Identifiers and Description

Gene Model Identifier

TTHERM_00938930

Standard Name

IMA12 (Importin Alpha 12)

Aliases

PreTt03743 | 170.m00072

Description

IMA12 armadillo/beta-catenin repeat protein; Armadillo/beta-catenin-like repeat family protein; Karyopherin/Importin alpha family member

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• micronucleus (EXP) | GO:0031040 | Ref:18676955

Domains

• ( PF02985 ) HEAT repeat
• ( PF00514 ) Armadillo/beta-catenin-like repeat
• ( PF09324 ) Domain of unknown function (DUF1981)

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.5%

TetraMine Data

TTHERM_00938930

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_19350.1	9.997093137033517e-262	armadillo/beta-catenin repeat family protein (540 aa)
SGD	YNL189W	0.000005000363240844623	SRP1 Karyopherin alpha homolog , forms a dimer with karyopher in beta Kap95p to mediate impo rt of nuclear proteins, binds the nuclear localization signa l of the substrate during impo rt; may also play a role in re gulation of protein degradatio n
DictyBase	DDB_G0273595	1	DDB_G0273595 on chromosome: 2 position 3154181 to 3155997

General Information

No Data fetched for General Information

Associated Literature

1. Ref:18676955: Malone CD, Falkowska KA, Li AY, Galanti SE, Kanuru RC, LaMont EG, Mazzarella KC, Micev AJ, Osman MM, Piotrowski NK, Suszko JW, Timm AC, Xu MM, Liu L, Chalker DL (2008) Nucleus-specific importin alpha proteins and nucleoporins regulate protein import and nuclear division in the binucleate Tetrahymena thermophila. Eukaryotic cell 7(9):1487-99

Sequences

>TTHERM_00938930(coding)
ATGGAGGAAATTTACTAAGGCTAAGAAATCTATGAAGATGAAGATAGGGATGTTATACAA
GAAGCCATAAAGGCAAAGAAAGAGAAATTTAGGATATAGATTAGGTAATCTAAGAATAAA
CAGCTGATATAGCAAAAGAGAATGAAATTATTAAATGGTTAGTAGCATTAACCAAAAAAT
TATTATGAAGTAGATAAATAAGATAATCAAGGATTTAAAAATAACAATAAAGAATATGAA
ATTTAACTATCACTATTAAAGGAAAATATCAAAATTTTGCTTTCGCTCAATTAGCATTCA
AAACAATAAGCCCAAGTAGCTGTTGATAGTTTGATAGCTTATTTATTAGATGGATCTTAT
AACTAAGATATTGAATAGCTAACACAAATATCAAGTACAATATAATATTTAATAGTCTTA
GGATAATAGCCAAATTGTGATTTTAATGACTAAGAGCTTGCTAAAAGTGCATTAGCTCTT
CTCCTTAATATTACATATTATTGCGATTAACAGCAAATGAAATACTTTTCTAATTAAGAC
ATTATGAATTCCTTACTTTAGCTATTATACTCAGAAAGCATGCAGATAAGAGAATATTGT
TTAACAACAATTAACAATATTATCCAAGAAGATGTAGATAATATCAAGTTTCTAATGGAA
AGATTTATTGCACAAGAAATTATAAGCCTTGTTACTACATATCCAATCTCAAATGAAATT
GTTTTAGATCTTTCTTCAATAATAAAATAAATTGTCATTCAAAGCAGTATTGTATATTCT
GAGGCCACTGAATTTTTAATCCCTATTGATGAGTTAATTGAGATTCATTTGTCTTCATAA
TTAAATGAAGAATCAGATAACACAGCTTTAAATAATTTATTAGAAAGTATTTATACTATT
TTGAACAAAGAAGATTCTGAAGATATTTATGAGAATTTCGTTTTAGAATATTAAAGATTA
TTAGCAAATATGATTGAAATAGTTAAACAGATATAGTTAAATTAAAAATTTAATAGCATT
GCTATTAATATATCATAAATATTTGGCTTACTTTTATCAGGAAACATCAAAACTACATAA
ATTTTAGTGCAAAATGATATTTTTGAGTCTTTAAAAATATTAATCAAGCATCCAAAAAAA
GAGGTTAGATCAGAATCTATGTGGGCTGTTTCAAATTTATTTGTTTTTTCTAATGTTGAA
GGGCTAAAAGAGTATTTAAGTGATTTAATTTTCTGGGAATCTATTTTAGATTCTGCTTTC
TAAGATCATAAAAGTGTAAGAAAATGGGCTTACGTTTCTATATTAAATGCATTAATAATA
AACGACATAGAGTTCATAGAAATTATTTTGGAAAGATTTCCTGAATCAGATTTAATAAAA
TTTATATTTGAAAAAATTGAAGATAAAGATTATCAAAATGTTTTGGTATCTTTACTTGAA
GCAGTTAAATCTTTAATAAGTTATGGTGAATATTGTTAAAATTAAAACAATTACGAAGAA
AACCACATATTATCTCTTATATAAAGAATTAACTCAAAACAAATTATTTAGTAGATTCAA
AATAACCCAGATAACGACTTGTATAGTGTTTCTTCATATTTGCTGGATAAAATTTAATGA

>TTHERM_00938930(protein)
MEEIYQGQEIYEDEDRDVIQEAIKAKKEKFRIQIRQSKNKQLIQQKRMKLLNGQQHQPKN
YYEVDKQDNQGFKNNNKEYEIQLSLLKENIKILLSLNQHSKQQAQVAVDSLIAYLLDGSY
NQDIEQLTQISSTIQYLIVLGQQPNCDFNDQELAKSALALLLNITYYCDQQQMKYFSNQD
IMNSLLQLLYSESMQIREYCLTTINNIIQEDVDNIKFLMERFIAQEIISLVTTYPISNEI
VLDLSSIIKQIVIQSSIVYSEATEFLIPIDELIEIHLSSQLNEESDNTALNNLLESIYTI
LNKEDSEDIYENFVLEYQRLLANMIEIVKQIQLNQKFNSIAINISQIFGLLLSGNIKTTQ
ILVQNDIFESLKILIKHPKKEVRSESMWAVSNLFVFSNVEGLKEYLSDLIFWESILDSAF
QDHKSVRKWAYVSILNALIINDIEFIEIILERFPESDLIKFIFEKIEDKDYQNVLVSLLE
AVKSLISYGEYCQNQNNYEENHILSLIQRINSKQIIQQIQNNPDNDLYSVSSYLLDKIQ

>TTHERM_00938930(gene)
ATGGAGGAAATTTACTAAGGCTAAGAAATCTATGAAGATGAAGATAGGGATGTTATACAA
GAAGCCATAAAGGCAAAGAAAGAGAAATTTAGGATATAGATTAGGTAATCTAAGAATAAA
CAGCTGATATAGCAAAAGAGAATGAAATTATTAAATGGTTAGTAGCATTAACCAAAAAAT
TATTATGAAGTAGATAAATAAGATAATCAAGGATTTAAAAATAACAATAAAGAATATGAA
ATTTAACTATCACTAGTAAATTTTTAGTATTATGAAAAAATTATTTATTTAATCTCTATA
TAAAGTTAAAGGAAAATATCAAAATTTTGCTTTCGCTCAATTAGCATTCAAAACAATAAG
CCCAAGTAGCTGTTGATAGTTTGATAGCTTATTTATTAGATGGATCTTATAACTAAGATA
TTGAATAGCTAACACAAATATCAAGTACAATATAATATTTAATAGTCTTAGGATAATAGC
CAAATTGTGATTTTAATGACTAAGAGCTTGCTAAAAGTGCATTAGCTCTTCTCCTTAATA
TTACATATTATTGCGATTAACAGCAAATGAAATACTTTTCTAATTAAGACATTATGAATT
CCTTACTTTAGCTATTATACTCAGAAAGCATGCAGATAAGAGAATATGTATTTATAAATT
AATAAATATTTATATGAAATAATATTTTTTAAATTGCTATTATTAAAAGTGTTTAACAAC
AATTAACAATATTATCCAAGAAGATGTAGATAATATCAAGTTTCTAATGGAAAGATTTAT
TGCACAAGAAATTATAAGCCTTGTTACTACATATCCAATCTCAAATGAAATTGTTTTAGA
TCTTTCTTCAATAATAAAATAAATTGTCATTCAAAGCAGTATTGTATATTCTGAGGTAAA
TCAATTAAAATTTATTCAAAAAATAAAATATTAAATTAAAAAATATTTAGGCCACTGAAT
TTTTAATCCCTATTGATGAGTTAATTGAGATTCATTTGTCTTCATAATTAAATGAAGAAT
CAGATAACACAGCTTTAAATAATTTATTAGAAAGTATTTATACTATTTTGAACAAAGAAG
ATTCTGAAGATATTTATGAGAATTTCGTTTTAGAATATTAAAGATTATTAGCAAATATGA
TTGAAATAGTTAAACAGATATAGTTAAATTAAAAATTTAATAGCATTGCTATTAATATAT
CATAAATATTTGGCTTACTTTTATCAGGAAACATCAAAACTACATAAGTAATTTTTTAAA
GTAAAAATAATAATAAAATATATTTATTTATTTATTTTAAATTTTATTCAGATTTTAGTG
CAAAATGATATTTTTGAGTCTTTAAAAATATTAATCAAGCATCCAAAAAAAGAGGTTAGA
TCAGAATCTATGTGGGCTGTTTCAAATTTATTTGTTTTTTCTAATGTTGAAGGGCTAAAA
GAGTATTTAAGTGATTTAATTTTCTGGGAATCTATTTTAGATTCTGCTTTCTAAGATCAT
AAAAGTGTAATTCTTAAATAAACTATTTATTTTTTAATTTTATCTATTTAAATAGGTAAG
AAAATGGGCTTACGTTTCTATATTAAATGCATTAATAATAAACGACATAGAGTTCATAGA
AATTATTTTGGAAAGATTTCCTGAATCAGATTTAATAAAATTTATATTTGAAAAAATTGA
AGATAAAGATTATCAAAATGTTTTGGTATCTTTACTTGAAGCAGTTAAATCTTTAATAAG
TTATGGTGAATATTGTTAAAATTAAAACAATTACGAAGAAAACCACATATTATCTCTTAT
ATAAAGAATTAACTCAAAACAAATTATTTAGTAGATTCAAAATAACCCAGATAACGACTT
GTATAGTGTTTCTTCATATTTGCTGGATAAAATTTAATGA