Identifiers and Description

Gene Model Identifier

TTHERM_00068140

Standard Name

LSC1 (Ligase of Succinyl-CoA  )

Aliases

PreTt13203 | 4.m00602 | 3707.m00239

Description

Alpha subunit of succinyl-CoA ligase

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• catalytic activity (IEA) | GO:0003824

Biological Process

• metabolic process (IEA) | GO:0008152

Domains

• ( PF00549 ) CoA-ligase
• ( PF02629 ) CoA binding domain
• ( TIGR01019 ) succinate-CoA ligase, alpha subunit
• ( PF01113 ) Dihydrodipicolinate reductase, N-terminus
• ( PF01408 ) Oxidoreductase family, NAD-binding Rossmann fold
• ( TIGR02717 ) acetyl coenzyme A synthetase (ADP

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 11.4%

TetraMine Data

TTHERM_00068140

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_02112.1	9.997093137033517e-262	succinyl-CoA synthetase, alpha subunit protein (311 aa)
DictyBase	DDB_G0289325	7.998494937295598e-144	scsA on chromosome: 5 position 2650999 to 2652299
Oxytricha	Contig13094.0.g105	5.000301007691871e-141	CoA binding domain
WormBase	WBGene00007350	5.997858334163121e-134	locus:sucl-1 Probable succin yl-CoA ligase [ADP/GDP-forming ] subunit alpha, mitochondrial status:Confirmed UniProt: P53596 protein_id:CAA94107.1
SGD	YOR142W	6.999054974866289e-109	LSC1 Alpha subunit of succinyl -CoA ligase, which is a mitoch ondrial enzyme of the TCA cycl e that catalyzes the nucleotid e-dependent conversion of succ inyl-CoA to succinate; phospho rylated
Stentor Coeruleus	SteCoe_35214	1.7785284761271306e-68

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00068140(coding)
ATGTTGTCAAAGACTATTTCCAATTTCTTCAGCTCTACCAAGCCCTACGTTTGGATTAAC
AAGCACACTAAGGTTATTTGCCAAGGTATCACTGGTAACCAAGGTACTTTACACACTCAA
CAAGCTCTTGAATACGGTACTAAGATGGTTGGTGGTGTCAATCCTGCTAAGGCTGGTCAA
ACCCACTTGGGCTTACCCGTTTTCAAGAACTGCCAAGAAGCCAAGAAAGTCACCGGTTGT
GATGCTTCCGTTATCTACGTTCCTCCCCCTCATGCTGCTAAGGCTATTATGGAAGCTATT
GAAGCTGAAATTCCCTTGGTCGTTGTCATCACCGATGGTATCCCATAACACGACATGGTC
AAGGTTAAGCACGCTCTTAGACAACAAAAGATTACCAGAATTATTGGTCCCAATTGCCCT
GGTATCATTAAGCCCAACGAATGTAAGATTGGTATTATGCCCGGTTACATTCACAAGCCT
GGTAAAATCGGTATCGTCTCAAGATCTGGTACTTTGACTTACGAAGCTGTTGACTAAACT
ACTAAGGCTGGTTTGGGTCAATCTACCGTCGTTGGTATTGGTGGTGATCCTTTCAACGGT
ACCAATTTCATCGATGTCCTCGAAAGATTCGTTGAAGATCCCGAAACTGAAGGTATTTTA
TTAATTGGTGAAATCGGTGGTGAAGCTGAAGAACAAGCTGCTGCCTGGTTGAAGGCTAAC
AATAAAACCAACAAGCCCGTTGTTTCTTTCATTGCTGGTGTTACTGCTCCTCCTGAGAGA
AGAATGGGTCACGCTGGTGCTATCGTTTCTGGTGGTAAGGGTTCTGCCACTGAAAAGATC
AAGGCTTTAGAATCTGCTGGCATTAAGGTCTGCAGATCTCCTGCCACCTTAGGTCAAGAA
ATGCTCAACCTCATGAAGGTCCATAAGAACTGA

>TTHERM_00068140(protein)
MLSKTISNFFSSTKPYVWINKHTKVICQGITGNQGTLHTQQALEYGTKMVGGVNPAKAGQ
THLGLPVFKNCQEAKKVTGCDASVIYVPPPHAAKAIMEAIEAEIPLVVVITDGIPQHDMV
KVKHALRQQKITRIIGPNCPGIIKPNECKIGIMPGYIHKPGKIGIVSRSGTLTYEAVDQT
TKAGLGQSTVVGIGGDPFNGTNFIDVLERFVEDPETEGILLIGEIGGEAEEQAAAWLKAN
NKTNKPVVSFIAGVTAPPERRMGHAGAIVSGGKGSATEKIKALESAGIKVCRSPATLGQE
MLNLMKVHKN

>TTHERM_00068140(gene)
ATGTTGTCAAAGACTATTTCCAATTTCTTCAGCTCTACCAAGCCCTACGTTTGGATTAAC
AAGCACACTAAGGTTATTTGCCAAGGTATCACTGGTAACCAAGTAAGAATTGATATCAAT
TTCTAAATTTTGAGCTATTTTCATTTGTTCTCCAGCTCGCTTTTGGATTTTAGCAAATGC
TCTCCCTTTCCTTCATTTTCTCTATTAGTCATTTTAAACCATATCCTCTTCAAATGAAAA
TATTTCTTCAGTTTGAAAGTTTCAAAGCAAATAGACCTTAAAAAGTAAAATAGCCATGAA
AATAAAAATGATTATCAAGTATCAAAAAATACAAATTAAGCAGTCAAATTGTAAAAAATC
GAAGCAAATAAATAAAGTCCAATTCAAATTTCAGCAAAAGAGCATTAAAATCGTAGATAA
GGGAGTATTAAAACACAGAAATTATTTGAATTATTACTGCAAAACAAAATTCAGTCAAAT
CCAAAACAAGCTACATATTAGAAGAAATCTCTTTTATAAATCTCATTTGAATAAGCAAAA
AAAGAACTTTAAAAAGAAGGGAATCAACAATCGTATTTCCAAGGAAACAGATATATCTAT
CTTATTTATTCATTTGAAGCGAGAGAATAAATTAGAAAAATTTAGAGATATTTATTTATT
AAAACTCCTTTTATTAAAATTTAGGGTACTTTACACACTCAACAAGCTCTTGAATACGGT
ACTAAGATGGTTGGTGGTGTCAATCCTGCTAAGGCTGGTCAAACCCACTTGGGCTTACCC
GTTTTCAAGAACTGCCAAGAAGCCAAGAAAGTCACCGGTTGTGATGCTTCCGTTATCTAC
GTTCCTCCCCCTCATGCTGCTAAGGCTATTATGGAAGCTATTGAAGCTGAAATTCCCTTG
GTCGTTGTCATCACCGATGGTATCCCATAACACGACATGGTCAAGGTTAAGCACGCTCTT
AGACAACAAAAGATTACCAGAATTATTGGTCCCAATTGCCCTGGTATCATTAAGCCCAAC
GAATGTAAGATTGGTATTATGCCCGGTTACATTCACAAGCCTGGTAAAATCGGTAAGCAA
ATTACTCTTAAATATTCACTCAAGCTATATTTTTAATTACCTTTCAGTTTGCACTTTGAT
TCTAAAAAAGAGAATGCTTAAGAAGTTTCGCATATTAATAGCTAACTGCATTTTTAATAA
TTCAAAATAATCTGAATATTCTGCCTTAATTTTATTAAATTAATTGAAGGAAAGAACTTA
AATAGATTAAATTGCTTAATAAAAAGTATCTTAAAAAAGACTATATCGTTTTTCTTTTTT
ACTTAAGATGTGTAGAAAACAATAGAACTATTTATATCTTTAAAAGAATACAAAAGAACA
TTATTTTTTAGACAAAAATTCAAAATAAAATAATAATAACAAATTAAATTAATAGATAAA
TAAATATACAAAAAACATCAAGCATATCTTAAATTTATTTATTTATTTTGTAGATAAGGT
GCAGATTGAAATAATTAAAATGAATGATTAAATTTAGTTTCTTCCTTACATAATTCTTAT
ATTTTATATAAAAGGTATCGTCTCAAGATCTGGTACTTTGACTTACGAAGCTGTTGACTA
AACTACTAAGGCTGGTTTGGGTCAATCTACCGTCGTTGGTATTGGTGGTGATCCTTTCAA
CGGTACCAATTTCATCGATGTCCTCGAAAGATTCGTTGAAGATCCCGAAACTGAAGGTAA
AAAAAAATAATAAAATTATATTAATTCAGCTTATTAAAAGATAGCATTATTATTTGGCAA
TAAGATTTAGAATATAGCAAAATTATAGAATATATAATGCTTTTAAAATAAATAATATTG
ATTAAACATATTATTTGTAAATTTACTTAAGAAATACTTTCTTAATAAAATGCTAAAAGA
TTTTACTAATTTTAGATTATTTATTTAAAAATTGTAATTAATTTTGAAAACTTGCTCACT
AATTGTTTTATAAAAAAAGGTATTTTATTAATTGGTGAAATCGGTGGTGAAGCTGAAGAA
CAAGCTGCTGCCTGGTTGAAGGCTAACAATAAAACCAACAAGCCCGTTGTTTCTTTCATT
GCTGGTGTTACTGCTCCTCCTGAGAGAAGAATGGGTCACGCTGGTGCTATCGTTTCTGGT
GGTAAGGGTTCTGCCACTGAAAAGATCAAGGCTTTAGAATCTGCTGGCATTAAGGTCTGC
AGATCTCCTGCCACCTTAGGTCAAGAAATGCTCAACCTCATGAAGGTCCATAAGAACTGA