Identifiers and Description

Gene Model Identifier

TTHERM_00809380

Standard Name

NRK31 (NIMA-Related Kinase)

Aliases

PreTt23433 | 137.m00127

Description

Protein kinase domain containing protein. Sequence similarity to the NEK protein kinase family (Eisen et al., 2006)."

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• protein tyrosine kinase activity (IEA) | GO:0004713
• protein kinase activity (IEA) | GO:0004672
• ATP binding (IEA) | GO:0005524

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) protein kinase domain
• ( PF07714 ) protein tyrosine kinase

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.9%

TetraMine Data

TTHERM_00809380

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_01377.1	9.997093137033517e-262	protein kinase domain-containi ng protein (803 aa)
Oxytricha	Contig4483.0.g30	2.000277046697593e-115	Protein kinase domain
DictyBase	DDB_G0275241	1.9992362000979228e-56	nek3 on chromosome: 2 position 4983790 to 4987279
Stentor Coeruleus	SteCoe_11057	3.817497188671175e-54
WormBase	WBGene00008956	1.000159011384939e-43	locus:nekl-3 status:Confirme d UniProt:G5EFM9 protein_i d:CAA92169.2
SGD	YAR018C	3.001129784945559e-41	KIN3 Nonessential serine/threo nine protein kinase; possible role in DNA damage response

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00809380(coding)
ATGAATAAAGACTACTATTAAAATAACAACTACTACAAGTATGGTCACTAGAATAACAAT
TTTAACACCACAATGAGTCAAACGACTCTTAAAGACTTTGAGGTCATATCTAAGTTAGGA
GAAGGTTCTTTTTCATAGGTTTTTTAAGTGAAGAGAAAGTCTGATGGCATGATTTATGCC
ATGAAGAAAGTAAAAATGGGTTTATTGAAAGAAAAGGAAAAAGAAAATGCTCTCAATGAA
GTTCGTATATTAGCTTCATTGAACGACGAATTTATAGTCGGGTATAAAGAAGCATTCATA
GATGAATAGTCCTAAATTCTTTGTGTTGTTATGGAATATGCAGCAGGAGGAGATTTACAA
GGTAAAATCACTGCAAACATCAAAAGCAAGACAATGTTCCCAGAAAGCGAAGTTTGGAAA
GCTTTAATTCATATGTCAAAAGGATTGCAAATTCTTCACTAAATGCAGATTCTTCATAGA
GATCTTAAGTGTGCAAATGTTTTTCTTTCTTTAGAAGGAGTCTACAAGTTAGGTGATTTA
AACGTATCAAAAGTAGCCAAAAAAGGATTAGTTTATACATAAACAGGAACACCATATTAT
GCATCTCCTGAAGTTTGGAGAGACGAACCTTACGATGTCAAAAGCGATATCTGGTCCTTA
GGTTGTGTACTTTACGAAATGTGTGCTCTAAAACCACCTTTTAGGGCTAATGATATGGAA
GGACTATATAAAAAAGTATAAAAAGGAGACTTCGAACGTATACCCAAAAAGTATTCTGAA
GATTTATAGAGAATGTTAACTATGCTTTTGAAAGTGAATCCAAAAGACAGACCAAGCTGT
GAACAAATTCTATCAAATCCTATTGTTTAAAGAAATGGAGGTGAAGATGCATAGTAAAGA
CCACCATCAAATAAAAAATTAGTGAAAAAGTCTTCAAAAGCTGAACTTTTGTAAACAATT
TAACTTCCAAAGAATTTAGGATTACTTAAGGGAAAATTGCCAAAAGCCAATTATAAAAAA
GCTGAGTCAATAGATGATATAGAGCTTGATTATGAGAATGAAGAAAAAGAATAGCTGCAA
CAATAGTTAAAAAAGACAAATAGAATAGTAAGTGCAGGTGTTCGCCGTACAGAAAATTAT
GTCAATAATTTAGGAAATAGAAATAATTTACCTGCTCCTCTAGTTAAATAGCCATCTAGT
AACGAAGTAAAGCATCCTCTTTTAGCAAAAGATATCACGCCATTGTAATAGAAATAATAA
CAATAATATGAAGTACCCAGCAACTACAACCCCTCAAACCTTTCAAATAATGCTTCTAAT
GTTAATTAAAATGGGTAACCCACTGGAATAAAGCCTAGAGTTTTAGGTAGACCTATTAGT
GGTGTTGTATAAACGAAAAATAATATTCCTCCATTGAGTCCTATCCAAGGTCTTGCTAAA
GTAAAGCCTACACTCAGTAGACCAACATCTGGGGCTAGTATAAATTAAATCAATGGAGTA
AATTACAATAAAGACTATAATAGCAACAAAGTTAATGCTGTTAATGAGCCAATAAAACCC
ACTAATCAGTATTATTCTAATTAACCTTAATAAATCGTAAATAGGAATTAAATCAATAAT
GAACCTGTGATAACCAACAACAACCCATACAGGAATGTTGCTGATAGATACGAAATACCC
TCAAGCAATAATAACTACAACAATATAAATAATAATAGATATTCTGCTTTAAATAACAAT
GGCGCTTATTCTAAAAATTTAACTCCTCAGCAGTATTTGATGAAATAACAAAATAACTAC
AATGAACTATATAGCAAATACTAAAACACACCCTCATCAGCAAACGCAAAGTATGAAGAT
TTGAATACAAAATTAGCTATGAAGGAGAAAGCCCTCTTAGGTGGAGGAGGAGGAGTGAGT
TAAAGTCATAATGTGAATGCGATTGCAGATAAATATAGTAATAACAATAACTAATACAAT
ATTCAAAGAATATATTCAGAATAAAATGTCATGAATTATGCAAAACCCTAAAGAATTTAG
TCATCAAAGCCTTATGTAAATAACAACAACAATTACAATTATGACATTTACTAAAAAGAA
AGCAATATTCAATAGCAATATAAATCGCCATAATATGGATAGTACAACAACAATAATAAT
AATAATAATTATAATGTAGCAAGCAATAATAACAACAACATTGTTAATAACAGTAAAGCT
TATGACCCATCTAATTATATGTATGGAAGAAGACAGTAAAGTGCTAATATAATTGCTTAA
GCAAGAAATTAAGTCTATGGAAACTAATAAGCCTATTAAATGCCAATTTAGCCTGTTAAT
AACATTCAACCTGTGAATAGATAAGCACCAGTAAGCAGACCTGTTTGGTGGGGTTGA

>TTHERM_00809380(protein)
MNKDYYQNNNYYKYGHQNNNFNTTMSQTTLKDFEVISKLGEGSFSQVFQVKRKSDGMIYA
MKKVKMGLLKEKEKENALNEVRILASLNDEFIVGYKEAFIDEQSQILCVVMEYAAGGDLQ
GKITANIKSKTMFPESEVWKALIHMSKGLQILHQMQILHRDLKCANVFLSLEGVYKLGDL
NVSKVAKKGLVYTQTGTPYYASPEVWRDEPYDVKSDIWSLGCVLYEMCALKPPFRANDME
GLYKKVQKGDFERIPKKYSEDLQRMLTMLLKVNPKDRPSCEQILSNPIVQRNGGEDAQQR
PPSNKKLVKKSSKAELLQTIQLPKNLGLLKGKLPKANYKKAESIDDIELDYENEEKEQLQ
QQLKKTNRIVSAGVRRTENYVNNLGNRNNLPAPLVKQPSSNEVKHPLLAKDITPLQQKQQ
QQYEVPSNYNPSNLSNNASNVNQNGQPTGIKPRVLGRPISGVVQTKNNIPPLSPIQGLAK
VKPTLSRPTSGASINQINGVNYNKDYNSNKVNAVNEPIKPTNQYYSNQPQQIVNRNQINN
EPVITNNNPYRNVADRYEIPSSNNNYNNINNNRYSALNNNGAYSKNLTPQQYLMKQQNNY
NELYSKYQNTPSSANAKYEDLNTKLAMKEKALLGGGGGVSQSHNVNAIADKYSNNNNQYN
IQRIYSEQNVMNYAKPQRIQSSKPYVNNNNNYNYDIYQKESNIQQQYKSPQYGQYNNNNN
NNNYNVASNNNNNIVNNSKAYDPSNYMYGRRQQSANIIAQARNQVYGNQQAYQMPIQPVN
NIQPVNRQAPVSRPVWWG

>TTHERM_00809380(gene)
ATGAATAAAGACTACTATTAAAATAACAACTACTACAAGTATGGTCACTAGAATAACAAT
TTTAACACCACAATGAGTCAAACGACTCTTAAAGACTTTGAGGTCATATCTAAGTTAGGA
GAAGGTTCTTTTTCATAGGTTTTTTAAGTGAAGAGAAAGTCTGATGGCATGATTTATGCC
ATGAAGAAAGTAAAAATGGGTTTATTGAAAGAAAAGGAAAAAGAAAATGCTCTCAATGAA
GTTCGTATATTAGCTTCATTGAACGACGAATTTATAGTCGGGTATAAAGAAGCATTCATA
GATGAATAGTCCTAAATTCTTTGTGTTGTTATGGAATATGCAGCAGGAGGAGATTTACAA
GGTAAAATCACTGCAAACATCAAAAGCAAGACAATGTTCCCAGAAAGCGAAGTTTGGAAA
GCTTTAATTCATATGTCAAAAGGATTGCAAATTCTTCACTAAATGCAGATTCTTCATAGA
GATCTTAAGTGTGCAAATGTTTTTCTTTCTTTAGAAGGAGTCTACAAGTTAGGTAAAACA
ATAAATAATGCTTAAAATTTATCAAATAAAAGATCCATTACAAACATTTTCTGCAAATAT
ATTTTTGCTTAACTTTAAAAAATACTCATTTTTGTTTATAAAAGACTTGCTTGTTTGTTT
AATAATAAATAATAGACTTAAGAAATTTAAAAATTTGATACAATTTTAAATAGAATTTAA
TCATTTTATTAACATAACAAATAAATAGGTGATTTAAACGTATCAAAAGTAGCCAAAAAA
GGATTAGTTTATACATAAACAGGAACACCATATTATGCATCTCCTGAAGTTTGGAGAGAC
GAACCTTACGATGTCAAAAGCGATATCTGGTCCTTAGGTTGTGTACTTTACGAAATGTGT
GCTCTAAAACCACCTTTTAGGGCTAATGATATGGAAGGACTATATAAAAAAGTATAAAAA
GGAGACTTCGAACGTATACCCAAAAAGTAATAGACAATCATTTATCATTTTTAATTAATA
ATTGAATGAGTTCAAGTTATAAAATTCATAATTCTCTATTTCAGAATGGTTTATTTTAGA
TATTTATTTATTCATAATTTAAATACTTAAACGATATTTAGCTAAATTTTATCGTTAACA
AAAGCAAAAATTATTAAATATTGAGATTTTTAAAAATCCTTAAATAAAAAATAAATAATA
AATTAAATTGAATTGAATGAAAAAAATTTTTTTTAATTTAGAATGAATAAAAAGTTAAAG
TTTTGAATAAATTATTAAAAAAAAAATGAAAACTTTGACATTAAAATAATTTTAAAAATT
TAAATTGAATGCAGGTATTCTGAAGATTTATAGAGAATGTTAACTATGCTTTTGAAAGTG
AATCCAAAAGACAGACCAAGCTGTGAACAAATTCTATCAAATCCTATTGTTTAAAGAAAT
GGAGGTGAAGATGCATAGTAAAGACCACCATCAAATAAAAAATTAGTGAAAAAGTCTTCA
AAAGCTGAACTTTTGTAAACAATTTAACTTCCAAAGAATTTAGGATTACTTAAGGGAAAA
TTGCCAAAAGCCAATTATAAAAAAGCTGAGTCAATAGATGATATAGAGCTTGATTATGAG
AATGAAGAAAAAGAATAGCTGCAACAATAGTTAAAAAAGACAAATAGAATAGTAAGTGCA
GGTGTTCGCCGTACAGAAAATTATGTCAATAATTTAGGAAATAGAAATAATTTACCTGCT
CCTCTAGTTAAATAGCCATCTAGTAACGAAGTAAAGCATCCTCTTTTAGCAAAAGATATC
ACGCCATTGTAATAGAAATAATAACAATAATATGAAGTACCCAGCAACTACAACCCCTCA
AACCTTTCAAATAATGCTTCTAATGTTAATTAAAATGGGTAACCCACTGGAATAAAGCCT
AGAGTTTTAGGTAGACCTATTAGTGGTGTTGTATAAACGAAAAATAATATTCCTCCATTG
AGTCCTATCCAAGGTCTTGCTAAAGTAAAGCCTACACTCAGTAGACCAACATCTGGGGCT
AGTATAAATTAAATCAATGGAGTAAATTACAATAAAGACTATAATAGCAACAAAGTTAAT
GCTGTTAATGAGCCAATAAAACCCACTAATCAGTATTATTCTAATTAACCTTAATAAATC
GTAAATAGGAATTAAATCAATAATGAACCTGTGATAACCAACAACAACCCATACAGGAAT
GTTGCTGATAGATACGAAATACCCTCAAGCAATAATAACTACAACAATATAAATAATAAT
AGATATTCTGCTTTAAATAACAATGGCGCTTATTCTAAAAATTTAACTCCTCAGCAGTAT
TTGATGAAATAACAAAATAACTACAATGAACTATATAGCAAATACTAAAACACACCCTCA
TCAGCAAACGCAAAGTATGAAGATTTGAATACAAAATTAGCTATGAAGGAGAAAGCCCTC
TTAGGTGGAGGAGGAGGAGTGAGTTAAAGTCATAATGTGAATGCGATTGCAGATAAATAT
AGTAATAACAATAACTAATACAATATTCAAAGAATATATTCAGAATAAAATGTCATGAAT
TATGCAAAACCCTAAAGAATTTAGTCATCAAAGCCTTATGTAAATAACAACAACAATTAC
AATTATGACATTTACTAAAAAGAAAGCAATATTCAATAGCAATATAAATCGCCATAATAT
GGATAGTACAACAACAATAATAATAATAATAATTATAATGTAGCAAGCAATAATAACAAC
AACATTGTTAATAACAGTAAAGCTTATGACCCATCTAATTATATGTATGGAAGAAGACAG
TAAAGTGCTAATATAATTGCTTAAGCAAGAAATTAAGTCTATGGAAACTAATAAGCCTAT
TAAATGCCAATTTAGCCTGTTAATAACATTCAACCTGTGAATAGATAAGCACCAGTAAGC
AGACCTGTTTGGTGGGGTTGA