Identifiers and Description

Gene Model Identifier

TTHERM_00355460

Standard Name

MED31 (Mediator subunit 31)

Aliases

PreTt27532 | 37.m00249 | 3836.m02338 | SOH1

Description

Putative Subunit of the RNA polymerase II mediator complex; conserved with other metazoan MED31 subunits

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• RNA polymerase II transcription mediator activity (IEA) | GO:0016455

Biological Process

• regulation of transcription (IEA) | GO:0045449

Domains

• ( PF05669 ) SOH1

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.3%

TetraMine Data

TTHERM_00355460

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_02286.1	6.002203762674495e-72	hypothetical protein (151 aa)
DictyBase	DDB_G0285221	0.000000000000001999258566166494	med31 on chromosome: 4 positio n 2996613 to 2997218
WormBase	WBGene00007026	0.00000000000004998767099442072	locus:mdt-31 status:Confirme d UniProt:I2HAC1 protein_i d:CCH63828.1
SGD	YGL127C	0.00000019998969434520019	SOH1 Subunit of the RNA polyme rase II mediator complex; asso ciates with core polymerase su bunits to form the RNA polymer ase II holoenzyme; involved in telomere maintenance; conserv ed with other metazoan MED31 s ubunits

General Information

No Data fetched for General Information

Associated Literature

1. Ref:31280994: Garg J, Saettone A, Nabeel-Shah S, Cadorin M, Ponce M, Marquez S, Pu S, Greenblatt J, Lambert JP, Pearlman RE, Fillingham J (2019) The Med31 Conserved Component of the Divergent Mediator Complex in Tetrahymena thermophila Participates in Developmental Regulation. Current biology : CB 29(14):2371-2379.e6
2. Ref:18515835: Bourbon HM (2008) Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex. Nucleic acids research 36(12):3993-4008

Sequences

>TTHERM_00355460(coding)
ATGATGTAGCATTAAATGAGCATGCAAATTCAAAGCTAAAATCAATAAGATTAAAGCTAA
CAAGCCAACCAAGATCTTATGAATTTTAGGTCTGATTTTGAATAATACTAAAGATTTTAG
TTAGATCTTGAATTTGTCAATATGCTAGCCAATCCATATTACATTTTATAACTTTAAGAA
TATGATTATTTTTCAAACGAAAGATTTTAAAATTATTTGAAGTATTTATCATATTTCAAA
CAACCTGAATATTTCAAATTCGTTAAGTATCCACTAGGCATAAAAATGCTTGATTTAATT
TAACAAGACAAATTTATTGAAAACTTGAGTAATAACGGAATTGAATTAGCAAATAAAATG
AATATTCAAAATACTTATACTAAATAATTTTTAAATTATTTAGCAAAAAAATCTAGCTTG
TAAAAAGATATTAAAAAAGAAGAAAATTGA

>TTHERM_00355460(protein)
MMQHQMSMQIQSQNQQDQSQQANQDLMNFRSDFEQYQRFQLDLEFVNMLANPYYILQLQE
YDYFSNERFQNYLKYLSYFKQPEYFKFVKYPLGIKMLDLIQQDKFIENLSNNGIELANKM
NIQNTYTKQFLNYLAKKSSLQKDIKKEEN

>TTHERM_00355460(gene)
AAAATAAATAAATCAATTATATTTGCGAATTATAAATAGTCTAATTAGTGTTTAATATTT
TGCAAAATAAGAAAAAAAGATTTACTTACTAAAAAAATATCTTTAAAGCAAGCTAAATTT
TGGGTATTCTAATATAAAATGATGTAGCATTAAATGAGCATGCAAATTCAAAGCTAAAAT
CAATAAGATTAAAGCTAACAAGCCAACCAAGATCTTATGAATTTTAGGTCTGATTTTGAA
TAATACTAAAGATTTTAGTTAGATCTTGAATTTGTCAATATGCTAGCCAATCCATATTAC
ATTTTATGTATAATTAAATATTACATTTTAGACAAATAAAATATTTAGATTTTTTTAAAT
AGAACTTTAAGAATATGATTATTTTTCAAACGAAAGATTTTAAAATTATTTGAAGTATTT
ATCATATTTCAAACAACCTGAATATTTCAAATTCGTTAAGTAAGCTTTACTATTTAATAC
AAATCATTTCTAAGCAATTTTTTAAAAAAAGGTATCCACTAGGCATAAAAATGCTTGATT
TAATTTAACAAGACAAATTTATTGAAAACTTGAGTAATAACGGAATTGAATTAGCAAATA
AAATGAATATTCAAAATACTTATACTAAATAATTTTTAAATTATTTAGCAAAAAAATCTA
GCTTGTAAAAAGATATTAAAAAAGAAGAAAATTGA