Identifiers and Description

Gene Model Identifier

TTHERM_00449170

Standard Name

NRK21 (NIMA-Related Kinase)

Aliases

PreTt15435 | 52.m00213 | 3811.m00970

Description

NRK21 Serine/Threonine kinase domain protein; NIMA-Related Kinase

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein tyrosine kinase activity (IEA) | GO:0004713
• protein kinase activity (IEA) | GO:0004672

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.3%

TetraMine Data

TTHERM_00449170

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_14993.1	9.997093137033517e-262	hypothetical protein (2244 aa)
Oxytricha	Contig1219.1.g101	1.0000620911535021e-130	Protein kinase domain
DictyBase	DDB_G0275241	4.000989088096131e-71	nek3 on chromosome: 2 position 4983790 to 4987279
Stentor Coeruleus	SteCoe_32875	1.733141042341547e-58
WormBase	WBGene00022631	6.001055639413166e-58	locus:nekl-2 status:Confirme d UniProt:O01775 protein_i d:CCD64899.1
SGD	YMR001C	4.999456391042964e-45	CDC5 Polo-like kinase with mul tiple functions in mitosis and cytokinesis through substrate phosphorylation, also functio ns in adaptation to DNA damage during meiosis; has similarit y to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substr ate

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00449170(coding)
ATGAGACCAACTTAGGCACCATCAGCAAATCAATAGTAAGCTGCTGAATATGAACTTTAC
AAGAGAATTAAATTGCTAGGTGAAGGAGCCTTTGGTAAGGCTTATTTAGTAGAAGATTTG
CGTACACATGAATTACTGGTTTAGAAGTAGATGGACATGAAGGCAATGTCTACAGAAGAA
AAACGTGAAACATAAAAAGAGGCAAGAATTTTATAGCAATTAAATCACCCTAACATAGTT
AAATTTAAGGACGTTTATACCACCAAGAAGGGAAAGTTATGTATTATTATGGAATATGCA
GATGGTGGTGATTTGGCAAAGGTAGTTAAGGATGCTAGAGGAAAATATCTTTAGGAAAAA
TAAATTTTAGATTGGTTTACTTAAATTTGTTTGGCTATGAAGCACGTTCATGATAGAAAA
ATTATTCATCGTGACTTGAAAGGACAGAATATTTTTTTGACAAGGAACCATATTGTAAAG
CTAGGTGATTTTGGAATAGCAAGAGTTTTGAGTAAGACAGTAGAAAAGGCAAAAACAATG
GTAGGAACGCCCTATTATTTATCGCCTGAAATTATTGAAAGCAAACCATATTCATTCAAG
ACTGATATTTGGTCTTTGGGAGTCATTTTATATGAGCTTTGTGCATTAAAGCCACCTTTT
AATGCTGATTCTTTGCACTTTTTAGCTTTGAAAATTGTTAAAGGTTAATATTCGCCAATT
CCAACTCATTTCTCAAAAGAAATGAAAAACTTAGTATCAAACCTTCTATAAGTTGATGCT
ATTAGAAGACCTTCTATTAATGATATTATGAAAATGCCTATTATTTAAGAGAGAGTTAAA
AATTTCCTTTCTGAAACAATAAGACAAGTTGAATTCTCACACACCATTCTTCATAATAAA
ATAATTGATGCAAAAGTTAATTTGGCTGACATTAAAATGGTAAACTAAGAATAACCTTGT
CCACCTCATTTAATTTAGCAATACATGAATAAAGATTAAAAAGATCAAAATTAATAATAG
AAGCCTTAAAATCCACCTCCTTAGTAGCCACCTCAATAGTAGTAATAAGCTCCTCAGCCT
TAAAAGGGAGCTAATTTCCACTATAAACCATAATAGAACCCTGTATAAAATTATGCAAAT
AATTACAGACCATAGTCTGCAAGAAATGACTAGGTTCAAAATAATAATATTCAATAGCAA
GTTGCTTAAGATTTAGAAAGAAAAAAAGAAATGGAACGTCTGAAATTAGAGAGAGACAGA
TTGGAGTTAGAAAAGAAGAAAGAATAAGAACGCATAAGATAAGAAAAGGAGAAACTAGCA
TATCAAAAGCTAGAATAAGAAAAGGAAGCCCGATATAAGAGATAGAAGGAATAAGAACTT
AAAGAAAAACAAAGAGAAGAGAGAGAAAGAGAACTGCAAAAAATAGCATTTGAAAATAAA
TAGAGACAACTATAGCTAAATCAAATTAATTAAAAACGTGAAGAAGTTTAAGCAGGAGGT
ATGGCTGTTTTTGCAAATCCTAATTTCAAGCCAAATAAGCAGCCAGTAGTGCCTGTAAAA
AATATTTAACTTCCTGCAAGTAAACCATCTTACAATCCCCCAAAAAGTGGTGGAGAGAAA
AGAAATAATAGTAAACCAGCAGTAGCTAGGTCAGGATCTAGCCATAATTAGCAAAATGTT
TCTGATAAAAAAGTAATTCAGCAAAAGAAAGATGAAGAAGCTAAATAGAAAATTATGGAG
CAGAGAATACAAAGATAAAAGTCAGAGAAAGAAAAGAAAGATTATGAAATGAAACTATAA
AAAGAAAAGGAAGAAGAGCTTCTCAAGAAAAAGGAGGATAAACAAAAAAAGATTGATGAA
CAAAGAGAATAAATGATAAAAGACAGAAGAAAATGGTAAAAAGGAGGAGAGAAATAAATC
GAGTTTGTAGAAAATAAAATAGGTGGAAGCACTCCTAGTAGCAATAACTAATTAGAAAAG
GAATCAGATTAGGATAATACTTCAAATGAATAGCTCGAAAAGAAACAAAAAGTACCTGTC
AAAAAGTGGAGCGTGCCTTAAAAGGTAAATAATAAAAAGGACGATTGGGACATTCAAATA
TTTGAATCAAAGAAAAAACCTACTTAAGCAAAATAAAAAAGTGAAGATAAGCTAGATGAA
TACAATAGTGATGAAGAAAATAAATAAGATAAAAAATTATAGAAAAAATAATCAAAAACA
GAAAAAGATTTAGACGAATATAACTCAGATAGCGATGATTTAAATAATAGAAAGGCTGAT
ATTACAGCTCAGGAAATACCAGAAGACATAGAAGAGAACGTTAGCAAACTTCCAGAAATT
GTCAGAGAAGAAACTTACTTATAAAATGAAGATAATACAGAGTTTAATATTGTCAGCGAA
GCTGATCCCAAGTAGTGCTTGGAATTAATGTAATAATTATAAGAAATAGTTGAAAATGCT
GATAAACTTTAAATAGATGAAAAATTTGCAAGAAATGATTTCTTCGATTTCACAAAGACT
TAAAAAACTAAGAAGTTCAATTAACCAAATAAGTCTAAGGAAAGCTTAACGACATAGGAA
GAAGAAGATGAATAAGAAGTCATCAGAGATGATGACTCTGATGAACCTGAACGTCTCTAA
AACACAGGTAAGTTTTTGGATGATTTCCCTGAGCCTCCAAAATTACAGCCTAAATAAATT
GCCCAGGACGAGCAAGAATCAATAAATATAATTGGCAATGGCCACGAAAAGCTAGAACAT
CTTTATATTGAATTAGAGGAAAAATTGTCTGATAATTTTACTAAAGCATACAAAATTATG
AGTGAAGAACTAAAAAAATTAGATTATAATCTAGATCTCTTAGAAAAGAAGTATGGTGAT
AACAGGTACAGCCAGTTGTTAGATTTCCTATCAAAAGATCAAATTGATAAATATTTAAGG
ATCATCATAACTTTAGTTTGTTTAGAATAATAACTTTATAACTCTAATTGA

>TTHERM_00449170(protein)
MRPTQAPSANQQQAAEYELYKRIKLLGEGAFGKAYLVEDLRTHELLVQKQMDMKAMSTEE
KRETQKEARILQQLNHPNIVKFKDVYTTKKGKLCIIMEYADGGDLAKVVKDARGKYLQEK
QILDWFTQICLAMKHVHDRKIIHRDLKGQNIFLTRNHIVKLGDFGIARVLSKTVEKAKTM
VGTPYYLSPEIIESKPYSFKTDIWSLGVILYELCALKPPFNADSLHFLALKIVKGQYSPI
PTHFSKEMKNLVSNLLQVDAIRRPSINDIMKMPIIQERVKNFLSETIRQVEFSHTILHNK
IIDAKVNLADIKMVNQEQPCPPHLIQQYMNKDQKDQNQQQKPQNPPPQQPPQQQQQAPQP
QKGANFHYKPQQNPVQNYANNYRPQSARNDQVQNNNIQQQVAQDLERKKEMERLKLERDR
LELEKKKEQERIRQEKEKLAYQKLEQEKEARYKRQKEQELKEKQREERERELQKIAFENK
QRQLQLNQINQKREEVQAGGMAVFANPNFKPNKQPVVPVKNIQLPASKPSYNPPKSGGEK
RNNSKPAVARSGSSHNQQNVSDKKVIQQKKDEEAKQKIMEQRIQRQKSEKEKKDYEMKLQ
KEKEEELLKKKEDKQKKIDEQREQMIKDRRKWQKGGEKQIEFVENKIGGSTPSSNNQLEK
ESDQDNTSNEQLEKKQKVPVKKWSVPQKVNNKKDDWDIQIFESKKKPTQAKQKSEDKLDE
YNSDEENKQDKKLQKKQSKTEKDLDEYNSDSDDLNNRKADITAQEIPEDIEENVSKLPEI
VREETYLQNEDNTEFNIVSEADPKQCLELMQQLQEIVENADKLQIDEKFARNDFFDFTKT
QKTKKFNQPNKSKESLTTQEEEDEQEVIRDDDSDEPERLQNTGKFLDDFPEPPKLQPKQI
AQDEQESINIIGNGHEKLEHLYIELEEKLSDNFTKAYKIMSEELKKLDYNLDLLEKKYGD
NRYSQLLDFLSKDQIDKYLRIIITLVCLEQQLYNSN

>TTHERM_00449170(gene)
ATGAGACCAACTTAGGCACCATCAGCAAATCAATAGTAAGCTGCTGAATATGAACTTTAC
AAGAGAATTAAATTGCTAGGTGAAGGAGCCTTTGGTAAGGCTTATTTAGTAGAAGATTTG
CGTACACATGAATTACTGGTTTAGAAGTAGATGGACATGAAGGCAATGTCTACAGAAGAA
AAACGTGAAACATAAAAAGAGGCAAGAATTTTATAGCAATTAAATCACCCTAACATAGTT
AAATTTAAGGACGTTTATACCACCAAGAAGGGAAAGTTATGTATTATTATGGAATATGCA
GATGGTAATTTATTTTCTATTTAGTAATATATCAAACAAAATATTAAGCATTTATTTACT
GATAAGAAAGCAAAGTTTGTTTCTAAAATGAGCAATTTTTAAAATATTTTATAGGTGGTG
ATTTGGCAAAGGTAGTTAAGGATGCTAGAGGAAAATATCTTTAGGAAAAATAAATTTTAG
ATTGGTTTACTTAAATTTGTTTGGCTATGAAGCACGTTCATGATAGGTATTTATTTACTT
ATTTTGCATTTCAGGATAACAAAAATAAAATTAAGTTTAAAGAAAGATTATATTTGAACA
GGAATGAATTAATCTTTTAAAAATAGAAAAATTATTCATCGTGACTTGAAAGGACAGAAT
ATTTTTTTGACAAGGAACCATATTGTAAAGCTAGGTGATTTTGGAATAGCAAGAGTTTTG
AGTAAGACAGTAGAAAAGGCAAAAACAATGGTAGGAACGCCCTATTATTTATCGCCTGAA
ATTATTGAAAGCAAACCATATTCATTCAAGACTGATATTTGGTCTTTGGGAGTCATTTTA
TATGAGCTTTGTGCATTAAAGCCACCTTTTAATGCTGATTCTTTGCACTTTTTAGCTTTG
AAAATTGTTAAAGGTTAATATTCGCCAATTCCAACTCATTTCTCAAAAGAAATGAAAAAC
TTAGTATCAAACCTTCTATAAGTTGATGCTATTAGAAGACCTTCTATTAATGATATTATG
AAAATGCCTATTATTTAAGAGAGAGTTAAAAATTTCCTTTCTGAAACAATAAGACAAGTT
GAATTCTCACACACCATTCTTCATAATAAAGTAAATTTAAAATTATAGACGTTTGTTTAA
ATTTTTAACTAGTAAGTAAATGATATTTTGTTAAATTTAAACAGCAATTATGTGTTTGTT
TGCTTATTTTAAATTGAGTATTTAAAATTTTTTCACTTTTCTGATATATTAGAATAAGTA
AATATTTATTTTTATTAAATTTAATTTAGATAATTGATGCAAAAGTTAATTTGGCTGACA
TTAAAATGGTAAACTAAGAATAACCTTGTCCACCTCATTTAATTTAGCAATACATGAATA
AAGATTAAAAAGATCAAAATTAATAATAGAAGCCTTAAAATCCACCTCCTTAGTAGCCAC
CTCAATAGTAGTAATAAGCTCCTCAGCCTTAAAAGGGAGCTAATTTCCACTATAAACCAT
AATAGAACCCTGTATAAAATTATGCAAATAATTACAGACCATAGTCTGCAAGAAATGACT
AGGTTCAAAATAATAATATTCAATAGCAAGTTGCTTAAGATTTAGAAAGAAAAAAAGAAA
TGGAACGTCTGAAATTAGAGAGAGACAGATTGGAGTTAGAAAAGAAGAAAGAATAAGAAC
GCATAAGATAAGAAAAGGAGAAACTAGCATATCAAAAGCTAGAATAAGAAAAGGAAGCCC
GATATAAGAGATAGAAGGAATAAGAACTTAAAGAAAAACAAAGAGAAGAGAGAGAAAGAG
AACTGCAAAAAATAGCATTTGAAAATAAATAGAGACAACTATAGCTAAATCAAATTAATT
AAAAACGTGAAGAAGTTTAAGCAGGAGGTATGGCTGTTTTTGCAAATCCTAATTTCAAGC
CAAATAAGCAGCCAGTAGTGCCTGTAAAAAATATTTAACTTCCTGCAAGTAAACCATCTT
ACAATCCCCCAAAAAGTGGTGGAGAGAAAAGAAATAATAGTAAACCAGCAGTAGCTAGGT
CAGGATCTAGCCATAATTAGCAAAATGTTTCTGATAAAAAAGTAATTCAGCAAAAGAAAG
ATGAAGAAGCTAAATAGAAAATTATGGAGCAGAGAATACAAAGATAAAAGTCAGAGAAAG
AAAAGAAAGATTATGAAATGAAACTATAAAAAGAAAAGGAAGAAGAGCTTCTCAAGAAAA
AGGAGGATAAACAAAAAAAGATTGATGAACAAAGAGAATAAATGATAAAAGACAGAAGAG
TAAATAAATATTAATATTAATTATATTAGTTAAATCATATAAAAAAATAAAGAAATGGTA
AAAAGGAGGAGAGAAATAAATCGAGTTTGTAGAAAATAAAATAGGTGGAAGCACTCCTAG
TAGCAATAACTAATTAGAAAAGGAATCAGATTAGGATAATACTTCAAATGAATAGCTCGA
AAAGAAACAAAAAGTACCTGTCAAAAAGTGGAGCGTGCCTTAAAAGGTAAATAATAAAAA
GGACGATTGGGACATTCAAATATTTGAATCAAAGAAAAAACCTACTTAAGCAAAATAAAA
AAGTGAAGATAAGCTAGATGAATACAATAGTGATGAAGAAAATAAATAAGATAAAAAATT
ATAGAAAAAATAATCAAAAACAGAAAAAGATTTAGACGAATATAACTCAGATAGCGATGA
TTTAAATAATAGAAAGGCTGATATTACAGCTCAGGAAATACCAGAAGACATAGAAGAGAA
CGTTAGCAAACTTCCAGAAATTGTCAGAGAAGAAACTTACTTATAAAATGAAGATAATAC
AGAGTTTAATATTGTCAGCGAAGCTGATCCCAAGTAGTGCTTGGAATTAATGTAATAATT
ATAAGAAATAGTTGAAAATGCTGATAAACTTTAAATAGATGAAAAATTTGCAAGAAATGA
TTTCTTCGATTTCACAAAGACTTAAAAAACTAAGAAGTTCAATTAACCAAATAAGTCTAA
GGAAAGCTTAACGACATAGGAAGAAGAAGATGAATAAGAAGTCATCAGAGATGATGACTC
TGATGAACCTGAACGTCTCTAAAACACAGGTAAGTTTTTGGATGATTTCCCTGAGCCTCC
AAAATTACAGCCTAAATAAATTGCCCAGGACGAGCAAGAATCAATAAATATAATTGGCAA
TGGCCACGAAAAGCTAGAACATCTTTATATTGAATTAGAGGAAAAATTGTCTGATAATTT
TACTAAAGCATACAAAATTATGAGTGAAGAAGTAAGATTTTTTAAACTAGGCAAACAAGT
TACTAAATTTATTTTTTATTCAAGCTAAAAAAATTAGATTATAATCTAGATCTCTTAGAA
AAGAAGTATGGTGATAACAGGTACAGCCAGTTGTTAGATTTCCTATCAAAAGATCAAATT
GATAAATATTTAAGGATCATCATAACTTTAGTTTGTTTAGAATAATAACTTTATAACTCT
AATTGA