Identifiers and Description

Gene Model Identifier

TTHERM_00260770

Standard Name

NRK14 (NIMA-Related Kinase)

Aliases

PreTt29340 | 23.m00236

Description

NIMA-Related Kinase

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein tyrosine kinase activity (IEA) | GO:0004713
• protein kinase activity (IEA) | GO:0004672

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) protein kinase domain
• ( PF04935 ) Surfeit locus protein 6
• ( PF07714 ) protein tyrosine kinase

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.8%

TetraMine Data

TTHERM_00260770

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_13672.1	3.0005221502158484e-68	protein kinase domain-containi ng protein (942 aa)
Oxytricha	Contig6078.0.1.g70	4.00060640795776e-64	Protein kinase domain
DictyBase	DDB_G0289277	1.999534248571833e-46	nek4 on chromosome: 5 position 2561379 to 2563106
WormBase	WBGene00021461	1.9991939848149086e-44	locus:nekl-1 status:Partiall y_confirmed UniProt:Q6AW07 protein_id:CCD69902.1
SGD	YPL203W	2.998863950472602e-38	TPK2 cAMP-dependent protein ki nase catalytic subunit; promot es vegetative growth in respon se to nutrients via the Ras-cA MP signaling pathway; partiall y redundant with Tpk1p and Tpk 3p; localizes to P-bodies duri ng stationary phase
Stentor Coeruleus	SteCoe_30195	2.1705220113036395e-29

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00260770(coding)
ATGTCATCTCAAAATCAATAATCTAATCATTTTAATATACCAGACGGCTATCGATGGATT
AAAAAAATAGGCGAAGGTGCATATGGTTAAGTGCATTTGGTGTAAAGCATTAGAGATGGT
AGTAAATGGGCGATAAAAAATATATATGTTAGTGGAGGTGAAGATGTGAAAAAAAAACGC
TAATCTGAATACAAAATCCTTAAGAAGCTTGATAATCCTCATATAATTAAGTTCAAGGAG
GCTATTAATTATAGAAATTAATAATTGATTTAGATCATTATGGAATACACAGATGGTGGA
GACTTAGAAAAACTAATAGAAAAATAAAAATAAAGTGCAAAACCATTTGAAGAAGAGAAA
ATTTTAGATTTTTTTATTCAAATTTGCTTGGGCTTGGATTGCATACACAAAAATAAAATA
ATTCATAGAGATATCAAACCTGCAAATATATTTTTAACTGCTTTTGGTTAATTGAAAATT
GGTGATTTCGGAGTATCAAAAGAACTTTAATACACTAAATAATGTCTAAAAACAATAGTT
GGGACTCCGTACTATATAGCTCCAGAAATTGTAAGTGGATATGCATATAATTCAAGTGTT
GATATTTGGTCTTTAGGTGTTATTCTATATTAGCTGTGTTGTCTTTAACCACCTTTTTAA
GACTGGAATGAAGCAAATCTTTACTGTAAAATTAAAAAAAAACCCTATCCACCTATAGCT
TAACTTTATTACTCAGGAAAACTTAAAACATTAATATCTAAACTCCTGAGAAAATGCCCA
AAGGAACGCTATACTTTAAAATAAATATTCGACGAATCTTTAATTTAAAGTAGACTCAAA
GTATACTTAAAAAAATCCATTTTAAATAGATCTCCTGATATACCTTAGGTAAATAATTTT
ATGGAGCAAGACTCATTATTGAATCAATTCATATAGAATGATCACTTGTAAGAAAATAGA
TAAGAAATTAACCAATAACCTGTTAATAGCAATGTAAATTAATAAAATATCAATCCAACT
TCTGCTAATAACTAAAATTTCGAAAGTAATAATAATTAATTAAATGAGCTTAGGCCATAA
AGTTGTGCCAATAGGTAAGCTTAAGAAGAATAAAAAAATGAATCTGCTGATAGGAGAAAA
AACTTACAAAAACTTGACAAATAAGAGTAATCAAATTTAGAAGAAAAAAATGCACAGAAT
AATAATAATAATAATAATATAGAAAATAATACAATTCCAGCTAGTCCATAAGTAAAGAAT
TTTAACACTTTAAAAAATGAAAATAACACTCATCTAAGTGGAAAGAGTACTTCATAAAGT
AGTTAAATATCGGACTTAGAAACACCTGTCGCAGAGAAAAAGGTGTAGCATTGTCGATCA
TCAGTTATAATAAAAATTAAAAACATTACTGATTAGAGAAATGAGTAAAATCAAAAAAGT
TAAGATAACCCTTTTATTTTACCAAATCAATAATAAAATAAAAAAGATAATCTTTAGTAG
TTTAAATCAAAATCAGTTATTGTATTCAATGAAAGAGATTTCTTTTGTAATAAATAAATA
TTGCCACCTCTAACATAAATACAAAAAATAGAAATCGAAAAAGAAAATGTAAATCAAAAT
CATTTGAATGAAGATTTATAAAAATAAATTTAAGTAAACAGAAAATATGAAAACATATTT
AGTACACATTAAAAATAAATCAGTGGCTTAGATAAATAAAATATTCAATATGAAAAAAAA
ATAAAATCGAACCTCAATTAGGTTGATAAATTCCCAATAACTCCAACCAAACCAGATTAA
AAAGATTTGAACACAAAATAAAATGGTAATTCTTAAGAACAAAAAAATATTTCTAAAGCA
AAAAGAAATAATTTTAATGAATAAGAATTCAACACTCATTCTTGTTAATTATTGACCGGA
AAAAAAAAAAATTTTGTAGATAAGGAGCAGTCACAAGAGAAGAATTCCAAGGTTCTATTT
GAATAAAAAACTCAAAATATTTGTCTTGAGAAATAATCGTCTAAAAATAACATGATTAGA
GAGCTAAATTAATTTTAAGTACCTTATTCAGAAGATGAATACATCAAATACCTGACGTGT
TTAATTTAAAGTGAACCAAATTATGTCAAAGAAACCTATAATGAGGAAGATTTACTTTAG
GAAAATGATCTTAAACTAATAGATGATGAAGATTTTTATTATGATGATTACTTTGAAGAA
GAAGAAGAAGAAGTAGAAGAAGAAGAAAAAATAAATAAATAACAAGAAAGAGATGTAGAA
AAGATTTATAACATTCCAAGATAATCACAAGAATAATTTAATTAATTGAAGGAAGATTTC
TTTAAAAAAATGACACAAGAGTAATTCAAACTACTTTACAACATAGTAAATAAGGAGATG
TAAAATTAAGACTTCTTAGATGATACACTAAAGAACTAAATAAAGATATTATAAAAAAAG
ATTCTCTCAGTTGAACTAGATGAATTAAAGTATAAAATATAATAATTAATTTATCTATTA
AGTTAAGATTGA

>TTHERM_00260770(protein)
MSSQNQQSNHFNIPDGYRWIKKIGEGAYGQVHLVQSIRDGSKWAIKNIYVSGGEDVKKKR
QSEYKILKKLDNPHIIKFKEAINYRNQQLIQIIMEYTDGGDLEKLIEKQKQSAKPFEEEK
ILDFFIQICLGLDCIHKNKIIHRDIKPANIFLTAFGQLKIGDFGVSKELQYTKQCLKTIV
GTPYYIAPEIVSGYAYNSSVDIWSLGVILYQLCCLQPPFQDWNEANLYCKIKKKPYPPIA
QLYYSGKLKTLISKLLRKCPKERYTLKQIFDESLIQSRLKVYLKKSILNRSPDIPQVNNF
MEQDSLLNQFIQNDHLQENRQEINQQPVNSNVNQQNINPTSANNQNFESNNNQLNELRPQ
SCANRQAQEEQKNESADRRKNLQKLDKQEQSNLEEKNAQNNNNNNNIENNTIPASPQVKN
FNTLKNENNTHLSGKSTSQSSQISDLETPVAEKKVQHCRSSVIIKIKNITDQRNEQNQKS
QDNPFILPNQQQNKKDNLQQFKSKSVIVFNERDFFCNKQILPPLTQIQKIEIEKENVNQN
HLNEDLQKQIQVNRKYENIFSTHQKQISGLDKQNIQYEKKIKSNLNQVDKFPITPTKPDQ
KDLNTKQNGNSQEQKNISKAKRNNFNEQEFNTHSCQLLTGKKKNFVDKEQSQEKNSKVLF
EQKTQNICLEKQSSKNNMIRELNQFQVPYSEDEYIKYLTCLIQSEPNYVKETYNEEDLLQ
ENDLKLIDDEDFYYDDYFEEEEEEVEEEEKINKQQERDVEKIYNIPRQSQEQFNQLKEDF
FKKMTQEQFKLLYNIVNKEMQNQDFLDDTLKNQIKILQKKILSVELDELKYKIQQLIYLL
SQD

>TTHERM_00260770(gene)
ATGTCATCTCAAAATCAATAATCTAATCATTTTAATATACCAGACGGCTATCGATGGATT
AAAAAAATAGGCGAAGGTGCATATGGTTAAGTGCATTTGGTGTAAAGCATTAGAGATGGT
AGTAAATGGGCGATAAAAAATATATATGTTAGTGGAGGTGAAGATGTGAAAAAAAAACGC
TAATCTGAATACAAAATCCTTAAGAAGCTTGATAATCCTCATATAATTAAGTTCAAGGAG
GCTATTAATTATAGAAATTAATAATTGATTTAGATCATTATGGAATACACAGATGGTAAA
TATTTAAAAATGTTATCTTGAAATGAAAGATATTTATTTCTTTTTTGCTTTTTTTATTAG
CTTATTTTTTAGATAATCTATAAAAACAAACCTCAATATTTAATTTATGTAATATTTGCA
ATCAAATATATAAAAAAATTAATAAATAAATATATAGGTGGAGACTTAGAAAAACTAATA
GAAAAATAAAAATAAAGTGCAAAACCATTTGAAGAAGAGAAAATTTTAGATTTTTTTATT
CAAATTTGCTTGGGCTTGGATTGCATACACAAAAAGTAAGTAGAAGAAATAAAATTATAG
TTTTATTTATTAAATAATCTTTTATAATAAAGTAAAATAATTCATAGAGATATCAAACCT
GCAAATATATTTTTAACTGCTTTTGGTTAATTGAAAATTGGTGATTTCGGAGTATCAAAA
GAACTTTAATACACTAAATAATGTCTAAAAACAATAGTTGGGACTCCGTACTATATAGCT
CCAGAAATTGTAAGTGGATATGCATATAATTCAAGTGTTGATATTTGGTCTTTAGGTGTT
ATTCTATATTAGCTGTGTTGTCTTTAACCACCTTTTTAAGACTGGAATGAAGCAAATCTT
TACTGTAAAATTAAAAAAAAACCCTATCCACCTATAGCTTAACTTTATTACTCAGGAAAA
CTTAAAACATTAATATCTAAACTCCTGAGAAAATGCCCAAAGGAACGCTATACTTTAAAA
TAAATATTCGACGAATCTTTAATTTAAAGTAGACTCAAAGTATACTTAAAAAAATCCATT
TTAGTAAATTAATATAAATTTTATTTATTAATTTTTAAGATATAATTTTTTTTTTCTTAT
TAATTTATAGAATAGATCTCCTGATATACCTTAGGTAAATAATTTTATGGAGCAAGACTC
ATTATTGAATCAATTCATATAGAATGATCACTTGTAAGAAAATAGATAAGAAATTAACCA
ATAACCTGTTAATAGCAATGTAAATTAATAAAATATCAATCCAACTTCTGCTAATAACTA
AAATTTCGAAAGTAATAATAATTAATTAAATGAGCTTAGGCCATAAAGTTGTGCCAATAG
GTAAGCTTAAGAAGAATAAAAAAATGAATCTGCTGATAGGAGAAAAAACTTACAAAAACT
TGACAAATAAGAGTAATCAAATTTAGAAGAAAAAAATGCACAGAATAATAATAATAATAA
TAATATAGAAAATAATACAATTCCAGCTAGTCCATAAGTAAAGAATTTTAACACTTTAAA
AAATGAAAATAACACTCATCTAAGTGGAAAGAGTACTTCATAAAGTAGTTAAATATCGGA
CTTAGAAACACCTGTCGCAGAGAAAAAGGTGTAGCATTGTCGATCATCAGTTATAATAAA
AATTAAAAACATTACTGATTAGAGAAATGAGTAAAATCAAAAAAGTTAAGATAACCCTTT
TATTTTACCAAATCAATAATAAAATAAAAAAGATAATCTTTAGTAGTTTAAATCAAAATC
AGTTATTGTATTCAATGAAAGAGATTTCTTTTGTAATAAATAAATATTGCCACCTCTAAC
ATAAATACAAAAAATAGAAATCGAAAAAGAAAATGTAAATCAAAATCATTTGAATGAAGA
TTTATAAAAATAAATTTAAGTAAACAGAAAATATGAAAACATATTTAGTACACATTAAAA
ATAAATCAGTGGCTTAGATAAATAAAATATTCAATATGAAAAAAAAATAAAATCGAACCT
CAATTAGGTTGATAAATTCCCAATAACTCCAACCAAACCAGATTAAAAAGATTTGAACAC
AAAATAAAATGGTAATTCTTAAGAACAAAAAAATATTTCTAAAGCAAAAAGAAATAATTT
TAATGAATAAGAATTCAACACTCATTCTTGTTAATTATTGACCGGAAAAAAAAAAAATTT
TGTAGAGTAAATTAATTGTGATGAAAGTTATTAAAATAATTTATTTTATCATAAAGTAAG
GAGCAGTCACAAGAGAAGAATTCCAAGGTTCTATTTGAATAAAAAACTCAAAGTAAATTA
AATTAAAAATATATTTTTTGAATTTAGTTTTTGTATATGAAGAAGATATTTGTCTTGAGA
AATAATCGTCTAAAAATAACATGATTAGAGAGCTAAATTAATTTTAAGTACCTTATTCAG
AAGATGAATACATCAAATACCTGACGTGTTTAGTATATTAAATTGTTTTAAAATAGCATT
TTGAAATAAACCATTGAATTTTATTTAGATTTAAAGTGAACCAAATTATGTCAAAGAAAC
CTATAATGAGGAAGATTTACTTTAGGAAAATGATCTTAAACTAATAGATGATGAAGATTT
TTATTATGATGATTACTTTGAAGAAGAAGAAGAAGAAGTAGAAGAAGAAGAAAAAATAAA
TAAATAACAAGAAAGAGATGTAGAAAAGATTTATAACATTCCAAGATAATCACAAGAATA
ATTTAATGTAGTTTTCATCAAAATTCCAATTTATATTTATTTATGTCCTATTCATAAATA
TAGTAATTGAAGGAAGATTTCTTTAAAAAAATGACACAAGAGTAATTCAAACTACTTTAC
AACATAGTAAATAAGGAGGTAAAATTAATTTAAAAATATTTTTAAAAGAAGAAAGTAATT
TTATTTTAAAAATTAGATGTAAAATTAAGACTTCTTAGATGATACACTAAAGAACTAAAT
AAAGATATTATAAAAAAAGATTCTCTCAGTTGAACTAGATGAATTAAAGTATAAAATATA
ATAATTAATTTATCTATTAAGTTAAGATTGA