Identifiers and Description

Gene Model Identifier

TTHERM_00046470

Standard Name

MYO10 (MYOsin)

Aliases

PreTt11126 | 3.m01737 | 3824.m02887

Description

Myosin heavy chain; member of proposed myosin Class XX, distinct from previously defined myosin classes; contains predicted coiled-coil domain and IQ motifs predicted to bind a calmodulin family protein

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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Gene Ontology Annotations

Cellular Component

Molecular Function

Domains

No Data fetched for Domains

Gene Expression Profile

  • Tetrahymena Functional Genomics Database:

TetraMine Data

TTHERM_00046470

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

SourceIdentifierScoreDescription
Tetrahymena borealisEI9_01800.19.997093137033517e-262myosin (1650 aa)
OxytrichaContig18292.0.g1089.997093137033517e-262Myosin head (motor domain)
DictyBaseDDB_G02744555.001313616964319e-114myoI on chromosome: 2 position
4534415 to 4541848
SGDYAL029C5.998625834015334e-112MYO4 One of two type V myosin
motors (along with MYO2) invol
ved in actin-based transport o
f cargos; required for mRNA tr
ansport, including ASH1 mRNA,
and facilitating the growth an
d movement of ER tubules into
the growing bud along with She
3p
WormBaseWBGene000020392.999467474389571e-105locus:hum-6 Unconventional m
yosin heavy chain 6 status:P
artially_confirmed UniProt:P
91443 protein_id:CCD61190.1
Stentor CoeruleusSteCoe_40803.3057006267607343e-37

General Information

Paragraph NoGene NameParagraph Text
10MYO1,
MYO12,
MYO11,
MYO10,
MYO9,
MYO4 ,
MYO5,
MYO4,
MYO3,
MYO2,
MYO13
Proteins of the myosin superfamily are ATP-dependent molecular motors that travel unidirectionally along actin filaments. The myosin heavy chain proteins are comprised of three domains: a head (motor) domain responsible for ATP hydrolysis at the N-terminus, a neck (lever arm) region, and a C-terminal tail region. Thirteen predicted myosin heavy chain genes have been identified in the Tetrahymena genome and named MYO1-MYO13. A phylogenetic analysis comparing these predicted proteins with the 19 previously identified myosin classes suggests that Myo1p-Myo12p belong to a previously undescribed class of myosins. This new family, designated Class XX, does not include Myo13p, which did not branch with this class or any of the other classes in the analysis. The neck and tail regions of the Tetrahymena myosins include a variety of domains characterized in other myosin classes, with each protein containing one or more of the following domains: coiled-coil (which may support dimerization); IQ motif (binding sites for calmodulin or calmodulin-like proteins); FERM domain (Four-point-one protein, Ezrin, Radixin, Moesin homology); and MyTH4 domain (Myosin Tail Homology 4).

Associated Literature

  1. Ref:16505385: Foth BJ, Goedecke MC, Soldati D (2006) New insights into myosin evolution and classification. Proceedings of the National Academy of Sciences of the United States of America 103(10):3681-6
  2. Ref:15988740: Williams SA, Gavin RH (2005) Myosin genes in Tetrahymena. Cell motility and the cytoskeleton 61(4):237-43

Sequences

>TTHERM_00046470(coding)
ATGGATGGACTTAAAGATTGGAAACAAAATGGAGCTCTTTGTTGGGTTGAAAGAGAGGTA
AGTGAGAATACTAAGTAGATTTTTGAGGAGGCTGTCATCAATACAAATTATTTTAGAAAA
AATGTGCTCATCAAAGTTTAAGATAAAGAAGAAGAAGTATCTTTGGATAAATTACACTAG
AGATCTCCTTATGAATAAAATGAAGATGATATGGTCAATATGAGAATATTAAATGATGCT
GAACTTGTTATTAACATATAAAAAAGATACTAAAATAACAAAATATTCACTTATGTTGGT
CCTACTCTTCTAGTCGTTAATCCATTTTAGTATGTTCCAGGGTTAAATACTGAAGAAAAA
ATGAGGTTTTACCACAATTAAATTATAGAAAATTCTAAGGGTAATGGTTCTTTAGCTATA
AAAAGCTTAGAACCACATGTATATGCTATAGCTGCAGAGTCATTTAGATCATTATTTGAT
TAAGAGAAAAACTAAGCTATTGTTATTAGTGGTGAATCAGGAGCAGGTAAAACTGAAAAT
GCAAAGTTATGCATGAAATTTTTAACAACTAGTATAAGCTAACATAAATCTCCCGAAAAA
GTACGTCTTAGAAAAAAAACCATTTCTTCTTTAGGACCTCCAATATTAGCTAGTCCAACA
TCCTCTATGCTTAGAGAAAGCAGCAAATCATAGTCTATAGAAGAAAAGATTTTAAGTTGC
AACCCTATCTTAGAATCTTTTGGTAATGCGAAGACTATTAGAAATGATAATTCTAGTCGT
TTTGGTAAGTATGTAACATTATTCGTAGATATGATTGATACTAAGATTATTGGAGCAGAA
ATTGCAAATTATTTACTTGAAAAAGTCAGAATTATTTAATAGGGTGTAGAAGAAAGAAAT
TTTCATATATTCTATCATTTCTTGAATGGTGCTAGTGTGCAGTAACTAAGCAAATACTAT
CTAGAAATAAATGGCAAACGCTTATAGCCTTAGTATTTTAGCTACTTAAAGAATCAAAAT
ATAGAAGTAAAATCTATTGATGACTGTAAGCTTTACGAAGAAGTAGTTAATGCTTTAGAT
GTATTAGAATTAAATGAATTTGCAGATTCTATATGGAGGATACTAGCTGCTATTTTGCAT
TTGGGAAATTTACAATTTAAATAATCTTAAATAAACAAAGATTAATTTGAAGTTTCTGAT
AAGCAGCAAATATAAATTATCTCTAATCTACTTGGAATTTAAGCTGAGGAACTTGAAAGA
GAGCTAACAATTAAATAATTTAAAGTTTAAGGAGAAGGATTTGCCAAGGAATTGAGCTTA
CCAGAATGTTAAAATTAAAGAGATTCAATAGCAAAAGAGCTTTATGATAGACTTTTTAAT
TGGCTAGTGAACTAACTAAACAGGACGATAATGCCAAAAGACATTTCAAAATAGCAAATT
TTATCATCAAATTTATACAAATCAATAGGTTTATTGGATATATATGGATTTGAGGTATTC
TAAAAAAACGGTTTTGAATAATTCTTTATCAATTACACAAATGAGAGACTTCACTAATTA
TATATTTCATACGTCTTTAAGGCAGAAGAGTTAACATTTAAGGAAGAAAGACTTGAGTAG
TATTTTAAAAAGCTTGATTTTAAAGATAATTAAGATGTTATAGATGTGTTAGATAATAAT
GATAGGCAGAAGCCTCTTGGTATTTTTAAGTTGTTAGAAGATAAATGTAAACAAAAAGGA
ACTATAATAGATGCTAAATTACTTTCAGACATTTAAAAATAGCATGGAGATAAAGAAATT
TACATTAAAAATCCAAATTATAAATTTAAAAATCCAAAGAAAATAAATGACTCAACATTT
ATAATTATACATACTGCAAAGGAGGTTGAATATGATATTAAAGGATTTATAGAAAAAAAT
AAAGATGAGGTCAATGAAGGTTTAATAAATAAAATAAATAATTCATAAATAAGAGGAATC
AGTTAAATCATAAGCGAAAAGGATAAAGAATTATTAGATGAAAGCACAGCATCATAATAA
GTTAAAATGAGATAAATAAGTTAAAAATTTATATCTGAAATGTCATTTCTTATGGATGTA
CTGATGTAATGTAATGTCTAATTTATTAGATGCATAAAGCCAAATGAAGAGAAAAAACCA
TAGTTATTTAATCAGGGTTTTACTTTAAATTAAATTCGTTACTTAGGTGTATTGGAGTCA
ATTAACATCAGAAAGCAAAGTTATCCAATAAGATAAAGCTATGAATCATTTTTTAATAAA
TATTCACTCTTGATGCTAAACAAGTTAAATATTTAAGATTAAATAAATAAAAAAAGTCTT
GTTGAAGAATTGTTTAGAAAAAATTTCAGTTCAATACCAAAAGAGAACAGATTATTTGGG
GTAACAAAAATTTTTTTCAAAAACTATGAAGTTCTGCAATAAATTGAAGATATATACAAT
AAAGAAATTTCGAATATACGCAATTTAGTTCTTAGAATTGAAAGTATATAATTGTTGTTT
CTTCTTAAAAGAAAAAGAGCTTCTGAAATAATTTAAAGTTACTGCTTTTAGAAAACAGCT
ATCTCTTATTATGAGCAAGCGATGGAAAATATAAAAAAAATATAATTCCATTGGAGAGCA
GCTTATTAGAGACTTAGAGAAGTTAGAAGTAAAAGAATCAAAAATACTTATATTATAAAG
GAAGTTTTGAATAAAGCTTGGTAAAAAATATTTACCAGATCAGTTACGACAATAGTTGAA
AAGACAAAAAAGCTAGTAAGATGCTATTACTTAAAGTAGATGTTTTCAAAACAACTCTAT
GAAATAAGAACAAAAAAAGCAGCTGTTATTTTTCTGAAACTTTTAAAAGGAAACTTTGTT
AGAAAAAGAATAAAAAGGTTTAATTTAGCTGCATAGAAGATACAAGCCAAAGTTAAGTAG
ATTTGGCTTACTGAATTATATTAAAAATTGAGAAAAGCAATAATTATTATTTAAAGAAAT
GCTAGAATATTTATCATAAGAAAAAGAGAAAGGAATTAAAGAAATGCAGAATTTTTAGGA
CCATTAGAATAAAATCTAAAAAGAATACGTATTTCTGAAGAATTGCTTCTATTTAATGGT
TAGTCTAAAGTTATTGATTAAAACACTTCTTTATAAAATGAGATATTCCGTCTAGACAAG
AGTTTAGAAAATGTTTTAGAAAAATCACATGAGCACTTCTTTTAGTAGAGAATGTATTTG
TTTAGTTATGTCATTGATTTTGAAATATTATCTGATACAAGCGAAATTTATGATCCTTTG
TGGTCATCTTTATACCAAGCTTCGTTTAAGGATAACTACGATAAACAGTCATATATCTAG
CACATTTCAATAGGAGATACTCACAGCTTAACCTGTAGCTTAAGCAGTAAGATTCATACT
TGGGGATGGAACGATTTTGGGTAACTGGGAGTACCAATTGTAGATGAAGACGATCCTAAC
CAAGAATAAAACGTTTATACTGGTACATCAATTTACTCGATGAATGTCCCTCCTTAAATT
AAAAGAATTGCACAAATTTCTTCTGGTAGTAATCATTCTTTGCTACTTGATCACAGAGGG
TAAATATGGTCTTGGGGTTGCAACAACAGAGGATAATTGGGACTGAATCATTATGAAAAT
ATGGAAACACCGTAAAAGATTACATATCTAATGAATCCCAAAACCGAGTTTTGCAAAGTT
GAGTGCAGAGATGATGAAAACTATGCTATCACAAAAAGTGGTTAACTATTTCACTGGCCC
ACTCTAGGAATGTAAGGTGAGTGTGTGAATTACCCCCTTGAGGTAGTCATACCTAAAATA
ACCATTAAAGATGTGAGCTGTGGCCATAAATTTGTAATGATTTTAAGTAACTCTGGGCTT
TTATTTAGTTATGGAGAAAACAAAGAAGGCTAATTAGGATTAGGAGATCTGAATCCAAGA
AAAATACCTACTCTAGTTTACTGTTTGAGAGATGCTGGAGAGAAAATAAGCTAAATAGAT
TGCGGATTTAAGCACACAATATGCAAAACATCTTTAGGTAAGGTTTATACTTGGGGATGG
GGAGGAAGAGGATAACTAGGACATGGAACAACAAATAATGAAATATACCCAAGAATTTTG
TCATTTTCTAATTTGGCCAAAGATAAATAGACTCCAACGTTATTTAAAGATAAATGCCTG
CAGGTAGTGGCAGGACATAGATGCTCGATGCTTTTAATGGAAAGCAGGAAAATTTATCAA
TTTGGCTCCAATTCATCATTAGATCATTAATCTTTCCCAGTTGAATTTAATATCAGATCG
AAAAGCGACAAATTAAGCTAGAATTTTTATGAGCCGATCAGAATCCAATCTTCATGGAGT
AAAACATTAAGCTTAATATATGTTACTTATGGAAATACAAAAAATTGTTTTGAAAAAAAT
ACTGTCCTAAAAACAAAAACAATAAATAATCTAACTTAAAAATGGGCTGATACAAACATA
GATACAATTGACCCTCCATTTATAGAAAAGATAGCAAACTATATTTCAGAGAAAAATATG
AAAATGCCTTTGTTTAAAATGCCTACGATGCAGTTCGAATCCAAAATTAAATATAATTAA
CTTAAACACGAACTTATCGAGGCTGATTAAATGAATAAAATTGAAATAGAGTATATGAAT
GCCTTGCAATACGAATAATAAGAAATTTATAATCAAAACCATCTAAGCTAAGGCAATCAT
TTATTAATTGAAGATCCTTAACTCACTTACTAAAACAGGTAAGTATTAGAAGAAATTAAT
TTCTAAAGAGAAAACTGGGAGGAATTTTAATCATTGGGTTTGGCACAAAGCACAAAAGAC
AGTTTAGTTGATCTTAACTATGAAGAATATTTTAGAAATTAGCAAGAATTATAATAGAGA
ATTATCTAAGAACAACAATAATAATTATAATAAGAAGAGGAAAACAGGGCTATAATAAAC
TCTTAGAAACTGAGTTAAAAGAAATAATACCCATCTTATAAAAAGTCAAACACTACATAA
TATCAAGTCGTAGAAATACCTGAAAGCAAGTCAAATGCAAGTATATCTAATAATTCTATT
AATAATAGTAAGAGACTTGATCAAAAAAGTATTAACGACACACTATCTAAGGCCTCTTCA
TCATCTTTTAATAATAAATAAAAAAGCAGTAGTAATTAGTCCTCATAAAATATAAAAAAT
TCATCAGTTGTGCAATAAGCTAATTAATAAAGTTTATCATTTTTTGAATAGCAAGGAAAC
TTAGATAGGAGATAAATGTTATAAATAGTAAAGGAAAAAGTGCTACAATTATCTAAAGTA
CCTGAAAATGAATGGACAGAAAATGATAGAAAATTTATGTAAGGAGCAATGCAATTAAGT
TAATTTGACTTTGATAATGCTTCTGAAAATAACTTATCTAAATCATAAGATAATAGTTCA
ATTAATAATAGTCAGGCAAGCTAAAGAATGGAATAAATACCTACTGATAAAGCATAGTAA
AATAACAGGGCTAGTATCAGCTCAAATTCTTCTAAAAAAAGTGCAATCTCTCAAAAAAGT
TAAAATCAACAAGAAAAAAATTAAAAGTAATAAATAAATCCTCAGCTTATTAATGTCAAA
AAGAAATGGGATGAAATCAGAAACACTCCATAATAGCAGTGGACATAAAATGACTATCAA
TTTATGGAAATTGTAAAGGCAAATAACTTAGAAAAAGTTTTATTAGAATTTGATTGA


>TTHERM_00046470(protein)
MDGLKDWKQNGALCWVEREVSENTKQIFEEAVINTNYFRKNVLIKVQDKEEEVSLDKLHQ
RSPYEQNEDDMVNMRILNDAELVINIQKRYQNNKIFTYVGPTLLVVNPFQYVPGLNTEEK
MRFYHNQIIENSKGNGSLAIKSLEPHVYAIAAESFRSLFDQEKNQAIVISGESGAGKTEN
AKLCMKFLTTSISQHKSPEKVRLRKKTISSLGPPILASPTSSMLRESSKSQSIEEKILSC
NPILESFGNAKTIRNDNSSRFGKYVTLFVDMIDTKIIGAEIANYLLEKVRIIQQGVEERN
FHIFYHFLNGASVQQLSKYYLEINGKRLQPQYFSYLKNQNIEVKSIDDCKLYEEVVNALD
VLELNEFADSIWRILAAILHLGNLQFKQSQINKDQFEVSDKQQIQIISNLLGIQAEELER
ELTIKQFKVQGEGFAKELSLPECQNQRDSIAKELYDRLFNWLVNQLNRTIMPKDISKQQI
LSSNLYKSIGLLDIYGFEVFQKNGFEQFFINYTNERLHQLYISYVFKAEELTFKEERLEQ
YFKKLDFKDNQDVIDVLDNNDRQKPLGIFKLLEDKCKQKGTIIDAKLLSDIQKQHGDKEI
YIKNPNYKFKNPKKINDSTFIIIHTAKEVEYDIKGFIEKNKDEVNEGLINKINNSQIRGI
SQIISEKDKELLDESTASQQVKMRQISQKFISEMSFLMDVLMQCNVQFIRCIKPNEEKKP
QLFNQGFTLNQIRYLGVLESINIRKQSYPIRQSYESFFNKYSLLMLNKLNIQDQINKKSL
VEELFRKNFSSIPKENRLFGVTKIFFKNYEVLQQIEDIYNKEISNIRNLVLRIESIQLLF
LLKRKRASEIIQSYCFQKTAISYYEQAMENIKKIQFHWRAAYQRLREVRSKRIKNTYIIK
EVLNKAWQKIFTRSVTTIVEKTKKLVRCYYLKQMFSKQLYEIRTKKAAVIFLKLLKGNFV
RKRIKRFNLAAQKIQAKVKQIWLTELYQKLRKAIIIIQRNARIFIIRKRERNQRNAEFLG
PLEQNLKRIRISEELLLFNGQSKVIDQNTSLQNEIFRLDKSLENVLEKSHEHFFQQRMYL
FSYVIDFEILSDTSEIYDPLWSSLYQASFKDNYDKQSYIQHISIGDTHSLTCSLSSKIHT
WGWNDFGQLGVPIVDEDDPNQEQNVYTGTSIYSMNVPPQIKRIAQISSGSNHSLLLDHRG
QIWSWGCNNRGQLGLNHYENMETPQKITYLMNPKTEFCKVECRDDENYAITKSGQLFHWP
TLGMQGECVNYPLEVVIPKITIKDVSCGHKFVMILSNSGLLFSYGENKEGQLGLGDLNPR
KIPTLVYCLRDAGEKISQIDCGFKHTICKTSLGKVYTWGWGGRGQLGHGTTNNEIYPRIL
SFSNLAKDKQTPTLFKDKCLQVVAGHRCSMLLMESRKIYQFGSNSSLDHQSFPVEFNIRS
KSDKLSQNFYEPIRIQSSWSKTLSLIYVTYGNTKNCFEKNTVLKTKTINNLTQKWADTNI
DTIDPPFIEKIANYISEKNMKMPLFKMPTMQFESKIKYNQLKHELIEADQMNKIEIEYMN
ALQYEQQEIYNQNHLSQGNHLLIEDPQLTYQNRQVLEEINFQRENWEEFQSLGLAQSTKD
SLVDLNYEEYFRNQQELQQRIIQEQQQQLQQEEENRAIINSQKLSQKKQYPSYKKSNTTQ
YQVVEIPESKSNASISNNSINNSKRLDQKSINDTLSKASSSSFNNKQKSSSNQSSQNIKN
SSVVQQANQQSLSFFEQQGNLDRRQMLQIVKEKVLQLSKVPENEWTENDRKFMQGAMQLS
QFDFDNASENNLSKSQDNSSINNSQASQRMEQIPTDKAQQNNRASISSNSSKKSAISQKS
QNQQEKNQKQQINPQLINVKKKWDEIRNTPQQQWTQNDYQFMEIVKANNLEKVLLEFD


>TTHERM_00046470(gene)
ATGGATGGACTTAAAGATTGGAAACAAAATGGTAATTTTATTTGAAACAAAATTTATATT
TTTATGAGGATAACTTTTAATGAGTAAATATAATTTAATAAAATGGAAGATAATTAGAAG
TTAATTAATTTAGAGCCTATCACTTAAATTTTATAATAAATATTATTTTTTATTTAGGAG
CTCTTTGTTGGGTTGAAAGAGAGGTAAGTGAGAATACTAAGTAGATTTTTGAGGAGGCTG
TCATCAATACAAATTATTTTAGAAAAAATGTGCTCATCAAAGTTTAAGATAAAGAAGAAG
AAGTATCTTTGGATAAATTACACTAGAGATCTCCTTATGAATAAAATGAAGATGATATGG
TCAATATGAGAATATTAAATGATGCTGAACTTGTTATTAACATATAAAAAAGATACTAAA
ATAACAAAATATTCACTTATGTTGGTCCTACTCTTCTAGTCGTTAATCCATTTTAGTATG
TTCCAGGGTTAAATACTGAAGAAAAAATGAGGTTTTACCACAATTAAATTATAGAAAATT
CTAAGGGTAATGGTTCTTTAGCTATAAAAAGCTTAGAACCACATGTATATGCTATAGCTG
CAGAGTCATTTAGATCATTATTTGATTAAGAGAAAAACTAAGCTATTGTTATTAGTGGTG
AATCAGGAGCAGGTAAAACTGAAAATGCAAAGTTATGCATGAAATTTTTAACAACTAGTA
TAAGCTAACATAAATCTCCCGAAAAAGTACGTCTTAGAAAAAAAACCATTTCTTCTTTAG
GACCTCCAATATTAGCTAGTCCAACATCCTCTATGCTTAGAGAAAGCAGCAAATCATAGT
CTATAGAAGAAAAGGTAATAATATTATTTTAATTTAAGTTATTAATTGATTATTATATTA
AAACCATTACTAATTTATTTGTATTTTATTAAAATTTTTTTTTGAATTTAGATTTTAAGT
TGCAACCCTATCTTAGAATCTTTTGGTAATGCGAAGACTATTAGAAATGATAATTCTAGT
CGTTTTGGTAAGTATGTAACATTATTCGTAGATATGATTGATACTAAGATTATTGGAGCA
GAAATTGCAAATTATTTACTTGAAAAAGTCAGAATTATTTAATAGGTGAGCTATTTATTT
ATCTATATATTTCTTTCACTATTAATTAACTAAATAATAATTTGAATTAGGGTGTAGAAG
AAAGAAATTTTCATATATTCTATCATTTCTTGAATGGTGCTAGTGTGCAGTAACTAAGCA
AATACTATCTAGAAATAAATGGCAAACGCTTATAGCCTTAGTATTTTAGCTACTTAAAGA
ATCAAAATATAGAAGTAAAATCTATTGATGACTGTAAGCTTTACGAAGAAGTAGTTAATG
CTTTAGATGTATTAGAATTAAATGAATTTGCAGATTCTATATGGAGGATACTAGCTGCTA
TTTTGCATTTGGGAAATTTACAATTTAAATAATCTTAAATAAACAGTATGACATTTTTTC
TTTGACTTATCAAGGTAGAAAATAATATATTATTAATAAATAAATAATTTTAGAAGATTA
ATTTGAAGTTTCTGATAAGCAGCAAATATAAATTATCTCTAATCTACTTGGAATTTAAGC
TGAGGAACTTGAAAGAGAGCTAACAATTAAATAATTTAAAGTTTAAGGAGAAGGATTTGC
CAAGGAATTGAGCTTACCAGAATGTTAAAATTAAAGAGATTCAATAGCAAAAGAGCTTTA
TGATAGACTTTTTAATTGGCTAGTGAACTAACTAAACAGGACGATAATGCCAAAAGACAT
TTCAAAATAGCAAATTTTATCATCAAATTTATACAAATCAATAGGTTTATTGGATATATA
TGGATTTGAGGTATTCTAAAAAAACGGTTTTGAATAATTCTTTATCAATTACACAAATGA
GAGACTTCACTAATTATATATTTCATACGTCTTTAAGGCAGAAGAGTTAGTAAGAATAAT
TAAAAAAAATAAAAATACTTTTTAATTTAAATTTCATTTGTAATAAATAGACATTTAAGG
AAGAAAGACTTGAGTAGTATTTTAAAAAGCTTGATTTTAAAGATAATTAAGATGTTATAG
ATGTGTTAGATAATAATGATAGGCAGAAGCCTCTTGGTATTTTTAAGTTGTTAGAAGATA
AATGTAAACAAAAAGGAACTATAATAGATGCTAAATTACTTTCAGACATTTAAAAATAGC
ATGGAGATAAAGAAATTTACATTAAAAATCCAAATTATAAATTTAAAAATCCAAAGAAAA
TAAATGACTCAACATTTATAATTATACATACTGCAAAGGAGGTTGAATATGATATTAAAG
GATTTATAGAAAAAAATAAAGATGAGGTCAATGAAGGTTTAATAAATAAAATAAATAATT
CATAAATAAGAGGAATCAGTTAAATCATAAGCGAAAAGGGTATTAAAAATATAATTAAAA
AACTTTAAGAGCTTTTATTTATTTATATTTAAAATTTTTTAAAGATAAAGAATTATTAGA
TGAAAGCACAGCATCATAATAAGTTAAAATGAGATAAATAAGTTAAAAATTTATATCTGA
AATGTCATTTCTTATGGATGTACTGATGTAATGTAATGTCTAATTTATTAGATGCATAAA
GCCAAATGAAGAGAAAAAACCATAGTTATTTAATCAGGGTTTTACTTTAAATTAAATTCG
TTACTTAGGTGTATTGGAGTCAATTAACATCAGAAAGCAAAGTTATCCAATAAGATAAAG
CTATGAATCATTTTTTAATAAATATTCACTCTTGATGCTAAACAAGTTAAATATTTAAGA
TTAAATAAATAAAAAAAGTCTTGTTGAAGAGTAAGAATAATTTTATTTTGCTTTTATAAA
AAAAATTATTTAAAATTTATTTTTTATGTTCAAATAGATTGTTTAGAAAAAATTTCAGTT
CAATACCAAAAGAGAACAGATTATTTGGGGTAACAAAAATTTTTTTCAAAAACTATGAAG
TTCTGCAATAAATTGAAGATATATACAATAAAGAAATTTCGAATATACGCAATTTAGTTC
TTAGAATTGAAAGTATATAATTGTTGTTTCTTCTTAAAAGAAAAAGAGCTTCTGAAATAA
TTTAAAGTTACTGCTTTTAGAAAACAGCTATCTCTTATTATGAGCAAGCGATGGAAAATA
TAAAAAAAATATAATTCCATTGGAGAGCAGCTTATTAGAGACTTAGAGAAGTTAGAAGTA
AAAGAATCAAAAATACTTATATTATAGTAATATTATTTTTATTTATTTATTTATTTGTTT
AAGAAAATTATATTTAAAGAAGGAAGTTTTGAATAAAGCTTGGTAAAAAATATTTACCAG
ATCAGTTACGACAATAGTTGAAAAGACAAAAAAGCTAGTAAGATGCTATTACTTAAAGTA
GATGTTTTCAAAACAACTCTATGAAATAAGAACAAAAAAAGCAGCTGTTATTTTTCTGAA
ACTTTTAAAAGGAAACTTTGTTAGAAAAAGAATAAAAAGGTTTAATTTAGCTGCATAGAA
GATACAAGCCAAAGTTAAGTAGATTTGGCTTACTGAATTATATTAAAAATTGAGAAAAGC
AATAATTATTATTTAAAGAAATGCTAGAATATTTATCATAAGAAAAAGAGAAAGGAATTA
AAGAAATGCAGAATTTTTAGGACCATTAGAATAAAATCTAAAAAGAATACGTATTTCTGA
AGAATTGCTTCTATTTAATGGTTAGTCTAAAGTTATTGATTAAAACACTTCTTTATAAAA
TGAGATAGTAAAATTTAATATATTAATTTGTTTTTAAAGTAGTAATCTTTTCAATTTAAA
ATTAGTTCCGTCTAGACAAGAGTTTAGAAAATGTTTTAGAAAAATCACATGAGCACTTCT
TTTAGTAGAGAATGTATTTGTTTAGTTATGTCATTGATTTTGAAATATTATCTGATACAA
GCGAAATTTATGATCCTTTGTGGTCATCTTTATACCAAGCTTCGTTTAAGGATAACTACG
ATAAACAGTCATATATCTAGCACATTTCAGTATAATTTAAAATAAATTAAATATATTTTT
ATTGAATTTTTATTGTAATTCAGATAGGAGATACTCACAGCTTAACCTGTAGCTTAAGCA
GTAAGATTCATACTTGGGGATGGAACGATTTTGGGTAACTGGGAGTACCAATTGTAGATG
AAGACGATCCTAACCAAGAATAAAACGTTTATACTGGTACATCAATTTACTCGATGAATG
TCCCTCCTTAAATTAAAAGAATTGCACAAATTTCTTCTGGTAGTAATCATTCTTTGCTAC
TTGATCACAGAGGGTAAATATGGTCTTGGGGTTGCAACAACAGAGGTAAATAAAATTATT
GTTAAAAATTAATATTAATTCTATAATATTAATTAGGATAATTGGGACTGAATCATTATG
AAAATATGGAAACACCGTAAAAGATTACATATCTAATGAATCCCAAAACCGAGTTTTGCA
AAGTTGAGTGCAGAGATGATGAAAACTATGCTATCACAAAAAGTGGTTAACTATTTCACT
GGCCCACTCTAGGTAATAAAAATAAAATAACAATATAATAGAAAAATAAACTATTAATTT
TAAAAAGGAATGTAAGGTGAGTGTGTGAATTACCCCCTTGAGGTAGTCATACCTAAAATA
ACCATTAAAGATGTGAGCTGTGGCCATAAATTTGTAATGATTTTAAGTAACTCTGGGCTT
TTATTTAGTTATGGAGAAAACAAAGAAGGCTAATTAGGATTAGGAGATCTGAATCCAAGA
AAAATACCTACTCTAGTTTACTGTTTGAGAGATGCTGGAGAGAAAATAAGCTAAATAGAT
TGCGGATTTAAGCACACAATATGCAAAACATCTTTAGGTATTTAAATATTACTTTTTTAT
GAAACTAAATTTATTTTTTAGGTAAGGTTTATACTTGGGGATGGGGAGGAAGAGGATAAC
TAGGACATGGAACAACAAATAATGAAATATACCCAAGAATTTTGTCATTTTCTAATTTGG
CCAAAGATAAATAGACTCCAACGTTATTTAAAGATAAATGCCTGCAGGTAGTGGCAGGAC
ATAGATGCTCGATGCTTTTAATGGAAAGCAGGAAAATTTATCAATTTGGCTCCAATTCAT
CATTAGATCATTAATCTTTCCCAGTTGAATTTAATATCAGATCGAAAGTAACCAAAACAA
CTTACATTATTTTTTTAATCTTATATTAAATTATCAAGAGCGACAAATTAAGCTAGAATT
TTTATGAGCCGATCAGAATCCAATCTTCATGGAGTAAAACATTAAGCTTAATATATGTTA
CTTATGGAAATACAAAAAATTGTTTTGAAAAAAATACTGTCCTAAAAACAAAAACAATAA
ATAATCTAACTTAAAAATGGGCTGATACAAACATAGATACAAGTAAATACTTTCAATGGA
TACTTATTTTTATCTTAATGGTATTTATGACTATTTTTTAAATAAAAATATAGTTGACCC
TCCATTTATAGAAAAGATAGCAAACTATATTTCAGAGAAAAATATGAAAATGCCTTTGTT
TAAAATGCCTACGATGCAGTTCGAATCCAAAATTAAATATAATTAACTTAAACACGAACT
TATCGAGGCTGATTAAATGAATAAAATTGAAATAGAGTATATGAATGCCTTGCAATACGA
ATAATAAGAAATTTATAATCAAAACCATCTAAGCTAAGGCAATCATTTATTAATTGAAGA
TCCTTAACTCACTTACTAAAACAGGTAAGTATTAGAAGAAATTAATTTCTAAAGAGAAAA
CTGGGAGGAATTTTAATCATTGGGTTTGGCACAAAGCACAAAAGACAGTTTAGTTGATCT
TAACTATGAAGAATATTTTAGAAATTAGCAAGAATTATAATAGAGAATTATCTAAGAACA
ACAATAATAATTATAATAAGAAGAGGAAAACAGGGCTATAATAAACTCTTAGAAACTGAG
TTAAAAGAAATAATACCCATCTTATAAAAAGTCAAACACTACATAATATCAAGTCGTAGA
AATACCTGAAAGCAAGTCAAATGCAAGTATATCTAATAATTCTATTAATAATAGTAAGAG
ACTTGATCAAAAAAGTATTAACGACACACTATCTAAGGCCTCTTCATCATCTTTTAATAA
TAAATAAAAAAGCAGTAGTAATTAGTCCTCATAAAATATAAAAAATTCATCAGTTGTGCA
ATAAGCTAATTAATAAAGTTTATCATTTTTTGAATAGCAAGGAAACTTAGATAGGTAAGA
TTAAAAAATAAATCCTTAATTATTGTTGAATTTAACAAATATTTTTTTATTTTATAGGAG
ATAAATGTTATAAATAGTAAAGGAAAAAGTGCTACAATTATCTAAAGTACCTGAAAATGA
ATGGACAGAAAATGATAGAAAATTTATGTAAGGAGCAATGCAATTAAGTTAATTTGACTT
TGATAATGCTTCTGAAAATAACTTATCTAAATCATAAGATAATAGTTCAATTAATAATAG
TCAGGCAAGCTAAAGAATGGAATAAATACCTACTGATAAAGCATAGTAAAATAACAGGGC
TAGTATCAGCTCAAATTCTTCTAAAAAAAGTGCAATCTCTCAAAAAAGTTAAAATCAACA
AGAAAAGTAATTAAAAATAAATTAAATATTAATCAAATCTAATTTTATTTAAAAAGAAAT
TAAAAGTAATAAATAAATCCTCAGCTTATTAATGTCAAAAAGAAATGGGATGAAATCAGA
AACACTCCATAATAGCAGTGGACATAAAATGACTATCAATTTATGGAAATTGTAAAGGCA
AATAACTTAGAAAAAGTTTTATTAGAATTTGATTGA