Identifiers and Description

Gene Model Identifier

TTHERM_01016220

Standard Name

IMA1 (IMportin Alpha 1)

Aliases

PreTt02656 | 198.m00076 | 3746.m00340

Description

IMA1 importin subunit alpha; Armadillo/beta-catenin-like repeat family protein; Karyopherin/Importin alpha family member

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• macronucleus (EXP) | GO:0031039 | Ref:18676955

Biological Process

• regulation of protein import into nucleus (IDA) | GO:0042306 | Ref:18676955

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.9%

TetraMine Data

TTHERM_01016220

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_20157.1	9.997093137033517e-262	armadillo/beta-catenin repeat family protein (527 aa)
Oxytricha	Contig20249.0.g40	4.99764318480009e-123	Armadillo/beta-catenin-like re peat
DictyBase	DDB_G0272318	6.999054974866289e-109	DDB_G0272318 on chromosome: 2 position 1278811 to 1280712
SGD	YNL189W	2.000234809436283e-103	SRP1 Karyopherin alpha homolog , forms a dimer with karyopher in beta Kap95p to mediate impo rt of nuclear proteins, binds the nuclear localization signa l of the substrate during impo rt; may also play a role in re gulation of protein degradatio n
WormBase	WBGene00002074	4.000392704867155e-81	locus:ima-3 Importin subunit alpha-3 status:Confirmed UniProt:Q19969 protein_id:CC D70435.1
Stentor Coeruleus	SteCoe_15530	4.1863939993042314e-51

General Information

No Data fetched for General Information

Associated Literature

1. Ref:18676955: Malone CD, Falkowska KA, Li AY, Galanti SE, Kanuru RC, LaMont EG, Mazzarella KC, Micev AJ, Osman MM, Piotrowski NK, Suszko JW, Timm AC, Xu MM, Liu L, Chalker DL (2008) Nucleus-specific importin alpha proteins and nucleoporins regulate protein import and nuclear division in the binucleate Tetrahymena thermophila. Eukaryotic cell 7(9):1487-99

Sequences

>TTHERM_01016220(coding)
ATGAATATTTTTAGTAACGTAGAACATTAAAATAGCCAAGACAAAGACAATGACGCCAAA
GAAAAGGCCAGAAGAATGGAAAACCATACTGTTGAGTTAAGAGAAAAGAAGCGTTTAGAT
ATTCTCAGAAAAAATAGAAATATTGACAAGTCAAATTAAGGTTCTGAATAGTCTTAATAA
GAAAGAGGTGGACTTACTCATTAATACTAAGCATTAATGAGCTTGGAGCCTGAATTCAGA
GCCAAGATCGAGTAAATTTACAAGATAACATTCAAGTTCGAGCAAATTGGAGAGTTGGTA
ATTGCTCTCAACTCCTAAGATGTTCTTTTCTAGCACCATGGATGTATTGGTCTTAGAAAG
TTGCTTTCTATTGAAGATTCTCCTCCCATTTAAATTGCCATCGACTCAAATTGTGTTCCT
CGTTTTATTGAATTCATCAAATAAAGTACTTATCCTGTTCTTCAGTTAGAAGCTTCATGG
TGTCTTACTAACATCGCTTCTGGTACCACTCACCAAACACAATCAATTATAGATAAGGGC
GCCATTCCTCTCTTCTGTAAGCTTCTCCTTTCTCCTTTCCAAGATATAGCCGAGCAAGCA
ATTTGGGCTATCGGTAACATTTCAGGTGACTGCAGCGTCTACAGAGACATGATTCTTAAA
TGTGATGGACTCAAGCCTCTTGTTAATATTTTGTTGAATACAAACGATAGAAAAACTATA
AAGCATGGATCTTGGGCACTCAGTAATCTTTGCAGAGGTCGTCCCTTACCTGATTATAAT
CTTGTTTAAGAAGCTGTAAAGCCACTTTGCAAGGTCCTTACGCAAGAAACTGACTCTGAA
GTCCTCACTGATTCTTCATGGGCAATTAGTTACTTGAGTGATGGTGATGAAGATAGAATT
CAACGTATCATTGATACTGGCGTCATTCCTACTTTAATAAGATTAATTAATCACTAATAC
CTTTCTGTATTAATTCCTTGTTTGCGTACTCTTGGTAACGTCTGCACTGGTACTGATGAA
TAAACTGAAGAAGTTCTTAAATATAATGCCCTCCCAGAAATATTTAAGCTTGTTAAGCAC
CAAAAGAAGGCTGTTCGTAGAGAAGCTTGTTGGGTACTTAGTAATATCGCAGCTGGTAAC
GAAAGATAAATTTCATAGATAGTTAATCAACCTTAATATGTTTAATGGCTTTTTGAATGC
ATGATCTAAGATTCTGATGAAATTGCCCGTGAAGCTACTTGGGTCATTTCTAATTGCACT
TCTCAAGCTAATCCCTAAGACATTCGTAAACTTGTAGAAATGAATGTATTAAAGATATAT
ACTGACATTCTTAAATCTACAAAGGACGTTAAAACAATAGCTGTTATTTTAGAATCATTA
AAACACATTCTCGAATGTGGTAAAAATAACTTTATGTAAGGCAACGATAACCCTTTCTGC
ATTCAATTAGAGTAATTCGGTGCTTTAGACTTTATTGAAGAACTTTAAAGACATCCTGAT
GATGATGTTTATAGAAGATCTCTCGCTATCCTTGAAAATTACTTTGATTTAGAAGATGAA
TAAGTTATTAGACCTGAATGA

>TTHERM_01016220(protein)
MNIFSNVEHQNSQDKDNDAKEKARRMENHTVELREKKRLDILRKNRNIDKSNQGSEQSQQ
ERGGLTHQYQALMSLEPEFRAKIEQIYKITFKFEQIGELVIALNSQDVLFQHHGCIGLRK
LLSIEDSPPIQIAIDSNCVPRFIEFIKQSTYPVLQLEASWCLTNIASGTTHQTQSIIDKG
AIPLFCKLLLSPFQDIAEQAIWAIGNISGDCSVYRDMILKCDGLKPLVNILLNTNDRKTI
KHGSWALSNLCRGRPLPDYNLVQEAVKPLCKVLTQETDSEVLTDSSWAISYLSDGDEDRI
QRIIDTGVIPTLIRLINHQYLSVLIPCLRTLGNVCTGTDEQTEEVLKYNALPEIFKLVKH
QKKAVRREACWVLSNIAAGNERQISQIVNQPQYVQWLFECMIQDSDEIAREATWVISNCT
SQANPQDIRKLVEMNVLKIYTDILKSTKDVKTIAVILESLKHILECGKNNFMQGNDNPFC
IQLEQFGALDFIEELQRHPDDDVYRRSLAILENYFDLEDEQVIRPE

>TTHERM_01016220(gene)
ATGAATATTTTTAGTAACGTAGAACATTAAAATAGCCAAGACAAAGACAATGACGCCAAA
GAAAAGGCCAGAAGAATGGAAAACCATACTGTTGAGTTAAGAGAAAAGAAGCGTTTAGAT
ATTCTCAGAAAAAATAGAAATATTGACAAGTCAAATTAAGGTTCTGAATAGTCTTAATAA
GAAAGAGGTGGACTTACTCATTAATACTAAGCATTAATGAGCTTGGAGCCTGAATTCAGA
GCCAAGATCGAGTAAATTTACAAGATAACATTCAAGTTCGAGCAAATTGGAGAGTTGGTA
ATTGCTCTCAACTCCTAAGATGTTCTTTTCTAGCACCATGGATGTATTGGTCTTAGAAAG
TTGCTTTCTATTGAAGATTCTCCTCCCATTTAAATTGCCATCGACTCAAATTGTGTTCCT
CGTTTTATTGAATTCATCAAATAAAGTACTTATCCTGTTCTTCAGTTAGAAGCTTCATGG
TGTCTTACTAACATCGCTTCTGGTACCACTCACCAAACACAATCAATTATAGTAATTTTA
TTTGCTTAAAACTAAAAGATACTACAAACAATCTTAAAAGTTTATAAACAAAACTTTTAC
TTCAATAATATGGGATTTTAAAGAATATTTAAAAGAATTCTATTTTATTTCACTATATTT
TAATAGATAAAAGAAGATTTTACTCGAAATTTATGCTTTTGTAGTTTTTAGCATTAAAAA
ATAGTTGTTTTATTAATCAAATTAATATTTTTTTAAATTTATAAAGGATAAGGGCGCCAT
TCCTCTCTTCTGTAAGCTTCTCCTTTCTCCTTTCCAAGATATAGCCGAGCAAGCAATTTG
GGCTATCGGTAACATTTCAGGGTAAGAATTTTGAATTGATTATTAGCAGATAAATTTTAA
AACTCAAAATAAAAAATTTTTAAGATCTTCAAAAATTTTGTTTGAATAGCAATTAATTAA
TATTAATTTATCTTGATCTTCTAAACAAAAAAGTTCGCGCAATAATTTATTAAATAATAT
AAATTTCATTACAAAAATATCCTAAGTAAAAATATTTGACTTTGATATATTAGCTTAAAA
GGAAAAAATAAATTATAATATAAAAAGGAGGAGGAAATTTCCTTTAAAAGTAAAAACGAT
TGAGCTATTTATTTATTTATTTGATCAAATAATTTATTTACGAAAGCATTTCTTAGCATC
CACTTTCTTATTTTAATTTTATTTAGAACGCGCCTATTAATAGTGAGTAATATAGACAAT
TTTTAGAGGACTCTCTATTATTTTTTCAAGCAATTTTTCGACTTAAGTTATTAATTTATT
TATAAGCTTAAAAAGACTTACAATTTTTCTAGATAGTTAGAGAGAGATATATATATAGAT
AAATATAAATATAAATAAATAAATTGCGAATTCTAATAAAATTTAAATTTAAAAATTTAA
ATTCATAAATGAATTGAAAATAATTTTAATTAATTGAATTTTTCAATTTTTTTCATCTTT
TAAAATTGTTTTTATTTTAAATAGTGACTGCAGCGTCTACAGAGACATGATTCTTAAATG
TGATGGACTCAAGCCTCTTGTTAATATTTTGTTGAATACAAACGATAGAAAAACTATAAA
GCATGGATCTTGGGCACTCAGTAATCTTTGCAGAGGTCGTCCCTTACCTGATTATAATCT
TGTTTAAGAAGCTGTAAAGCCACTTTGCAAGGTCCTTACGCAAGAAACTGACTCTGAAGT
CCTCACTGATTCTTCATGGGCAATTAGTTACTTGAGTGATGGTGATGAAGATAGAATTCA
ACGTATCATTGATACTGGCGTCATTCCTACTTTAATAAGATTAATTAATCACTAATACCT
TTCTGTATTAATTCCTTGTTTGCGTACTCTTGGTAACGTCTGCACTGGTACTGATGAATA
AACTGAAGAAGTTCTTAAATATAATGCCCTCCCAGAAATATTTAAGCTTGTTAAGCACCA
AAAGAAGGCTGTTCGTAGAGAAGCTTGTTGGGTACTTAGTAATATCGCAGCTGGTAACGA
AAGATAAATTTCATAGATAGTTAATCAACCTTAATATGTTTAATGGCTTTTTGAATGCAT
GATCTAAGATTCTGATGAAATTGCCCGTGAAGCTACTTGGGTCATTTCTAATTGCACTTC
TCAAGCTAATCCCTAAGACATTCGTAAACTTGTAGAAATGAATGTATTAAAGATATATAC
TGACATTCTTAAATCTACAAAGGACGTTAAAACAATAGCTGTTATTTTAGAATCATTAAA
ACACATTCTCGAATGTGGTAAAAATAACTTTATGTAAGGCAACGATAACCCTTTCTGCAT
TCAATTAGAGTAATTCGGTGCTTTAGACTTTATTGAAGAACTTTAAAGACATCCTGATGA
TGATGTTTATAGAAGATCTCTCGCTATCCTTGAAAATTACTTTGATTTAGAAGATGAATA
AGTTATTAGACCTGAATGA