Identifiers and Description

Gene Model Identifier

TTHERM_01029960

Standard Name

MDH4 (malate dehydrogenase 4)

Aliases

PreTt10826 | 204.m00055

Description

MDH4 cytoplasmic and cytosolic malate dehydrogenase family protein; malate dehydrogenase family protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• oxidoreductase activity (IEA) | GO:0016491

Biological Process

• oxidation-reduction process (IEA) | GO:0055114

Domains

• ( TIGR01759 ) malate dehydrogenase
• ( TIGR01756 ) lactate dehydrogenase
• ( TIGR01758 ) malate dehydrogenase, NAD-dependent
• ( TIGR01763 ) malate dehydrogenase, NAD-dependent
• ( TIGR01772 ) malate dehydrogenase, NAD-dependent
• ( TIGR01757 ) malate dehydrogenase, NADP-dependent
• ( PF00056 ) lactate/malate dehydrogenase, NAD binding domain
• ( PF02866 ) lactate/malate dehydrogenase, alpha/beta C-terminal domain

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.1%

TetraMine Data

TTHERM_01029960

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_10494.1	9.997093137033517e-262	malate dehydrogenase (337 aa)
DictyBase	DDB_G0280255	6.996525358388811e-93	mdhC on chromosome: 3 position 3171359 to 3172577
Oxytricha	Contig22377.0.g62	1.0002434920975502e-91	lactate/malate dehydrogenase, alpha/beta C-terminal domain
WormBase	WBGene00018491	4.999773105566236e-81	locus:mdh-1 Malate dehydroge nase status:Confirmed UniP rot:Q9UAV5 protein_id:CCD713 16.1
Stentor Coeruleus	SteCoe_18880	2.506567475899953e-46
SGD	YKL085W	0.0000000000002999981760818895	MDH1 Mitochondrial malate dehy drogenase, catalyzes interconv ersion of malate and oxaloacet ate; involved in the tricarbox ylic acid (TCA) cycle; phospho rylated

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_01029960(coding)
ATGATAAAAGAATACTTTTTTTAGAATTATTATTTATTTTAATTTATTCCAAAAAAAACA
TAAATAAATGGTATGATTTAAAAATAATTATTTTTGGTAGAATATGTTAGATAGGAAGGA
TATAAAATTTTTATTATTTTATATGCAAATATGCAACCATCATTTTTCTTTAGAAATTAA
GATAGCATAAATGTTAAGCACTTTAGACATATAAAGCATGCATACGCATATTTACATACA
GGATGTGTCTATTTATAATCCGTCAAAGGATTAGCACCAACAAAGATAGAACGAGTCATT
TAGGTTTAACGAGAATCATATTATGATTAAGTCATCTATCATGATCCTAATTAAAAATCA
AATAAAAAAGTGATCAATTAAATTAGTAAAGATAAAAGAAAAAATAAATAAACAAATATC
AGGATTTACTAAAAAATTAAAAAGGAAAGAAAATTAGTTTAACTTTTACTTTTTGATAAT
TTAATTTCTGGTACTTAGTTATTTTTAGAAATAAAAGAAAAAAATAATTAATTAATTTGC
AAAAACATTTAAAAGAAATTAAAAGTATTTATCATTTTTAAAAAAAATATAAAACATATT
TTAGAAGTTATGGAGAATAAAGCAGTTATTAATGTTTGTATTACAGGCGCTGCTGGTAAT
ATTGCATACGCCTTGTATTCTATATTGTGCACTGGCCAAATATTTGGGTCTAATCAAAAA
ATGAACTTAAAGCTTTTAGATATTGAATCTCAAGCAAAGGGTCTTTAAGGAGTTGCATTA
GAATTAGAAGATTGCGCCTATGCCCTCGTTAATTCGATAGAGTACGGTTTTGACCCCGAA
GTACTTTTCAAAGATATGGATGTTGGCATTTTCCTCGGAGGGTAATCAAGAAGACCTGGT
ATGGAAAGAGTTGATTTACTTTAAGTAAATAACAGAATTTTCAAGATCTAGGGTAAAGCT
TTGAATAAAGTAGCTAAGCCAAGCACTAAGATTCTAGTAATCGCAAATCCAGTAAACACA
AATTGCTTAACTTTGATTCAAAATTGTCCTAACATTCCTAAAGAAAATTTCACTTGCTTG
ACAAGACTTGACCACAATAGAGCAATAGCATAATTAGCAATCAAAGCAAAAGTACCTGTT
ACCGAAGTTAAAAATGTTATTCTATGGGGTAACCATAGTTTAACTATGTATCCAGATCAC
AATCATGCACACATTGAAGGTCAACCAGCAGTAGATATATATGAAGAGGAATGGATTAAG
AATACTTTCATTCCTAAAGTTTAAAAAAGGGGAGGAGAAGTTCTAAATTTGAGATAGAAC
TCCTCAGTTATGAGTGCTGCAATTGCTATTCGTGACCACTTAGTTAATTGGATTTATGGA
ACTCCTGAAGGATAGTTCGTATCTATGGGTGTTTACACTGACGGAAGCTTCTATGATATT
CCCGCAGATTTTGTTTTCTCAGTTCCAGTTAAGTGCAAAGACTTTAAATACGAAGTTGTT
AAGGATTTGACTATTAGCTAGTTTTCAAGATAAAAAATTAACATCAGTTTGAGAGAATTG
TAAGATGAGAAAGAAGAAGCTAACTGCTACGACGATGATGCTGAAGACGAATCTGAAGAG
TGA

>TTHERM_01029960(protein)
MIKEYFFQNYYLFQFIPKKTQINGMIQKQLFLVEYVRQEGYKIFIILYANMQPSFFFRNQ
DSINVKHFRHIKHAYAYLHTGCVYLQSVKGLAPTKIERVIQVQRESYYDQVIYHDPNQKS
NKKVINQISKDKRKNKQTNIRIYQKIKKERKLVQLLLFDNLISGTQLFLEIKEKNNQLIC
KNIQKKLKVFIIFKKNIKHILEVMENKAVINVCITGAAGNIAYALYSILCTGQIFGSNQK
MNLKLLDIESQAKGLQGVALELEDCAYALVNSIEYGFDPEVLFKDMDVGIFLGGQSRRPG
MERVDLLQVNNRIFKIQGKALNKVAKPSTKILVIANPVNTNCLTLIQNCPNIPKENFTCL
TRLDHNRAIAQLAIKAKVPVTEVKNVILWGNHSLTMYPDHNHAHIEGQPAVDIYEEEWIK
NTFIPKVQKRGGEVLNLRQNSSVMSAAIAIRDHLVNWIYGTPEGQFVSMGVYTDGSFYDI
PADFVFSVPVKCKDFKYEVVKDLTISQFSRQKINISLRELQDEKEEANCYDDDAEDESEE

>TTHERM_01029960(gene)
ATGATAAAAGAATACTTTTTTTAGAATTATTATTTATTTTAATTTATTCCAAAAAAAACA
TAAATAAATGGTATGATTTAAAAATAATTATTTTTGGTAGAATATGTTAGATAGGAAGGA
TATAAAATTTTTATTATTTTATATGCAAATATGCAACCATCATTTTTCTTTAGAAATTAA
GATAGCATAAATGTTAAGCACTTTAGACATATAAAGCATGCATACGCATATTTACATACA
GGATGTGTCTATTTATAATCCGTCAAAGGATTAGCACCAACAAAGATAGAACGAGTCATT
TAGGTTTAACGAGAATCATATTATGATTAAGTCATCTATCATGATCCTAATTAAAAATCA
AATAAAAAAGTGATCAATTAAATTAGTAAAGATAAAAGAAAAAATAAATAAACAAATATC
AGGATTTACTAAAAAATTAAAAAGGAAAGAAAATTAGTTTAACTTTTACTTTTTGATAAT
TTAATTTCTGGTACTTAGTTATTTTTAGAAATAAAAGAAAAAAATAATTAATTAATTTGC
AAAAACATTTAAAAGAAATTAAAAGTATTTATCATTTTTAAAAAAAATATAAAACATATT
TTAGAAGTTATGGAGAATAAAGCAGTTATTAATGTTTGTATTACAGGCGCTGCTGGTAAT
ATTGCATACGCCTTGTATTCTATATTGTGCACTGGCCAAATATTTGGGTCTAATCAAAAA
ATGAACTTAAAGCTTTTAGATATTGAATCTCAAGCAAAGGGTCTTTAAGGAGTTGCATTA
GAATTAGAAGATTGCGCCTATGCCCTCGTTAATTCGATAGAGTACGGTTTTGACCCCGAA
GTACTTTTCAAAGATATGGATGTTGGCATTTTCCTCGGAGGGTAATCAAGAAGACCTGGT
ATGGAAAGAGTTGATTTACTTTAAGTAAATAACAGAATTTTCAAGATCTAGGGTAAAGCT
TTGAATAAAGTAGCTAAGCCAAGCACTAAGATTCTAGTAATCGCAAATCCAGTAAGAAAA
AAAATATATTTTTATAGAAAACTTAGATAATTACCAACTTAATTATGCACGTTAGTTAAA
GAATCAGATTGGTTAGTTTAAGTATCAATTTGAAATGGTAGAGATAAAAATTTGATTGAT
TTGCTAATGTGCTGATTGACTAATAAGCAGTCAATCTATTTTGTTTATGACAAAATTGAA
ATACTTTTATAAGTTTTGATAATCTATTACAATTATGAATATCAACATTATTAATAAGCA
TTCAATTAATGTAAAAATAATCTTATTATCTGTTTTATAATAAAAAGGTAAACACAAATT
GCTTAACTTTGATTCAAAATTGTCCTAACATTCCTAAAGAAAATTTCACTTGCTTGACAA
GACTTGACCACAATAGAGCAATAGCATAATTAGCAATCAAAGCAAAAGTACCTGTTACCG
AAGTTAAAAATGTTATTCTATGGGGTAATTAATTTAAATGTCAAAAATCAAGAGGAATTG
GCATTCTATTTAAAGAATTTTAATATCATTTTAATAATTTACATAGGTAACCATAGTTTA
ACTATGTATCCAGATCACAATCATGCACACATTGAAGGTCAACCAGCAGTAGATATATAT
GAAGAGGAATGGATTAAGAATACTTTCATTCCTAAAGTTTAAAAAAGGGGAGGAGAAGTT
CTAAATTTGAGATAGAACTCCTCAGTTATGAGTGCTGCAATTGCTATTCGTGACCACTTA
GTTAATTGGATTTATGGAACTCCTGAAGGATAGTTCGTATCTATGGGTGTTTACACTGAC
GGAAGCTTCTATGATATTCCCGCAGATTTTGTTTTCTCAGTTCCAGTTAAGTGCAAAGAC
TTTAAATACGAAGTTGTTAAGGATTTGACTATTAGCTAGTTTTCAAGATAAAAAATTAAC
ATCAGTTTGAGAGAATTGTAAGATGAGAAAGAAGAAGCTAACTGCTACGACGATGATGCT
GAAGACGAATCTGAAGAGTGA