Identifiers and Description

Gene Model Identifier

TTHERM_00204120

Standard Name

MPK5 (Mitogen-activated Protein Kinase)

Aliases

PreTt13785 | 17.m00392 | XP_001007098

Description

Protein kinase domain containing protein. Sequence similarity to the ERK subfamily of the protein kinase MAPK family (Eisen et al., 2006). Putative mitogen-activated ERK1/2 subfamily (MAP) kinase (Yildiz&Arslanyolu, 2014)

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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Gene Ontology Annotations

Molecular Function

Biological Process

Domains

  • ( PF00069 ) protein kinase domain
  • ( PF07714 ) protein tyrosine kinase
  • ( PF05931 ) Staphylococcal AgrD protein

Gene Expression Profile

  • Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.2%

TetraMine Data

TTHERM_00204120

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

SourceIdentifierScoreDescription
Tetrahymena borealisEI9_15672.14.998444157800704e-72protein kinase domain-containi
ng protein (758 aa)
OxytrichaContig19712.0.g791.9994274381022833e-63Protein kinase domain
DictyBaseDDB_G02863531.9992362000979228e-56erkA on chromosome: 4 position
4355028 to 4356796
SGDYBL016W4.998233068678632e-48FUS3 Mitogen-activated serine/
threonine protein kinase invol
ved in mating; phosphoactivate
d by Ste7p; substrates include
Ste12p, Far1p, Bni1p, Sst2p;
inhibits invasive growth durin
g mating by phosphorylating Te
c1p, promoting its degradation
WormBaseWBGene000034019.000941515806455e-45locus:mpk-1 Mitogen-activate
d protein kinase mpk-1 statu
s:Confirmed UniProt:P39745
protein_id:CAA87057.1
Stentor CoeruleusSteCoe_170685.380186160021138e-32

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:25286252: Yıldız MT, Arslanyolu M (2014) In silico identification and characterization of the MAPK family members of unicellular model eukaryote Tetrahymena thermophila. European journal of protistology 50(5):538-50
  2. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00204120(coding)
ATGTAGAACCTTTCTAATTTTGATTCATTATCTCAATCTCAATTATAGGCTTTTAGTTAA
TAAAATCCTTTAAGATTTTTGTCATTTTAATACACTGAAAACGATTTACATTCTTTTAAT
TATTATACTAGTGTTTATAAGATAGAGAAAAGATATCGAATTTTAAAATAAATAGGCTTT
GGTTTTAATCCTACTTTCACTGCGATTGATCAAGAATATGGATAAAAAGTAATAATTGAA
GTAATAAAAATTGAAAATGATGATTTGATTTATATGAATTAACTAATTAGATAAATAAAA
ATAGAAAACCATTTTAAGCATGAAAATATTTCTTCTAATCTACATATAATGATGGAATCT
AAAAATCTCTACATAGTAAGAGAGTTCATTGATACAGATTTGCATAGAGTTAATTTCTCT
AAATAAGAATTAACTGATGATCATATCTAATATTTTACTTATTAAATATTAAGCGCTCTT
TTTTTTTTGCATTCCTAAAATGTTTACCACACTTAATTGAGACTTTCTAATATATTATTA
AATAAAAATTGCGATTTGAAAATAAGCCGTTTTATAGGTACTAATTTCCCTAATGAAATT
TATTCATAATATATAACGAGTGACTATTTCTTATCTCCATAATAAATTTTAAATTTACCT
AAAAATTTATCTAAAACTGATATATGGCATGTTGGAGTAATTATTTTAGGGCTAATTAAT
AGAGATACTTTCTTTTCCAATCTTTCTAATTAGCTTGGTGGAGGCTATTTGGGACTTATA
AATGCTATTTTTTCTTACATAGGAACTCCTTCAGGAGAGGAACTTTTATAATATTAAGAT
TATAAAGGTTTGTATTAATATATCATTAAATATAGTAAAAAATCTTGGTAGGATGTATTT
CCAGATGCAAATCCTTTATTATGTGATCTATTAGATAAAATGCTCGTTTTCAATGAAGAT
AAGCGCTATACTGTGAAAGAATGCTTACAACATCCATACTTTGAAGATTTATACGATTTG
GATGATATTGATGAGTGTGATGTAAAGTTTGATCACTCTTAATTTTAAATTGGCCTAAAT
GAAGATGAAATAATGAAGGAGATTTATTTTGAAGTTGAAAAAAGTTATTAAAAATAGTAA
AAGTAGAAGCTAAAAAGATATTAAATATAAATAATTTAAAATATTGCTTTTTAAAAGCAC
TTAGCTGATTAAATTCCTCTTAATCCTAAATTAATATTTTATAATTTATATGAAGATTTA
TGA


>TTHERM_00204120(protein)
MQNLSNFDSLSQSQLQAFSQQNPLRFLSFQYTENDLHSFNYYTSVYKIEKRYRILKQIGF
GFNPTFTAIDQEYGQKVIIEVIKIENDDLIYMNQLIRQIKIENHFKHENISSNLHIMMES
KNLYIVREFIDTDLHRVNFSKQELTDDHIQYFTYQILSALFFLHSQNVYHTQLRLSNILL
NKNCDLKISRFIGTNFPNEIYSQYITSDYFLSPQQILNLPKNLSKTDIWHVGVIILGLIN
RDTFFSNLSNQLGGGYLGLINAIFSYIGTPSGEELLQYQDYKGLYQYIIKYSKKSWQDVF
PDANPLLCDLLDKMLVFNEDKRYTVKECLQHPYFEDLYDLDDIDECDVKFDHSQFQIGLN
EDEIMKEIYFEVEKSYQKQQKQKLKRYQIQIIQNIAFQKHLADQIPLNPKLIFYNLYEDL


>TTHERM_00204120(gene)
ATGTAGAACCTTTCTAATTTTGATTCATTATCTCAATCTCAATTATAGGCTTTTAGTTAA
TAAAATCCTTTAAGATTTTTGTCATTTTAATACACTGAAAACGATTTACATTCTTTTAAT
TATTATACTAGTGTTTATAAGATAGAGAAAAGATATCGAATTTTAAAATAAATAGGCTTT
GGTTTTAATCCTACTTTCACTGCGATTGATCAAGAATATGGATAAAAAGTAATAATTGAA
GTAATAAAAATTGAAAATGATGATTTGATTTATATGAATTAACTAATTAGATAAATAAAA
ATAGAAAACCATTTTAAGCATGAAAATATTTCTTCTAATCTACATATAATGATGGAATCT
AAAAATCTCTACATAGTAAGAGAGTTCATTGATACAGATTTGCATAGAGTTAATTTCTCT
AAATAAGAATTAACTGATGATCATATCTAATATTTTACTTATTAAATATTAAGCGCTCTT
TTTTTTTTGCATTCCTAAAATGTTTACCACACTTAATTGAGACTTTCTAATATATTATTA
AATAAAAATTGCGATTTGAAAATAAGCCGTTTTATAGGTACTAATTTCCCTAATGAAATT
TATTCATAATATATAACGAGTGACTATTTCTTATCTCCATAATAAATTTTAAATTTACCT
AAAAATTTATCTAAAACTGATATATGGCATGTTGGAGTAATTATTTTAGGGCTAATTAAT
AGAGATACTTTCTTTTCCAATCTTTCTAATTAGCTTGGTGGAGGCTATTTGGGACTTATA
AATGCTATTTTTTCTTACATAGGAACTCCTTCAGGAGAGGAACTTTTATAATATTAAGAT
TATAAAGGTTTGTATTAATATATCATTAAATATAGTAAAAAATCTTGGTAGGATGTATTT
CCAGATGCAAATCCTTTATTATGTGATCTATTAGATAAAATGCTCGTTTTCAATGAAGAT
AAGCGCTATACTGTGAAAGAATGCTTACAACATCCATACTTTGAAGATTTATACGATTTG
GATGATATTGATGAGTGTGATGTAAAGTTTGATCACTCTTAATTTTAAATTGGCCTAAAT
GAAGATGAAATAATGAAGGAGATTTATTTTGAAGTTGAAAAAAGTTATTAAAAATAGTAA
AAGTAGAAGCTAAAAAGATATTAAATATAAATAATTTAAAATATTGCTTTTTAAAAGCAC
TTAGCTGATTAAATTCCTCTTAATCCTAAATTAATATTTTATAATTTATATGAAGATTTA
TGA