Identifiers and Description

Gene Model Identifier

TTHERM_00185260

Standard Name

IMA11 (Importin Alpha 11)

Aliases

PreTt29848 | 14.m00415

Description

Armadillo/beta-catenin-like repeat family protein; Karyopherin/Importin alpha family member

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• micronucleus (EXP) | GO:0031040 | Ref:18676955

Domains

• ( PF09090 ) MIF4G like
• ( PF02985 ) HEAT repeat
• ( PF00514 ) Armadillo/beta-catenin-like repeat

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.2%

TetraMine Data

TTHERM_00185260

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_09933.1	9.997093137033517e-262	hypothetical protein (522 aa)
Oxytricha	Contig20249.0.g40	3.9989916100764785e-24	Armadillo/beta-catenin-like re peat
DictyBase	DDB_G0272318	4.0006511639687014e-23	DDB_G0272318 on chromosome: 2 position 1278811 to 1280712
SGD	YNL189W	5.002171138422328e-22	SRP1 Karyopherin alpha homolog , forms a dimer with karyopher in beta Kap95p to mediate impo rt of nuclear proteins, binds the nuclear localization signa l of the substrate during impo rt; may also play a role in re gulation of protein degradatio n
WormBase	WBGene00002074	2.9992476920535046e-16	locus:ima-3 Importin subunit alpha-3 status:Confirmed UniProt:Q19969 protein_id:CC D70435.1
Stentor Coeruleus	SteCoe_15530	0.000000000013887943864964021

General Information

No Data fetched for General Information

Associated Literature

1. Ref:18676955: Malone CD, Falkowska KA, Li AY, Galanti SE, Kanuru RC, LaMont EG, Mazzarella KC, Micev AJ, Osman MM, Piotrowski NK, Suszko JW, Timm AC, Xu MM, Liu L, Chalker DL (2008) Nucleus-specific importin alpha proteins and nucleoporins regulate protein import and nuclear division in the binucleate Tetrahymena thermophila. Eukaryotic cell 7(9):1487-99

Sequences

>TTHERM_00185260(coding)
ATGGAAACTAATGTAGAAAATAATATAGCTGATGAAATAGATGAAGCTAAGTATATTATC
AGTAAAAAGAAGGAGATATTTAGAAAGTAAATTAGAGCCAAAAAGCATAATGAATTGTTC
CATAAAAAGAGATTTGAGCTTTTAAATTAGGACAAATCTTCTAGCAAAGAACCTATTGAT
TAAATGATGTCTACTGAAAATGCTATGCCTTCAGTATTATAAGAAATTATAATTAACCAA
AAGCATCTTTAAGATTACTTAGATAAGATTTGCGGTGACATTAAGAGTTAATATTTGAGG
AACGAAGTGGATAGTCCTGATTTGGCAAAAAATATTAAAATATTAAAACTCTACACATCT
AAAATTGATGAATATCCTCATATTGCTACTTGTGTGCTGGATAATAAAATTATTTAAACT
TTGCAATAAATCTTAACAGTTCCTTCACTAAATATAAAAAATCTATAACTAGACACAGCT
TAGATAATTTCTAACCTTACTTATTCAGATGCTGACAACATAGAAAAAATATTAGAAAAT
AATTTATCTTTAATTGATATTCTAGTTCAAGTGCTAAAAGACTAAGACAACCAATACTCA
ACTCATGCAATATATTGTTTAGCCAATATGTCTTAAGAATATTTAGATGTTAGAGACGAA
GCACTTAAAAGAGGAGTTTCTGAATGCATTATAGAAAAATATAAACAAAATAAAGCAAAT
AAAGCTTTTGTTGAGTAATTAATTTGGTTTATTGCTATCTTTAGTGTAAGACCTCACCCC
TATGAATTAATAAGAGGCTTTATACCAATATTGGATGAATAACTTGGACTACAAGGCTAA
AGCTAAGAAAATATTAAATACATTACTTTTGCTTTGAAAAATTTGAGTGAAGGTGATGAA
GATAAAATATAGTAAATTTTATAAATGAAAAATATTAAAAAGCTGCTCTATTTGTCAAGC
AAAGGCTAAGATAAAGTACCTTAGAATATTTACTAGATCATAACAAACTTGACTTTTGGA
AATGTGGATTAAATTATGTAATTAATTAATTTAGAGGTTCTTGATCACTTGAGCTATGGA
TTTGAAAAGATTAGTAAAAACATAAAAATTGAAGTTTGCTAGTCGATTAATAATTTAATG
TGTTCTAGCTACTAGGCCATAGAGCACATATTGAATCATAGATATTTACTTTCTAAAATT
TTGGCATATATTTAAACAGGAAATTTTATTTATAAAAAAGAATTAATATTAGCGTTTGGC
AACTTTTGCATACATGGAACATCATCACAAATTAATTTTATGAGATAAAGAGGTCTTTTT
TCAATTTTGATGGATAGCTTTTAATATGAAGATTCAGAAATTACTCTAAGCACACTAGAA
GGTATTTATAGGTTATTGGAACTTGGTAAAGAGTTCTAAAGAAGCTAACAAAACTATGAT
GGCAATCAGGTTTTATTAGCTTTTGAAAATTTAGGCTTATCTAATAGTTTAATGAGCTTG
TAAAAAGATCCAAATGAAAGAATTTATGAAAAATGTGAGTAAATTATACTCAATTTCTAC
GAATACTAATGA

>TTHERM_00185260(protein)
METNVENNIADEIDEAKYIISKKKEIFRKQIRAKKHNELFHKKRFELLNQDKSSSKEPID
QMMSTENAMPSVLQEIIINQKHLQDYLDKICGDIKSQYLRNEVDSPDLAKNIKILKLYTS
KIDEYPHIATCVLDNKIIQTLQQILTVPSLNIKNLQLDTAQIISNLTYSDADNIEKILEN
NLSLIDILVQVLKDQDNQYSTHAIYCLANMSQEYLDVRDEALKRGVSECIIEKYKQNKAN
KAFVEQLIWFIAIFSVRPHPYELIRGFIPILDEQLGLQGQSQENIKYITFALKNLSEGDE
DKIQQILQMKNIKKLLYLSSKGQDKVPQNIYQIITNLTFGNVDQIMQLINLEVLDHLSYG
FEKISKNIKIEVCQSINNLMCSSYQAIEHILNHRYLLSKILAYIQTGNFIYKKELILAFG
NFCIHGTSSQINFMRQRGLFSILMDSFQYEDSEITLSTLEGIYRLLELGKEFQRSQQNYD
GNQVLLAFENLGLSNSLMSLQKDPNERIYEKCEQIILNFYEYQ

>TTHERM_00185260(gene)
ATGGAAACTAATGTAGAAAATAATATAGCTGATGAAATAGATGAAGCTAAGTATATTATC
AGTAAAAAGAAGGAGATATTTAGAAAGTAAATTAGAGCCAAAAAGCATAATGAATTGTTC
CATAAAAAGAGATTTGAGCTTTTAAATTAGGACAAATCTTCTAGCAAAGAACCTATTGAT
TAAATGATGTCTACTGAAAATGCTATGCCTTCAGTATTATAAGAAATTATAATTAACCAA
AAGGTAAATATTTTATAAATAAAAGATGAATTTTCATATATCTTTTGAGCAATTTTAAAT
AAACTTGAAAAGCAACAAAAAAATTTATTAAGCCATAGATAAAGAGTAGAATTAATAATT
AAGATGTTTTTTATGCATTAGGATTGATATCTAATTGTTTTATATGATATTAACTCATCC
CATTTAAAGGTTTTATTTAGAACTTAAATCCTTTCAAGTTAAAAGCAAATAAAATATTCA
CTTGAACAGCATACTTACTTACTTAGTAGTTTTTTAGTAAGATATTTTATTTACATCTTA
TTAATAAAGCCTTTTTTAGTACTTTTATTAGAATTGCATTTAATTCAATAAATAAATAAT
TAATATGATTTTCAATAAAAGAACATTCTCTAAACAAAAATATTTATTTTATAATATGAA
GTTTTTAAGTAGAACAAATAAGCAAGTATTTATTTATTTTACCATAAAGTTGATATAAAT
AAATAAATGGAATAAAAAGAAATAATATGAAAGATTTTTAAATGTATTTTAATTTTTATA
TAAATCATTATTTTTTGTTAAAAAAGCATCTTTAAGATTACTTAGATAAGATTTGCGGTG
ACATTAAGAGTTAATATTTGAGGAACGAAGTGGATAGTCCTGATTTGGCAAAAAATATTA
AAATATTAAAACTCTACACATCTAAAATTGATGAATATCCTCATATTGCTACTTGTGTGC
TGGATAATAAAATTATTTAAACTTTGCAATAAATCTTAACAGTTCCTTCACTAAATATAA
AAAATCTATAACTAGACACAGCTTAGATAATTTCTAACCTTACTTATTCAGATGCTGACA
ACATAGAAAAAATATTAGAAAATAATTTATCTTTAATTGATATTCTAGTTCAAGTGCTAA
AAGACTAAGACAACCAATACTCAACTCATGTAAAAAAATAATTAAATAAACTAAAATCTT
GATTAATTTATAATTGTTTTTTTAAATGAGAAAATAAATTTTAATTTAAACTTAAAAATA
GGCAATATATTGTTTAGCCAATATGTCTTAAGAATATTTAGATGTTAGAGACGAAGCACT
TAAAAGAGGAGTTTCTGAATGCATTATAGAAAAATATAAACAAAATAAAGCAAATAAAGC
TTTTGTTGAGTAATTAATTTGGTTTATTGCTATCTTTAGTGTAAGACCTCACCCCTATGA
ATTAGTAATCAATAAATTAACAAAAGCTTTTAATGAAAGAATTTTTAATTTAATTTTCTT
AATAGATAAGAGGCTTTATACCAATATTGGATGAATAACTTGGACTACAAGGCTAAAGCT
AAGAAAATATTAAATACATTACTTTTGCTTTGAAAAATTTGAGTGAAGGTGATGAAGATA
AAATATAGTAAATTTTATAAATGAAAAATATTAAAAAGCTGCTCTATTTGTCAAGCAAAG
GCTAAGATAAAGTACCTTAGAATATTTACTAGATCATAACAAACTTGACTTTTGGAAATG
TGGATTAAATTATGGTAAAATTTATTTATTTTTTTATTGTCGAATTTATTTTTTAATGGC
TTTTTAAGTAATTAATTAATTTAGAGGTTCTTGATCACTTGAGCTATGGATTTGAAAAGA
TTAGTAAAAACATAAAAATTGAAGTTTGCTAGTCGATTAATAATTTAATGTGTTCTAGCT
ACTAGGCCATAGAGCACATATTGAATCATAGATATTTACTTTCTAAAATTTTGGCATATA
TTTAAACAGGAAATTTTATTGTAAAAATATTTAAATTAAAAATTATAAATTTAGAAAGAA
TTTTTATTAGTATAAAAAAGAATTAATATTAGCGTTTGGCAACTTTTGCATACATGGAAC
ATCATCACAAATTAATTTTATGAGATAAAGAGGTCTTTTTTCAATTTTGATGGATAGCTT
TTAATATGAAGATTCAGAAATTACTCTAAGCACACTAGAAGGTATTTATAGGTTATTGGA
ACTTGGTAAAGAGTTCTAAAGAAGCTAACAAAACTATGATGGCAATCAGGTTTTATTAGC
TTTTGAAAATTTAGGCTTATCTAATAGTTTAATGAGCTTGTAAAAAGATCCAAATGAAAG
AATTTATGAAAAATGTGAGTAAATTATACTCAATTTCTACGAATACTAATGA