Identifiers and Description

Gene Model Identifier

TTHERM_01145010

Standard Name

MRS1 (methionyl-tRNA synthetase 1)

Aliases

PreTt01416 | 253.m00041

Description

MRS1 methionine-tRNA ligase; methionyl-tRNA synthetase

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• cytoplasm (IEA) | GO:0005737

Molecular Function

• ATP binding (IEA) | GO:0005524
• aminoacyl-tRNA ligase activity (IEA) | GO:0004812
• nucleotide binding (IEA) | GO:0000166

Biological Process

• tRNA aminoacylation for protein translation (IEA) | GO:0006418
• translation (IEA) | GO:0006412

Domains

• ( PF00412 ) LIM domain
• ( PF06519 ) TolA protein
• ( PF07975 ) TFIIH C1-like domain
• ( TIGR00422 ) valyl-tRNA synthetase
• ( TIGR00396 ) leucyl-tRNA synthetase
• ( TIGR00392 ) isoleucine--tRNA ligase
• ( TIGR00398 ) methionyl-tRNA synthetase
• ( PF09334 ) tRNA synthetases class I (M)
• ( PF00133 ) tRNA synthetases class I (I,

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 11.7%

TetraMine Data

TTHERM_01145010

WebApollo

Fullscreen View

Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Stentor Coeruleus	SteCoe_6427	0
WormBase	WBGene00003415	9.997093137033517e-262	locus:mars-1 status:Partiall y_confirmed UniProt:D3YT55 protein_id:CBK19452.1
Tetrahymena borealis	EI9_19320.1	9.997093137033517e-262	methionyl-tRNA synthetase (838 aa)
DictyBase	DDB_G0279113	9.997093137033517e-262	metS on chromosome: 3 position 1648404 to 1650743
Oxytricha	Contig1085.1.g65	9.997093137033517e-262	tRNA synthetases class I (M)
SGD	YGR264C	9.997093137033517e-262	MES1 Methionyl-tRNA synthetase , forms a complex with glutamy l-tRNA synthetase (Gus1p) and Arc1p, which increases the cat alytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_01145010(coding)
ATGGAAGTTAAACTTAGAAAATTCACAACCAAGGGTTAAGCACTTGTTGCTTCAGCCAAC
CTTTTCCATGAGGAAAAAAAGATTACATTCTCAAGGGATGAATCTGTAGCAAATGACACT
CTTGCTGTCTAAAATTAATAAGCAATTAGCGGATGGACTGCTATTTTCTCTTATCTCCTC
TAGTTAAAGATTGATAGTCCTTTATTTGGTGATTTCTACTTTGTTTGCAACTAATTGAAG
AGTGGTAAAAGATAAGTAGAAGAAAATGCCTTAGAAAATTTGAATAAAATACTTTCTACC
AGATAATTCTTAAGCGGAGAAGAACTTGGTGAAATTGATGTTATTGCTTACACTCGTGTC
AGAGCCTTTGTTAAGGATCTTCCTTTCAGCATTAAGCGTTTTACCCATCTCCACGATTGG
TTTGTTGCTGCTTAATCAACCTTAGAAGATGCTGTTAGCAAAGCTGAAACTTTCGTTGCT
TAACCTGTTGTTAAGGAAAAGAAAGCTGCTGGAAAAAAACCAGAAGGCAAACCTGAAAAA
CCAGAAAAGGCTGAAAAAACTGAAAATCCTAAAAAGGCTGAAAAAACAGAAAAAGCTGAA
AACCCTAAGAAGGCTGAAAAGGCTGAGAAAAAGGAAGCCAAAAAAGAAAAGGCTGAAAAA
CCTGCTGCTACTGAAGCTCCTAAAAAGGCTCCTGCTAAAGTTGATACTATCGATCCTGCT
TATAAGGAAAAAATTAACAATATTAGATTCGTTAGAAGCAATAAGGGTGAACCCGTTTTA
CCAGTAGATGGTTAAAGAAACATTTTGATCACCTCTGCTCTTCCTTACGTCAATAACGCT
CCTCACTTGGGTACATTGATTGGATGTGTCTTGAGTGGTGATGTTTTTGCTAGATATTGC
AGATCTAGAGGTTATAATACAATTTACATTTGTGGTACTGATGAATACGGTACTGCCACT
GAAATGAAGGCTCTTCAAGAAAAGACTACTCCTGCTGAAATTTGTACTAAGTACTATAAG
ATTTAAAAGGATGTCTATGATTGGTTTGATATCGATTTTGATATTTTCGGAAGAACCACT
ACTGAAAAGCACACCAAGATTTCTCAAGATATTTTCTTAACTCTTCATAAGAATGGTTAC
ATCAAGGAAGACATCATGCACCAAAGTTTCTGTGCTGCTTGTGATAAATTCTTAGCAGAC
AGATACGTTAACGGTACTTGCCCCTTCTGCTAACACGATGATTGCCACGGTGATTAATGT
GATAAGTGTGGTAAACTCGTTAATCCTGCCGAACTCATCAATCCTAAATGTACAATTTGC
AAGAATCCTTCTGTTATTAAAGAAACTAAGCACTGCTTCCTCGATTTACCTCAACTTGAA
AAAGAAATCGACGAATTCATTGAAAAGAGATCAAAGGAAGGAGATTGGAGTGATAACGCA
TATAAAACATCCAAGGCTTGGATTAAGAATGGTTTAAAATATAGATGCATTACTAGAGAT
TTAAAATGGGGTACTCCTATTCCTCTTGCTGGTTGGGAAAACAAGGTTATGTACGTATGG
TTCGATGCTCCTATTGGTTATCCTTCCATTACTGCTAATTTGGTTGAAGACTGGGAAAAA
TGGTGGAAAAACCCTGAAAATGTTAAACTTTATCAATTCATCGGTAAGGACAATATTCCT
TTCCACTGTGTCATCTTCCCTGGTACTCTCTTGGGAACTCGTGAAAACTGGACACTACTC
AACTCTATGTCATCTTGTGAATATCTTTAATACGAATCTGGTAAATTCTCTAAGAGTAAA
TGCGTTGGTGTATTTGGTGATGACGCCTAAAAGACTGGCATTCCCGTTGAAGTTTGGAGA
TATTACCTTTTGATTAACAGACCTGAATAAAACGATACTAATTTCTAATGGAGTGACTTT
GCTGCTAAGAATAACAACGAACTTCTTCCTAACGTTGGTAACCTTGTTCAACGTATTTTG
AAATTCCTCTACTCTAAGTTAGAAAAGAAAGTACCTACTTTAGATTTCAGTCTATTGAAC
GAAGAAGATAAGAACTGGTTAGCTTCTATTTGGAATTTGTTCCAACAATATCTTTCTCAT
ATGGAAAAGGTAGAACTCAAGAGTGCTCTTAAGGTTGTTATGTAAATTTCTTCTGAAGGT
AATAATTATATGCAAAAGAATGAACCTTGGAACAAGGCCAACCAAGAAACTGGTAGACAC
ATTGTCTCATTGTTCGTTTTGGTCAACATCATTAGATTCCTCTCTGCCTTATTCGAACCT
TTCATGCCTACTCTCAGTGCTAAAATTAATTTCATGTTGGGTTACGAAGCCAGAACCGCT
AAAGATGAAAAGATCCTTGAATTTATCAGTTCTCAACCTGATGCTATCTCTGGTCTCCTT
TCTCTTGTTCCTGGTGGATAAATCTTAAATGAACCCATTCCTATTTTCAGAAAATTGGAA
GATGATGAAATTGAAAACTTCAAGTTATAATTCAGCGGTGGAAAGAAATTGTGA

>TTHERM_01145010(protein)
MEVKLRKFTTKGQALVASANLFHEEKKITFSRDESVANDTLAVQNQQAISGWTAIFSYLL
QLKIDSPLFGDFYFVCNQLKSGKRQVEENALENLNKILSTRQFLSGEELGEIDVIAYTRV
RAFVKDLPFSIKRFTHLHDWFVAAQSTLEDAVSKAETFVAQPVVKEKKAAGKKPEGKPEK
PEKAEKTENPKKAEKTEKAENPKKAEKAEKKEAKKEKAEKPAATEAPKKAPAKVDTIDPA
YKEKINNIRFVRSNKGEPVLPVDGQRNILITSALPYVNNAPHLGTLIGCVLSGDVFARYC
RSRGYNTIYICGTDEYGTATEMKALQEKTTPAEICTKYYKIQKDVYDWFDIDFDIFGRTT
TEKHTKISQDIFLTLHKNGYIKEDIMHQSFCAACDKFLADRYVNGTCPFCQHDDCHGDQC
DKCGKLVNPAELINPKCTICKNPSVIKETKHCFLDLPQLEKEIDEFIEKRSKEGDWSDNA
YKTSKAWIKNGLKYRCITRDLKWGTPIPLAGWENKVMYVWFDAPIGYPSITANLVEDWEK
WWKNPENVKLYQFIGKDNIPFHCVIFPGTLLGTRENWTLLNSMSSCEYLQYESGKFSKSK
CVGVFGDDAQKTGIPVEVWRYYLLINRPEQNDTNFQWSDFAAKNNNELLPNVGNLVQRIL
KFLYSKLEKKVPTLDFSLLNEEDKNWLASIWNLFQQYLSHMEKVELKSALKVVMQISSEG
NNYMQKNEPWNKANQETGRHIVSLFVLVNIIRFLSALFEPFMPTLSAKINFMLGYEARTA
KDEKILEFISSQPDAISGLLSLVPGGQILNEPIPIFRKLEDDEIENFKLQFSGGKKL

>TTHERM_01145010(gene)
ATGGAAGTTAAACTTAGAAAATTCACAACCAAGGGTTAAGCACTTGTTGCTTCAGCCAAC
CTTTTCCATGAGGAAAAAAAGATTACATTCTCAAGGGATGAATGTAAGAACAAAATATAA
TAATTCGTTTTTCATTCATTTGAAGAATCAAACATTTAATATAATAAACAATAAATAATT
TTTTTTCTATAATTTAATAAAGCTGTAGCAAATGACACTCTTGCTGTCTAAAATTAATAA
GCAATTAGCGGATGGACTGCTATTTTCTCTTATCTCCTCTAGTTAAAGATTGATAGTCCT
TTATTTGGTGATTTCTACTTTGTTTGCAACTAATTGAAGGTATTTATTACTTACTTTCCA
CTAAATAATTAAATATTTTATTCAACTATTTTATATTAAACTTATTAGAGTGGTAAAAGA
TAAGTAGAAGAAAATGCCTTAGAAAATTTGAATAAAATACTTTCTACCAGATAATTCTTA
AGCGGAGTAAATTATTTATCTATTTTTTACTTTTTTCACAAGGAGAAAATATCATTTCTA
AATTAATTAAAAATGAAAATTTCTATCAAATAGCTTAGATTAATATAAAATTATTTTAAT
ATTTTTAGGAAGAACTTGGTGAAATTGATGTTATTGCTTACACTCGTGTCAGAGCCTTTG
TTAAGGATCTTCCTTTCAGCATTAAGCGTTTTACCCATCTCCACGATTGGTTTGTTGCTG
CTTAATCAACCTTAGAAGATGCTGTTAGCAAAGCTGAAACTTTCGTTGCTTAACCTGTTG
TTAAGGAAAAGAAAGCTGCTGGAAAAAAACCAGAAGGCAAACCTGAAAAACCAGAAAAGG
CTGAAAAAACTGAAAATCCTAAAAAGGCTGAAAAAACAGAAAAAGCTGAAAACCCTAAGA
AGGCTGAAAAGGCTGAGAAAAAGGAAGCCAAAAAAGAAAAGGCTGAAAAACCTGCTGCTA
CTGAAGCTCCTAAAAAGGTAAACAATCTTTCTTAAAATATAGAATTAAAATTAGCAAAAT
ATTAAAATACCTTAATTCAACATATAAGTTTAATATATTACTAATAATTAATTTACCAAC
TTACTTAATATATAAATAAAAGGCTCCTGCTAAAGTTGATACTATCGATCCTGCTTATAA
GGAAAAAATTAACAATATTAGATTCGTTAGAAGCAATAAGGGTGAACCCGTTTTACCAGT
AGATGGTTAAAGAAACATTTTGATCACCTCTGCTCTTCCTTACGTCAATAACGCTCCTCA
CTTGGGTACATTGATTGGATGTGTCTTGAGTGGTGATGTTTTTGCTAGATATTGCAGATC
TAGAGGTTATAATACAATTTACATTTGTGGTACTGATGAATACGGTACTGCCACTGAAAT
GAAGGCTCTTCAAGAAAAGACTACTCCTGCTGAAATTTGTACTAAGTACTATAAGATTTA
AAAGGATGTCTATGATTGGTTTGATATCGATTTTGATATTTTCGGAAGAACCACTACTGA
AAAGCACACCAAGATTTCTCAAGATATTTTCTTAACTCTTCATAAGAATGGTTACATCAA
GGAAGACATCATGCACCAAAGTTTCTGTGCTGCTTGTGATAAATTCTTAGCAGACAGATA
CGTTAACGGTACTTGCCCCTTCTGCTAACACGATGATTGCCACGGTGATTAATGTGATAA
GTGTGGTAAACTCGTTAATCCTGCCGAACTCATCAATCCTAAATGTACAATTTGCAAGAA
TCCTTCTGTTATTAAAGAAACTAAGCACTGCTTCCTCGATTTACCTCAACTTGAAAAAGA
AATCGACGAATTCATTGAAAAGTAAACACAACACTAAATTATTTCAACAATATTTTAAAG
TAATTTTTAATAAAATAAATTTTAGGAGATCAAAGGAAGGAGATTGGAGTGATAACGCAT
ATAAAACATCCAAGGCTTGGATTAAGAATGGTTTAAAATATAGATGCATTACTAGAGATT
TAAAATGGGGTACTCCTATTCCTCTTGCTGGTTGGGAAAACAAGGTTATGTACGTATGGT
TCGATGCTCCTATTGGTTATCCTTCCATTACTGCTAATTTGGTTGAAGACTGGGAAAAAT
GGTGGAAAAACCCTGAAAATGTTAAACTTTATCAATTCATCGGTAAGGACAATATTCCTT
TCCACTGTGTCATCTTCCCTGGTACTCTCTTGGGAACTCGTGAAAACTGGACACTACTCA
ACTCTATGTCATCTTGTGAATATCTTTAATACGAATCTGGTAAATTCTCTAAGAGTAAAT
GCGTTGGTGTATTTGGTGATGACGCCTAAAAGACTGGCATTCCCGTTGAAGTTTGGAGAT
ATTACCTTTTGATTAACAGACCTGAATAAAACGATACTAATTTCTAATGGAGTGACTTTG
CTGCTAAGAATAACAACGAACTTCTTCCTAACGTTGGTAACCTTGTTCAACGTATTTTGA
AATTCCTCTACTCTAAGTTAGAAAAGGTAAATTAGTGTTTAAATTTTATTAATTATCATT
CTAAACTTGCATTTTTTATGAACAGAAAGTACCTACTTTAGATTTCAGTCTATTGAACGA
AGAAGATAAGAACTGGTTAGCTTCTATTTGGAATTTGTTCCAACAATATCTTTCTCATAT
GGAAAAGGTAGAACTCAAGAGTGCTCTTAAGGTTGTTATGTAAATTTCTTCTGAAGGTAA
TAATTATATGCAAAAGAATGAACCTTGGAACAAGGCCAACCAAGAAACTGGTAGACACAT
TGTCTCATTGTTCGTTTTGGTCAACATCATTAGATTCCTCTCTGCCTTATTCGAACCTTT
CATGCCTACTCTCAGTGCTAAAATTAATTTCATGTTGGGTTACGAAGCCAGAACCGCTAA
AGATGAAAAGATCCTTGAATTTATCAGTTCTCAACCTGATGCTATCTCTGGTCTCCTTTC
TCTTGTTCCTGGTGGATAAATCTTAAATGAACCCATTCCTATTTTCAGAAAATGTAAATA
AATTTTGTAAAAGTAATAAGAAATTATTAAAAAACATTAATTAAAAAAATAGTGGAAGAT
GATGAAATTGAAAACTTCAAGTTATAATTCAGCGGTGGAAAGAAATTGTGA