Identifiers and Description

Gene Model Identifier

TTHERM_00703970

Standard Name

IMA5 (IMportin Alpha 5)

Aliases

PreTt20173 | 110.m00146

Description

IMA5 importin subunit alpha putative; Armadillo/beta-catenin-like repeat family protein; Karyopherin/Importin alpha family member

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• micronucleus (EXP) | GO:0031040 | Ref:18676955

Biological Process

• regulation of protein import into nucleus (IDA) | GO:0042306 | Ref:18676955

Domains

• ( PF01749 ) Importin beta binding domain
• ( PF00514 ) Armadillo/beta-catenin-like repeat

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.3%

TetraMine Data

TTHERM_00703970

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_15263.1	4.99929489534828e-74	hypothetical protein (300 aa)
DictyBase	DDB_G0272318	0.00000000000020009182674645818	DDB_G0272318 on chromosome: 2 position 1278811 to 1280712
SGD	YNL189W	0.000000000007996637300921877	SRP1 Karyopherin alpha homolog , forms a dimer with karyopher in beta Kap95p to mediate impo rt of nuclear proteins, binds the nuclear localization signa l of the substrate during impo rt; may also play a role in re gulation of protein degradatio n
WormBase	WBGene00002074	0.00000000030007160092483236	locus:ima-3 Importin subunit alpha-3 status:Confirmed UniProt:Q19969 protein_id:CC D70435.1
Oxytricha	Contig20249.0.g40	0.000000000500206551404915	Armadillo/beta-catenin-like re peat

General Information

No Data fetched for General Information

Associated Literature

1. Ref:18676955: Malone CD, Falkowska KA, Li AY, Galanti SE, Kanuru RC, LaMont EG, Mazzarella KC, Micev AJ, Osman MM, Piotrowski NK, Suszko JW, Timm AC, Xu MM, Liu L, Chalker DL (2008) Nucleus-specific importin alpha proteins and nucleoporins regulate protein import and nuclear division in the binucleate Tetrahymena thermophila. Eukaryotic cell 7(9):1487-99

Sequences

>TTHERM_00703970(coding)
ATGATGCAAGAAATATTTTAAAATTAGCAACTTCCTACATTCGAAACTTATTAGCAAAAT
ATTGAATAGGATTAAGAAGATGTCAAATAAGTAATATCCAAAAAGAGAGAGTAATTCTAG
GTTTAAATCAGAAAAGGAAAGAGAGATGAAATACTCAATAGAAAAAGAGTTGAAAAAATG
AATATTCTAAAATAAAGTTTAGAAGATAAGCTAAAAGGTTTTCACTTAATCTACGAGGAG
CAATCAGTTATTCCATTGATTAAAAATATTTAGGGTCAAGACATCGATTTAGATGTGCCA
GTTAGAATGCAGCAAATGCTAAGTTAAATAAATTATTTAAATGTGGAATCTTCCTAATAA
AAGTAGTTAGAATAATCTATTTTAACTCCAAACACTCCCGAAGATCTTCTAGTTTCTTTC
AAAAAGTATCGCTATTTGATTTTAGAGGAAAAAGTTTTGTGTGCTGACATTGATCTAAAT
CTTTCAGAAAAGTTAGTCTAAATGTTAACCTAGTTGCAATAATACCCAGCAATAATATAT
GAAGTTGTTTAATTACTTTCAATAATAAGCTCTGGGACCAGAAAGCAAGTTGATAGCATA
ATTAATATAGGCGGTGTAAATGTTATAGATAATATTTTTAATTCATACGATTACTCCGTG
CTTATTCAAGAACAACTAGTGGAAGTTATAGGAAATTTAATAGCAGACTAGCAGATTAAT
CGCGATTTGATAATGAAATCAGGTATTATAGATAAAATACTTGCAGCTAATCATAAAGAT
ATTCTTTATATTAGAACTGCGATATGGGCTATATGCAATATTTGCTGTATGAAAGAATTT
TGCAAATTTTGCGATATGTAATGTTTTTTGCCTACCTTTTTAAACATTATTAAACTCTAT
CCAACTGACAAGCAACTTGTAAGTGATAGTCTATTGTCTCTATCTATATTAGCAAAACAA
GCAACGAGATTAGATGAACTAGAGTTGTTTTGCAGTGAAGAACTAGCTGAATGTCTGAAA
ATAAATTTATAAGCTCCAATTAATTCCATAAGAGAAAGGGCATTGAAGATATTAACAAAT
CTCACAGAAAAGAAACATATCTCAGGTGTTTCCTCTTGCATATATAGCAATAAATTTGAT
TAAAATATAATCTAAGAGCTGCTACTTAAGCATTATAAAAAAGAAAATAAAAAAGCAAAA
TAGGTCGTTGAAAATTCAGATTCAAATGGAATGCAAGTAATTAATGAAGGTTTACAAATA
TGTAGTAACTTCTCTACTAGAAAATATGCAATTATAGCTATTTAAAATCTAATTGAAAAA
GACGACAGATATCTCAGCTATCTTCTCGAAAGTTAAAACTTGATTTAAGTTCTCGTCAAT
ACTCTTTTAAAAGAATAAAAACAAGATAACATCGTTTCAGTACTTTATATTCTGGAGTCA
ATTTTCTATGATAAAAAATATGGCATTGTTGACAGTTTATTAGATTCTTAATTTTTTGAG
GCCCTTTATTACTTACTTGACTATTAAGAAAAAGACATTCTTTAAATTTGTCTCTAATTG
GTTTATGATATTCTATGCTTTTTATAAAATTTACAAAACAATAATATCATGTAAGAAGAT
TTTATTAACACGAGAAATAATCTAGAAAGTGCAATTGATAAAATAAATGACTATGGAGTT
ATTAAAAAAATTATTGAATTATAAGGTAACAGGTCAAAAGATGTCAGTGAAATATCCATG
GATATATTGGATAAATTTTTCCCTGACATTTAGTGA

>TTHERM_00703970(protein)
MMQEIFQNQQLPTFETYQQNIEQDQEDVKQVISKKREQFQVQIRKGKRDEILNRKRVEKM
NILKQSLEDKLKGFHLIYEEQSVIPLIKNIQGQDIDLDVPVRMQQMLSQINYLNVESSQQ
KQLEQSILTPNTPEDLLVSFKKYRYLILEEKVLCADIDLNLSEKLVQMLTQLQQYPAIIY
EVVQLLSIISSGTRKQVDSIINIGGVNVIDNIFNSYDYSVLIQEQLVEVIGNLIADQQIN
RDLIMKSGIIDKILAANHKDILYIRTAIWAICNICCMKEFCKFCDMQCFLPTFLNIIKLY
PTDKQLVSDSLLSLSILAKQATRLDELELFCSEELAECLKINLQAPINSIRERALKILTN
LTEKKHISGVSSCIYSNKFDQNIIQELLLKHYKKENKKAKQVVENSDSNGMQVINEGLQI
CSNFSTRKYAIIAIQNLIEKDDRYLSYLLESQNLIQVLVNTLLKEQKQDNIVSVLYILES
IFYDKKYGIVDSLLDSQFFEALYYLLDYQEKDILQICLQLVYDILCFLQNLQNNNIMQED
FINTRNNLESAIDKINDYGVIKKIIELQGNRSKDVSEISMDILDKFFPDIQ

>TTHERM_00703970(gene)
ATGATGCAAGAAATATTTTAAAATTAGCAACTTCCTACATTCGAAACTTATTAGCAAAAT
ATTGAATAGGATTAAGAAGGTAAAATTTATTAATTTAGTTGTTAGATTGTTAGTAAATAT
TTGAATTGTATGATTAAAAAGATGTCAAATAAGTAATATCCAAAAAGAGAGAGTAATTCT
AGGTTTAAATCAGAAAAGGAAAGAGAGATGAAATACTCAATAGAAAAAGAGTTGAAAAAA
TGAATATTCTAAAATAAAGTTTAGAAGATAAGCTAAAAGGTTTTCACTTAATCTACGAGG
AGCAATCAGTTATTCCATTGATTAAAAATATTTAGGGTCAAGACATCGATTTAGATGTGC
CAGTTAGAATGCAGCAAATGCTAAGTTAAATAAATTATTTAAATGTGGAATCTTCCTAAT
AAAAGTAGTTAGAATAATCTATTTTAACTCCAAACACTCCCGAAGATCTTCTAGTTTCTT
TCAAAAAGTATCGCTATTTGATTTTAGAGGAAAAAGTTTTGTGTGCTGACATTGATCTAA
ATCTTTCAGAAAAGTTAGTCTAAATGTTAACCTAGTTGCAATAATACCCAGCAATAATAG
TAAATTACTTTCTTATTTTCACTTAGCTATAACAAATATTGAAACGATATACAAAAGAAT
AATCTTAATTATTCTCTTTATATTGGTATTGCTCTTTTGGAATTTAAATGAAATACTTTT
AAAAAAATAGTATGAAGTTGTTTAATTACTTTCAATAATAAGCTCTGGGACCAGAAAGCA
AGTTGATAGCATAATTAATATAGGCGGTGTAAATGTTATAGATAATATTTTTAATTCATA
CGATTACTCCGTGCTTATTCAAGAACAACTAGTGGAAGTTATAGGAAATTTAATAGCAGA
CTAGCAGATTAATCGCGATTTGATAATGAAATCAGGTATTATAGATAAAATACTTGCAGC
TAATCATAAAGATATTCTTTATATTAGAACTGCGATATGGGCTATATGCAATATTTGCTG
TATGAAAGAATTTTGCAAATTTTGCGATATGTAATGTTTTTTGCCTACCTTTTTAAACAT
TATTAAACTCTATCCAACTGACAAGCAACTTGTAAGTGATAGTCTATTGTCTCTATCTAT
ATTAGCAAGTAAATCTATTTGTCTAAATAAATTATCTTTTTAAATAACTTTTTTTTAACA
GAACAAGCAACGAGATTAGATGAACTAGAGTTGTTTTGCAGTGAAGAACTAGCTGAATGT
CTGAAAATAAATTTATAAGCTCCAATTAATTCCATAAGAGAAAGGGCATTGAAGATATTA
ACAAATCTCACAGAAAAGAAACATATCTCAGGTGTTTCCTCTTGCATATATAGCAATAAA
TTTGATTAAAATATAATCTAAGAGCTGCTACTTAAGCATTATAAAAAAGAAAATAAAAAA
GCAAAATAGGTCGTTGAAAATTCAGATTCAAATGGAATGCAAGTAATTAATGAAGGTTTA
CAAATATGTAGTAACTTCTCTACTAGAAAATATGCAATTATAGCTATTTAAAATCTAATT
GAAAAAGACGACAGATATCTCAGCTATCTTCTCGAAAGTTAAAACTTGATTTAAGTTCTC
GTCAATACTCTTTTAAAAGAATAAAAACAAGATGTAAAAATAATTTCATATTTTAAAATA
AATTTAAATAATTTTTATTTTAATATAGAACATCGTTTCAGTACTTTATATTCTGGAGTC
AATTTTCTATGATAAAAAATATGGCATTGTTGACAGTTTATTAGATTCTTAATTTTTTGA
GGCCCTTTATTACTTACTTGACTATTAAGAAAAAGACATTCTTTAAATTTGTCTCTAATT
GGTTTATGATATTCTATGCTTTTTATAAAATTTACAAAACAATAATATCATGTAAGAAGA
TTTTATTAACACGAGAAATAATCTAGAAAGTGCAATTGATAAAATAAATGACTATGGAGT
TATTAAAAAAATTATTGAATTATAAGGTAACAGGTCAAAAGATGTCAGTGAAATATCCAT
GGATATATTGGATAAATTTTTCCCTGACATTTAGTGA