Identifiers and Description

Gene Model Identifier

TTHERM_00301840

Standard Name

NRK5 (NIMA-Related Kinase )

Aliases

PreTt19380 | 28.m00339 | 3691.m00156

Description

NIMA-Related Kinase

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein tyrosine kinase activity (IEA) | GO:0004713
• protein kinase activity (IEA) | GO:0004672

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) protein kinase domain
• ( PF07714 ) protein tyrosine kinase

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.1%

TetraMine Data

TTHERM_00301840

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_07713.1	9.997093137033517e-262	protein kinase domain-containi ng protein (906 aa)
Oxytricha	Contig16193.0.g77	3.9998808708412595e-103	Protein kinase domain
DictyBase	DDB_G0270814	1.9999167998962255e-60	nek2 on chromosome: 1 position 4847143 to 4848761
WormBase	WBGene00021461	1.0000844672813518e-48	locus:nekl-1 status:Partiall y_confirmed UniProt:Q6AW07 protein_id:CCD69902.1
Stentor Coeruleus	SteCoe_34862	1.6889118802245324e-48
SGD	YAR018C	8.997207736750494e-46	KIN3 Nonessential serine/threo nine protein kinase; possible role in DNA damage response

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00301840(coding)
ATGGATTTACCAAACATCAATGCAAACAGTGTTTAAGATATTGGATCTCCTTCAAAAAAG
AGAGAAATATCTATAGATGAAACCGGATAGATTGGTTTAAAGAATAAATAAATAGTTTAC
AATTCGAGTAACAATAGCATGAATAAGCGTAAAAGTCCTGATTAAGTTAAAACACCTCCT
CCCCATTAAAATCATAGATCAATTAGCCTGCAACCTAATAATTAATCTGTTTTATAATCC
TCTCCATAGTAGTAATAACAAAATTAAATGGAAAAGAAAAGTAATCCTCTAAGGAGCTCT
TCGATTTTAGATGATTAATTTTTATAGCATGCATCAAATGCCTCAGCTGAAGCTGTTTAA
TAAGTGGTATCAAATTACAGAAATAATCTTATAAATTAATAATCGCAATCTCTGTAGCAG
CCACTTGTAAAGTAACATCCAAAAAATAATTCTAATAACACAAGTAGTTTACAGTAAAGT
CCTTAGCATCACTAAGGTAATACTTATTTCCATGACGAAGAACTCTAAGATTTTGAAATT
CTAAGCAAATTAGGCGAAGGTTCTTTTAGTACTGTGTATAGAGTTAGACGTGGAAAGGAT
GGAAAAGAATATGCTTTGAAAAGAATAAAGATGATGAAATTAAATGAAAAAGAAAGGGAA
AACGCAGTAAATGAAGTGAGATTTTTGGCTTCAATTAACTGCAGGAATATAATCAGCTAC
AAATAAGCTATTTATGATGAAGGAGTCAATCAATTATGTGTTATAATGGAATATGCGGAG
GGAGGCGATTTAGCTAGAATTATTCGTCATGCTTCAAAAGCAGGTAAATATATTGAGGAA
GATATGATTTGGTCATATGCTATTTAAATGACCATAGGCATTAAAGCGTTACATGATTTA
AATATATTGCATAGAGATTTAAAGGCAGCTAATGTTTTCTTAGATAAGTATTAAACAAGG
GCTATGTTGGGAGACTTGAATGTATCAAAAAAACTACAAGTGAACGGTTTACTTTATACT
CAAACTGGTACTCCTTACTATGCCTCTCCAGAAGTTTGGAAAGATAAACCTTACAATAAT
AAAAGTGATATTTGGAGTTTGGGCTGTGTTATATATGAAATGTGTGCTCTGAAACCACCA
TTTAAGGGAAAAGATATGGAAGACTTATTTAAAAAGGTATAAAGAGGTGTCTACGATCCT
ATTCCTTCTCACTTTAGCAAAGAGCTAAACCTCTTCATTGCTTAATTATTAAGGGTAAAC
CCTGAATAGCGTCCTAATTGTGATGAAATTCTCAAATTTTCTGTGATTAAAAAAAGAATG
GCTGATATGCAGCATTTCTTTTCAGATTCTCTTACTCCTTTCTAACAAAAAATGTAATCT
GAATTAATAAGCACAATTCGTATTGGGAAGTCTTTACGTGGGTTAAAAGATAAATTGCCT
CAGGCAAGATACGAAACAACGGAATCTACTTAAGCTACAACAAATTAAATAACTTCTTAG
TCAGAAATTTTACAACCTAATTAATACCACCGTCAAAGAAAAAATAAATACATTTCTCAT
ATATCGTCAAGTAATATAAGTGATATGATGAATTAACAAATAAGCATACCATCTTAACTA
TTAAATCCGTCTGTAGAAATATAAAGTAAAGGCTTGAATGATAATCACAAAGGAAGTTCA
AGTTTGAACTAGAATTCCATTTCTTTAAGATAATCTTAATAACAATAAGTTATCCCTTCT
ATATAATCATCACCTCCATCATAAAAATCTGAACATATTAAATAAATTATTGCATAAAAA
TAATAAAATAAATCTTCATTATATTAAAAATAATATTAATACCCACGGTTGCCACTTTAG
CATTAATAATTTGATAGTGCCTCTCCAATATAAGCTAAAAGCAGATGTAGTTCTGTAGAA
AGTAAGCAATCAATACATAAAAATTAGCTAAGTCTTCATAAGTAATACTACCAAAATAAT
GATATAAATAAATCTATTAATTTGAATAATTCATAAAACTCTATTGTCACAAATAAAAAA
CCGATACGAAACAAAGAAAGTAATACACCATAAATGTACTAATTATAAAAAGCAGAAGAA
CCAATATCAGTCAATTAAAGTGTCCAGTAGCTTTCAAAAGAAATAAAATAATTAAATTCT
AATTTATATAATGATGAGATGAATAGTCGCTAGAAAAAAATGTATCAACTTTAAGCTTTA
TAAAAAATCTTAGATTAAAAATGTTAACTACCTCAAATACTGAAGACATCCATATACTGA

>TTHERM_00301840(protein)
MDLPNINANSVQDIGSPSKKREISIDETGQIGLKNKQIVYNSSNNSMNKRKSPDQVKTPP
PHQNHRSISLQPNNQSVLQSSPQQQQQNQMEKKSNPLRSSSILDDQFLQHASNASAEAVQ
QVVSNYRNNLINQQSQSLQQPLVKQHPKNNSNNTSSLQQSPQHHQGNTYFHDEELQDFEI
LSKLGEGSFSTVYRVRRGKDGKEYALKRIKMMKLNEKERENAVNEVRFLASINCRNIISY
KQAIYDEGVNQLCVIMEYAEGGDLARIIRHASKAGKYIEEDMIWSYAIQMTIGIKALHDL
NILHRDLKAANVFLDKYQTRAMLGDLNVSKKLQVNGLLYTQTGTPYYASPEVWKDKPYNN
KSDIWSLGCVIYEMCALKPPFKGKDMEDLFKKVQRGVYDPIPSHFSKELNLFIAQLLRVN
PEQRPNCDEILKFSVIKKRMADMQHFFSDSLTPFQQKMQSELISTIRIGKSLRGLKDKLP
QARYETTESTQATTNQITSQSEILQPNQYHRQRKNKYISHISSSNISDMMNQQISIPSQL
LNPSVEIQSKGLNDNHKGSSSLNQNSISLRQSQQQQVIPSIQSSPPSQKSEHIKQIIAQK
QQNKSSLYQKQYQYPRLPLQHQQFDSASPIQAKSRCSSVESKQSIHKNQLSLHKQYYQNN
DINKSINLNNSQNSIVTNKKPIRNKESNTPQMYQLQKAEEPISVNQSVQQLSKEIKQLNS
NLYNDEMNSRQKKMYQLQALQKILDQKCQLPQILKTSIY

>TTHERM_00301840(gene)
TCAATAATTTTTTTGGATAGTATAATTAATAAGTAAAATAAATACATAATTTTTTTAGCG
ATTTGTGAATTCTTTCAAATGGATTTACCAAACATCAATGCAAACAGTGTTTAAGATATT
GGATCTCCTTCAAAAAAGAGAGAAATATCTATAGATGAAACCGGATAGATTGGTTTAAAG
AATAAATAAATAGTTTACAATTCGAGTAACAATAGCATGAATAAGCGTAAAAGTCCTGAT
TAAGTTAAAACACCTCCTCCCCATTAAAATCATAGATCAATTAGCCTGCAACCTAATAAT
TAATCTGTTTTATAATCCTCTCCATAGTAGTAATAACAAAATTAAATGGAAAAGAAAAGT
AATCCTCTAAGGAGCTCTTCGATTTTAGATGATTAATTTTTATAGCATGCATCAAATGCC
TCAGCTGAAGCTGTTTAATAAGTGGTATCAAATTACAGAAATAATCTTATAAATTAATAA
TCGCAATCTCTGTAGCAGCCACTTGTAAAGTAACATCCAAAAAATAATTCTAATAACACA
AGTAGTTTACAGTAAAGTCCTTAGCATCACTAAGGTAATACTTATTTCCATGACGAAGAA
CTCTAAGATTTTGAAATTCTAAGCAAATTAGGCGAAGGTTCTTTTAGTACTGTGTATAGA
GTTAGACGTGGAAAGGATGGAAAAGAATATGCTTTGAAAAGAATAAAGATGATGAAATTA
AATGAAAAAGAAAGGGAAAACGCAGTAAATGAAGTGAGATTTTTGGCTTCAATTAACTGC
AGGAATATAATCAGCTACAAATAAGCTATTTATGATGAAGGAGTCAATCAATTATGTGTT
ATAATGGAATATGCGGAGGGAGGCGATTTAGCTAGAATTATTCGTCATGCTTCAAAAGCA
GGTAAATATATTGAGGAAGATATGATTTGGTCATATGCTATTTAAATGACCATAGGCATT
AAAGCGTTACATGATTTAAATATATTGCATAGAGATTTAAAGGCAGCTAATGTTTTCTTA
GATAAGTATTAAACAAGGGCTATGTTGGGAGACTTGAATGTATCAAAAAAACTACAAGTG
AACGGTTTACTTTATACTCAAACTGGTACTCCTTACTATGCCTCTCCAGAAGTTTGGAAA
GATAAACCTTACAATAATAAAAGTGATATTTGGAGTTTGGGCTGTGTTATATATGAAATG
TGTGCTCTGAAACCACCATTTAAGGGAAAAGATATGGAAGACTTATTTAAAAAGGTTAAT
AAAAATAATTTTTAAAATTAACACATTTAATAAGTTTATTGTTGATCTATTCTTATTTAT
GAGCCAAAAACCAAATTAAATTGAATGAAAATAAAAAAAAAGTATATTAAACAAATGATA
AAAATCGAAGAAAAAAATGGTCATATGCAATATCGCATTTCAGCTAAATATAAGCATCAT
TTACAATAAGAAAATATTAAAATTTAATTAATCTAACTAAACAATCTTTTTTTGATCAAA
AAAGCATCTTCTAAGTTTGCTAGTGGGATGAAAATATAGAATACATTAATCAATCTATTA
TCTATGTGATCTATTTGATCTTTAAAAACTTTTAAAGCAAGAAATAAATAAATAAATTAA
GAAAAGAATCGACAAATTTATATTTTGAATTTTTATTTTCATAGCTATTCAATATTTATT
TATTTGATCTACTTCTATAATAATTTATTATAAATATTATAATCAATAGGTATAAAGAGG
TGTCTACGATCCTATTCCTTCTCACTTTAGCAAAGAGCTAAACCTCTTCATTGCTTAATT
ATTAAGGGTAAACCCTGAATAGCGTCCTAATTGTGATGAAATTCTCAAATTTTCTGTGAT
TAAAAAAAGAATGGCTGATATGCAGCATTTCTTTTCAGATTCTCTTACTCCTTTCTAACA
AAAAATGTAATCTGAATTAATAAGCACAATTCGTATTGGGAAGTCTTTACGTGGGTTAAA
AGATAAATTGCCTCAGGCAAGATACGAAACAACGGAATCTACTTAAGCTACAACAAATTA
AATAACTTCTTAGTCAGAAATTTTACAACCTAATTAATACCACCGTCAAAGAAAAAATAA
ATACATTTCTCATATATCGTCAAGTAATATAAGTGATATGATGAATTAACAAATAAGCAT
ACCATCTTAACTATTAAATCCGTCTGTAGAAATATAAAGTAAAGGCTTGAATGATAATCA
CAAAGGAAGTTCAAGTTTGAACTAGAATTCCATTTCTTTAAGATAATCTTAATAACAATA
AGTTATCCCTTCTATATAATCATCACCTCCATCATAAAAATCTGAACATATTAAATAAAT
TATTGCATAAAAATAATAAAATAAATCTTCATTATATTAAAAATAATATTAATACCCACG
GTTGCCACTTTAGCATTAATAATTTGATAGTGCCTCTCCAATATAAGCTAAAAGCAGATG
TAGTTCTGTAGAAAGTAAGCAATCAATACATAAAAATTAGCTAAGTCTTCATAAGTAATA
CTACCAAAATAATGATATAAATAAATCTATTAATTTGAATAATTCATAAAACTCTATTGT
CACAAATAAAAAACCGATACGAAACAAAGAAAGTAATACACCATAAATGTACTAATTATA
AAAAGCAGAAGAACCAATATCAGTCAATTAAAGTGTCCAGTAGCTTTCAAAAGAAATAAA
ATAATTAAATTCTAATTTATATAATGATGAGATGAATAGTCGCTAGAAAAAAATGTATCA
ACTTTAAGCTTTATAAAAAATCTTAGATTAAAGTAAATTTTATTTAATTTTGTTAACAAA
ATAATTTTAATTGATAAAATGTAAATTCTTATTAACTAATAATTTAATATAATCTATTCC
AAAATCAAAAATTTTTTTAACTATTACTAAAATTTTAATATTTTAATTTTTTTTTATTTA
TTTGATGAAGTTTTATAGTATTTAAATAACTTAATATAAGATTTTTATTCTAAAAATTAT
TTTAAATTATAATAGAATGTTAACTACCTCAAATACTGAAGACATCCATATACTGA