Identifiers and Description

Gene Model Identifier

TTHERM_01415190

Standard Name

JUB6 (Junk buster 6)

Aliases

PreTt14740 | 376.m00013 | PRN1

Description

Prion-like protein Jub6p that is required for heterochromatin aggregation process during programmed DNA elimination

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• heterochromatin (IMP) | GO:0000792 | Ref:27909245

Biological Process

• heterochromatin assembly involved in chromatin silencing by small RNA (IMP) | GO:0070924 | Ref:27909245
• heterochromatin domain assembly (IMP) | GO:1902795 | Ref:27909245

Domains

• ( PF05316 ) Mitochondrial ribosomal protein (VAR1)

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 12%

TetraMine Data

TTHERM_01415190

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_03361.1	4.998233068678632e-48	hypothetical protein (568 aa)

General Information

Paragraph No	Gene Name	Paragraph Text
111	JUB1, JUB2, JUB3, JUB4, HPL2, COI3, COI6, COI16, JUB6	This protein co-localizes with Pdd1p in heterochromatin body in the new macronucleus.

Associated Literature

1. Ref:27909245: Kataoka K, Mochizuki K (2017) Heterochromatin aggregation during DNA elimination in Tetrahymena is facilitated by a prion-like protein. Journal of cell science 130(2):480-489

Sequences

>TTHERM_01415190(coding)
AAATTTTATAAAAAAAAATAAATAAATAAATTAGTTATATTCATGATGGATTAAATAAAT
AATAGCAATATCTAAAACTAATTATTGTGCTTGAAGCACTATTAGCAATCAGAATACTTG
CAATTTGCCAGTGATAATGAAGAAGATCTATTTTGCTGCTACAATTGTTTGTATGAAGAG
TGTTATAAAGTAAAGAATATGATACCTTTAGAAAAAATTTAAAGTTGTGAAGAAGATCAT
ATTATATTTTCGTGGCCTCCTCTTGACGAGTAAGATTTAGTTTGTTAGATATACCAAATT
AGCCAATATGATAACCCTATTAGCATATAAAAGTTAATTTAATTTTTTGATGAATTAGAA
ACAGAAATTATAACTCATTTATAGAAATAAAAAAAGGCCTTTTTAGTAAAAATTAATAAT
ATTTCCACTTAAAATTAAGAATTATTAGATTTCTATTCTAAAATTTCTAAATTAAGTGAC
ATAAAAGGTATAATTTAGGATTAAAATCTAACTCAATTGCAAAAAGCTAAACAAGTATTA
GCTATTATCAACAAAATGAAAGAAAAGTCAACTGAAAACACACATAAACTTAAGCAAATG
CTTTAAAAATCAATTTAGTAAAAAGCTGTTGATTTATAATTGCTAACGAAGCTTAAAAAT
TCTATCTTAAAGTAACTCAGCTTCATTAACTCTCAATCTATGCAATAGCTGCAGTAATTT
CTTGAAAAGAATTACTGTTTGATAGAGCAATAAAAAAGTGAAAACAATTTACAGAATGAA
AACATAAAACTTTAAGAAAATGGAAATCTTGACACAATTTTAAAATTAGTTGCAAACAAA
ACAAATCAATGCGACTCAAAATACTTGGATTCACTTCAATCTGAGCTTCTCAAAATTTAA
GTCATAATAAATGACTTGAAAATAGAAAAGAATGTTTTTCTACCAAGCAAGCAATAAATC
AACTTTTAAGATTTTACTTAAGAGTAAATCGATGACATTCATTTGCTTAGTAAAAAAATA
AGCGAGATGAACAACAAATACAGATGCAGCTAAGAATAAGAAATTTTATCATTCAAAATT
TAACCATCTTCTTATTCTACTTGTAGAGCTTTGTTTAATTAAAACATAATTAAGCAAAAT
AAATTAAATTATTATTATAATTTACTAAAAAAATACCCTATTTTCGAGTTTGAAAGCTTT
TATAAGTCTTACTTTAATTGTAGATATTAATTACAACTTAGCTCTCTAAACAACAGCTAG
CAGTATGGACAAATAATTCAAAACAATTCAAATTATATATTCTAAGTAGTCCAGCAATCT
AACACTACCACTGCTTATATGAAAATAAACTAGGCTAGCTTGTATAGAGTAGTAGTTGAA
ATGAACCTCCATAATGTCTATAATAAGTATTACATTTTCGTTGGTCTTATAAGCAACTTT
AGTAAAGATAATACATATATTTCTGATGTGAACAAAGTCAACAGTTTTGCAGTTGATAGG
TAAAGCACAAGCAAAGGAGTTAGTAAAATCGTGAAAGGAAGGGTTCTAAAAGACTTACAG
TATCCCGATGATTACAAGCAGATAGAAATTACCTTTTGTGTTGAATCAAAGCTCTTTTAA
GTATGCGATTACCCTAACAGAGAAAATGTTAATGAAATTGATGACAACAGATTGTATCTG
TTAAATACCAGTTAAGAATATCTTTTAGGCTTTTAACTCTTTAATAACGGCGACAGCATA
ACCATTTTACAATGTGAAGAATTAGAGTACCAAAACTGA

>TTHERM_01415190(protein)
KFYKKKQINKLVIFMMDQINNSNIQNQLLCLKHYQQSEYLQFASDNEEDLFCCYNCLYEE
CYKVKNMIPLEKIQSCEEDHIIFSWPPLDEQDLVCQIYQISQYDNPISIQKLIQFFDELE
TEIITHLQKQKKAFLVKINNISTQNQELLDFYSKISKLSDIKGIIQDQNLTQLQKAKQVL
AIINKMKEKSTENTHKLKQMLQKSIQQKAVDLQLLTKLKNSILKQLSFINSQSMQQLQQF
LEKNYCLIEQQKSENNLQNENIKLQENGNLDTILKLVANKTNQCDSKYLDSLQSELLKIQ
VIINDLKIEKNVFLPSKQQINFQDFTQEQIDDIHLLSKKISEMNNKYRCSQEQEILSFKI
QPSSYSTCRALFNQNIIKQNKLNYYYNLLKKYPIFEFESFYKSYFNCRYQLQLSSLNNSQ
QYGQIIQNNSNYIFQVVQQSNTTTAYMKINQASLYRVVVEMNLHNVYNKYYIFVGLISNF
SKDNTYISDVNKVNSFAVDRQSTSKGVSKIVKGRVLKDLQYPDDYKQIEITFCVESKLFQ
VCDYPNRENVNEIDDNRLYLLNTSQEYLLGFQLFNNGDSITILQCEELEYQN

>TTHERM_01415190(gene)
AAATTTTATAAAAAAAAATAAATAAATAAATTAGTTATATTCATGATGGATTAAATAAAT
AATAGCAATATCTAAAACTAATTATTGTGCTTGAAGCACTATTAGCAATCAGAATACTTG
CAATTTGCCAGTGATAATGAAGAAGATCTATTTTGCTGCTACAATTGTTTGTATGAAGAG
TGTTATAAAGTAAAGAATATGATACCTTTAGAAAAAATTTAAAGTTGTGAAGAAGATCAT
ATTATATTTTCGTGGCCTCCTCTTGACGAGTAAGATTTAGTTTGTTAGATATACCAAATT
AGCCAATATGATAACCCTATTAGCATATAAAAGTTAATTTAATTTTTTGATGAATTAGAA
ACAGAAATTATAACTCATTTATAGAAATAAAAAAAGGCCTTTTTAGTAAAAATTAATAAT
ATTTCCACTTAAAATTAAGAATTATTAGATTTCTATTCTAAAATTTCTAAATTAAGTGAC
ATAAAAGGTATAATTTAGGATTAAAATCTAACTCAATTGCAAAAAGCTAAACAAGTATTA
GCTATTATCAACAAAATGAAAGAAAAGTCAACTGAAAACACACATAAACTTAAGCAAATG
CTTTAAAAATCAATTTAGTAAAAAGCTGTTGATTTATAATTGCTAACGAAGCTTAAAAAT
TCTATCTTAAAGTAACTCAGCTTCATTAACTCTCAATCTATGCAATAGCTGCAGTAATTT
CTTGAAAAGAATTACTGTTTGATAGAGCAATAAAAAAGTGAAAACAATTTACAGAATGAA
AACATAAAACTTTAAGAAAATGGAAATCTTGACACAATTTTAAAATTAGTTGCAAACAAA
ACAAATCAATGCGACTCAAAATACTTGGATTCACTTCAATCTGAGCTTCTCAAAATTTAA
GTCATAATAAATGACTTGAAAATAGAAAAGAATGTTTTTCTACCAAGCAAGCAATAAATC
AACTTTTAAGATTTTACTTAAGAGTAAATCGATGACATTCATTTGCTTAGTAAAAAAATA
AGCGAGATGAACAACAAATACAGATGCAGCTAAGAATAAGAAATTTTATCATTCAAAATT
TAACCATCTTCTTATTCTACTTGTAGAGCTTTGTTTAATTAAAACATAATTAAGCAAAAT
AAATTAAATTATTATTATAATTTACTAAAAAAATACCCTATTTTCGAGTTTGAAAGCTTT
TATAAGTCTTACTTTAATTGTAGATATTAATTACAACTTAGCTCTCTAAACAACAGCTAG
CAGTATGGACAAATAATTCAAAACAATTCAAATTATATATTCTAAGTAGTCCAGCAATCT
AACACTACCACTGCTTATATGAAAATAAACTAGGCTAGCTTGTATAGAGTAGTAGTTGAA
ATGAACCTCCATAATGTCTATAATAAGTATTACATTTTCGTTGGTCTTATAAGCAACTTT
AGTAAAGATAATACATATATTTCTGATGTGAACAAAGTCAACAGTTTTGCAGTTGATAGG
TAAAGCACAAGCAAAGGAGTTAGTAAAATCGTGAAAGGAAGGGTTCTAAAAGACTTACAG
TATCCCGATGATTACAAGCAGATAGAAATTACCTTTTGTGTTGAATCAAAGCTCTTTTAA
GTATGCGATTACCCTAACAGAGAAAATGTTAATGAAATTGATGACAACAGATTGTATCTG
TTAAATACCAGTTAAGAATATCTTTTAGGCTTTTAACTCTTTAATAACGGCGACAGCATA
ACCATTTTACAATGTGAAGAATTAGAGTACCAAAACTGA