Gene Model Identifier
TTHERM_00653910
Standard Name
LIA5
Aliases
PreTt12878 | 95.m00124 | 3825.m02531
Description
LIA5 transposase IS4 protein
Genome Browser (Macronucleus)
Genome Browser (Micronucleus)
No Data fetched for Gene Ontology Annotations
Tetrahymena Functional Genomics Database:
Signal Peptide Present?: No
TTHERM_00653910
Fullscreen View
No Data fetched for StockID
(v.2006 protein sequences)
Source Identifier Score Description
Tetrahymena borealis EI9_00713.1 9.997093137033517e-262 hypothetical protein (905 aa)
Paragraph No Gene Name Paragraph Text 115 COI6 ,JMJ1 ,LIA5 ,COI7 Coi6p, its interaction partners Coi7p and Lia5p, and the histone demethylase Jmj1p are crucial for confining the production of small RNAs and the formation of heterochromatin to the eliminated sequences. The loss of Coi6p, Coi7p or Jmj1p causes ectopic DNA elimination.
Ref:28273462 : Suhren JH, Noto T, Kataoka K, Gao S, Liu Y, Mochizuki K (2017) Negative Regulators of an RNAi-Heterochromatin Positive Feedback Loop Safeguard Somatic Genome Integrity in Tetrahymena. Cell reports 18(10):2494-2507Ref:29021213 : Noto T, Mochizuki K (2017) Whats, hows and whys of programmed DNA elimination in Tetrahymena. Open biology 7(10): Ref:28087716 : Cheng CY, Young JM, Lin CG, Chao JL, Malik HS, Yao MC (2016) The piggyBac transposon-derived genes TPB1 and TPB6 mediate essential transposon-like excision during the developmental rearrangement of key genes in Tetrahymena thermophila. Genes & development 30(24):2724-2736Ref:24069402 : Shieh AW, Chalker DL (2013) LIA5 is required for nuclear reorganization and programmed DNA rearrangements occurring during tetrahymena macronuclear differentiation. PloS one 8(9):e75337Ref:17519286 : Yao MC, Yao CH, Halasz LM, Fuller P, Rexer CH, Wang SH, Jain R, Coyne RS, Chalker DL (2007) Identification of novel chromatin-associated proteins involved in programmed genome rearrangements in Tetrahymena. Journal of cell science 120(Pt 12):1978-89
>TTHERM_00653910(coding)ATG GAA TTA GGA GAA GCA GAT TTA CAT ACA TCA CAA TCA ATA GTT TAG GAA GAA GTT CCT ATG CAA CAA GAG GTT AAT ATT CAA GAA GAA TAA AAT TCT TAA TTT GAC AAT GTT TAA TAA CAA AAT CAG AAT GTA GAA GAA TAA CAT TAA ACA AAT AAA AAT AAT TTA ACT TAA AAT GAT TTT AAT GAA TTT CAA TAA TAA AAT ACA AAT GAG CAA GAC TTA CCA AGA AAC GAT CAA ACA TAG GTT TAA CCT CAA TAA AAC TTG TAG GAT GAA AAT AAT TAA GAC TAA ACT ATA CAT TTT ACA GAG TAG CAC TTT CAA CAA CGA GAA AGG GAA TCT AGT GAA ACT CAT GAT ACA AGC AAT TAA GAA TTA GAA TAT TAA ATT AAT TAA AAT ATA AAT GAA AAT AAA TAA GTA CAA AAA GAT AAC TTA AAT GAA GAA ATT ATA TCT TAA AAT AAA GAA GCA CTT GAT GGA CAA GAA GAT TAT CAG AAT TTC AAT AAA AAA GAT TTA CCT GAT AAT AAT AAT AGT AAT GAA TAA CAT AAC TAA GAT TAA GAA AAT ATG AAT TAA ATT GAA AGT TAA GAA GGT TAA AAT TAA TTA GTT TAG ATA GAA GTC AAT GGT TCA GTG AAT AGC CTA TAA GAA AAT AAC TAC ATC TAA GAT GGC ACG TTT ATG GAG TAA GAA CAT TTA AAT GAT AAA ATG CAA TAA TAA TAG GAA TAG GCT GTA AAA GAA GAA ACT GAA GAA AGA GAA GAA ATG TAA GAG GAG AAT TAA CTC CAT GAA AAT TAA GAA AAT ATT AGT ATC AGC TAA TAA AAT TAG TAA GCT CAC AGT GAT ATG TAA ATC GAA GTG TAA GCA AAT TAA ATT AAT TAA TAA GAG AAC CAG TTA GAA TCT TTA AAT GAC AAG GAA GTT GTT AAA GAA GAA AAT AAT TTG CTT TTA AAT ATA CTT TCT GAT GAA AAT AAT AAA AGA TTT CAA AGA CTT CCA CCA GAA TTG TCT CCC AAT ATT TTT TGT CAT TTT TTG GGA GGC AAA TCA TTA CAA TTG ACT AAC ATC AAT GAT TCT AGC AGG CTT TTT ATG TAT TTC TTG GGA ACT AAG ATA TTA AGA TAG CTG CTT AAT AAA GCA AAT GTA AAG CTA AGA GAA ATT TAC AAG AAA TAA AAT GAC GTT AAG GAA TAT ACT ATT GAA GAA ATA CAA GTC TAT TAA GCT TTG AAA ATT TTG ATG GGT TTA CAA TAA AAC TCA AGC AAT TTT GAC TTT TTC CTT CTA AAA GAT CTT CAA AAA ATT CCT CCA TAT CAC CAA CTC TTT ACA AAC GAA AGA TTT TAA TTC CTT CTT GAT TGC GAA AGA GAG TTA AAT AAA GAC ATT TTA AAT AAT GAA TAA CTT ATT TAA GAC TTT GTT TAG AGA GCT TAA AAT TCC TAG ACT TCT GAT TAA GAA TTG GTT TTA ATA TCA AAA AAA GGA AAA GTT GGT GAA GAA ATT ATT CAC AAT AAT TCT GTT TAT ACA TAG ATA TTC TTA TGT GAG TTG AGT TCA GCC TTT GTT TTT GGC TAC TTT GTT GTC AAA GAT ATG AGT TCT TTT GCA AAT TAA ATT TGT ATA AAT TTA GAG AGT TTT ACT AAT CAA AAC CAT CAT GTA TAT TTT TAG AAC GAA GAA TTT TTT TCT AAT TAT GAA AAA ATT TAA GAA CTT TTG AAT AGC AAA ATA CAC ATA AGT TCT TTT TTA AAT AAC AAA TTT GAC TAA TTT CCA TAA TCT CTT TAA AAT GAA ATG CTC CAC AAT AAA CCA TTA AAA GCA AAT AAC AGT GAG ACT ATA TTT GAT AGG CAG ACT TAA ACT TAG CTT CTT ATT AAA TCG GAT GAA AAT TTA AAG AAA GAA GTC TTT TTA ACT ACC AGT GGT ACA GTT AAA TAA GAT AAA ATG GTT GAA AAG CAT AAG CAA GCA ATT TAA AAA ATA ACT TAA AAG CTT AGA ATG CTA CTA ACA GAA TAC AGG TTT GTA AGT ATC AAT AAT GAT ACG ACA TCT ATC TTT GAA GAG TTA TCC GAG ATA GCG ATT TAA AAC TCT TAT ATA ATT TAT TCC CAA GCA AAA GAA AAA ATG GAT TAC AGA CTA TTT AGA TTT AAA TTA GCA TAA GAT TTA CTC TAA AAA TAA ATA CAA AAG ATA AAA TAA GAG GAA TTA TAA AAT GTT AAA TCT AAA CTA ATT GAT GTT GAA GTT TAA ACA GAT AAA GTT GTT GAA AGT GTA ATA AAT GTT GAA ACT CAC GCT CTT TCT AAA TCT CCA AAA TCA TCA GAT AAT AAT GAA TAG TTC ATA ATG AAT GAA GTT AAT TCA CCT GTC TTT TAG GGA AAT GAT TAA AAT ATC AGA CAA GGA GGT ACT CAT GTC TAG AAA AAA GAT GGT AAG TAA GGT ATT TGC TTA GTT TGC TTA CAA GAA AAA AAT ATT TAA AAT AAT ACA TTC ATA ACA TGC TAA GAA TGC TCT TTA CAA AAT AAA AAG CCA GTT TAT TTA TGT GAC AAG TGC TTT GAA GTA TAT CAT TTA GAG ATA AAT GTT AAC AGA GAC AAC TTT GAT AAA AAA AAT TTC TCT AGG CTA AGC ACC CTA AAA AAT TCA GTT ACA ACA GTT CCA ATA GAT AAA ATG GCA CCT AAG CCA TTA TAA AAT GGA TAT GGA AGT AAT GGA CTC AAT GGA GGT TAC AAT ACG GTT AAT CCT CCT ATT TAG TAA CCT TTA ATG AAC AAT GGG TAC AAT GGA TAT TAA CCA TAA TAA ACT TAA GTG AGG AGA AGA AGA ACA GCT AAT ATT TAA GAT GGG TAT GAA ACT TCA GGC CCT GCC TTT AAC TCA ATG GTA CCA CCT CAA ATG AAT GGA AAT ATG ATG GGA TAA TAA ATT CCT TTA AAA AGA AGA GGA CCT GCT TTG GAT GAC TCT GGA TTT AGA AGT GAT GCC CCT TCA AGC TAT ATT CCT GCT ACA AGA GGC AGA AAG AAA TTA AAT CAT GGC TAA GAC TAA TTA CCA CCT AGA AAT CAA TAT GGT TAC TCT GAT TTA GGA TAG CCA AAC AAC ATG AAT GGA TAT GGA TAA GGG ATG GGA AAT AAT GCA ACA AAT GGA TAT GAT AGA TAC TCA AGA GGA GTT GAC ATG AAT GGA TAT ACT ACT TCA GAT CCT GCA TAT GGC AGA AAT TAT CAA GGG GCA GAT AAT TAC AAT AAT AAT TAA ATA TAT AGA GGT GTA GGT ACT CAA AGA AAG TGA >TTHERM_00653910(protein)M E L G E A D L H T S Q S I V Q E E V P M Q Q E V N I Q E E Q N S Q F D N V Q Q Q N Q N V E E Q H Q T N K N N L T Q N D F N E F Q Q Q N T N E Q D L P R N D Q T Q V Q P Q Q N L Q D E N N Q D Q T I H F T E Q H F Q Q R E R E S S E T H D T S N Q E L E Y Q I N Q N I N E N K Q V Q K D N L N E E I I S Q N K E A L D G Q E D Y Q N F N K K D L P D N N N S N E Q H N Q D Q E N M N Q I E S Q E G Q N Q L V Q I E V N G S V N S L Q E N N Y I Q D G T F M E Q E H L N D K M Q Q Q Q E Q A V K E E T E E R E E M Q E E N Q L H E N Q E N I S I S Q Q N Q Q A H S D M Q I E V Q A N Q I N Q Q E N Q L E S L N D K E V V K E E N N L L L N I L S D E N N K R F Q R L P P E L S P N I F C H F L G G K S L Q L T N I N D S S R L F M Y F L G T K I L R Q L L N K A N V K L R E I Y K K Q N D V K E Y T I E E I Q V Y Q A L K I L M G L Q Q N S S N F D F F L L K D L Q K I P P Y H Q L F T N E R F Q F L L D C E R E L N K D I L N N E Q L I Q D F V Q R A Q N S Q T S D Q E L V L I S K K G K V G E E I I H N N S V Y T Q I F L C E L S S A F V F G Y F V V K D M S S F A N Q I C I N L E S F T N Q N H H V Y F Q N E E F F S N Y E K I Q E L L N S K I H I S S F L N N K F D Q F P Q S L Q N E M L H N K P L K A N N S E T I F D R Q T Q T Q L L I K S D E N L K K E V F L T T S G T V K Q D K M V E K H K Q A I Q K I T Q K L R M L L T E Y R F V S I N N D T T S I F E E L S E I A I Q N S Y I I Y S Q A K E K M D Y R L F R F K L A Q D L L Q K Q I Q K I K Q E E L Q N V K S K L I D V E V Q T D K V V E S V I N V E T H A L S K S P K S S D N N E Q F I M N E V N S P V F Q G N D Q N I R Q G G T H V Q K K D G K Q G I C L V C L Q E K N I Q N N T F I T C Q E C S L Q N K K P V Y L C D K C F E V Y H L E I N V N R D N F D K K N F S R L S T L K N S V T T V P I D K M A P K P L Q N G Y G S N G L N G G Y N T V N P P I Q Q P L M N N G Y N G Y Q P Q Q T Q V R R R R T A N I Q D G Y E T S G P A F N S M V P P Q M N G N M M G Q Q I P L K R R G P A L D D S G F R S D A P S S Y I P A T R G R K K L N H G Q D Q L P P R N Q Y G Y S D L G Q P N N M N G Y G Q G M G N N A T N G Y D R Y S R G V D M N G Y T T S D P A Y G R N Y Q G A D N Y N N N Q I Y R G V G T Q R K >TTHERM_00653910(gene)ATG GAA TTA GGA GAA GCA GAT TTA CAT ACA TCA CAA TCA ATA GTT TAG GAA GAA GTT CCT ATG CAA CAA GAG GTT AAT ATT CAA GAA GAA TAA AAT TCT TAA TTT GAC AAT GTT TAA TAA CAA AAT CAG AAT GTA GAA GAA TAA CAT TAA ACA AAT AAA AAT AAT TTA ACT TAA AAT GAT TTT AAT GAA TTT CAA TAA TAA AAT ACA AAT GAG CAA GAC TTA CCA AGA AAC GAT CAA ACA TAG GTT TAA CCT CAA TAA AAC TTG TAG GAT GAA AAT AAT TAA GAC TAA ACT ATA CAT TTT ACA GAG TAG CAC TTT CAA CAA CGA GAA AGG GAA TCT AGT GAA ACT CAT GAT ACA AGC AAT TAA GAA TTA GAA TAT TAA ATT AAT TAA AAT ATA AAT GAA AAT AAA TAA GTA CAA AAA GAT AAC TTA AAT GAA GAA ATT ATA TCT TAA AAT AAA GAA GCA CTT GAT GGA CAA GAA GAT TAT CAG AAT TTC AAT AAA AAA GAT TTA CCT GAT AAT AAT AAT AGT AAT GAA TAA CAT AAC TAA GAT TAA GAA AAT ATG AAT TAA ATT GAA AGT TAA GAA GGT TAA AAT TAA TTA GTT TAG ATA GAA GTC AAT GGT TCA GTG AAT AGC CTA TAA GAA AAT AAC TAC ATC TAA GAT GGC ACG TTT ATG GAG TAA GAA CAT TTA AAT GAT AAA ATG CAA TAA TAA TAG GAA TAG GCT GTA AAA GAA GAA ACT GAA GAA AGA GAA GAA ATG TAA GAG GAG AAT TAA CTC CAT GAA AAT TAA GTA TTC TTT AAT TTT ACT TAT ATT ATT TTT AAC TTA AAC TTA AAT TTT TAA GGA AAA TAT TAG TAT CAG CTA ATA AAA TTA GTA AGC TCA CAG TGA TAT GTA AAT CGA AGT GTA AGC AAA TTA AAT TAA TTA ATA AGA GAA CCA GTT AGA ATC TTT AAA TGA CAA GGA AGT TGT TAA AGA AGA AAA TAA TTT GCT TTT AAA TAT ACT TTC TGA TGA AAA TAA TAA AAG ATT TCA AAG ACT TCC ACC AGA ATT GTC TCC CAA TAT TTT TTG TCA TTT TTT GGG AGG CAA ATC ATT ACA ATT GAC TAA CAT CAA TGA TTC TAG CAG GCT TTT TAT GTA TTT CTT GGG AAC TAA GAT ATT AAG ATA GCT GCT TAA TAA AGC AAA TGT AAA GCT AAG AGA AAT TTA CAA GAA ATA AAA TGA CGT TAA GGA ATA TAC TAT TGA AGA AAT ACA AGT CTA TTA AGC TTT GAA AAT TTT GAT GGG TTT ACA ATA AAA CTC AAG CAA TTT TGA CTT TTT CCT TCT AAA AGA TCT TCA AAA AAT TCC TCC ATA TCA CCA ACT CTT TAC AAA CGA AAG GTG GCT AAT TTA CAA TTT TAC AAT TTT ATA TTT AAA ATA TTT TAA TGT TTT AAA AAT AGA TTT TAA TTC CTT CTT GAT TGC GAA AGA GAG TTA AAT AAA GAC ATT TTA AAT AAT GAA TAA CTT ATT TAA GAC TTT GTT TAG AGA GCT TAA AAT TCC TAG ACT TCT GAT TAA GAA TTG GTT TTA ATA TCA AAA AAA GGA AAA GTT GGT GAA GAA ATT ATT CAC AAT AAT TCT GTT TAT ACA TAG ATA TTC TTA TGT GAG TTG AGT TCA GCC TTT GTT TTT GGC TAC TTT GTT GTC AAA GAT ATG AGT TCT TTT GCA AAT TAA ATT TGT ATA AAT TTA GAG AGT TTT ACT AAT CAA AAC CAT CAT GTA TAT TTT TAG AAC GAA GAA TTT TTT TCT AAT TAT GAA AAA ATT TAA GAA CTT TTG AAT AGC AAA ATA CAC ATA AGT TCT TTT TTA AAT AAC AAA TTT GAC TAA TTT CCA TAA TCT CTT TAA AAT GAA ATG CTC CAC AAT AAA CCA TTA AAA GCA AAT AAC AGT GAG ACT ATA TTT GAT AGG CAG ACT TAA ACT TAG CTT CTT ATT AAA TCG GAT GAA AAT TTA AAG AAA GAA GTC TTT TTA ACT ACC AGT GGT ACA GTT AAA TAA GAT AAA ATG GTT GAA AAG CAT AAG CAA GCA ATT TAA AAA ATA ACT TAA AAG CTT AGA ATG CTA CTA ACA GAA TAC AGG TTT GTA AGT ATC AAT AAT GAT ACG ACA TCT ATC TTT GAA GAG TTA TCC GAG ATA GCG ATT TAA AAC TCT TAT ATA ATT TAT TCC CAA GCA AAA GGT AAA TAA AAT GAT AAA AAA TTT AAT AAC CAT AAT CTT TTT TAT TTA AAA AAT TTT TTT AAA ATA TTT AAA TAG AAA AAA TGG ATT ACA GAC TAT TTA GAT TTA AAT TAG CAT AAG ATT TAC TCT AAA AAT AAA TAC AAA AGA TAA AAT AAG AGG AAT TAT AAA ATG TTA AAT CTA AAC TAA TTG ATG TTG AAG TTT AAA CAG ATA AAG TTG TTG AAA GTG TAA TAA ATG TTG AAA CTC ACG CTC TTT CTA AAT CTC CAA AAT CAT CAG ATA ATA ATG AAT AGT TCA TAA TGA ATG AAG TTA ATT CAC CTG TCT TTT AGG GAA ATG ATT AAG TAA AAT TTT AAG AAA ATA AAC GAA CAT CTT ATT AAA TAA TTA TAA TTT TTA GAA TAT CAG ACA AGG AGG TAC TCA TGT CTA GAA AAA AGA TGG TAA GTA AGG TAT TTG CTT AGT TTG CTT ACA AGA AAA AAA TAT TTA AAA TAA TAC ATT CAT AAC ATG CTA AGA ATG CTC TTT ACA AAA TAA AAA GCC AGT TTA TTT ATG TGA CAA GTG CTT TGA AGT ATA TCA TTT AGA GAT GTA TGA TAA ATA TCA AAT TTA TTT TAA TAG ATT TTT ATT TAT TTT ATT TTT TGA AAT AGA AAT GTT AAC AGA GAC AAC TTT GAT AAA AAA AAT TTC TCT AGG CTA AGC ACC CTA AAA AAT TCA GTT ACA ACA GTT GTA ATA CAA ACT TAA TCA TCC TTT CAA AAT GAA TAT TTA TGT ATA TTT TTA ATC TAA AAA GCC AAT AGA TAA AAT GGC ACC TAA GCC ATT ATA AAA TGG ATA TGG AAG TAA TGG ACT CAA TGG AGG TTA CAA TAC GGT TAA TCC TCC TAT TTA GTA ACC TTT AAT GAA CAA TGG GTA CAA TGG ATA TTA ACC ATA ATA AAC TTA AGT GAG GAG AAG AAG AAC AGC TAA TAT TTA AGA TGG GTA TGA AAC TTC AGG CCC TGC CTT TAA CTC AAT GGT ACC ACC TCA AAT GAA TGG AAA TAT GAT GGG ATA ATA AAT TCC TTT AAA AAG AAG AGG ACC TGC TTT GGA TGA CTC TGG ATT TAG AAG TGA TGC CCC TTC GTA ATT TTT CTT AGA TAT TTA TAA ATT TAT CAA ATA ATT ATT TTT TAT AAA CAG AAG CTA TAT TCC TGC TAC AAG AGG CAG AAA GAA ATT AAA TCA TGG CTA AGA CTA ATT ACC ACC TAG AAA TCA ATA TGG TTA CTC TGA TTT AGG ATA GCC AAA CAA CAT GAA TGG ATA TGG ATA AGG GAT GGG AAA TAA TGC AAC AAA TGG ATA TGA TAG ATA CTC AAG AGG AGT TGA CAT GAA TGG ATA TAC TAC TTC AGA TCC TGC ATA TGG CAG AAA TTA TCA AGG GGC AGA TAA TTA CAA TAA TAA TTA AAT ATA TAG AGG TGT AGG TAC TCA AAG AAA GTG A
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Homologs (v.2006 protein sequences)
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