Identifiers and Description

Gene Model Identifier

TTHERM_00384800

Standard Name

NOPP52 (NucleOlar PhosphoProtein 52 )

Aliases

PreTt24772 | 41.m00179

Description

Nopp52 RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP protein; Nucleolar phosphoprotein; domain structure similar to vertebrate nucleolin and yeast NSR1; localized to macronuclear nucleoli where it is closely associated with rDNA; in vitro substrate for casein kinase II

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• nucleolus (IDA) | GO:0005730 | Ref:9109258
• macronucleus (IDA) | GO:0031039 | Ref:9109258

Domains

• ( PF07382 ) Histone H1-like nucleoprotein HC2
• ( TIGR01622 ) splicing factor, CC1-like family
• ( PF08186 ) Wound-inducible basic protein family
• ( PF00076 ) RNA recognition motif. (a.k.a. RRM,

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.6%

TetraMine Data

TTHERM_00384800

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
SGD	YNL175C	7.002638123733849e-21	NOP13 Nucleolar protein found in preribosomal complexes; con tains an RNA recognition motif (RRM)
Tetrahymena borealis	EI9_01741.1	2.9992476920535046e-16	hypothetical protein (295 aa)
Stentor Coeruleus	SteCoe_35142	0.00000000000003442477108469977
WormBase	WBGene00003902	0.00000000000009996062864481225	locus:pab-1 status:Partially _confirmed UniProt:Q7K798 protein_id:CAE54916.1
Oxytricha	Contig11442.0.g16	0.0000000000002999981760818895	RNA recognition motif_ (a_k_a_ RRM, RBD, or RNP domain)
DictyBase	DDB_G0275459	0.0000000020002373268528243	DDB_G0275459 on chromosome: 2 position 6113524 to 6114624

General Information

No Data fetched for General Information

Associated Literature

1. Ref:11381093: Savino TM, Gébrane-Younès J, De Mey J, Sibarita JB, Hernandez-Verdun D (2001) Nucleolar assembly of the rRNA processing machinery in living cells. The Journal of cell biology 153(5):1097-110
2. Ref:9109258: Smothers JF, Madireddi MT, Warner FD, Allis CD (1997) Programmed DNA degradation and nucleolar biogenesis occur in distinct organelles during macronuclear development in Tetrahymena. The Journal of eukaryotic microbiology 44(2):79-88
3. Ref:9017598: McGrath KE, Smothers JF, Dadd CA, Madireddi MT, Gorovsky MA, Allis CD (1997) An abundant nucleolar phosphoprotein is associated with ribosomal DNA in Tetrahymena macronuclei. Molecular biology of the cell 8(1):97-108

Sequences

>TTHERM_00384800(coding)
ATGTCCAAATAAGTTAAGAAGGGTCAAGTTGAAAAGAAGATTAAGGCTGAAGAAGAAAAG
AAGAAGGTTGTCTAACAATCCTCCGATGATAGTGACGATTCTTCCAGCGAAGATGAAAAG
CCTGTTGTCAATAACAAGAAGAACCAAAAGGTTTAAGAAAAGGCTGCTGAAAAGGTTACC
AAGGCTAAGAAGCAAGTTTCTGAATCTTCTGATGACAGTGAATCTGAAGAAGAAAAGCCT
GCCCCCAAGAAGGCTGTCGCTGCTAAGACTGCTCCTGTTGCCAAGAAGGCTGTTGCCAAG
AAGGAATCCTCTGATTCTGATGACAGTGAATCTGAAGAAGAAAAGCCTGCCCCCAAGAAG
GCTGTCGCTGCTAAGACTGCTCCTGTTGCCAAGAAGGCTGTTGCCAAGAAGGAATCCTCT
GATTCTGATGACAGTGAATCTGAAGAAGAAAAGCCTGCCCCCAAGAAGGCTGTCGCTGCT
AAGACTGCTCCTGCTGCCAAGAAGGCTGTTGCCAAGAAGGAATCCTCTGATTCTGATGAC
AGTGAATCTGAAGAACAAAAGCCTGCCCCCAAGAAGGCTGCCGTTAAACCCGCTGCCAAG
AAGTAAGAATCTGAAGATGAAGACAGTGATGAATCAGAAGAATAAAAGCCTGCTACCAAG
AAGGCTGAAAAGATGTAAGTCGAAGAAGAATCTTCTGAAGAATAAAAGCCTATTAAATAA
GACCAACCTATCCAAAAGGCCTAAAACGGTAATGCCAACGGTAAATAAGGTGGTGACAAG
TTCTCTAATGAAGTTATCGTTAAGGGTTTGAGCTTTGATGCTGATGAAAACGATATTGGT
AACTTCTTAGACGAAAACTGCGGTTCCGTTGCTAGAGTTAACCTCTTAAAGAACGAATAA
GGACGTTCTAAGGGTATTGCCTTCGTCAGCTTTGAAACTGAAGAAGGTTGCAACAAGGCT
GTTGAAATGAGCAACTCTGAATTCATGGGTAGATATCTTATTATTGAAAAGACCAAGCCC
AAGACTGAAAGACCTGCTCACTTACCTGTTGATGAAGACTCCAAGACTATCTTTGTTGGT
AACCTCTCTTTCAGAACCGACAAGGAAACTCTTAAGAAGTTCTTCGCCTCTTGCGGTAAG
GTTGCTGATGCTCGTATCGCTGAAGCTGATGGAAAGAGCAGAGGTTTCGGTCACGTTGAA
TTCGAAGAAAGATCCGGTGTTGAAAATGCTTTAAAGAAGGTTGGTGAATAAATCGACGGA
AGACCCATCAAGGTTGATGTCGCTGCTTCCAGAGGTAAACGTGAAGGTTTCAACAGATCC
TAAGGAAACTTCAATAACAACAGAGGTGGTCCCCGTGGTGGTAACAACTCTTTTGCTAAC
GAAAGAAAGGGTGCCATTACTTAATTCTAAGGAAAAATCCAATCTCTCTGA

>TTHERM_00384800(protein)
MSKQVKKGQVEKKIKAEEEKKKVVQQSSDDSDDSSSEDEKPVVNNKKNQKVQEKAAEKVT
KAKKQVSESSDDSESEEEKPAPKKAVAAKTAPVAKKAVAKKESSDSDDSESEEEKPAPKK
AVAAKTAPVAKKAVAKKESSDSDDSESEEEKPAPKKAVAAKTAPAAKKAVAKKESSDSDD
SESEEQKPAPKKAAVKPAAKKQESEDEDSDESEEQKPATKKAEKMQVEEESSEEQKPIKQ
DQPIQKAQNGNANGKQGGDKFSNEVIVKGLSFDADENDIGNFLDENCGSVARVNLLKNEQ
GRSKGIAFVSFETEEGCNKAVEMSNSEFMGRYLIIEKTKPKTERPAHLPVDEDSKTIFVG
NLSFRTDKETLKKFFASCGKVADARIAEADGKSRGFGHVEFEERSGVENALKKVGEQIDG
RPIKVDVAASRGKREGFNRSQGNFNNNRGGPRGGNNSFANERKGAITQFQGKIQSL

>TTHERM_00384800(gene)
ATGTCCAAATAAGTTGTAAGAATTTTATTCATAATTTTTTAGCTATTATAAAACTAATTC
ACTTTATAAATCATTTTATTAATCTATTCTTTAATCATTATAGAAGAAGGGTCAAGTTGA
AAAGAAGATTAAGGCTGAAGAAGAAAAGAAGAAGGTTGTCTAACAATCCTCCGATGATAG
TGACGATTCTTCCAGCGAAGATGAAAAGCCTGTTGTCAATAACAAGAAGAACCAAAAGGT
TTAAGAAAAGGCTGCTGAAAAGGTTACCAAGGCTAAGAAGCAAGTTTCTGAATCTTCTGA
TGACAGTGAATCTGAAGAAGAAAAGCCTGCCCCCAAGAAGGCTGTCGCTGCTAAGACTGC
TCCTGTTGCCAAGAAGGCTGTTGCCAAGAAGGAATCCTCTGATTCTGATGACAGTGAATC
TGAAGAAGAAAAGCCTGCCCCCAAGAAGGCTGTCGCTGCTAAGACTGCTCCTGTTGCCAA
GAAGGCTGTTGCCAAGAAGGAATCCTCTGATTCTGATGACAGTGAATCTGAAGAAGAAAA
GCCTGCCCCCAAGAAGGCTGTCGCTGCTAAGACTGCTCCTGCTGCCAAGAAGGCTGTTGC
CAAGAAGGAATCCTCTGATTCTGATGACAGTGAATCTGAAGAACAAAAGCCTGCCCCCAA
GAAGGCTGCCGTTAAACCCGCTGCCAAGAAGTAAGAATCTGAAGATGAAGACAGTGATGA
ATCAGAAGAATAAAAGCCTGCTACCAAGAAGGCTGAAAAGATGTAAGTCGAAGAAGAATC
TTCTGAAGAATAAAAGCCTATTAAATAAGACCAACCTATCCAAAAGGCCTAAAACGGTAA
TGCCAACGGTAAATAAGGTGGTGACAAGTTCTCTAATGAAGTTATCGTTAAGGGTTTGAG
CTTTGATGCTGATGAAAACGATATTGGTAACTTCTTAGACGAAAACTGCGGTTCCGTTGC
TAGAGTTAACCTCTTAAAGAACGAATAAGGACGTTCTAAGGGTATTGCCTTCGTCAGCTT
TGAAACTGAAGAAGGTTGCAACAAGGCTGTTGAAATGAGCAACTCTGAATTCATGGGTAG
ATATCTTATTATTGAAAAGACCAAGCCCAAGACTGAAAGACCTGCTCACTTACCTGTTGA
TGAAGACTCCAAGACTATCTTTGTTGGTAACCTCTCTTTCAGAACCGACAAGGAAACTCT
TAAGAAGTTCTTCGCCTCTTGCGGTAAGGTTGCTGATGCTCGTATCGCTGAAGCTGATGG
AAAGGTAACTAACCAATTTAAATTTATATCTAATATAATTTTTATCTGAAAATGTGATGG
GGTATAGCTTGCTTATTATTTATTTTAGGGAAATATTTTATTTGAGATTAATTAAGGGAT
AAAAGTTATAATTAGGAACATACTATACTTATTAGAGAGTTAAGTAGGAGTTTACAATAT
TAAGATATAAAAATAATAAATTACAAATAAAAAAAAAATAAATTGATTAATAAATAAATA
AATTAATCAATCAATTAATAATAGTATCTTCGTTCGTTAATAGACAAACACAATAAAAAA
TAAATAAAATTTCCCAAATTAATTAATTAATCAATTAGTAATGAATAAGTAACATTGATT
ATATTTCCCTAAATAAATCACTAAGATAATAAATTAATTAATTAATTACATGATAACTTT
TAACTTTATTCAAATATTAAATATAATTTTTAAAAATTTAGAGCAGAGGTTTCGGTCACG
TTGAATTCGAAGAAAGATCCGGTGTTGAAAATGCTTTAAAGAAGGTTGGTGAATAAATCG
ACGGAAGACCCATCAAGGTTGATGTCGCTGCTTCCAGAGGTAAACGTGAAGGTTTCAACA
GATCCTAAGGAAACTTCAATAACAACAGAGGTGGTCCCCGTGGTGGTAACAACTCTTTTG
CTAACGAAAGAAAGGGTGCCATTACTTAATTCTAAGGAAAAATCCAATCTCTCTGA