Identifiers and Description

Gene Model Identifier

TTHERM_00188390

Standard Name

NRK28 (NIMA-Related Kinase )

Aliases

PreTt08589 | 15.m00300 | 3697.m00012

Description

NIMA-Related Kinase

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• protein tyrosine kinase activity (IEA) | GO:0004713
• protein kinase activity (IEA) | GO:0004672
• ATP binding (IEA) | GO:0005524

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) protein kinase domain
• ( PF07714 ) protein tyrosine kinase

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 11.7%

TetraMine Data

TTHERM_00188390

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_06354.1	9.997093137033517e-262	protein kinase domain-containi ng protein (711 aa)
Oxytricha	Contig22171.0.0.g21	5.0000898401533074e-117	Protein kinase domain
DictyBase	DDB_G0275241	2.0007889996237956e-71	nek3 on chromosome: 2 position 4983790 to 4987279
WormBase	WBGene00022631	9.996907204735647e-62	locus:nekl-2 status:Confirme d UniProt:O01775 protein_i d:CCD64899.1
Stentor Coeruleus	SteCoe_34837	1.2479464629129513e-47
SGD	YAR018C	1.000159011384939e-43	KIN3 Nonessential serine/threo nine protein kinase; possible role in DNA damage response

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00188390(coding)
ATGAACCCTTATTTAGCCTAGTATTAAGAACTTGAAATTATAGGTCGAGGCAACTTTGGT
TCTGCGACATTAGTTAAAGAAATAGCTACATAGATTCTATTTATTGCTAAAAAAATTATT
TTGGCTGGACTCAAAGAAAGGGAATAGGAATCAGCGAAATAAGAAGCAGAACTTTTAAAA
AGCTTGAAGCATCCAAATATAGTAGCATATAAAGATTCCTTTATGATAGATGGTACTCTT
ATTATTATCATGGAGTATTGTGAAGAGGGTGATATTGCTTTTCACATTAAGCGCAAAAAA
AATAAATAGGAGTATTTTAGCGAGAGAGTAATTCTCAACTGGTTTTTGCAAATAGCTTTC
GCTCTCATATACATCCATGATAAAAAAATATTACATAGAGATATTAAAACTTCCAATATA
TTTGTGACATCAAACGGAACTGTTAAAATTGGAGATTTCGGTATATCAAGAGTACTTGAG
CACACACAAGATTAAGCCTAAACTGTAGTTGGAACACCATACTATATGAGCCCTGAAGTT
TGTGAAAGCAAGCCCTATACTCAAAAATCTGATGTGTGGGCTCTAGGCTGTGTCGTATAC
GAGCTATGCACTTTAAAGCATGCCTTTAACTCAAACAATCTTTTAGGATTAGTATACAAG
ATTGTGAAAGAGTAAGTTGAAGATATTCCTGAAATATATTCAAATGAATTAAAAAATTTA
GTAAAGTAAATGTTTATTAAAGATGATGCATTAAGACCTAATTTGCGCTAAGTTTTAGCA
AGTCCCTTTTTAACTAAAACTATGGAAGAATTTGTGGAAAATTAGGGATAAAACATATAT
TAATCTGAAATTCCAATTCGTAAAACTAATACTCATATGTAAATGCAATAGCAATAGCAA
TATGATGATGGATTAGGTGAAACTGTAAAATCTCAGCAAGCTAATGGTACATAATTTACA
ATAGGTCAAACTATAAATTCAATGTAGCAAACACAACAATAGCGCTATGATTAAACTTTA
GGAGACACTGTTTAATCTGTCAACATTCAAGGTGGAAATTTAACTGCTAAGTAAATGTTG
TAAATCAAAAAGCAATAAGAGAGCGATAAAAAGGCATAAGAGCTGACATAGGCTATAAGA
GAAAATGCATCATTAGTAAATATTGCTAAATAGCGTAAACTAGAATAGCTAAATCATTAA
AACGCAAGAGAAAAGTAAAACATGGCTTAAACTATGTAATAATATTACAGTCAGTAACAA
TAGCCATAATAACAATACTATTCTTCAACCTAAAAATTCTATCCTCAATAAGGATAGTAA
GTACCTATGAATAACTAAAATATGAATATGCTCACTTAGCAAATGGAAATGCTCAGCGTT
TCTTAAAACACAAACTAATTTTATAACTAGCCTTTTGATCATTCCTATCAACCTCAGTAA
ATGTATAACATGCCTATAAATATGAGCCAATAGCAATAATAGAACGAATACAATTATAAC
TAATACAATAACCCTTACAATTAATAATAAGCTATGAATTAGTACTAATAACACAATGAT
CAGACCATAAAAACTGATATTTAAAATGGTAACAAATTCAATGCAACTAATAATGGGTTA
GATGCATATCAAGATGATTTCGAAGAGTATAATAGTGACTAAGAAGATGAAAAAAATAAT
ACCTTCTCATTAACTGCTACATAAAACCGTCTTACTCTAAGAGCTACAGAATCTCAAAGA
GAAGACGTCGTCAACATTTATAAAGATAATCTTAAATTTAAAAACAATGATTTGGAATCT
ATTCATGAATAGTCGGGAGAATATATACCTCAAACACCCCAGAAACAAGGAAAAGGAGAT
GTACCTTATTAAGAAAACAAATCTTTCAACAGTAAAGTAGATAATCTAAGAAAAGAATGC
ATAAATTTATTAACAGAAGAACAATTTAATAAAGTTTATAATTTCATCAAATCTCGCGAT
TACATGAGTAACTAGGACTATTAAGAGTTAAATAAATTAGTTGGAAGAGATATAAAATCT
AAATGCCAAAGGGTAGAAGAGTTAGTTTACTTAGAAAGCATTAGTCATTGA

>TTHERM_00188390(protein)
MNPYLAQYQELEIIGRGNFGSATLVKEIATQILFIAKKIILAGLKEREQESAKQEAELLK
SLKHPNIVAYKDSFMIDGTLIIIMEYCEEGDIAFHIKRKKNKQEYFSERVILNWFLQIAF
ALIYIHDKKILHRDIKTSNIFVTSNGTVKIGDFGISRVLEHTQDQAQTVVGTPYYMSPEV
CESKPYTQKSDVWALGCVVYELCTLKHAFNSNNLLGLVYKIVKEQVEDIPEIYSNELKNL
VKQMFIKDDALRPNLRQVLASPFLTKTMEEFVENQGQNIYQSEIPIRKTNTHMQMQQQQQ
YDDGLGETVKSQQANGTQFTIGQTINSMQQTQQQRYDQTLGDTVQSVNIQGGNLTAKQML
QIKKQQESDKKAQELTQAIRENASLVNIAKQRKLEQLNHQNAREKQNMAQTMQQYYSQQQ
QPQQQYYSSTQKFYPQQGQQVPMNNQNMNMLTQQMEMLSVSQNTNQFYNQPFDHSYQPQQ
MYNMPINMSQQQQQNEYNYNQYNNPYNQQQAMNQYQQHNDQTIKTDIQNGNKFNATNNGL
DAYQDDFEEYNSDQEDEKNNTFSLTATQNRLTLRATESQREDVVNIYKDNLKFKNNDLES
IHEQSGEYIPQTPQKQGKGDVPYQENKSFNSKVDNLRKECINLLTEEQFNKVYNFIKSRD
YMSNQDYQELNKLVGRDIKSKCQRVEELVYLESISH

>TTHERM_00188390(gene)
ATGAACCCTTATTTAGCCTAGTATTAAGAACTTGAAATTATAGGTCGAGGCAACTTTGGT
AAATAAAAATTTGTTTATTAGATTTAGGATAAACCAAGCTTTTAAAAACTAGCTATTACG
TTTATCATTTTAGCTTGATAGATTAGAATCCATATTTAAATATTTATTATATAGGTTCTG
CGACATTAGTTAAAGAAATAGCTACATAGATTCTATTTATTGCTAAAAAAATTATTTTGG
CTGGACTCAAAGAAAGGGAATAGGAATCAGCGAAATAAGAAGTAAAGCCGCTTTAAAAAC
TCTTTATTTATATATTGATTATTCTTGTTATAATTTAGGCAGAACTTTTAAAAAGCTTGA
AGCATCCAAATATAGTAGCATATAAAGATTCCTTTATGATAGATGGTACTCTTATTATTA
TCATGGAGTATTGTGAAGGTAAAAAAAATATTTAAACTCTAAATTAATTTATGAATTTAA
CAATAAAGCTTTCAAATAAATACAAAATAAAAATATTTTTTTATTAATAAATAAATAACT
AATTAAAAGAGGGTGATATTGCTTTTCACATTAAGCGCAAAAAAAATAAATAGGAGTATT
TTAGCGAGAGAGTAATTCTCAACTGGTTTTTGCAAATAGCTTTCGCTCTCATATACATCC
ATGATAAAAAAATATTACATAGAGATATTAAAACTTCCAATATATTTGTGACATCAAACG
GAACTGTTAAAATTGGAGATTTCGGTATATCAAGAGTACTTGAGCACACACAAGATTAAG
CCTAAACTGTAGTTGGAACACCGTAAATATAATTCATAGATAAAAATGAAATTTATTTTT
ATATTAATTAATAGATACTATATGAGGTAGAAAGATTCACAATTTCAATTTTATAACAGC
ATAAATGAAAAAAAGAAATAGAACCATTAAAATATTAATGATTAAGATATGTTTATGCCT
TTAAAATGCATCAGTACTAAACCTAAAATAATAAATAACTCTTATTGCATTATAAATATG
AACAAAAAATTTTTATTTTTTAAAGATAATGAAAATAGATTACTTTAATTTAATTAATTT
TTATCAAATAAAGCCCTGAAGTTTGTGAAAGCAAGCCCTATACTCAAAAATCTGATGTGT
GGGCTCTAGGCTGTGTCGTATACGAGCTATGCACTTTAAAGGTATTTACTAATTAATTAT
TTCTAAAAATAGGCTAAGTAACAATTTATATTTTATATATAGCATGCCTTTAACTCAAAC
AATCTTTTAGGATTAGTATACAAGATTGTGAAAGAGTAAGTTGAAGATATTCCTGAAATA
TATTCAAATGAATTAAAAAATTTAGTAAAGTAAAATTGTTAATTTTTATTGAAAAGATGA
TGATAAAATCTATTAAAACCTTACAAAGTATAAACATTTATTTTATTTATTTATTAAAAG
GTAAATGTTTATTAAAGATGATGCATTAAGACCTAATTTGCGCTAAGTTTTAGCAAGTCC
CTTTTTAACTAAAACTATGGAAGAATTTGTGGAAAATTAGGGATAAAACATATATTAATC
TGAAATTCCAATTCGTAAAACTAATACTCATATGTAAATGCAATAGCAATAGCAATATGA
TGATGGATTAGGTGAAACTGTAAAATCTCAGCAAGCTAATGGTACATAATTTACAATAGG
TCAAACTATAAATTCAATGTAGCAAACACAACAATAGCGCTATGATTAAACTTTAGGAGA
CACTGTTTAATCTGTCAACATTCAAGGTGGAAATTTAACTGCTAAGTAAATGTTGTAAAT
CAAAAAGCAATAAGAGAGCGATAAAAAGGCATAAGAGCTGACATAGGCTATAAGAGAAAA
TGCATCATTAGTAAATATTGCTAAATAGCGTAAACTAGAATAGCTAAATCATTAAAACGC
AAGAGAAAAGTAAAACATGGCTTAAACTATGTAATAATATTACAGTCAGTAACAATAGCC
ATAATAACAATACTATTCTTCAACCTAAAAATTCTATCCTCAATAAGGATAGTAAGTACC
TATGAATAACTAAAATATGAATATGCTCACTTAGCAAATGGAAATGCTCAGCGTTTCTTA
AAACACAAACTAATTTTATAACTAGCCTTTTGATCATTCCTATCAAGTAAATCTAATCAT
TTATTTATTTATTTTTTTTTAGTTTTTATAAAAAGTATTTACTTTTAAAATATTTAAAAA
ATAGCCTCAGTAAATGTATAACATGCCTATAAATATGAGCCAATAGCAATAATAGAACGA
ATACAATTATAACTAATACAATAACCCTTACAATTAATAATAAGCTATGAATTAGTACTA
ATAACACAATGATCAGACCATAAAAACTGATATTTAAAATGGTAACAAATTCAATGCAAC
TAATAATGGGTTAGATGCATATCAAGATGATTTCGAAGAGTATAATAGTGACTAAGAAGA
TGAAAAAAATAATACCTTCTCATTAACTGCTACATAAAACCGTCTTACTCTAAGAGCTAC
AGAATCTCAAAGAGAAGACGTCGTCAACATTTATAAAGATAATCTTAAATTTAAAAACAA
TGATTTGGAATGTAAAATTTTTCTATCTAAATAATATTTTTCTATACAATTAAAATTAAC
TTACACAAAAATAAATAGCTATTCATGAATAGTCGGGAGAATATATACCTCAAACACCCC
AGAAACAAGGAAAAGGAGATGTACCTTATTAAGAAAACAAATCTTTCAACAGTAAAGTAG
ATAATCTAAGAAAAGAATGCATAAATTTATTAACAGAAGAACAATTTAATAAAGTTTATA
ATTTCATCAAATCTCGCGATTACATGAGTAACTAGGTAAGAATCTTTACTTTCGAAATGT
CATGTTTTAATTTTTTTGTTTGTTTTAAAATAGGACTATTAAGAGTTAAATAAATTAGTT
GGAAGAGATATAAAATCTAAATGCCAAAGGGTAGAAGAGTTAGTTTACTTAGAAAGCATT
AGTCATTGA