Identifiers and Description

Gene Model Identifier

TTHERM_00997660

Standard Name

NRK4 (NIMA-Related Kinase )

Aliases

PreTt24991 | 188.m00067

Description

NIMA-Related Kinase

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein tyrosine kinase activity (IEA) | GO:0004713
• protein kinase activity (IEA) | GO:0004672

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) protein kinase domain
• ( PF07714 ) protein tyrosine kinase

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.9%

TetraMine Data

TTHERM_00997660

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_20932.1	9.997093137033517e-262	protein kinase domain-containi ng protein (552 aa)
Oxytricha	Contig16193.0.g77	6.997863935131626e-107	Protein kinase domain
DictyBase	DDB_G0270814	8.001993295941272e-61	nek2 on chromosome: 1 position 4847143 to 4848761
Stentor Coeruleus	SteCoe_34801	8.408597124803643e-50
SGD	YAR018C	1.000499495426459e-47	KIN3 Nonessential serine/threo nine protein kinase; possible role in DNA damage response
WormBase	WBGene00008956	2.9986404383886433e-43	locus:nekl-3 status:Confirme d UniProt:G5EFM9 protein_i d:CAA92169.2

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00997660(coding)
ATGTCTTTGAATGATTTTGATGTAATTAGGAAATTAGGTGAAGGTGCCTATTCCAGTGTT
TTTAAAGTTCGTAAAATCAGCAATGGTTAAGATTATGCTATGAAAAATATTAAGATGGGA
AGTCTTTCTGCCAAAGAGCAAGAAAACGCTATCAACGAAGTTAGGTTCCTTGCCTCTTTG
AGCTCATAAGAGATCATTGGATATAAAGAAGCATTTTATGATGAAAAGACTGGACTCTTA
CATATAATAATGGAATATTGTGCGGGCGGTGACCTCTTAAACAAGATTCGCAATTTAAAG
AAAAAGAACCAGTATCTTGATGAGAAGGTAGTTTGGCTGTATATAATTTAGATGATTAAA
GGTTTAAAGTGTTTACATGATTTAAATATCTTGCATAGGGATTTTAAGTGTGCCAACATT
ATGCTCACTCGTGATCATAAAAATTTGAAGCTTGGAGATTTAAATGTCTCAAAAGTCGCT
AAGAAAGGGATGCTTTACACTTAGACTGGAACTCCTTATTATGCTTCTCCTGAAGTGTGG
AGAGATAAGCCTTATAATTCAAAATCAGATGTCTGGTCTCTTGGGTGTGTAATCTACGAA
TTGGTTTCTTTAAACCCACCATTCAAGGCTCAAGATATGGAAGGCTTGTTTAAGAAAGTA
CAAAAAGGGTAATATGATCCTATCCCATCTTGGTATTCATAAGATTTAACTGACTTTCTG
AGTTTGTGCTTGTAAGTAAATCCAAAAATGAGATTAACAACTTCAGAATTACTTGAAACA
CCTTACATTTAAAGAAGACTCAACATAGCCTAAGAATTGAATGTTGACTACAATCCTTTT
AATTGTGATGTAAAGTAGGAATTGCTAAAGACTCTGAAGGTAGGGAGGAATCTTAAATAA
CTTAATAACATATTGCCAGAGCCCTAATATGAGTCAACAGCTTCTTCAGAAATGAATTCT
TTTAGCAATGAAGCTAACTCAAAAAATCCAATTTCAACACAAATCAGTGATAGTTAAATT
AACAATTAACTTAATAGCCCACTTAGGCGCAACGAATAACGAAAGCTCAGCTAACCACCA
TCTTAAAAAAATATCTCTCCTGTAATCCCAAAAAAGAGTAGCCATTACAACGGAGTATAT
TCTTAGCATATGATTCCTTCTTCTAGCAATATACCCTCAATCAATTAAATTCAATCAGAA
ATGAATTTAGATGCTTATGAGCAGCGCCACAATCCCCACATCAGCAAAGCTAGCAGAAGT
AGAAGTATTGAAAATTTAATATAAATGAAGCATCCTATGAGTTCTAAAGGTTCTTAATAA
AATCTTTAATTAGGAAATCATCGTTATTAGCAAAGCAAAGATACAATTCCAACTCTCCCA
CCAATAAATGAAAATAAGAGAAATTTAATTAAATCTGTTTAAGATAATATATTAACAAAT
ATCAAACCAGTTAATTATAATAAAAACTATGATCAAGGAAGTAACAATTCATATATATCA
AAAAATTATAGTAACAAGTTAATTAATCCTATCAGTAGCCAAAATAATATAGTAAATGGT
ATTACAACAAGCGCTAACAGCATCTCGAACACAAATCTCTAGAGAGATAATAGTGTACTT
CTTTTTGCTGGTAAAAAGCTCATTTGA

>TTHERM_00997660(protein)
MSLNDFDVIRKLGEGAYSSVFKVRKISNGQDYAMKNIKMGSLSAKEQENAINEVRFLASL
SSQEIIGYKEAFYDEKTGLLHIIMEYCAGGDLLNKIRNLKKKNQYLDEKVVWLYIIQMIK
GLKCLHDLNILHRDFKCANIMLTRDHKNLKLGDLNVSKVAKKGMLYTQTGTPYYASPEVW
RDKPYNSKSDVWSLGCVIYELVSLNPPFKAQDMEGLFKKVQKGQYDPIPSWYSQDLTDFL
SLCLQVNPKMRLTTSELLETPYIQRRLNIAQELNVDYNPFNCDVKQELLKTLKVGRNLKQ
LNNILPEPQYESTASSEMNSFSNEANSKNPISTQISDSQINNQLNSPLRRNEQRKLSQPP
SQKNISPVIPKKSSHYNGVYSQHMIPSSSNIPSINQIQSEMNLDAYEQRHNPHISKASRS
RSIENLIQMKHPMSSKGSQQNLQLGNHRYQQSKDTIPTLPPINENKRNLIKSVQDNILTN
IKPVNYNKNYDQGSNNSYISKNYSNKLINPISSQNNIVNGITTSANSISNTNLQRDNSVL
LFAGKKLI

>TTHERM_00997660(gene)
ATGTCTTTGAATGATTTTGATGTAATTAGGAAATTAGGTGAAGGTGCCTATTCCAGTGTT
TTTAAAGTTCGTAAAATCAGCAATGGTTAAGATTATGCTATGAAAAATATTAAGATGGGA
AGTCTTTCTGCCAAAGAGCAAGAAAACGCTATCAACGAAGTTAGGTTCCTTGCCTCTTTG
AGCTCATAAGAGATCATTGGATATAAAGAAGCATTTTATGATGAAAAGACTGGACTCTTA
CATATAATAATGGAATATTGTGCGGGCGGTGACCTCTTAAACAAGATTCGCAATTTAAAG
AAAAAGAACCAGTATCTTGATGAGAAGGTAGTTTGGCTGTATATAATTTAGATGATTAAA
GGTTTAAAGTGTTTACATGATTTAAATATCTTGCATAGGGATTTTAAGTGTGCCAACATT
ATGCTCACTCGTGATCATAAAAATTTGAAGCTTGGAGATTTAAATGTCTCAAAAGTCGCT
AAGAAAGGGATGCTTTACACTTAGACTGGAACTCCTTATTATGCTTCTCCTGAAGTGTGG
AGAGATAAGCCTTATAATTCAAAATCAGATGTCTGGTCTCTTGGGTGTGTAATCTACGAA
TTGGTTTCTTTAAACCCACCATTCAAGGCTCAAGATATGGAAGGCTTGTTTAAGAAAGTA
CAAAAAGGGTAATATGATCCTATCCCATCTTGGTATTCATAAGATTTAACTGACTTTCTG
AGTTTGTGCTTGTAAGTAAATCCAAAAATGAGATTAACAACTTCAGAATTACTTGAAACA
CCTTACATTTAAAGAAGACTCAACATAGCCTAAGAATTGAATGTTGACTACAATCCTTTT
AATTGTGATGTAAAGTAGGAATTGCTAAAGACTCTGAAGGTAGGGAGGAATCTTAAATAA
CTTAATAACATATTGCCAGAGCCCTAATATGAGTCAACAGCTTCTTCAGAAATGAATTCT
TTTAGCAATGAAGCTAACTCAAAAAATCCAATTTCAACACAAATCAGTGATAGTTAAATT
AACAATTAACTTAATAGCCCACTTAGGCGCAACGAATAACGAAAGCTCAGCTAACCACCA
TCTTAAAAAAATATCTCTCCTGTAATCCCAAAAAAGAGTAGCCATTACAACGGAGTATAT
TCTTAGCATATGATTCCTTCTTCTAGCAATATACCCTCAATCAATTAAATTCAATCAGAA
ATGAATTTAGATGCTTATGAGCAGCGCCACAATCCCCACATCAGCAAAGCTAGCAGAAGT
AGAAGTATTGAAAATTTAATATAAATGAAGCATCCTATGAGTTCTAAAGGTTCTTAATAA
AATCTTTAATTAGGAAATCATCGTTATTAGCAAAGCAAAGATACAATTCCAACTCTCCCA
CCAATAAATGAAAATAAGAGAAATTTAATTAAATCTGTTTAAGATAATATATTAACAAAT
ATCAAACCAGTTAATTATAATAAAAACTATGATCAAGGAAGTAACAATTCATATATATCA
AAAAATTATAGTAACAAGTTAATTAATCCTATCAGTAGCCAAAATAATATAGTAAATGGT
ATTACAACAAGCGCTAACAGCATCTCGAACACAAATCTCTAGAGAGATAATAGTGTACTT
CTTTTTGCTGGTAAAAAGCTCATTTGA