Identifiers and Description

Gene Model Identifier

TTHERM_00592800

Standard Name

IMA6 (IMportin Alpha 6)

Aliases

PreTt25033 | 82.m00123 | 3835.m00533

Description

Armadillo/beta-catenin-like repeat family protein; Karyopherin/Importin alpha family member

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• macronucleus (EXP) | GO:0031039 | Ref:18676955

Biological Process

• regulation of protein import into nucleus (IDA) | GO:0042306 | Ref:18676955

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.6%

TetraMine Data

TTHERM_00592800

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_07536.1	9.997093137033517e-262	armadillo/beta-catenin repeat family protein (562 aa)
DictyBase	DDB_G0272318	9.996907204735647e-62	DDB_G0272318 on chromosome: 2 position 1278811 to 1280712
Oxytricha	Contig20249.0.g40	4.998711177326993e-55	Armadillo/beta-catenin-like re peat
SGD	YNL189W	9.995951036711152e-55	SRP1 Karyopherin alpha homolog , forms a dimer with karyopher in beta Kap95p to mediate impo rt of nuclear proteins, binds the nuclear localization signa l of the substrate during impo rt; may also play a role in re gulation of protein degradatio n
WormBase	WBGene00002074	2.0008536325002377e-42	locus:ima-3 Importin subunit alpha-3 status:Confirmed UniProt:Q19969 protein_id:CC D70435.1
Stentor Coeruleus	SteCoe_15530	6.47023492564546e-26

General Information

No Data fetched for General Information

Associated Literature

1. Ref:18676955: Malone CD, Falkowska KA, Li AY, Galanti SE, Kanuru RC, LaMont EG, Mazzarella KC, Micev AJ, Osman MM, Piotrowski NK, Suszko JW, Timm AC, Xu MM, Liu L, Chalker DL (2008) Nucleus-specific importin alpha proteins and nucleoporins regulate protein import and nuclear division in the binucleate Tetrahymena thermophila. Eukaryotic cell 7(9):1487-99

Sequences

>TTHERM_00592800(coding)
ATGGATACTCAAATATTAGGATAAGTTAACTTATGCAAGGAAAAATTAACTTAGGAAGGA
TCTCCTTTAGAGACAATTATAGAATTGAGGAAAATGACTTCAAAGGAAGTCAGTCCTCCT
CTTTAAGAGATAATATAGTCAAATGTTTGCACTTAGCTAATAGCTATAATGGACAACACC
ACAAGCAATGAAATTATCTTGGAATCACTTTGGATTCTCACTAATGTGTGTTCAGGCAGT
AGCAGTTAGACATAATATGTTATAAATATTGGCGGTATCGCTACTTTCTTAAAGTACGTC
TAACATGAAAGCGAAGATATTATGGCTCAAGCTCTTTGGGGTTTAGGAAATATTGCTGGA
GATAGTAGCAGCAGCAGAGATTAAGTGCTCAAATAAGATGCTGTGACAATTGTTCTCAAA
TAATTAGAAAGAAAAGACATTAAAATAGTCAACTAAAGAACTATTGTTTGGGTTATTTCT
AATTTTTGTAGAGGAAAGCCTTAGCCAAAATACGAAATAGTGCGTCCTTGTGTATTTTAT
TTGGGTAAAGCTTTAGAGAAATACAAAAATGATCCAGAGATTGTTGCTGATTCTCTATGG
GGAATAAATTATCTCAGTGAAACAGAGCTAGCAATTGATGATTTAATAAATTATGGAATT
TTATAAAATATATGTTAACACTTCTTGAATTTTAATTCAACCTCAACACTAACACCTGCA
GTCAGAATTATAGGTAATGTGGCAACTTCTAGAGATAATTATGTTGATATTCTCCTTTAA
TAGAATATTCTCCAACCGTTGATACAGCTATTTGTTCATGATAAAAAAGCATACAGAAAA
GAATCTCTTTGGACTGTTTCAAATATTATGGCTGGAACTTCTACCTAGGTTTAAAAGGTT
TTAGAGCAACCAAATTTCTATCAGAATTTAATAAATAATGTGGGTTAATAGCTAGATATT
AGAAAAGAAATGCTTTATGTCATGTCAAATGGTTTAGGTCACTCTGCAGCCTGTTCTTTT
TTCTTAAAAAATGGCATCTTATAAGTGTTCTTTGAACAATTTGAAGAAGGAGATTCTAAA
ATGAAAATGGTTATTTTAGAAGGGCTTCAGCTACTCTTGAAATATGTTAATAAGAATAAG
AAAGTTTACCCCGTTTTAAACGGAAAGCTCCAATATCTTAAGAGTATTGCTACAGAAACT
ATTTATTCAAATATGGCTGATAAGTTAAAAGCTGTTTATAAACTCTTGAGAAATTATGAA
AAAATAAATCCTCCTGTAGATGCAATAAATAGCTAACTTGAGAACTTGAAAATAGACGAA
TAACAATAAAGATAAACTGAAAGCTCTTACGAAACTATTGACAATGAAGAAGATGACGAA
GAAGACATGGATGAAGAGTTTGAAGATTGCGAAGATATTGACGAAGAAGAAGAGCAATAA
AATGATGAAATATAAAATAATTTGAATAAGCAAAAAGCACAAGGAGCAAATGCAAAAGGT
AATTAAGAGTATGAAAGCATTTAAAGTAATGATAAAGACTTTTTGGGAGCAGCTGCAGGT
CCAGCAGCTCCTCCAAATTTAGATTAGCTCGAATATTAATATACAGACGAATAATAATAG
TATATGTAGGCATAGGCTGGTGCTGCACCAGGTCCATGA

>TTHERM_00592800(protein)
MDTQILGQVNLCKEKLTQEGSPLETIIELRKMTSKEVSPPLQEIIQSNVCTQLIAIMDNT
TSNEIILESLWILTNVCSGSSSQTQYVINIGGIATFLKYVQHESEDIMAQALWGLGNIAG
DSSSSRDQVLKQDAVTIVLKQLERKDIKIVNQRTIVWVISNFCRGKPQPKYEIVRPCVFY
LGKALEKYKNDPEIVADSLWGINYLSETELAIDDLINYGILQNICQHFLNFNSTSTLTPA
VRIIGNVATSRDNYVDILLQQNILQPLIQLFVHDKKAYRKESLWTVSNIMAGTSTQVQKV
LEQPNFYQNLINNVGQQLDIRKEMLYVMSNGLGHSAACSFFLKNGILQVFFEQFEEGDSK
MKMVILEGLQLLLKYVNKNKKVYPVLNGKLQYLKSIATETIYSNMADKLKAVYKLLRNYE
KINPPVDAINSQLENLKIDEQQQRQTESSYETIDNEEDDEEDMDEEFEDCEDIDEEEEQQ
NDEIQNNLNKQKAQGANAKGNQEYESIQSNDKDFLGAAAGPAAPPNLDQLEYQYTDEQQQ
YMQAQAGAAPGP

>TTHERM_00592800(gene)
ATGGATACTCAAATATTAGGATAAGTTAACTTATGCAAGGAAAAATTAACTTAGGAAGGA
TCTCCTTTAGAGACAATTATAGAATTGAGGAAAATGACTTCAAAGGAAGTCAGTCCTCCT
CTTTAAGAGATAATATAGTCAAATGTTTGCACTTAGCTAATAGCTATAATGGACAACACC
ACAAGCAATGAAATTATCTTGGAATCACTTTGGATTCTCACTAATGTGTGTTCAGGCAGT
AGCAGTTAGACATAATATGTTATAAATATTGGCGGTATCGCTACTTTCTTAAAGTACGTC
TAACATGAAAGCGAAGATATTATGGCTCAAGCTCTTTGGGGTTTAGGTAATGAACAAAAT
AGATTTAATCAAGATAGATATTTATAAATTATTTTTTTTTTGTATGAATTTATTATTAAT
TTTTGGTATTAATTATTTATTATTTTAGGAAATATTGCTGGAGATAGTAGCAGCAGCAGA
GATTAAGTGCTCAAATAAGATGCTGTGACAATTGTTCTCAAATAATTAGAAAGAAAAGAC
ATTAAAATAGTCAACTAAAGAACTATTGTTTGGGTTATTTCTAATTTTTGTAGAGGAAAG
CCTTAGCCAAAATACGAAATAGTGCGTCCTTGTGTATTTTATTTGGGTAAAGCTTTAGAG
AAATACAAAAATGATCCAGAGATTGTTGCTGATTCTCTATGGGGAATAAATTATCTCAGT
GAAACAGAGCTAGCAATTGATGATTTAATAAATTATGGAATTTTATAAAATATATGTTAA
CACTTCTTGAATTTTAATTCAACCTCAACACTAACACCTGCAGTCAGAATTATAGGTAAT
GTGGCAACTTCTAGAGATAATTATGTTGATATTCTCCTTTAATAGAATATTCTCCAACCG
TTGATACAGCTATTTGTTCATGATAAAAAAGCATACAGAAAAGAATCTCTTTGGACTGTT
TCAAATATTATGGCTGGAACTTCTACCTAGGTTTAAAAGGTTTTAGAGCAACCAAATTTC
TATCAGAATTTAATAAATAATGTGGGTTAATAGCTAGATATTAGAAAAGAAATGCTTTAT
GTCATGTCAAATGGTTTAGGTCACTCTGCAGCCTGTTCTTTTTTCTTAAAAAATGGCATC
TTATAAGTGTTCTTTGAACAATTTGAAGAAGGAGATTCTAAAATGAAAATGGTTATTTTA
GAAGGGCTTCAGCTACTCTTGAAATATGTTAATAAGAATAAGAAAGTTTACCCCGTTTTA
AACGGAAAGCTCCAATATCTTAAGAGTATTGCTACAGAAACTATTTATTCAAATATGGCT
GATAAGTTAAAAGCTGTTTATAAACTCTTGAGAAATTATGAAAAAATAAATCCTCCTGTA
GATGCAATAAATAGCTAACTTGAGAACTTGAAAATAGACGAATAACAATAAAGATAAACT
GAAAGCTCTTACGAAACTATTGACAATGAAGAAGATGACGAAGAAGACATGGATGAAGAG
TTTGAAGATTGCGAAGATATTGACGAAGAAGAAGAGCAATAAAATGATGAAATATAAAAT
AATTTGAATAAGCAAAAAGCACAAGGAGCAAATGCAAAAGGTAATTAAGAGTATGAAAGC
ATTTAAAGTAATGATAAAGACTTTTTGGGAGCAGCTGCAGGTCCAGCAGCTCCTCCAAAT
TTAGATTAGCTCGAATATTAATATACAGACGAATAATAATAGTATATGTAGGCATAGGCT
GGTGCTGCACCAGGTCCATGA