Identifiers and Description

Gene Model Identifier

TTHERM_00499370

Standard Name

LTL1 (Lia3-like 1)

Aliases

PreTt07980 | 63.m00158 | 3716.m00012

Description

A Lia3-like protein that regulates DNA elimination boundaries

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF07453 ) NUMOD1 domain
• ( PF00376 ) transcriptional regulator, MerR family
• ( TIGR01764 ) DNA binding domain, excisionase family

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.8%

TetraMine Data

TTHERM_00499370

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_09696.1	9.997093137033517e-262	hypothetical protein (412 aa)

General Information

No Data fetched for General Information

Associated Literature

1. Ref:31194876: Jaspan VN, Taye ME, Carle CM, Chung JJ, Chalker DL (2019) Boundaries of eliminated heterochromatin of Tetrahymena are positioned by the DNA-binding protein Ltl1. Nucleic acids research ( ):
2. Ref:26950070: Carle CM, Zaher HS, Chalker DL (2016) A Parallel G Quadruplex-Binding Protein Regulates the Boundaries of DNA Elimination Events of Tetrahymena thermophila. PLoS genetics 12(3):e1005842
3. Ref:26688337: Kataoka K, Mochizuki K (2015) Phosphorylation of an HP1-like Protein Regulates Heterochromatin Body Assembly for DNA Elimination. Developmental cell 35(6):775-88

Sequences

>TTHERM_00499370(coding)
ATGAATTTAACTTCTTAGCCTATAAACATAGAGGCAAAAAGTCTCATAGTCTCATTAAAG
TAAAGGGAATATACTAATGAAGAGATAAATACTATTCTTATCTAACTCGGATATGAGTCG
ACACCAAGAATAGTCTAGAATTAATGGAGAATTTATGAAGAAAGAAAGTAATCTAAGTAA
AAAAAAGAAACAAAGAGAGCTCCTCCTTTTATGCTTAACTCTGAAAAAATAAAGCAAATG
ACCTATCTTTTCCTTAATAATTAAGAAATGACAGTAAATAAGGCGTCGAAATTATTTGGA
ATAGGCAAGTAACAAATTAGGAGATATTTAATTTAGTTTGGTATTGGCTGTACGAAGGGC
AAAGGATAAAAATTTGAAAGATACACTTTTAAAAAATTTAACAAAAAGAAATTGACTTCT
TCTGAAATTGAAGAAATAGAAAACGAAGAGTTATAAAAGCGATTAAATCGTCCTATGATT
CAAGAACCAAGTCCGATAGACCCTTAATCGCCTCCCATTTGGAAAAAGATTGAAATGAGA
ATTATTTTCCCTAAAATAAGATATGGCTAAGTTCATTAGTGGGAAAGATATTATGATAGG
CTAATTAATGAAGTTAAACTAAATAGTTTGAAATTTCTAGATTTTAAAAGGGGAGAAAAA
TTTACTGGTAAAGGCTGCTATATTTACATTTTGTCTGAATATGATTAAAATGTTTTCTTG
GATAATTTTACTTTAGAAAAGTTCTTAGAAACTTCTTTACCAGAGGATTTTTTTGCTGGG
AATTGCCTTAATACAAATAAAATTAGAATTTTTGATTACCCATATATTCCATAAAATTTA
CCTCAGGAGGATATCATTAACCTTAATGATCCAAATATAGAAGAAATATTTAAAAAAGTT
AATAATAAAATCAAAAACATGAATGAATAAGAATAACAACAATTAAACAGTTTAGCACTA
TAAATTCATTAATAATATTAAAAAGATGCAAATAAGTAATTTAATCCAATGAATAGCGAA
TCTTCAATGAGCGAAGAGGAGCCTGATTAAGAATCTAAAAATATTTTATAAATGAATTTA
CAAAAGAAAATTGCAAAAAGCAAATTCTTGCCTAATGTTTAAGGAATGGATATTGATGAA
TAAAATTAGCTATTGTTTAAAGAAATGGATTAGTTAGAAAATAATTAAGATTATTAACTA
GACAACACTCAAGATAACTAATTTTTTGCAAAATAAGAAGACGTTTTAAATTGA

>TTHERM_00499370(protein)
MNLTSQPINIEAKSLIVSLKQREYTNEEINTILIQLGYESTPRIVQNQWRIYEERKQSKQ
KKETKRAPPFMLNSEKIKQMTYLFLNNQEMTVNKASKLFGIGKQQIRRYLIQFGIGCTKG
KGQKFERYTFKKFNKKKLTSSEIEEIENEELQKRLNRPMIQEPSPIDPQSPPIWKKIEMR
IIFPKIRYGQVHQWERYYDRLINEVKLNSLKFLDFKRGEKFTGKGCYIYILSEYDQNVFL
DNFTLEKFLETSLPEDFFAGNCLNTNKIRIFDYPYIPQNLPQEDIINLNDPNIEEIFKKV
NNKIKNMNEQEQQQLNSLALQIHQQYQKDANKQFNPMNSESSMSEEEPDQESKNILQMNL
QKKIAKSKFLPNVQGMDIDEQNQLLFKEMDQLENNQDYQLDNTQDNQFFAKQEDVLN

>TTHERM_00499370(gene)
ATGAATTTAACTTCTTAGCCTATAAACATAGAGGCAAAAAGTCTCATAGTCTCATTAAAG
TAAAGGGAATATACTAATGAAGAGATAAATACTATTCTTATCTAACTCGGATATGAGTCG
ACACCAAGAATAGTCTAGAATTAATGGAGAATTTATGAAGAAAGAAAGTAATCTAAGTAA
AAAAAAGAAACAAAGAGAGCTCCTCCTTTTATGCTTAACTCTGAAAAAATAAAGCAAATG
ACCTATCTTTTCCTTAATAATTAAGAAATGACAGTAAATAAGGCGTCGAAATTATTTGGA
ATAGGCAAGTAACAAATTAGGAGATATTTAATTTAGTTTGGTATTGGCTGTACGAAGGTA
TTTATTTATCGATCAACATAAAAATTTAATAACTTTAATATAATTATTGATTTTATTGTT
AAAGCTATTTTATTAATTATTAAAAGGGCAAAGGATAAAAATTTGAAAGATACACTTTTA
AAAAATTTAACAAAAAGAAATTGACTTCTTCTGAAATTGAAGAAATAGAAAACGAAGAGT
TATAAAAGCGATTAAATCGTCCTATGATTCAAGAACCAAGTCCGATAGACCCTTAATCGC
CTCCCATTTGGTAATTTTTTATATTTGAAAATTTCAGGTAATTTATAGTAAACAAAATCA
TAGGAAAAAGATTGAAATGAGAATTATTTTCCCTAAAATAAGATATGGCTAAGTTCATTA
GTGGGAAAGATATTATGATAGGCTAATTAATGAAGTTAAACTAAATAGTTTGAAATTTCT
AGATTTTAAAAGGGGAGAAAAATTTACTGGTAAAGGCTGCTATATTTACATTTTGTCTGA
ATATGATTAAAATGTTTTCTTGGATAATTTTACTTTAGAAAAGTTCTTAGAAACTTCTTT
ACCAGAGGATTTTTTTGCTGGGAATTGCCTTAATACAAATAAAATTAGAATTTTTGATTA
CCCATATATTCCATAAAATTTACCTCAGGAGGATATCATTAACCTTAATGATCCAAATAT
AGAAGAAATATTTAAAAAAGTTAATAATAAAATCAAAAACATGAATGAATAAGAATAACA
ACAATTAAACAGTTTAGCACTATAAATTCATTAATAATATTAAAAAGATGCAAATAAGTA
ATTTAATCCAATGAATAGCGAATCTTCAATGAGCGAAGAGGAGCCTGATTAAGAATCTAA
AAATATTTTATAAATGAATTTACAAAAGAAAATTGCAAAAAGCAAATTCTTGCCTAATGT
TTAAGGAATGGATATTGATGAATAAAATTAGCTATTGTTTAAAGAAATGGATTAGTTAGA
AAATAATTAAGATTATTAACTAGACAACACTCAAGATAACTAATTTTTTGCAAAATAAGA
AGACGTTTTAAATTGA