Identifiers and Description

Gene Model Identifier

TTHERM_00161640

Standard Name

IMA8 (Importin Alpha 8)

Aliases

PreTt28554 | 13.m00513 | 3829.m01375

Description

IMA8 importin subunit alpha putative; Armadillo/beta-catenin-like repeat family protein; Karyopherin/Importin alpha family member

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• micronucleus (EXP) | GO:0031040 | Ref:18676955

Domains

• ( PF00514 ) Armadillo/beta-catenin-like repeat

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.4%

TetraMine Data

TTHERM_00161640

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_05412.1	9.997093137033517e-262	hypothetical protein (616 aa)
DictyBase	DDB_G0272318	0.0000000000002999981760818895	DDB_G0272318 on chromosome: 2 position 1278811 to 1280712
WormBase	WBGene00002073	0.00000000000040012475857291343	locus:ima-2 Importin subunit alpha-2 status:Confirmed UniProt:P91276 protein_id:CC D64196.1
SGD	YNL189W	0.00000000006996681903814525	SRP1 Karyopherin alpha homolog , forms a dimer with karyopher in beta Kap95p to mediate impo rt of nuclear proteins, binds the nuclear localization signa l of the substrate during impo rt; may also play a role in re gulation of protein degradatio n
Oxytricha	Contig20249.0.g40	0.000000030002053728821195	Armadillo/beta-catenin-like re peat

General Information

No Data fetched for General Information

Associated Literature

1. Ref:18676955: Malone CD, Falkowska KA, Li AY, Galanti SE, Kanuru RC, LaMont EG, Mazzarella KC, Micev AJ, Osman MM, Piotrowski NK, Suszko JW, Timm AC, Xu MM, Liu L, Chalker DL (2008) Nucleus-specific importin alpha proteins and nucleoporins regulate protein import and nuclear division in the binucleate Tetrahymena thermophila. Eukaryotic cell 7(9):1487-99

Sequences

>TTHERM_00161640(coding)
ATGATTTAAGAATAATATAATTAGAATTTATAGATTATTGGCAGTCAAAATGTTAATTAG
GATTATAATTATGTAGATTATTAGCAATAAATTAATGGCCAAAACCCTTAAATGTCATAA
GAAAATCAGCAAAATTAAGAGGAAGAGGATGCGGGATTTAAGTAGCTGATGTCTAAGAAA
AAAGAATAGCACAGAGTAGAGATAAGAAGGAAGCAAAATTAGGAAAAATTTAAAATGAAT
AGAATATAAGTGAGTTATATTTAAGATTAGTAAAAACTCAAGGATTTTAGTGAAAAAGAC
AAATTAGATGTTGATTCATTAAATATAAATTAATGCATAGATGGATTTATTTAAGCTTAT
CATACAAACAACTTTGAGTTGATTAAATTTTAAGTTTTATGCATACGTCACTGTGTTACA
CTTGAACACAAGATAAAAGATTTAGAATTCTCTAATAAAGTTATTTTTGAAAAAGGATTG
ATGCAATTTTTAATTACCTATTTATCTCCTTAATATGACGATGATTATGAACTGCAAAGA
GATGCTATATGGATTATCGCTCACTTTTTGAGTGAATAAAATTTAAGACACATTCTTTAT
ATTTTGGAAAATGTCCCTCTGTAAACATTCTTTAGGCTCTTGGAATAAGGTCAAAAAACT
ATCAAAGAATATGCATTGCTTTCAATTAATAACATAATGGATGAGAATCCTATAGGTGTT
AAATTGCTTGTTGAAAATGGAATTATTTAAATTGTTAGAAATCTCGTATTAAATTTCCTA
CCAAATAATTAAAATCTAGTTTAGAGCACAATCAGAATAATAAATACTTTGATAAGCTAT
TCATAACAGAGTGATGGCTCATAGATTCCTATAGAAAATTTGATGCCAATAATTGAAGTG
ATTCTCCCTCTTTTTTAGTATGTGAAATAAGATGAAGAACTTACAGATGACTTATTTGAA
ACTATATAAAAAATTACATAAAGAGATGATGACGATATTGACCATTTCTATTAAACTTGC
AATGGAATTATATTAAAAACTTTACATTATATTAAAGACAACTAAAAATCAGCAAGATAA
TATTTGATTACTCCTTTAAGAATAATCTAAAATCTTACTAATAGCTATGATGATATTACA
GAAAATTTAATACAATTTGGATTGTTGGATATGATTAGCATGTTTGTAAAGCATAGATCT
ACTTAAATAAGAAATCTTATTCTGCATACTCTATCGAATGTATGTGCATCAGGAGCATTT
GTTATAGATTACATAATGTAGCATAAAATAATTATTATGGATATGATAAATATCATGGAA
AGTGGAGAATTCATTTTAAAAAAAGAAGCAACTATTGCATTTTGCAATATTTTTATGGTT
ATCAAAATGAAATAAATAGAAGAGTTTCTAACTGATTATAACGGAATATAGCTGCTTGTA
GATTAAATTAAGTATGTAGATGTTGATTTAAATATCAGTATTGTTAAAGCTCTTTACAGG
ATTATAAAGATTGGAGAAAAAATAAAAAATAAGAAAAACTACTTTTATAATATTTATGCA
AAAAAATTTAATTAGTACGGAGGTCGAGAAAGGGTTTAGGGGCTTGCTGAAAGTTAAAAT
AAGGATTTAAAAAGAATTTCAGAAAAGCTTCTTGCCCAGTCTTATATTGTAGATGAAGTA
GAAGAAGAAATGGAATAACAATACTAAGAAGAAAATGAAAAGATAAATAATGAGAGTTAA
GAAGAAAACGAAAGCGATTAAGATGACAATGATGATGATGGTTAGAACTAAGATTTAAAC
AATGGAAATAAACATTTATGA

>TTHERM_00161640(protein)
MIQEQYNQNLQIIGSQNVNQDYNYVDYQQQINGQNPQMSQENQQNQEEEDAGFKQLMSKK
KEQHRVEIRRKQNQEKFKMNRIQVSYIQDQQKLKDFSEKDKLDVDSLNINQCIDGFIQAY
HTNNFELIKFQVLCIRHCVTLEHKIKDLEFSNKVIFEKGLMQFLITYLSPQYDDDYELQR
DAIWIIAHFLSEQNLRHILYILENVPLQTFFRLLEQGQKTIKEYALLSINNIMDENPIGV
KLLVENGIIQIVRNLVLNFLPNNQNLVQSTIRIINTLISYSQQSDGSQIPIENLMPIIEV
ILPLFQYVKQDEELTDDLFETIQKITQRDDDDIDHFYQTCNGIILKTLHYIKDNQKSARQ
YLITPLRIIQNLTNSYDDITENLIQFGLLDMISMFVKHRSTQIRNLILHTLSNVCASGAF
VIDYIMQHKIIIMDMINIMESGEFILKKEATIAFCNIFMVIKMKQIEEFLTDYNGIQLLV
DQIKYVDVDLNISIVKALYRIIKIGEKIKNKKNYFYNIYAKKFNQYGGRERVQGLAESQN
KDLKRISEKLLAQSYIVDEVEEEMEQQYQEENEKINNESQEENESDQDDNDDDGQNQDLN
NGNKHL

>TTHERM_00161640(gene)
ATGATTTAAGAATAATATAATTAGAATTTATAGATTATTGGCAGTCAAAATGTTAATTAG
GATTATAATTATGTAGATTATTAGCAATAAATTAATGGCCAAAACCCTTAAATGTCATAA
GAAAATCAGCAAAATTAAGAGGAAGAGGATGCGGGATTTAAGTAGCTGATGTCTAAGAAA
AAAGAATAGCACAGAGTAGAGATAAGAAGGAAGCAAAATTAGGAAAAATTTAAAATGAAT
AGAATATAAGTGAGTTATATTTAAGATTAGTAAAAACTCAAGGATTTTAGTGAAAAAGAC
AAATTAGATGTTGATTCATTAAATATAAATTAATGCATAGATGGATTTATTTAAGCTTAT
CATACAAACAACTTTGAGTTGATTAAATTTTAAGTTTTATGCATACGTCACTGTGTTACA
CTTGAACACAAGATAAAAGATTTAGAATTCTCTAATAAAGTTATTTTTGAAAAAGGATTG
ATGCAATTTTTAATTACCTATTTATCTCCTTAATATGACGATGATTATGAACTGCAAAGA
GATGCTATATGGATTATCGCTCACTTTTTGAGTGAATAAAATTTAAGACACATTCTTTAT
ATTTTGGAAAATGTCCCTCTGTAAACATTCTTTAGGCTCTTGGAATAAGGTCAAAAAACT
ATCAAAGAATATGCATTGCTTTCAATTAATAACATAATGGATGAGAATCCTATAGGTGTT
AAATTGCTTGTTGAAAATGGAATTATTTAAATTGTTAGAAATCTCGTATTAAATTTCCTA
CCAAATAATTAAAATCTAGTTTAGAGCACAATCAGAATAATAAATACTTTGATAAGCTAT
TCATAACAGAGTGATGGCTCATAGATTCCTATAGAAAATGTATTTTATTATTATTTTTTG
TAAATTAAAATATTTTTAATAATTACAAAAAATTTAGTTGATGCCAATAATTGAAGTGAT
TCTCCCTCTTTTTTAGTATGTGAAATAAGATGAAGAACTTACAGATGACTTATTTGAAAC
TATATAAAAAATTACATAAAGAGATGATGACGATATTGACCATTTCTATTAAACTTGCAA
TGGAATTATATTAAAAACTTTACATTATATTAAAGACAACTAAAAATCAGCAAGATAATA
TTTGATTACTCCTTTAAGAATAATCTAAAATCTTACTAATAGCTATGATGATATTACAGA
AGTAACTATTTTTATAAATTCTTCTAAAATCAATAATAAAAAAATTATTAGAAAATTTAA
ATTCTTCTTAACTAAAATCCATGTTTTTTAAAAATTCTTATTAAAAATTAATATTTATTT
GATCTAAAAAAAATTTAGAGTTAAAATGAAGAATTTAAATAAAATCAATTTCATTAAATT
TAATTAAAGCTTATCGAATAATTTTAATTATTAATATATAAAGAATTTAATACAATTTGG
ATTGTTGGATATGATTAGCATGTTTGTAAAGCATAGATCTACTTAAATAAGAAATCTTAT
TCTGCATACTCTATCGAATGTATGTGCATCAGGAGCATTTGTTATAGATTACATAATGTA
GCATAAAATAATTATTATGGATATGATAAATATCATGGAAAGTGGAGAATTCATTGTAAT
AATTCAGCAATTTTAATTTGAAAACTTGTTTATTTTAATTTTTTTTATAATGAAAGTTAA
AAAAAGAAGCAACTATTGCATTTTGCAATATTTTTATGGTTATCAAAATGAAATAAATAG
AAGAGTTTCTAACTGATTATAACGGAATATAGCTGCTTGTAGATTAAATTAAGTATGTAG
ATGTTGATTTAAATATCAGTATTGTTAAAGCTCTTTACAGGATTATAAAGATTGGAGAAA
AAATAAAAAATAAGAAAAACTACTTTTATAATATTTATGCAAAAAAATTTAATTAGTACG
GAGGTCGAGAAAGGGTTTAGGGGCTTGCTGAAAGTTAAAATAAGGATTTAAAAAGAATTT
CAGAAAAGCTTCTTGCCCAGTCTTATATTGTAGATGAAGTAGAAGAAGAAATGGAATAAC
AATACTAAGAAGAAAATGAAAAGATAAATAATGAGAGTTAAGAAGAAAACGAAAGCGATT
AAGATGACAATGATGATGATGGTTAGAACTAAGATTTAAACAATGGAAATAAACATTTAT
GA