Identifiers and Description

Gene Model Identifier

TTHERM_00030190

Standard Name

MDH1 (Malate DeHydrogenase 1)

Aliases

PreTt14250 | 2.m02347 | 3825.m02637

Description

MDH1 cytoplasmic and cytosolic malate dehydrogenase family protein; Malate dehydrogenase family protein; converts malate to oxaloacetate in TCA cycle

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• oxidoreductase activity (IEA) | GO:0016491

Biological Process

• oxidation-reduction process (IEA) | GO:0055114

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 11.2%

TetraMine Data

TTHERM_00030190

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_00809.1	9.997093137033517e-262	malate dehydrogenase (348 aa)
Oxytricha	Contig22377.0.g62	4.9990774786573115e-144	lactate/malate dehydrogenase, alpha/beta C-terminal domain
DictyBase	DDB_G0292600	1.999489510516749e-128	mdhB on chromosome: 6 position 1826095 to 1827141
WormBase	WBGene00018491	2.998957050488393e-103	locus:mdh-1 Malate dehydroge nase status:Confirmed UniP rot:Q9UAV5 protein_id:CCD713 16.1
Stentor Coeruleus	SteCoe_5398	9.462629465836378e-57
SGD	YKL085W	0.000000019990673443141236	MDH1 Mitochondrial malate dehy drogenase, catalyzes interconv ersion of malate and oxaloacet ate; involved in the tricarbox ylic acid (TCA) cycle; phospho rylated

General Information

No Data fetched for General Information

Associated Literature

1. Ref:SUPR000168
2. Ref:SUPR000224

Sequences

>TTHERM_00030190(coding)
ATGATCTCTAAGCTCTTCTAAAATACTGCTAAGTCCCTCACTGCTGTCAACAGCGCTTCC
TTCAGTCACCACCACCACAAGGCTCCCGTCAGAGTTGCTGTCACTGGTGCTGCTGGTAAC
ATCGGTTATGCTCTCGTCTTCAGAATTGCTTCTGGTGAATTATTAGGTAAGGACCAACCC
GTCATCCTTTAATTAATCGAACTCCCCCATGCTTAAAATGCTCTTAAGGGTGTTGCTATG
GAATTGAACGATTGTGCTTTCCCCTTGTTACGTGACATCGTCACCACTGACAGCCAATCT
GTTGGTTTCAAGAATGCTGACTACGCTTTGTTGGTTGGTTCTAAGCCCAGAGGTAAAGGT
CAAGAAAGAGCTGATCTTATCAAGGATAATGGTAAGATTTTCGTCGACACTGGTAAGGCT
ATTAACGACAATGCCTCCAGAGACTGCAAGGTTTTGGTTGTTGGTAACCCCGCTAACACT
AACTGTTTAATCGCTGCTCACTATGCTAAGGATATCCCTAAAGAAAACTTCACTGCCATG
ACCAGATTAGATCACGACCGTGCCTTATACTAACTCGCCTCCAAGACTGGATCTTAAGTC
ACTGACATTAAAAAGCTCTGCATCTGGGGTAACCACTCTCCTACCATGTATCCCGATTTG
ACCAACACCACCGTTCACAATAAGCTTGTTGCTCCCACTTTGGACCATGCTTGGATTGAT
ACTTTCTTCAATCCTAAGGTTGGTAAGAGAGGTGCTGAAATTATTGATGCCAGAGGTTCT
TCTTCTGCTGCTTCTGCTGCCAACGCTGCTATTAACCACGTTAGAGACTGGGCTTTGGGT
AGTGAAGATTGGGTTTCTATGGGTGTTCCCTCTGATGGTTCTTACAACGTTCCCAAGGGT
TTGGTCTTCTCCTTCCCCGTCACCACCAAGAACGGTAAGTACTCCATCGTTCAAGGTCTT
AAGATTAGTGAATACTCTCAAAAGAAGATTGATATCACTACTAAGGAACTTCTTGAAGAA
AGAGCTTGCGTTGAACACTTACTCAAGTGA

>TTHERM_00030190(protein)
MISKLFQNTAKSLTAVNSASFSHHHHKAPVRVAVTGAAGNIGYALVFRIASGELLGKDQP
VILQLIELPHAQNALKGVAMELNDCAFPLLRDIVTTDSQSVGFKNADYALLVGSKPRGKG
QERADLIKDNGKIFVDTGKAINDNASRDCKVLVVGNPANTNCLIAAHYAKDIPKENFTAM
TRLDHDRALYQLASKTGSQVTDIKKLCIWGNHSPTMYPDLTNTTVHNKLVAPTLDHAWID
TFFNPKVGKRGAEIIDARGSSSAASAANAAINHVRDWALGSEDWVSMGVPSDGSYNVPKG
LVFSFPVTTKNGKYSIVQGLKISEYSQKKIDITTKELLEERACVEHLLK

>TTHERM_00030190(gene)
ATGATCTCTAAGCTCTTCTAAAATACTGCTAAGTCCCTCACTGCTGTCAACAGCGCTTCC
TTCAGTCACGTAATTTAACACTATCCCTTATCTATTAACCCACTCACATTGAATTGAAAG
ACTTTTTCATCCAATTAAAGCATAAATATCCATTTTAGCTTTAACAACCATATTTTAATT
TGTAAAATGCTAATTAACTCATTTCTTAAATAAAACTTTAGCACCACCACAAGGCTCCCG
TCAGAGTTGCTGTCACTGGTGCTGCTGGTAACATCGGTTATGCTCTCGTCTTCAGAATTG
CTTCTGGTGAATTATTAGGTAAGGACCAACCCGTCATCCTTTAATTAATCGAACTCCCCC
ATGCTTAAAATGCTCTTAAGGTAAACAAAACAACTTCTTTCAGCTTTGATACTTTATTTA
TAAGCAGCTTAAATGTATAAAGTAGTTGCTTTCTACTCTATTTATTAGAGTATATGAAGC
TTATTTTATTCTGAACAAAAGCTGGATTTATTTGATTATATTTATTCTATATACTAGTTT
AACAATACTTTGTTTTAAATTTAAAGGGTGTTGCTATGGAATTGAACGATTGTGCTTTCC
CCTTGTTACGTGACATCGTCACCACTGACAGCCAATCTGTTGGTTTCAAGAATGCTGACT
ACGCTTTGTTGGTTGGTTCTAAGCCCAGAGGTAAAGGTCAAGAAAGAGCTGATCTTATCA
AGGATAATGGTAAGATTTTCGTCGACACTGGTAAGGTAAGGATAAAACTTTTAAAGATAT
TTTATTAGTACGATAAGGAATAAATGAATAATGAGTAGAAAAGAAATTTCATATAAAATT
TAAGAGTTGTTAGTAGAACATTCAGCATTAATAAAAGCTTTATCAAAATAAGCTTTCGCT
TGTTTAGCAGAAATAATAAATTAATAGGAATAAAAAATTTATATCTAGAAATATACTCAA
ACATATCAATAAATAAAGCAAATAACACAAATAGAATAATCTCGTTTTTTCTATTAATTT
ATTTCTTGGTTCTCCTACTACTTGTTATTCAAATATTACCTTAAATTAATTTTTAAAAAT
CTAATAGCTAGAAGCGAATTAATTTTATTTGTTTTTTAATAGGCTATTAACGACAATGCC
TCCAGAGACTGCAAGGTTTTGGTTGTTGGTAACCCCGCTAACACTAACTGTTTAATCGCT
GCTCACTATGCTAAGGATATCCCTAAAGAAAACTTCACTGCCATGACCAGATTAGATCAC
GACCGTGCCTTATACTAACTCGCCTCCAAGACTGGATCTTAAGTCACTGACATTAAAAAG
CTCTGCATCTGGGGTAACCACTCTCCTACCATGTATCCCGATTTGACCAACACCACCGTT
CACAATAAGCTTGTTGCTCCCACTTTGGACCATGCTTGGATTGATACTTTCTTCAATCCT
AAGGTTGGTAAGAGAGGTGCTGAAATTATTGATGCCAGAGGTTCTTCTTCTGCTGCTTCT
GCTGCCAACGCTGCTATTAACCACGTTAGAGACTGGGCTTTGGGTAGTGAAGATTGGGTT
TCTATGGGTGTTCCCTCTGATGGTTCTTACAACGTTCCCAAGGGTTTGGTCTTCTCCTTC
CCCGTCACCACCAAGAACGGTAAGTACTCCATCGTTCAAGGTCTTAAGATTAGTGAATAC
TCTCAAAAGAAGATTGATATCACTACTAAGGAACTTCTTGAAGAAAGAGCTTGCGTTGAA
CACTTACTCAAGTGA