Identifiers and Description

Gene Model Identifier

TTHERM_00355460

Standard Name

MED31 (Mediator subunit 31)

Aliases

PreTt27532 | 37.m00249 | 3836.m02338 | SOH1

Description

MED31 mediator of RNA polymerase II transcription subunit putative; Putative Subunit of the RNA polymerase II mediator complex; conserved with other metazoan MED31 subunits

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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Gene Ontology Annotations

Molecular Function

  • RNA polymerase II transcription mediator activity (IEA) | GO:0016455

Biological Process

Domains

Gene Expression Profile

  • Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.3%

TetraMine Data

TTHERM_00355460

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

SourceIdentifierScoreDescription
Tetrahymena borealisEI9_02286.16.002203762674495e-72hypothetical protein (151 aa)
DictyBaseDDB_G02852210.000000000000001999258566166494med31 on chromosome: 4 positio
n 2996613 to 2997218
WormBaseWBGene000070260.00000000000004998767099442072locus:mdt-31 status:Confirme
d UniProt:I2HAC1 protein_i
d:CCH63828.1
SGDYGL127C0.00000019998969434520019SOH1 Subunit of the RNA polyme
rase II mediator complex; asso
ciates with core polymerase su
bunits to form the RNA polymer
ase II holoenzyme; involved in
telomere maintenance; conserv
ed with other metazoan MED31 s
ubunits

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:33786459: Nabeel-Shah S, Garg J, Kougnassoukou Tchara PE, Pearlman RE, Lambert JP, Fillingham J (2021) Functional proteomics protocol for the identification of interaction partners in Tetrahymena thermophila. STAR protocols 2(1):100362
  2. Ref:31280994: Garg J, Saettone A, Nabeel-Shah S, Cadorin M, Ponce M, Marquez S, Pu S, Greenblatt J, Lambert JP, Pearlman RE, Fillingham J (2019) The Med31 Conserved Component of the Divergent Mediator Complex in Tetrahymena thermophila Participates in Developmental Regulation. Current biology : CB 29(14):2371-2379.e6
  3. Ref:18515835: Bourbon HM (2008) Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex. Nucleic acids research 36(12):3993-4008

Sequences 

>TTHERM_00355460(coding)
ATGATGTAGCATTAAATGAGCATGCAAATTCAAAGCTAAAATCAATAAGATTAAAGCTAA
CAAGCCAACCAAGATCTTATGAATTTTAGGTCTGATTTTGAATAATACTAAAGATTTTAG
TTAGATCTTGAATTTGTCAATATGCTAGCCAATCCATATTACATTTTATAACTTTAAGAA
TATGATTATTTTTCAAACGAAAGATTTTAAAATTATTTGAAGTATTTATCATATTTCAAA
CAACCTGAATATTTCAAATTCGTTAAGTATCCACTAGGCATAAAAATGCTTGATTTAATT
TAACAAGACAAATTTATTGAAAACTTGAGTAATAACGGAATTGAATTAGCAAATAAAATG
AATATTCAAAATACTTATACTAAATAATTTTTAAATTATTTAGCAAAAAAATCTAGCTTG
TAAAAAGATATTAAAAAAGAAGAAAATTGA


>TTHERM_00355460(protein)
MMQHQMSMQIQSQNQQDQSQQANQDLMNFRSDFEQYQRFQLDLEFVNMLANPYYILQLQE
YDYFSNERFQNYLKYLSYFKQPEYFKFVKYPLGIKMLDLIQQDKFIENLSNNGIELANKM
NIQNTYTKQFLNYLAKKSSLQKDIKKEEN


>TTHERM_00355460(gene)
ATGATGTAGCATTAAATGAGCATGCAAATTCAAAGCTAAAATCAATAAGATTAAAGCTAA
CAAGCCAACCAAGATCTTATGAATTTTAGGTCTGATTTTGAATAATACTAAAGATTTTAG
TTAGATCTTGAATTTGTCAATATGCTAGCCAATCCATATTACATTTTATGTATAATTAAA
TATTACATTTTAGACAAATAAAATATTTAGATTTTTTTAAATAGAACTTTAAGAATATGA
TTATTTTTCAAACGAAAGATTTTAAAATTATTTGAAGTATTTATCATATTTCAAACAACC
TGAATATTTCAAATTCGTTAAGTAAGCTTTACTATTTAATACAAATCATTTCTAAGCAAT
TTTTTAAAAAAAGGTATCCACTAGGCATAAAAATGCTTGATTTAATTTAACAAGACAAAT
TTATTGAAAACTTGAGTAATAACGGAATTGAATTAGCAAATAAAATGAATATTCAAAATA
CTTATACTAAATAATTTTTAAATTATTTAGCAAAAAAATCTAGCTTGTAAAAAGATATTA
AAAAAGAAGAAAATTGA