Identifiers and Description

Gene Model Identifier

TTHERM_00558350

Standard Name

IGR1 (Induced during Granule Regeneration)

Aliases

PreTt07932 | 73.m00176 | 3735.m00070

Description

IGR1 hypothetical protein; Dense core granule (DCG) protein; induced during DCG regeneration- function unknown; non-architectural cargo protein that localizes to and is secreted from DCGs during regulated exocytosis; not required for DCG lattice assembly

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• dense core granule (IDA) | GO:0031045 | Ref:16014006

Biological Process

• vesicle organization (IEP) | GO:0016050 | Ref:12456006

Domains

• ( PF07601 ) Protein of unknown function (DUF1562)

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: Yes
Presense Probability: 92.5%

TetraMine Data

TTHERM_00558350

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Stentor Coeruleus	SteCoe_10321	0
Tetrahymena borealis	EI9_17147.1	2.000808864924972e-124	hypothetical protein (311 aa)

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16014006: Bowman GR, Smith DG, Michael Siu KW, Pearlman RE, Turkewitz AP (2005) Genomic and proteomic evidence for a second family of dense core granule cargo proteins in Tetrahymena thermophila. The Journal of eukaryotic microbiology 52(4):291-7
2. Ref:12456006: Haddad A, Bowman GR, Turkewitz AP (2002) New class of cargo protein in Tetrahymena thermophila dense core secretory granules. Eukaryotic cell 1(4):583-93
3. Ref:11779800: Bowman GR, Turkewitz AP (2001) Analysis of a mutant exhibiting conditional sorting to dense core secretory granules in Tetrahymena thermophila. Genetics 159(4):1605-16

Sequences

>TTHERM_00558350(coding)
ATGAGAAAGATCATTCTTTTGTTAGCTATCATTAGTTTGGCACTCTGCTAAGAACTTATA
GTTGAAAAAGTAGCAGGATAATACAACTCAGGTTAAAAGTTCGCAAAATCCTGGTAAAAT
TCATAATGGAACGATTATCAAGATTTCGCTATTTATGGATGGTTTAAGATTGACTCTTCA
TACTAAATTGCTGAGTGGTCAACTGGTTTCCACTTTACTTCAAATTAGGACAAAGATTGG
ACTAACGCCTCTGCTCCTGGTGATAGAGTATTGGCATTCTGGGTTATTGGAAATACTCTC
CACAATCCTACTTACTCTTTAGCAAGAGGTAATACTAATTATTACGAAAATCTTTCCTTC
GCTGCTGGAGATACTAATAAATGGGCTTTTATTTATGTTACACATGGTTCTAGCTAATAA
GCATAATACGTCTATTACTTACTTCCTTCCTCTGGTGTTGTAACCAAGAAAATAGCTTCA
ATCACTCATAAAACTTCCACCTTCTATCAAATCAATGTTGGTTAATCATTCAGCTTCAAA
TATTTCCCTGGTTCTTTTTGGAGACTCTCACTTATTGCTGGACCTAATGCTTACAGAGAA
AGTGGTTTTGAATAGTTCTAAAACATATAACCTGACGTTGTTCCTAGCTGTCCTATTCTT
TTCACTGGATGTAACTATAGTGGTAAGGGTGATTCTTTATGCTAAAGCTCTCCTTCTTAT
AACGTTACTGCTGTTCACTCAATCTACCTCCCTGCTAACTTCACTGCTACTTTACATGAT
CAAGCTAATTACGCAGGAAAGAAGATCGTTTATTCCCAAAGTATTGAATGTATTACCTAA
TTAAATTGGGCTTACTTACTCTCTACTCATGCCATTACTATTGAGGATGAAACTAAAACT
GTTCTCAGAAGAAACAACAGAAGAAATTGA

>TTHERM_00558350(protein)
MRKIILLLAIISLALCQELIVEKVAGQYNSGQKFAKSWQNSQWNDYQDFAIYGWFKIDSS
YQIAEWSTGFHFTSNQDKDWTNASAPGDRVLAFWVIGNTLHNPTYSLARGNTNYYENLSF
AAGDTNKWAFIYVTHGSSQQAQYVYYLLPSSGVVTKKIASITHKTSTFYQINVGQSFSFK
YFPGSFWRLSLIAGPNAYRESGFEQFQNIQPDVVPSCPILFTGCNYSGKGDSLCQSSPSY
NVTAVHSIYLPANFTATLHDQANYAGKKIVYSQSIECITQLNWAYLLSTHAITIEDETKT
VLRRNNRRN

>TTHERM_00558350(gene)
ATGAGAAAGATCATTCTTTTGTTAGCTATCATTAGTTTGGCACTCTGCTAAGAACTTATA
GTTGAAAAAGTAGCAGGATAATACAACTCAGGTTAAAAGTTCGCAAAATCCTGGTAAAAT
TCATAATGGAACGATTATCAAGATTTCGCTATTTATGGATGGTTTAAGATTGACTCTTCA
TACTAAATTGCTGAGTGGTCAACTGGTTTCCACTTTACTTCAAATTAGGACAAAGATTGG
ACTAACGCCTCTGCTCCTGGTGATAGAGTATTGGCATTCTGGGTTATTGGAAATACTCTC
CACAATCCTACTTACTCTTTAGCAAGAGGTAATACTAATTATTACGAAAATCTTTCCTTC
GCTGCTGGAGATACTAATAAATGGGCTTTTATTTATGTTACACATGGTTCTAGCTAATAA
GCATAATACGTCTATTACTTACTTCCTTCCTCTGGTGTTGTAACCAAGAAAATAGCTTCA
ATCACTCATAAAACTTCCACCTTCTATCAAATCAATGTTGGTTAATCATTCAGCTTCAAA
TATTTCCCTGGTTCTTTTTGGAGACTCTCACTTATTGCTGGACCTAATGCTTACAGAGAA
AGTGGTTTTGAATAGTTCTAAAACATATAACCTGACGTTGTTCCTAGCTGTCCTATTCTT
TTCACTGGATGTAACTATAGTGGTAAGGGTGATTCTTTATGCTAAAGCTCTCCTTCTTAT
AACGTTACTGCTGTTCACTCAATCTACCTCCCTGCTAACTTCACTGCTACTTTACATGAT
CAAGCTAATTACGCAGGAAAGAAGATCGTTTATTCCCAAAGTATTGAATGTATTACCTAA
TTAAATTGGGCTTACTTACTCTCTACTCATGCCATTACTATTGAGGATGAAACTAAAACT
GTTCTCAGAAGAAACAACAGAAGAAATTGA