Identifiers and Description

Gene Model Identifier

TTHERM_00322760

Standard Name

KAT1 (KATanin 1 )

Aliases

PreTt15995 | 32.m00239

Description

Katanin p60 catalytic subunit

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• ciliary basal body (IDA) | GO:0036064 | Ref:27726198

Domains

• ( PF00004 ) ATPase, AAA family
• ( PF00515 ) tetratricopeptide repeat
• ( TIGR01242 ) 26S proteasome subunit P45 family
• ( TIGR01241 ) ATP-dependent metallopeptidase HflB
• ( PF09336 ) Vps4 C terminal oligomerisation domain
• ( TIGR00179 ) UDP-N-acetylenolpyruvoylglucosamine reductase
• ( PF07724 ) ATPase family associated with various
• ( PF07728 ) ATPase family associated with various

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.9%

TetraMine Data

TTHERM_00322760

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_10067.1	9.997093137033517e-262	ATPase, AAA family protein (64 8 aa)
Oxytricha	Contig7897.0.0.g35	2.0004037638327014e-151	ATPase family associated with various cellular activities (A AA)
WormBase	WBGene00003183	1.9993206333383003e-80	locus:mei-1 Meiotic spindle formation protein mei-1 stat us:Confirmed UniProt:P34808 protein_id:CAB00052.1
SGD	YPR173C	1.0004671766404936e-76	VPS4 AAA-ATPase involved in mu ltivesicular body (MVB) protei n sorting, ATP-bound Vps4p loc alizes to endosomes and cataly zes ESCRT-III disassembly and membrane release; ATPase activ ity is activated by Vta1p; reg ulates cellular sterol metabol ism
DictyBase	DDB_G0268334	4.000989088096131e-71	DDB_G0268334 on chromosome: 1 position 714031 to 716367
Stentor Coeruleus	SteCoe_28576	1.7785284761271306e-68

General Information

No Data fetched for General Information

Associated Literature

1. Ref:27726198: Waclawek E, Joachimiak E, Hall MH, Fabczak H, Wloga D (2017) Regulation of katanin activity in the ciliate Tetrahymena thermophila. Molecular microbiology 103(1):134-150
2. Ref:17821280: Harrison JA, Fowler EH (1945) AN ANTIGEN-ANTIBODY REACTION WITH TETRAHYMENA WHICH RESULTS IN DYSTOMY. Science (New York, N.Y.) 102(2638):65-6

Sequences

>TTHERM_00322760(coding)
ATGTCAAATTCAGATAAACAATTAGAAGATCTTAAAAATTACATCAGTTTAGCGAGAGAA
AGCGCATATTTCGGCAAGTATTCTGAAGCAATTAACACTTTTAAAAAGGGCTTAGAAGTT
GCTGGCATGTTCAAGGTAAAGGCTGTAGAATAATATGCTTAGTAGGTATGGGAAAAATTT
GTGCTAGACTTATAAGCAGAATTCGATATAATCTCTTAATTGCAAGCAGTTAACCACGGA
TTTAAACCTCAACCACCTAATGGAGCAAACAAATAAGCTAATAATTAGAATGGTTAATAA
GGATAATAATAAAATTAACTCGATCATGATAAAAAATATCCTTTTGGTATTAAACCTTTT
TCTCACTTCGAAGATAACAAAATGAACAATAACAATAATAACAATAATAATAATAATAAT
AATAATAATCCTTTTAGATAGCAAGATAAGAATTTCTTACACAATTAACAATACTAAAAC
AATTTACCTGATCAAAATATGCACAATAACTAAAACTACAATAACTTTTAAGCACCTCAT
CAATACAATATGAATAGATAAGGTGGACCTGGAATGTAAGGAAATTATGGTTAAAACAAT
TATCAAAGTAATAACCCTAGCAACTATGGATATAATGACTTTTAGGATAATCCCTCATAA
AATTTTAATAGCCCTAATATTGAATACAATTAAAGATAAAATAGAAACCCTGCCAATAAT
GATTAAGGTAATTAAGATCCTGACGTTTGGCCAGCTCCTCCTCCTAAAGTCAACAAAGCC
AATAAAGCCCCTTAGAAGAATAAAACCCCTATTTACAATTTAAAAGAACTTCAGTAAAAG
CAAAATGATAATAATAATAACAATAATGCTAAAAAAGATGATAAAGAAAAGGCTAAAAGA
GATTACAATAAACCATGGTAAAGAAATGCTTAGACTCCTCAAGCAAAGAAAAAAGGTGAT
GAAGGAGAGAAAAAATAAAGCTTCTTAAATTTTTGTTATCCAAACGGATAAGGTCCTGAT
TCCGATTTGATAGCAATGCTTGAAAGAGATGTAGTAGATTAAAATCCTAATATCAGCTTT
GACTAAATCGCAGAGCTTGATAAAGCTAAAGATATGCTTTAAGAGGCTGTTTTGCTTCCT
ATTCTGATCCCTTAATATTTTAGAGGTATTCGTAGACCTCTTAAAGGAGTTCTTATGTTT
GGTCCTCCTGGTACTGGTAAAACCATGTTAGCAAAAGCTGTAGCAACAACTGGTAAAACC
ACATTCTTTAATGTTTCTGCCAGTAGTTTGGCTTCAAAGTGGAGAGGTGATTCAGAGAAA
CTAGTCAGAATTCTTTTCGAGATGGCAAGGTACTATGCACCTAGTACTATATTTTTCGAT
GAGATAGATGCTATTGGTTCTAAAAGAGTAGATGGAGAGTGCGAAGCAAATAGAAAAATG
AAAGCTGAAATGCTCATTTAAATTGATGGTGTAAGCAGCTCTTCAACAGATGAAAAAGAT
AGAAAATAAGTTATGGTCTTGGCAGCCACTAATAGACCTTGGGATTTAGATGAAGCTTTA
AGAAGAAGACTCGAAAAAAGAATTTTAATTCCTTTACCTTCCACTGAAGGCAGAAAGCAA
TTATTTGAGTTGAATATGAGAGGTATTAAATGCTCGGATGACATAGACTGGGTTGAATTA
GTTGGTAAAACTGATGGTTATTCAGGTGCTGATATAGCAAGTCTTTGCAGAGAAGCAGCT
TTTATGCCTATGAGAAGAAAATTAATGAAAGAAGGTGGTTTTAAAAATATTGAAAACATA
GAAAATCTTGCCTAGGAAAGTGACATACCGTTAACATAAAAAGATTTCGAAGAAGCTTTA
AGAAATGTAAATAAATCAGTAAGCAACGATGATCTAGAAAATTTTGAAAAATGGATGGCA
GAATTTGGTTCTGTTTGA

>TTHERM_00322760(protein)
MSNSDKQLEDLKNYISLARESAYFGKYSEAINTFKKGLEVAGMFKVKAVEQYAQQVWEKF
VLDLQAEFDIISQLQAVNHGFKPQPPNGANKQANNQNGQQGQQQNQLDHDKKYPFGIKPF
SHFEDNKMNNNNNNNNNNNNNNNPFRQQDKNFLHNQQYQNNLPDQNMHNNQNYNNFQAPH
QYNMNRQGGPGMQGNYGQNNYQSNNPSNYGYNDFQDNPSQNFNSPNIEYNQRQNRNPANN
DQGNQDPDVWPAPPPKVNKANKAPQKNKTPIYNLKELQQKQNDNNNNNNAKKDDKEKAKR
DYNKPWQRNAQTPQAKKKGDEGEKKQSFLNFCYPNGQGPDSDLIAMLERDVVDQNPNISF
DQIAELDKAKDMLQEAVLLPILIPQYFRGIRRPLKGVLMFGPPGTGKTMLAKAVATTGKT
TFFNVSASSLASKWRGDSEKLVRILFEMARYYAPSTIFFDEIDAIGSKRVDGECEANRKM
KAEMLIQIDGVSSSSTDEKDRKQVMVLAATNRPWDLDEALRRRLEKRILIPLPSTEGRKQ
LFELNMRGIKCSDDIDWVELVGKTDGYSGADIASLCREAAFMPMRRKLMKEGGFKNIENI
ENLAQESDIPLTQKDFEEALRNVNKSVSNDDLENFEKWMAEFGSV

>TTHERM_00322760(gene)
ATGTCAAATTCAGATAAACAATTAGAAGATCTTAAAAATTACATCAGTTTAGCGAGGTAA
ATTTGTTTTTTAATCATTTGAATAAAATTATTATATGTAGAATACCCATCAGCATATTAA
CTAATTCTATTATTAATTATTAGAGAAAGCGCATATTTCGGCAAGTATTCTGAAGCAATT
AACACTTTTAAAAAGGGCTTAGAAGTTGCTGGCATGTAAATAGATTGCTTCAATATTGAA
ATTTAATATTACAAAACTTTCTTATGAAAATTAAGACTTGTTTGGTTAAAAAATATATCA
TTTTATCCAGAATAATTGATTTGCGATAAACAATATATATTTTTGTTTTTTTAAATAAAG
GTTCAAGGTAAAGGCTGTAGAATAATATGCTTAGTAGGTATGGGAAAAATTTGTGCTAGA
CTTATAAGCAGAATTCGATATAATCTCTTAATTGCAAGCAGTTAACCACGGATTTAAAGT
AAGCTTTATTCAATTTATGAGCATTAATAGAATCATTTTTTTGAATTAATTTATAAAGCC
TCAACCACCTAATGGAGCAAACAAATAAGCTAATAATTAGAATGGTTAATAAGGATAATA
ATAAAATTAACTCGATCATGATAAAAAATATCCTTTTGGTATTAAACCTTTTTCTCACTT
CGAAGATAACAAAATGAACAATAACAATAATAACAATAATAATAATAATAATAATAATAA
TCCTTTTAGATAGCAAGATAAGAATTTCTTACACAATTAACAATACTAAAACAATTTACC
TGATCAAAATATGCACAATAACTAAAACTACAATAACTTTTAAGCACCTCATCAATACAA
TATGAATAGATAAGGTGGACCTGGAATGTAAGGAAATTATGGTTAAAACAATTATCAAAG
TAATAACCCTAGCAACTATGGATATAATGACTTTTAGGATAATCCCTCATAAAATTTTAA
TAGCCCTAATATTGAATACAATTAAAGATAAAATAGAAACCCTGCCAATAATGATTAAGG
TAATTAAGATCCTGACGTTTGGCCAGCTCCTCCTCCTAAAGTCAACAAAGCCAATAAAGC
CCCTTAGAAGAATAAAACCCCTATTTACAATTTAAAAGAACTTCAGTAAAAGCAAAATGA
TAATAATAATAACAATAATGCTAAAAAAGATGATAAAGAAAAGGCTAAAAGAGATTACAA
TAAACCATGGTAAAGAAATGCTTAGACTCCTCAAGCAAAGAAAAAAGGTGATGAAGGAGA
GAAAAAATAAAGCTTCTTAAATTTTTGTTATCCAAACGGATAAGGTCCTGATTCCGATTT
GATAGCAATGCTTGAAAGAGATGTAGTAGATTAAAATCCTAATATCAGCTTTGACTAAAT
CGCAGAGCTTGATAAAGCTAAAGATATGCTTTAAGAGGCTGTTTTGCTTCCTATTCTGAT
CCCTTAATATTTTAGAGGTATTCGTAGACCTCTTAAAGGAGTTCTTATGTTTGGTCCTCC
TGGTACTGGTAAAACCATGTTAGCAAAAGCTGTAGCAACAGTAAGTTTTTTTAAAAATTA
TATAAAAATATTTTTTAAAAATAAATCTCAAAGAAAAAACATAAATTTTACATAAGAAAG
AAAGAATCATTTTAATATAAAAGTATAAATTTACTTTAAATATAAATAAAATGCCTAATT
TTTAAATTAAGTTTCTGGAATAAAAAAATAGAACTTTTATTTTTAATTTGTCTTTAAACA
AGCTCGCTCTAGAATTTTATTAATTTTGATTCTTGGCTCGTTCATTATCTAAAAATAAAT
TTACTAAATTTATTTTAGAAATTTTCTTTTATTTTACTTTTGAAAATATTTTTTGAACTA
AAAAAAAAATATTTTTGTTTTTACAAATTTTAATTTCAAAATTATTTTTTTTCATTTAAA
AAAAGACTGGTAAAACCACATTCTTTAATGTTTCTGCCAGTAGTTTGGCTTCAAAGTGGA
GAGGTGATTCAGAGAAACTAGTCAGAGTAAATTTCTCTATAACAAACTTTAATAAATAGG
ATTAATTTATTAATTCATTATTTAATTAGATTCTTTTCGAGATGGCAAGGTACTATGCAC
CTAGTACTATATTTTTCGATGAGATAGATGCTATTGGTTCTAAAAGAGTAGATGGAGAGT
GCGAAGCAAATAGAAAGTAAAAATTTAAATTTAAACTAATCTATATTTCTTAAACAAACA
ACTATGATAATAATTATATCTAAAATTAAGAATGAAAGCTGAAATGCTCATTTAAATTGA
TGGTGTAAGCAGCTCTTCAACAGATGAAAAAGATAGAAAATAAGTTATGGTCTTGGCAGC
CACTAATAGACCTTGGGATTTAGATGAAGCTTTAAGAAGAAGACTCGAAAAAAGAATTTG
TAATTCGAATAAAAAAGTGTAAATAAAAATAGTAATATATTTTTTAATCTATAAATAGTA
ATTCCTTTACCTTCCACTGAAGGCAGAAAGCAATTATTTGAGTTGAATATGAGAGGTATT
AAATGCTCGGATGACATAGACTGGGTTGAATTAGTTGGTAAAACTGATGGTTATTCAGGT
GCTGATATAGCAAGTGTAATTTATTTTTCATTTTTATTCTAAATTTAGCACAATTTCTTA
TGATTAAAATAGCTTTGCAGAGAAGCAGCTTTTATGCCTATGAGAAGAAAATTAATGAAA
GAAGGTGGTTTTAAAAATATTGAAAACATAGAAAATCTTGCCTGTAAGATTTTTATATTT
AAAAACTACATTAATATTGAAATTTTTTTTAAATAAAGAGGAAAGTGACATACCGTTAAC
ATAAAAAGATTTCGAAGAAGCTTTAAGAAATGTAAATAAATCAGTAAGCAACGATGATCT
AGAAAATTTTGAAAAATGGATGGCAGAATTTGGTTCTGTTTGA