGTCTGAATGTCTTTTTGTTATTATGGAATATGCTGCTGGAGGTGATTTACACTAATAA
GTGAAAAGTTGCATTAAATCAAAAACCTACCTTGATGAAAATTAAATATGGATTTGGACA
ATTTAAATGCTATATGGATTGAAAGCTCTCCATGATTTAAAAATTTTACACAGAGACTTA
AAATGTGCTAATATATTTTTAGATAGTAGAAGAAATGCCAAGATTGGAGACTTGAATGTC
TCTAAAATAACTTAGGCAAATTTGGCGAGAACTTAAGTTGGCACTCCTTACTATACTTCA
CCTGAAGTTTGGAAAGACTAAATGTATAACAACAAAAGTGATATCTGGAGTCTTGGATGT
CTTATATATGAACTCTGTGCCCAAAAACCTCCTTTCCTTGCATCTGATATGCCTTCGCTT
TTCAAGAAAATTGGCAAGGGAATTTATGAAAGAATTCCTTCAAGGTAAATTATTGAAAAT
AAATTATTTCAGTTGCCATAAATTTTTCTAAACTTTAATATTATGAATTCCATCAAAATA
TAATTTTCATAAATCTTCAACATTTAAATCAAAGTATTTAAAGTAGATTATCTTGTTTAA
TGCTTTAATATTTAAATTTTGAATCAATTTTTAATGCATTCATGTTCAGTTAAATGATAG
CAGAGCTAACAATAATTAAATTTATATTTTACTATCAAATTATTTATTTGTCTATTTAAA
AATTTAACATATTTGATTAATTATGTTAAATAAATTTTATTTTCCTAAAATATAGATATT
CTAGTGAGTTGAGTAACCTTATAAGCTAATGTCTTAATATTAATTAGATCACAAGACCTG
ATTGCGATTAACTACTTAATCTACCTATTATAAAGAAAAAAATAGAAGATTTAAATATAA
AATTAGAAACCTTTTCAAAAGAAGACTCTAATGCTCAAGCAATCAACTAAAAATTAAGTG
TACTTGATTAAATAAAGTTTCCTGCTAATAAGAAAAATCTTTAAGAAAGGTTACCTAAAC
CTTCGTACAATACTAATAGCTAATAGGAGATAAAAAAATTTACTCCTAATAACTAAATAG
GTACTTATCAAACACCAACTTCAGAAGAATTGAAAAATATGAGGAGAGTAAGATCTAATT
CTGGAATACAATTGAAATCTTAAAACTCTTAGCCTCAGCAATATCAAAGATTTGATTTAC
TGCTTGAATAAGAAATTCAGAGAAGATTAAATAATCTAAATTCAAGAGAATACTTATCCT
AGCAGTCATAACAAAATATCCCATCAAGCTCTAATTTGGATTTAAGAAAAAGAAAAATAT
CTGAAGACTTCCAAAATTACTAATACAGATAGCTCTTCTAGGATAATCATTACAATCTAA
ATTATATTAACAAACCGACATAATTCGAAAGAAAAAGAAGCGATAGACATTCATATTATG
AAAGAAATAGAGACTAAGAGAATGATATCTAATACAGTAATAGAATTATTCCTCACAGAG
ATATTTATAGTGCTAAGAATCCTTTCAGTGGGGATTCTAAAAACGCAAATTAATATATCA
AAAAACCTTACTCAATTAGAAATGACATTCCTCTTCCATATTCTTCTTTGAATTCTAATA
AAGAAGCTTTATATTTTGGTGGAGCAAAAAGAGTATAAACAGAAGTTAGATCTCTTCTAA
GTAAACAATATAGATGA