Identifiers and Description

Gene Model Identifier

TTHERM_00657380

Standard Name

NRK10 (NIMA-Related Kinase )

Aliases

PreTt02122 | 97.m00108 | 3724.m00016

Description

NIMA-Related Kinase

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein tyrosine kinase activity (IEA) | GO:0004713
• protein kinase activity (IEA) | GO:0004672

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) protein kinase domain
• ( PF07714 ) protein tyrosine kinase
• ( PF02189 ) Immunoreceptor tyrosine-based activation motif
• ( PF03011 ) Plasmodium falciparum erythrocyte membrane protein

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.2%

TetraMine Data

TTHERM_00657380

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_16251.1	9.997093137033517e-262	protein kinase domain-containi ng protein (930 aa)
Oxytricha	Contig22041.0.g31	1.0000943968537097e-101	Protein kinase domain
DictyBase	DDB_G0275241	1.9997677415930956e-65	nek3 on chromosome: 2 position 4983790 to 4987279
WormBase	WBGene00022631	4.001202823045957e-54	locus:nekl-2 status:Confirme d UniProt:O01775 protein_i d:CCD64899.1
SGD	YAR018C	2.9986404383886433e-43	KIN3 Nonessential serine/threo nine protein kinase; possible role in DNA damage response
Stentor Coeruleus	SteCoe_4747	3.0144087850653746e-40

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00657380(coding)
ATGAAAAGAGGTCTTAGCCCTTCAGTTTCTAAGAATTTAAATTAGGTATAGAATAGTAAA
CCTTATCAATCTTAGGCTGCATAAGTAGTAAAAAAATAGAGCGAATATAAAAATAAATAT
AGAGAGCTAGAGCAAATAGGTAAAGGTACATCAGGAACAGTATTTTTAGTGAAATCTAAA
TAGGATAAAAAATTTTATATTGCAAAGAAAATTATTTTGACAAACTTAAATGAACAGGAA
AGATAAGCAGTAGAATAAGAATTAATCTTACTCAAGAAATTGAAGCACCCTCATATTGTT
GGATATAAGGAAAATTTCTTAGAACCTTACTATATGATTATCATTATGGAATATTGTGAG
TAAGGAGATCTTTCGTTTCATATAAAGCAAAAGCTTAAAGAAAATGATCACTTTCCTGAA
AATATCATTTTAAATTGGTTTATTTAACTAACAATGGCACTTGATTTCATTCATGAAAAG
CATGTTTTGCACAGAGATGTTAAAAGTTCAAATATATTTTTAACTTCTAGTGGTAGCATA
AAGTTAGGAGACTTCGGTATCTCTAAGGTGCTACACTCTACAGCAGATAAAGCTTAAACG
TTAATTGGAACTCCTTATTATTTATCTCCAGAAGTTTGCGAAAACAAACCTTATACTTAT
TAATCAGATATTTGGGCTTTAGGATGCGTGCTTTTTGAAATGTGTGCTTTGAAACACCCT
TTCGTCTCAGAAAGTCTGATGGCCCTAGTTGTAAAAATTATTAGAGAACCAAACCCAAAC
ATTCCTAATATGTATTCAAGCGATCTAAATTGTTTGGTTTAAATTTTATTAGCAAAAAAA
CCAGAAAGTAGACCAAGGACAAAATAAATATTATCATTTCCTTTTGTGAATGAAGCTATG
AAAGATTTTATATCTTCTAAAGGATTAAAAGACGAACTAAAAAATTTGCCAATTAAAAAA
ACTCAGTTGCACATAAAAAAGGAGTAGAAAATAAATTAGGAAAAAGAATAATAACCAAGC
TCAATAAAATAAATTTAAAGGAAAAACAGTTTGTAAAATTAAGCTCAAAAATAGGCAAAT
ATAAAAGCTTAGCCTTAACAAAATGTTTAGAAACATTAAGAGTAATAAAAATCTGTAGGT
AGCACAAAAATTAATAGAAAAAATAGCAATGATATTAAAAAGATGGAGGAACTCATATAA
AAGTAAATGAAAGAAGTTTAAAGCGAAGTATAAAAGAAATTAGTTGAAATTAAAGGCAGT
AATAATAAAAAGCCAAACACCTCTAATCTTTAAGATTAAAAATCACCAAGTAATCCATCA
CTTTCAAAACCATCTTCAGCTTCTTCACAGTCAAGTACAGCTCATTAAACACCATAAAGA
TAAAATGATTAAAAAATAAAGTAATCACCTTCTCGATAAATACAACCCAAGATTGAAGAA
AAGCATACAAAATAATCACCATAGATTATGACAAAAAACAAAGTTGAAACACATAATAAA
TAGTCACCTTAAAGTTAAATAGCATAAAAGTAGGTAGGAACTCCGTAAAATATATCAAAA
AATCCTTCTTCAGGAGTGTTAAGTAATGAAAGTAAAACAAGTAACAGCAGTAAAAACTCA
TCAAGAGTAATTGATGAAGATGATTATGATAAGAAGTATCAGGAAATGATGAATAAAGTT
AAATAGGAGTATGAATAAATAAAAAAAGAGTCTCCAAACCCAAAAAAAAGTCCAACTATA
AATAATTAAAAAGTAGCTTCTAGCTCTTCTGCCTCTTAAAATAATTAAAAATAAAATAAT
TTGATCCATCCTTAAAAAGCTTCCTCAAATTAAAATTATCAACCAACACCAACTTAGCTA
AATCAAGGGGTTGTTAGTGCTTAAAGCTAATAAAGGTATAATACTAACTATTCTAAAAAT
AATTTTGAAATGACCCAAATAGAAGAAGACATTTAGATAAAAAATATTCCTGATAATTAG
GCAGAAAAGGTACAAACTAACATAAATTTGTAAGATAGTTCAAAAAAATAAAATTTTCAT
TTCAGCTAAAAAGGATAAAATAACTCTCTTCTATAAGATTCAAACGTGTCCTTTAATCTC
TCACTAACTAATGATTCTGTTTTTAATAACACTGCATTTAAAAGTAACTTGCCCAAGAAA
TAAAGCACAATTATAACAAGTGGAGGTAAAGAACAAATTATCGAAGAAATAATAGAAAAT
GAAGAAGCATAAGAACATGAAAATATAAAATCTTAAGCTCCAAGCGATGTCAGTGAGTAT
AAAAATGAATTCTTGAATAGTGAGTTTATAAAATCAAATAAAAGTGACGATGCATCTAAA
TATTAGACTGTAATCAGTGAGCACATTTAAACTTAAATGATGCCTTAGATTCCAACTTAA
AATATATAAAAAAACAATTAAGAAGAAATAAATGATTTCTAAGATGATGATTTAGATTTT
GAGTCGCTTCCTCAAAGAGAAGATTATTTAGATTCTGAAGAAGATAATGAGTATGAAGAA
GACTTTGAAGTTAGTTCAGAAGAAGGAGATTCTAAAAATGAATAGAAAGAAAATAATGAT
TTTAGATTGACAAGAAAAAATTTAGACAAAGAACTTGATGAAGTGATCGAAATGTACAAG
TCATAATTGCTTAATAACTCAGGGCAAGAGGAATACAATAAATTTAAGCATATGTTAAAT
ATGTCTGAAATTGCTGAAGCCTCAGTTGAATATTCATCTGGAGAAGTTTCTAAAAAAATG
ATGATACCAGCTGCTTAAAAATAATAGAAATCAAATTTCACAAAAAAGTGA

>TTHERM_00657380(protein)
MKRGLSPSVSKNLNQVQNSKPYQSQAAQVVKKQSEYKNKYRELEQIGKGTSGTVFLVKSK
QDKKFYIAKKIILTNLNEQERQAVEQELILLKKLKHPHIVGYKENFLEPYYMIIIMEYCE
QGDLSFHIKQKLKENDHFPENIILNWFIQLTMALDFIHEKHVLHRDVKSSNIFLTSSGSI
KLGDFGISKVLHSTADKAQTLIGTPYYLSPEVCENKPYTYQSDIWALGCVLFEMCALKHP
FVSESLMALVVKIIREPNPNIPNMYSSDLNCLVQILLAKKPESRPRTKQILSFPFVNEAM
KDFISSKGLKDELKNLPIKKTQLHIKKEQKINQEKEQQPSSIKQIQRKNSLQNQAQKQAN
IKAQPQQNVQKHQEQQKSVGSTKINRKNSNDIKKMEELIQKQMKEVQSEVQKKLVEIKGS
NNKKPNTSNLQDQKSPSNPSLSKPSSASSQSSTAHQTPQRQNDQKIKQSPSRQIQPKIEE
KHTKQSPQIMTKNKVETHNKQSPQSQIAQKQVGTPQNISKNPSSGVLSNESKTSNSSKNS
SRVIDEDDYDKKYQEMMNKVKQEYEQIKKESPNPKKSPTINNQKVASSSSASQNNQKQNN
LIHPQKASSNQNYQPTPTQLNQGVVSAQSQQRYNTNYSKNNFEMTQIEEDIQIKNIPDNQ
AEKVQTNINLQDSSKKQNFHFSQKGQNNSLLQDSNVSFNLSLTNDSVFNNTAFKSNLPKK
QSTIITSGGKEQIIEEIIENEEAQEHENIKSQAPSDVSEYKNEFLNSEFIKSNKSDDASK
YQTVISEHIQTQMMPQIPTQNIQKNNQEEINDFQDDDLDFESLPQREDYLDSEEDNEYEE
DFEVSSEEGDSKNEQKENNDFRLTRKNLDKELDEVIEMYKSQLLNNSGQEEYNKFKHMLN
MSEIAEASVEYSSGEVSKKMMIPAAQKQQKSNFTKK

>TTHERM_00657380(gene)
ATGAAAAGAGGTCTTAGCCCTTCAGTTTCTAAGAATTTAAATTAGGTATAGAATAGTAAA
CCTTATCAATCTTAGGCTGCATAAGTAGTAAAAAAATAGAGCGAATATAAAAATAAATAT
AGAGAGCTAGAGCAAATAGGTAAAGGTACATCAGGAACAGTATTTTTAGTGAAATCTAAA
TAGGATAAAAAATTTTATATTGCAAAGAAAATTATTTTGACAAACTTAAATGAACAGGAA
AGATAAGCAGTAGAATAAGAAGTAATTTATATGCAAATATCTACAATTATTTTATTTAAA
ATAAAATTATTTATTTCAAAGATTCACCAATTTACTTAAAATATTTATCAATTATTTTTT
AATTAGTTAATCTTACTCAAGAAATTGAAGCACCCTCATATTGTTGGATATAAGGAAAAT
TTCTTAGAACCTTACTATATGATTATCATTATGGAATATTGTGAGTAAGGAGATCTTTCG
TTTCATATAAAGCAAAAGCTTAAAGAAAATGATCACTTTCCTGAAAATATCATTTTAAAT
TGGTTTATTTAACTAACAATGGCACTTGATTTCATTCATGAAAAGCATGTTTTGCACAGA
GATGTTAAAAGTTCAAATATATTTTTAACTTCTAGTGGTAGCATAAAGTTAGGAGACTTC
GGTATCTCTAAGGTGCTACACTCTACAGCAGATAAAGCTTAAACGTTAATTGGAACTCCT
TATTATTTATCTCCAGAAGTTTGCGAAAACAAACCTTATACTTATTAATCAGATATTTGG
GCTTTAGGATGCGTGCTTTTTGAAATGTGTGCTTTGAAAGTAATTCTATATTTTAATATA
ACTTTTTAGATTCTACTTATGAATTCATTTAATAAATTTTAAATATTGATAATTAATTTA
CTGAAGTATTTTTGAACTTTATTCTATTTTAAATATTAAAGCACCCTTTCGTCTCAGAAA
GTCTGATGGCCCTAGTTGTAAAAATTATTAGAGAACCAAACCCAAACATTCCTAATATGT
ATTCAAGCGATCTAAATTGTTTGGTTTAGTACAATATTATTAAGATTTTAGATTTATTAA
ATATTTTAATTATTAATAAATAAATAGAATTTTATTAGCAAAAAAACCAGAAAGTAGACC
AAGGACAAAATAAATATTATCATTTCCTTTTGTGAATGAAGCTATGAAAGATTTTATATC
TTCTAAAGGATTAAAAGACGAACTAAAAAATTTGCCAATTAAAAAAACTCAGTTGCACAT
AAAAAAGGAGTAGAAAATAAATTAGGAAAAAGAATAATAACCAAGCTCAATAAAATAAAT
TTAAAGGAAAAACAGTTTGTAAAATTAAGCTCAAAAATAGGCAAATATAAAAGCTTAGCC
TTAACAAAATGTTTAGAAACATTAAGAGTAATAAAAATCTGTAGGTAGCACAAAAATTAA
TAGAAAAAATAGCAATGATATTAAAAAGATGGAGGAACTCATATAAAAGTAAATGAAAGA
AGTTTAAAGCGAAGTATAAAAGAAATTAGTTGAAATTAAAGGCAGTAATAATAAAAAGCC
AAACACCTCTAATCTTTAAGATTAAAAATCACCAAGTAATCCATCACTTTCAAAACCATC
TTCAGCTTCTTCACAGTCAAGTACAGCTCATTAAACACCATAAAGATAAAATGATTAAAA
AATAAAGTAATCACCTTCTCGATAAATACAACCCAAGATTGAAGAAAAGCATACAAAATA
ATCACCATAGATTATGACAAAAAACAAAGTTGAAACACATAATAAATAGTCACCTTAAAG
TTAAATAGCATAAAAGTAGGTAGGAACTCCGTAAAATATATCAAAAAATCCTTCTTCAGG
AGTGTTAAGTAATGAAAGTAAAACAAGTAACAGCAGTAAAAACTCATCAAGAGTAATTGA
TGAAGATGATTATGATAAGAAGTATCAGGAAATGATGAATAAAGTTAAATAGGAGTATGA
ATAAATAAAAAAAGAGTCTCCAAACCCAAAAAAAAGTCCAACTATAAATAATTAAAAAGT
AGCTTCTAGCTCTTCTGCCTCTTAAAATAATTAAAAATAAAATAATTTGATCCATCCTTA
AAAAGCTTCCTCAAATTAAAATTATCAACCAACACCAACTTAGCTAAATCAAGGGGTTGT
TAGTGCTTAAAGCTAATAAAGGTATAATACTAACTATTCTAAAAATAATTTTGAAATGAC
CCAAATAGAAGAAGACATTTAGATAAAAAATATTCCTGATAATTAGGCAGAAAAGGTACA
AACTAACATAAATTTGTAAGATAGTTCAAAAAAATAAAATTTTCATTTCAGCTAAAAAGG
ATAAAATAACTCTCTTCTATAAGATTCAAACGTGTCCTTTAATCTCTCACTAACTAATGT
AATTTTTGATATTTTAACAAATTGTTTGAGCTACTTTAATTTTTTTTTCTCTTTCGTTAA
ACAAAATTAAATTCAATAAAATTGTTTAAATAATAATTTTATTTTATTGAATAATTCAGA
GTTTATTATTTAATTTATAGTTAAGTTAATTAATGATCAAAAATAATTATTTATAAATAA
CAAAATAATTTATTTATTTATTTGCATAATAGGATTCTGTTTTTAATAACACTGCATTTA
AAAGTAACTTGCCCAAGAAATAAAGCACAATTATAACAAGTGGAGGTAAAGAACAAATTA
TCGAAGAAATAATAGAAAATGAAGAAGCATAAGAACATGAAAATATAAAATCTTAAGCTC
CAAGCGATGTCAGTGAGTATAAAAATGAATTCTTGAATAGTGAGTTTATAAAATCAAATA
AAAGTGACGATGCATCTAAATATTAGACTGTAATCAGTGAGCACATTTAAACTTAAATGA
TGCCTTAGATTCCAACTTAAAATATATAAAAAAACAATTAAGAAGAAATAAATGATTTCT
AAGATGATGATTTAGATTTTGAGTCGCTTCCTCAAAGAGAAGATTATTTAGATTCTGAAG
AAGATAATGAGTATGAAGAAGACTTTGAAGTTAGTTCAGAAGAAGGAGATTCTAAAAATG
AATAGAAAGAAAATGTATTTAAAGAGTCTTTTTTGAGTTTTTGATTGACTTTTTTTATTA
ATAAAATAGAATGATTTTAGATTGACAAGAAAAAATTTAGACAAAGAACTTGATGAAGTG
ATCGAAATGTACAAGTCATAATTGCTTAATAACTCAGGGCAAGAGGAATACAATAAATTT
AAGCATATGTTAAATATGTCTGGTAAATTAAAACTTAATTAACTAAAAATTAAAAAAAAA
TACTTTATTAAATTAATAGAAATTGCTGAAGCCTCAGTTGAATATTCATCTGGAGAAGTT
TCTAAAAAAATGATGATACCAGCTGCTTAAAAATAATAGAAATCAAATTTCACAAAAAAG
TGA