Identifiers and Description

Gene Model Identifier

TTHERM_00621200

Standard Name

IMA2 (Importin Alpha 2)

Aliases

PreTt05117 | 86.m00149

Description

Armadillo/beta-catenin-like repeat family protein; Karyopherin/Importin alpha family member

Genome Browser (Macronucleus)

GBrowse

Genome Browser (Micronucleus)

GBrowse

Gene Ontology Annotations

Cellular Component

Domains

  • ( PF02985 ) HEAT repeat
  • ( PF00514 ) Armadillo/beta-catenin-like repeat

Gene Expression Profile

  • Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.2%

TetraMine Data

TTHERM_00621200

WebApollo

Fullscreen View

Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

SourceIdentifierScoreDescription
Tetrahymena borealisEI9_03063.19.997093137033517e-262armadillo/beta-catenin repeat
family protein (583 aa)
DictyBaseDDB_G02723183.999672240330216e-26DDB_G0272318 on chromosome: 2
position 1278811 to 1280712
OxytrichaContig20249.0.g401.0002869940498747e-21Armadillo/beta-catenin-like re
peat
SGDYNL189W7.998763385146868e-21SRP1 Karyopherin alpha homolog
, forms a dimer with karyopher
in beta Kap95p to mediate impo
rt of nuclear proteins, binds
the nuclear localization signa
l of the substrate during impo
rt; may also play a role in re
gulation of protein degradatio
n
WormBaseWBGene000020740.00000000000001000191320216021locus:ima-3 Importin subunit
alpha-3 status:Confirmed
UniProt:Q19969 protein_id:CC
D70435.1

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:18676955: Malone CD, Falkowska KA, Li AY, Galanti SE, Kanuru RC, LaMont EG, Mazzarella KC, Micev AJ, Osman MM, Piotrowski NK, Suszko JW, Timm AC, Xu MM, Liu L, Chalker DL (2008) Nucleus-specific importin alpha proteins and nucleoporins regulate protein import and nuclear division in the binucleate Tetrahymena thermophila. Eukaryotic cell 7(9):1487-99

Sequences

>TTHERM_00621200(coding)
ATGGATATTGGATAAGACGAGGCACAACTGGTATTGTAGCATAAAAAAGATTAGTTTAGA
GTAGAGATTCGTAAGAAAAAGACAGATAGTTTAATATAGTAGAAAAGATTAAAGCTATTT
AATAAGAATTTAACAAATTTAGATAGCTTTTCTGATGCTGACAACAGTAAAAGCGATCAG
AATACTACTCAAGATCCTTAGAACAACATTTTAAGTTAACAACAAATTTAACAATAATAA
GTGTCTACTTTAGATGTTTAAGTCATTCGTGATATAGAAAGTAGGCTTTTGCAATGTTAG
AAAGATAATAATATAGAATAAATGAGATCTATTTTAATTCAGCTCGTTAAAATTGTTGGA
ACTTACCCATCACCAATAAATTAAATGTTTATGACAAGCTTACCTAAATTTGTAATTTCT
ATTGTTAATAAGCATGGCCCAGTAAATGATCCTAAATGTAAAAATTATGCTGCTCACATC
TTGGCAAATCTCACTGCAGGTACTCCTATGTAGTTGTAAGAACTTTTTTAGCTAGATTTG
ATTCACATCTTAATAGAGTAAATCCAATCCAAGGATGTAGAGTTAGCAGATCATGTCATT
TGGGCTTTTAATAATGTCTTGATTGATAATCATTAACCAGAGAACCTTGTAAGAATATTC
TAAGAGCGCCCTTTGATAATTGAAGATTTGTGCTATTATTTCACCACTTCTTGTAATAAT
CCAAATATCTAGTTTTAGCTTATTAGCTCAGTAATTCTTTCGATTTACTGTCTTTCTAGA
ATCCATAAAACTACTTAATCATATTATAATTAATTGAGGATTGCTATCCCATATCTAGCA
AAATTATTAGATGTCCATCATCCAAAAGAACCAAACACAGTAATAAATAGCATGTCTTCG
CTCCCTAATAAAAATAAATCAATGATTTTGAGCAATAATAGCAATTAGAATTAAATGAAT
TCCGAAAATTGTAAACCAACTAATTTATAAAGCACAAATAGTAATATCTAAAAAAGTGAC
TAGCAAGTTAAGTAAAAATTTCTCTGTTCTGTAGATTTAAAAATGTGCGCTCTTATAATA
ACGGATTTAAGTGAAGGTGATCCAAGAGTTATTAGCGATATGCTTAAAATTTAAGTTGAT
AGAATTATGCTTAGATATTTAGAGTAGGGAATTGATGTTAATGAGCATTTCCTCACCTTT
GTAATAAGAACTCTAGCCAACATGTCTAGTGGAAACGAGTTTCAAACTGACTAACTTCTC
TAAAAGGATATTTATTCATATCTGAACAGATTTTTGGAACATCCAAAAGAATAGATCAGA
AAAGATGTTTGTTGGCTAATAAGCAATTTGTCAGCAGGAAATGCTTCTCAAATAGATGTA
TTTTTAAATAAGAATATGCTTTAAACTTTGATTCAAAGACTTAACGTAGAGTAGAGCATA
CATGTAAAAAAAGAGATACTGTTTGCTCTGAGTAACGCAACTGCACAAGCAACAAAAGAA
CAAATAAATAAAATGGTTTCTAATGGTTTATTGAGAGTTTTTTCAGATAACCTCGACCCC
TAGTATGAAACTGAATTGCTTATTGAAATTTTAGAAGGAATAGAAAATGTAATGATGTTA
GGTCGTTCTGATGACCTCAATAATAATTAAAATGCATATAGCCATGAATTTGAAGGATCT
GGATGTTAAAGAAAAATCCAATATTTATATTACTAAAAATCAGACCAAACAGTAGTTGAA
ATTTCTGATAGAATACTCCGTTCATATGGAACTAATTGA


>TTHERM_00621200(protein)
MDIGQDEAQLVLQHKKDQFRVEIRKKKTDSLIQQKRLKLFNKNLTNLDSFSDADNSKSDQ
NTTQDPQNNILSQQQIQQQQVSTLDVQVIRDIESRLLQCQKDNNIEQMRSILIQLVKIVG
TYPSPINQMFMTSLPKFVISIVNKHGPVNDPKCKNYAAHILANLTAGTPMQLQELFQLDL
IHILIEQIQSKDVELADHVIWAFNNVLIDNHQPENLVRIFQERPLIIEDLCYYFTTSCNN
PNIQFQLISSVILSIYCLSRIHKTTQSYYNQLRIAIPYLAKLLDVHHPKEPNTVINSMSS
LPNKNKSMILSNNSNQNQMNSENCKPTNLQSTNSNIQKSDQQVKQKFLCSVDLKMCALII
TDLSEGDPRVISDMLKIQVDRIMLRYLEQGIDVNEHFLTFVIRTLANMSSGNEFQTDQLL
QKDIYSYLNRFLEHPKEQIRKDVCWLISNLSAGNASQIDVFLNKNMLQTLIQRLNVEQSI
HVKKEILFALSNATAQATKEQINKMVSNGLLRVFSDNLDPQYETELLIEILEGIENVMML
GRSDDLNNNQNAYSHEFEGSGCQRKIQYLYYQKSDQTVVEISDRILRSYGTN


>TTHERM_00621200(gene)
ATGGATATTGGATAAGACGAGGCACAACTGGTATTGTAGCATAAAAAAGATTAGTTTAGA
GTAGAGATTCGTAAGAAAAAGACAGATAGTTTAATATAGTAGAAAAGATTAAAGCTATTT
AATAAGAATTTAACAAATTTAGATAGCTTTTCTGATGCTGACAACAGTAAAAGCGATCAG
AATACTACTCAAGATCCTTAGAACAACATTTTAAGTTAACAACAAATTTAACAATAATAA
GTGTCTACTTTAGATGTTTAAGTCATTCGTGATATAGAAAGTAGGCTTTTGCAATGTTAG
AAAGATAATAATATAGAATAAATGAGATCTATTTTAATTCAGCTCGTTAAAATTGTTGGA
ACTTACCCATCACCAATAAATTAAATGTTTATGACAAGCTTACCTAAATTTGTAATTTCT
ATTGTTAATAAGCATGGCCCAGTAAATGATCCTAAATGTAAAAATTATGCTGCTCACATC
TTGGCAAATCTCACTGCAGGTACTCCTATGTAGTTGTAAGAACTTTTTTAGCTAGATTTG
ATTCACATCTTAATAGAGTAAATCCAATCCAAGGATGTAGAGTTAGCAGATCATGTCATT
TGGGCTTTTAATAATGTCTTGATTGATAATCATTAACCAGAGAACCTTGTAAGAATATTC
TAAGAGCGCCCTTTGATAATTGAAGATTTGTGCTATTATTTCACCACTTCTTGTAATAAT
CCAAATATCTAGTTTTAGCTTATTAGCTCAGTAATTCTTTCGATTTACTGTCTTTCTAGA
ATCCATAAAACTACTTAATCATATTATAATTAATTGAGGATTGCTATCCCATATCTAGCA
AAATTATTAGATGTCCATCATCCAAAAGAACCAAACACAGTAATAAATAGCATGTCTTCG
CTCCCTAATAAAAATAAATCAATGATTTTGAGCAATAATAGCAATTAGAATTAAATGAAT
TCCGAAAATTGTAAACCAACTAATTTATAAAGCACAAATAGTAATATCTAAAAAAGTGAC
TAGCAAGTTAAGTAAAAATTTCTCTGTTCTGTAGATTTAAAAATGTGCGCTCTTATAATA
ACGGATTTAAGTGAAGGTGATCCAAGAGTTATTAGCGATATGCTTAAAATTTAAGTTGAT
AGAATTATGCTTAGATATTTAGAGTAGGGAATTGATGTTAATGAGCATTTCCTCACCTTT
GTAATAAGAACTCTAGCCAACATGTCTAGTGGAAACGAGTTTCAAACTGACTAACTTCTC
TAAAAGGATATTTATTCATATCTGAACAGATTTTTGGAACATCCAAAAGAATAGATCAGA
AAAGATGTTTGTTGGCTAATAAGCAATTTGTCAGCAGGAAATGCTTCTCAAATAGATGTA
TTTTTAAATAAGAATATGCTTTAAACTTTGATTCAAAGACTTAACGTAGAGTAGAGCATA
CATGTAAAAAAAGAGATACTGTTTGCTCTGAGTAACGCAACTGCACAAGCAACAAAAGAA
CAAATAAATAAAATGGTTTCTAATGGTTTATTGAGAGTTTTTTCAGATAACCTCGACCCC
TAGTATGAAACTGAATTGCTTATTGAAATTTTAGAAGGAATAGAAAATGTAATGATGTTA
GGTCGTTCTGATGACCTCAATAATAATTAAAATGCATATAGCCATGAATTTGAAGGATCT
GGATGTTAAAGAAAAATCCAATATTTATATTACTAAAAATCAGACCAAACAGTAGTTGAA
ATTTCTGATAGAATACTCCGTTCATATGGAACTAATTGA