Identifiers and Description

Gene Model Identifier

TTHERM_00348170

Standard Name

LIG1 (DNA ligase I )

Aliases

PreTt05229 | 36.m00193 | 3703.m00026

Description

LIG1 DNA ligase I ATP-dependent protein; homolog to human LIG1

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• DNA ligase (ATP) activity (IEA) | GO:0003910
• DNA binding (IEA) | GO:0003677

Biological Process

• DNA replication (IEA) | GO:0006260
• DNA recombination (IEA) | GO:0006310
• DNA repair (IEA) | GO:0006281

Domains

• ( TIGR02776 ) DNA ligase D
• ( PF04675 ) DNA ligase N terminus
• ( PF01068 ) ATP-dependent DNA ligase domain
• ( TIGR01725 ) phage protein, HK97 gp10 family
• ( TIGR00574 ) DNA ligase I, ATP-dependent (dnl1)
• ( TIGR02779 ) DNA polymerase LigD, ligase domain
• ( PF01331 ) mRNA capping enzyme, catalytic domain
• ( PF04679 ) ATP dependent DNA ligase C

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.2%

TetraMine Data

TTHERM_00348170

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_09734.1	9.997093137033517e-262	DNA ligase I (816 aa)
Oxytricha	Contig887.1.g61	9.997093137033517e-262	ATP dependent DNA ligase domai n
DictyBase	DDB_G0274493	1.9999565133760522e-166	lig1 on chromosome: 2 position 4400712 to 4404415
SGD	YDL164C	1.0002534232488231e-144	CDC9 DNA ligase found in the n ucleus and mitochondria, an es sential enzyme that joins Okaz aki fragments during DNA repli cation; also acts in nucleotid e excision repair, base excisi on repair, and recombination
WormBase	WBGene00002985	2.0002124324463154e-144	locus:lig-1 DNA ligase 1 s tatus:Partially_confirmed Un iProt:Q27474 protein_id:CAA9 8242.2
Stentor Coeruleus	SteCoe_12774	0.00000000027894680928689246

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00348170(coding)
ATGAAGCAAGGTACCATTAAAAACTTCTTTGGAAATAGCCAAAAGAAAAAGGAAGAATTA
GGTGAAAGCAATTTAGGTTCTGACAAAAAATGTGCTACTCAGTCTCAAAAAGGTGCTGAG
ACAAATGGTTAAAACTCAAAGGAATCCCAATAAAAGCCTGATGAATCAAAATCATAGCAA
GAAGAATCTTAATTAAAAGAAAAACCAAAAGCATAAAAAAGAAGATAAATAATAGATAGC
AGTGATGATGAAGAAGTTCCTTCATTGGCTACGATGTCTATAAGTAATAAGTAAATAAAA
AAAGTGGAAAATGAGAACTAAAAAAATGAGTCTTCTAAATCAGAAACAAAATCATCCACA
GATTCTAGCAATTTGTCGAAATAAATACTTGAAAAACCAAAAAATGAAGATGAAAAATTA
AGCCAATCATCTAAAAAAGCAGCAGAATAATAAGATACAAAAAAGAAACCAACTAATAAT
TTGAGAAAACTTTTGGATAAGCACTTTGACCCTATTGAAGACGCTCCATTCTATAAGGAT
TAAGAAGTCTTGTTTGGTTATTTATGTGATGGATTTGAAAGAGTAAATGAACAGGAAGGT
AAAAATTCAAAGGCTATACAAATTGAAATAATGTCAAAAATTTTCAAGTCGATCATATTA
CTTAATCCTGACTAGGTATATGAAGCTTATATGTTTTGTATTTTAAAGATAGCACCTGAT
TATGAGTCTAATGAGCTTGGTGTGGGTAGGGAAATACTTTAAAAAGCAATTAGTAATTGT
TGTGGTAAATCAGTTACTTAAATCAGAGATAGCCTTAATAAACTTGGTGACTTAGGTAAG
GTTGCGTCCGAAGCCAAATCTACCTAAAAAAACATCACAAATTATTTTTAAAAGCAGGCT
AAAGAAAAGCCTCCTATTACTCTTAATAGAACTTTTAATGATTTGAAAAGTATTGCAGCT
GCTTCAGGAAAGGACTCAACTGCAGAAAGAGAAAGAATTATTATAAAATATATGAATGAA
GCAAAACCAGATGAAGCATGCTATTTTATTAGATTTTTAGAGTAGAATTTGAAAATTGGT
GCTGCTGAAAAAACAATGTAGGCAGCTCTTTCCAAAGCATTCTTTGAAATTGCCCACAAT
ATCAAAAGCAATCACGTTTACACAGAATAATAAAACTAACTTTTAGAAGAATTTAACTTC
AATATCACTAGATGTCTGTGTGAGTTTCCAAACTATTACTAAGTCATTGAGACTTTGAAA
TAAATTGGCAAAGATATTTCTAAATTATTAGATATCTGCAAGATCACGATAGGCGTTCCC
TGCAAGCCTATGCTTGCCAAACCAACAAAATCAATTTAAGTTATTTTGGAAAGATTCAAA
GACATGACTTTTACTTGTGAATACAAGTATGATGGATTGAGAGGTCAAATACACTACGAT
GGAAAAGATGTTACTATTTTTAGCAGAAACCTAGAAAATATGACATAGATGTATCCTGAT
ATTGTAGAATTCATAAAAAAACATGTCAGCTAATCGAAAACTGTTAAAAATTTTATTTTA
GATAGTGAAATTGTAGCTTTTGATAAAAACACCAACAAAATTAGACCTTTCTAATAATTA
GCAACAAGAGGAAGAGTCAATGTCAAATTAGATGAAATTGATATAAAAGTTTGTGTTTTT
ATGTTCGATTTAATATATATCAATGACTAGAGTTTGCTACAAACAACACTTTAAGAAAGA
AGATAAAAAATTTAGGAGTGTTTTGTTCAAGAACCTGGTGAGTTCTGCTTTGCTGAGCAC
ATAAACACTGAAGATGTTGAACAAATTTAAGAATTCTTAGAAAAATCTGTTAAGGTGGGA
TGTGAAGGCTTGATGGTTAAAACTTTAGAAACTAACTCAACTTATGAACCAGCAAAAAGA
TCATTTAAATGGCTTAAACTCAAAAAAGATTATTTAGATAGTGGGTTAGGAGATACACTT
GATTTAGTTCCGATTGCAGCCTTCAAGGGTACAGGTAAAAGAGTTGGATTGTATGGTGCT
TACCTATTAGCTTGCTACAATGAAGATATGGAACGTTATGAAACAATATGTAAAATAGGT
ACAGGATTTTCAGATGAAATCTTAGAAGCATGCTATAAATTCTTCTAAGATAAAATTATA
CCATAGCCATAATCTGATTATTTAACCAAAGATTTTAAAGCAGATGTATGGTTTAAACCT
TCTGTAGTTTGGGAAATTAAGGGAGCAGATTTACAAATATCACCAGTATATACTTGTGCA
ATTAGTGAAACAAATTAAGAAAAAGGTATTGGTCTTAGATTCCCTCGTCTTATCAGAGTT
AGAGATGATAAAGATCCAGTCGATGCTACTTCTCCTTCTTTTATATACGATATATATAAA
CAATAAGCTGTTGTAGCAAATGATTTTGATGATGGTGATGATTTCTATTGA

>TTHERM_00348170(protein)
MKQGTIKNFFGNSQKKKEELGESNLGSDKKCATQSQKGAETNGQNSKESQQKPDESKSQQ
EESQLKEKPKAQKRRQIIDSSDDEEVPSLATMSISNKQIKKVENENQKNESSKSETKSST
DSSNLSKQILEKPKNEDEKLSQSSKKAAEQQDTKKKPTNNLRKLLDKHFDPIEDAPFYKD
QEVLFGYLCDGFERVNEQEGKNSKAIQIEIMSKIFKSIILLNPDQVYEAYMFCILKIAPD
YESNELGVGREILQKAISNCCGKSVTQIRDSLNKLGDLGKVASEAKSTQKNITNYFQKQA
KEKPPITLNRTFNDLKSIAAASGKDSTAERERIIIKYMNEAKPDEACYFIRFLEQNLKIG
AAEKTMQAALSKAFFEIAHNIKSNHVYTEQQNQLLEEFNFNITRCLCEFPNYYQVIETLK
QIGKDISKLLDICKITIGVPCKPMLAKPTKSIQVILERFKDMTFTCEYKYDGLRGQIHYD
GKDVTIFSRNLENMTQMYPDIVEFIKKHVSQSKTVKNFILDSEIVAFDKNTNKIRPFQQL
ATRGRVNVKLDEIDIKVCVFMFDLIYINDQSLLQTTLQERRQKIQECFVQEPGEFCFAEH
INTEDVEQIQEFLEKSVKVGCEGLMVKTLETNSTYEPAKRSFKWLKLKKDYLDSGLGDTL
DLVPIAAFKGTGKRVGLYGAYLLACYNEDMERYETICKIGTGFSDEILEACYKFFQDKII
PQPQSDYLTKDFKADVWFKPSVVWEIKGADLQISPVYTCAISETNQEKGIGLRFPRLIRV
RDDKDPVDATSPSFIYDIYKQQAVVANDFDDGDDFY

>TTHERM_00348170(gene)
ATGAAGCAAGGTACCATTAAAAACTTCTTTGGAAATAGCCAAAAGAAAAAGGAAGAATTA
GGTGAAAGCAATTTAGGTTCTGACAAAAAATGTGCTACTCAGTCTCAAAAAGGTGCTGAG
ACAAATGGTTAAAACTCAAAGGAATCCCAATAAAAGCCTGATGAATCAAAATCATAGCAA
GAAGAATCTTAATTAAAAGAAAAACCAAAAGCATAAAAAAGAAGATAAATAATAGATAGC
AGTGATGATGAAGAAGTTCCTTCATTGGCTACGATGTCTATAAGTAATAAGTAAATAAAA
AAAGTGGAAAATGAGAACTAAAAAAATGAGTCTTCTAAATCAGAAACAAAATCATCCACA
GATTCTAGCAATTTGTCGAAATAAATACTTGAAAAACCAAAAAATGAAGATGAAAAATTA
AGCCAATCATCTAAAAAAGCAGCAGAATAATAAGGTATGTGAAATTTAATCAATTTTTAA
ATATGATTTTTTTTATTTATTCTGTAGATACAAAAAAGAAACCAACTAATAATTTGAGAA
AACTTTTGGATAAGCACTTTGACCCTATTGAAGACGCTCCATTCTATAAGGATTAAGAAG
TCTTGTTTGGTTATTTATGTGATGGATTTGAAAGAGTAAATGAACAGGAAGGTAAAAATT
CAAAGGCTATACAAATTGAAATAATGTCAAAAATTTTCAAGTCGATCATATTACTTAATC
CTGACTAGGTATATGAAGCTTATATGTTTTGTATTTTAAAGATAGCACCTGATTATGAGT
CTAATGAGCTTGGTGTGGGTAGGGAAATACTTTAAAAAGCAATTAGTAATTGTTGTGGTA
AATCAGTTACTTAAATCAGAGATAGCCTTAATAAACTTGGTGACTTAGGTAAGGTTGCGT
CCGAAGCCAAATCTACCTAAAAAAACATCACAAATTATTTTTAAAAGCAGGCTAAAGAAA
AGCCTCCTATTACTCTTAATAGAACTTTTAATGATTTGAAAAGTATTGCAGCTGCTTCAG
GAAAGGTAAACAAACATAATTTATTTATTTATTGAACAACTCATAATTAAATGATTTATA
GGACTCAACTGCAGAAAGAGAAAGAATTATTATAAAATATATGAATGAAGCAAAACCAGA
TGAAGCATGCTATTTTATTAGATTTTTAGAGTAGAATTTGAAAATTGGTGCTGCTGAAAA
AACAATGTAGGCAGCTCTTTCCAAAGCATTCTTTGAAATTGCCCACAATATCAAAAGCAA
TCACGTTTACACAGAATAATAAAACTAACTTTTAGAAGAATTTAACTTCAATATCACTAG
ATGTCTGTGTGAGTTTCCAAACTATTACTAAGTCATTGAGACTTTGAAATAAATTGGCAA
AGATATTTCTAAATTATTAGATATCTGCAAGATCACGATAGGCGTTCCCTGCAAGCCTAT
GCTTGCCAAACCAACAAAATCAATTTAAGTAACAATAAATAAATATATAAATTATAAAGT
ATAATAAATTTACAAATACTTAAAGGTTATTTTGGAAAGATTCAAAGACATGACTTTTAC
TTGTGAATACAAGTATGATGGATTGAGAGGTCAAATACACTACGATGGAAAAGATGTTAC
TATTTTTAGCAGAAACCTAGAAAATATGACATAGATGTATCCTGATATTGTAGAATTCAT
AAAAAAACATGTCAGCTAATCGAAAACTGTTAAAAATTTTATTTTAGATAGTGAAATTGT
AGCTTTTGATAAAAACACCAACAAAATTAGACCTTTCTAATAATTAGCAACAAGAGGAAG
AGTCAATGTCAAATTAGATGAAATTGATATAAAAGTTTGTGTTTTTATGTTCGATTTAAT
ATATATCAATGACTAGAGTTTGCTACAAACAACACTTTAAGAAAGAAGATAAAAAATTTA
GGAGTGTTTTGTTCAAGAACCTGGTGAGTTCTGCTTTGCTGAGCACATAAACACTGAAGA
TGTTGAACAAATTTAAGTAAATTGATAACCAATTAATTATTGAAAAATTAACATCTATTT
TTTTTTTAGGAATTCTTAGAAAAATCTGTTAAGGTGGGATGTGAAGGCTTGATGGTTAAA
ACTTTAGAAACTAACTCAACTTATGAACCAGCAAAAAGATCATTTAAATGGCTTAAACTC
AAAAAAGATTATTTAGATAGTGGGTTAGGAGATACACTTGATTTAGTTCCGATTGCAGCC
TTCAAGGGTACAGGTAAAAGAGTTGGATTGTATGGTGCTTACCTATTAGCTTGCTACAAT
GAAGATATGGAACGTTATGAAACAATATGTAAAATAGGTACAGGATTTTCAGATGAAATC
TTAGAAGCATGCTATAAATTCTTCTAAGATAAAATTATACCATAGCCATAATCTGATTAT
TTAACCAAAGATTTTAAAGCAGATGTATGGTTTAAACCTTCTGTAGTTTGGGAAATTAAG
GGAGCAGATTTACAAATATCACCAGTATATACTTGTGCAATTAGTGAAACAAATTAAGAA
AAAGGTATTGGTCTTAGATTCCCTCGTCTTATCAGAGTTAGAGATGATAAAGATCCAGTC
GATGCTACTTCTCCTTCTTTTATATACGATATATATAAACAATAAGCTGTTGTAGCAAAT
GATTTTGATGATGGTGATGATTTCTATTGA