Identifiers and Description

Gene Model Identifier

TTHERM_01141570

Standard Name

ICL1 (IsoCitrate Lyase 1)

Aliases

PreTt20062 | 251.m00042 | 3821.m00564

Description

ICL1 isocitrate lyase; Isocitrate lyase family protein; similar domain structure to yeast isocitrate lyase 1 (ICL1)

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• catalytic activity (IEA) | GO:0003824

Biological Process

• metabolic process (IEA) | GO:0008152

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.6%

TetraMine Data

TTHERM_01141570

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_20883.1	9.997093137033517e-262	hypothetical protein (504 aa)
Oxytricha	Contig20680.0.g93	9.997093137033517e-262	Isocitrate lyase family
SGD	YER065C	2.0007442334946695e-153	ICL1 Isocitrate lyase, catalyz es the formation of succinate and glyoxylate from isocitrate , a key reaction of the glyoxy late cycle; expression of ICL1 is induced by growth on ethan ol and repressed by growth on glucose
WormBase	WBGene00001564	2.998830401637127e-79	locus:icl-1 status:Confirmed UniProt:Q8IA71 protein_id :CCD63239.1
DictyBase	DDB_G0273017	5.998439611888618e-47	DDB_G0273017 on chromosome: 2 position 2236569 to 2237975

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_01141570(coding)
ATGGACGTTGAAGGAAAGAGACTCTAAGAAATCACTGCTGAAATCCAAAAATGGTGGACT
AACTCTCGTTGGGAAAATGTTGAAAGACCCTACTAAGCTTAAGATGTTGCCCGTTTAAGA
CCCACCATCCCCATGGACTACCCCTCCAACTACTAATCCAAGAAGATGTGGAAACTCTTG
AAGGAAGCCCAAGCCAACAAGGGATTCCACCACACTTTCGGTGCCTTAGACCCCGTTCAA
GTTATCAACTTATCCAAGTACTTGAGAACTGTCTACGTCTCTGGATGGTAATGCTCTGCC
ACTGCCTCCACTACTAATGAACCTGGTCCAGATTTTGCTGATTACCCTGCCAACACTGTC
CCCAACAAAGTTGACCAACTCTTCAAGGCTTAACTTTTACAAGACAGAATCCAAAATGAA
CAAAGAGCTCATTTGACCCCTGAATAAAGAGCTAAGACTCCCAGAGTTGACTACCTTGCT
CCTATGATTGCTGATGCTGATGCTGGTTTCGGTGGTATTACTTCAACCATGAAGTTAATT
AAGTTATTCATTGAAGCTGGTGCTGCTGGTATCCATCTTGAAGATTAAAGACCTGGTACC
AAGAAATGTGGTCACATGAGTGGTAAGGTCGTTGTCTCCACTCGCGAACACGTCAACAGA
TTAATTGCTTGCAGACTCCAAGCTGATATTATGGGAACTGATTTAATTATCCTCGCCAGA
ACTGATGCTTTATCTGCTAGACTTATTGACTCCAACTGTGACCCCGTTGACCACCCCTTC
ATCCTTGGTCTTTGCCCTGATGGTAAGGAAAGAACTTTCCCTAATGCAGGTCTTGAAGCT
ATCAAGGCTAAGTTCACTGGTGCTAAGGTCCAAGAAGTCACCAAGCTCTGGCTCTCTAAG
TGTTACGATCTTTCCCTCACTCAAGCCCACGAATACGCTAGAACTCTCGGTTTTGACTTC
CAATTCGACTGGGAAGCTCTCCGTTCATCTGAAGGTTTCTACTCCATTGACGGTTGTGTT
GAATTATGTGCTGCTCGTGCTAAGTAATATTTAAGATATGCTGATATGGTTTGGATGGAA
ACTCCTACTCCCTCTTTGGAAGTTGCTACTAAGTTCTCTACCTTGGTAAAGAATAACCAT
CCCACCAAATTATTGGCTTACAACCTTTCCCCCTCTTTCAACTGGTCTGCTTTCAACATG
TCCAATGCTCAAATCCAATCTTTCTGTGCTGACCTTGGTAGACTCGGATACACCTGGTAA
TTCATTACTTTAGCTGGTTTCCACTTGAATGCTCTCAAGTCTGAAAAGCTCTCTAAGGAT
CTTGCTGCCCGTGGTATGCTCGCCTACGTCGAAACTGTCCAAAGAAAGGAAGAAAAGCAC
AAAGTCGACCAACTCACCCACCAAAAATGGTCTGGTGCTAACTACGTTGATGCTTGCCAA
GCCCTTGTTCAACCCGAATCTCAAACCTTAGCCTCCTCCAAAGACTCTACTGAAAACTAA
TTCAAGCATTGA

>TTHERM_01141570(protein)
MDVEGKRLQEITAEIQKWWTNSRWENVERPYQAQDVARLRPTIPMDYPSNYQSKKMWKLL
KEAQANKGFHHTFGALDPVQVINLSKYLRTVYVSGWQCSATASTTNEPGPDFADYPANTV
PNKVDQLFKAQLLQDRIQNEQRAHLTPEQRAKTPRVDYLAPMIADADAGFGGITSTMKLI
KLFIEAGAAGIHLEDQRPGTKKCGHMSGKVVVSTREHVNRLIACRLQADIMGTDLIILAR
TDALSARLIDSNCDPVDHPFILGLCPDGKERTFPNAGLEAIKAKFTGAKVQEVTKLWLSK
CYDLSLTQAHEYARTLGFDFQFDWEALRSSEGFYSIDGCVELCAARAKQYLRYADMVWME
TPTPSLEVATKFSTLVKNNHPTKLLAYNLSPSFNWSAFNMSNAQIQSFCADLGRLGYTWQ
FITLAGFHLNALKSEKLSKDLAARGMLAYVETVQRKEEKHKVDQLTHQKWSGANYVDACQ
ALVQPESQTLASSKDSTENQFKH

>TTHERM_01141570(gene)
ATGGACGTTGAAGGAAAGAGACTCTAAGAAATCACTGCTGAAATCCAAAAATGGTGGACT
AACTCTCGTTGGGAAAATGTTGAAAGACCCTACTAAGCTTAAGATGTTGCCCGTTTAAGA
CCCACCATCCCCATGGACTACCCCTCCAACTACTAATCCAAGAAGATGTGGAAACTCTTG
AAGGAAGCCCAAGCCAACAAGGGATTCCACCACACTTTCGGTGCCTTAGACCCCGTTCAA
GTTATCAACTTATCCAAGTACTTGAGAACTGTCTACGTCTCTGGATGGTAATGCTCTGCC
ACTGCCTCCACTACTAATGAACCTGGTCCAGATTTTGCTGATTACCCTGCCAACACTGTC
CCCAACAAAGTTGACCAACTCTTCAAGGCTTAACTTTTACAAGACAGAATCCAAAATGAA
CAAAGAGCTCATTTGACCCCTGAATAAAGAGCTAAGACTCCCAGAGTTGACTACCTTGCT
CCTATGATTGCTGATGCTGATGCTGGTTTCGGTGGTATTACTTCAACCATGAAGTTAATT
AAGTTATTCATTGAAGCTGGTGCTGCTGGTATCCATCTTGAAGATTAAAGACCTGGTACC
AAGAAATGTGGTCACATGAGTGGTAAGGTCGTTGTCTCCACTCGCGAACACGTCAACAGA
TTAATTGCTTGCAGACTCCAAGCTGATATTATGGGAACTGATTTAATTATCCTCGCCAGA
ACTGATGCTTTATCTGCTAGACTTATTGACTCCAACTGTGACCCCGTTGACCACCCCTTC
ATCCTTGGTCTTTGCCCTGATGGTAAGGAAAGAACTTTCCCTAATGCAGGTCTTGAAGCT
ATCAAGGCTAAGTTCACTGGTGCTAAGGTCCAAGAAGTCACCAAGCTCTGGCTCTCTAAG
TGTTACGATCTTTCCCTCACTCAAGCCCACGAATACGCTAGAACTCTCGGTTTTGACTTC
CAATTCGACTGGGAAGCTCTCCGTTCATCTGAAGGTTTCTACTCCATTGACGGTTGTGTT
GAATTATGTGCTGCTCGTGCTAAGTAATATTTAAGATATGCTGATATGGTTTGGATGGAA
ACTCCTACTCCCTCTTTGGAAGTTGCTACTAAGTTCTCTACCTTGGTAAAGAATAACCAT
CCCACCAAATTATTGGCTTACAACCTTTCCCCCTCTTTCAACTGGTCTGCTTTCAACATG
TCCAATGCTCAAATCCAATCTTTCTGTGCTGACCTTGGTAGACTCGGATACACCTGGTAA
TTCATTACTTTAGCTGGTTTCCACTTGAATGCTCTCAAGTCTGAAAAGCTCTCTAAGGAT
CTTGCTGCCCGTGGTATGCTCGCCTACGTCGAAACTGTCCAAAGAAAGGAAGAAAAGCAC
AAAGTCGACCAACTCACCCACCAAAAGTAATTATAAAAACATTTTTATCTATATAAAATA
AAAAAAAATGGCTCTGATAAGTAGGTATAAATAAAATATTCAAATAATAGAGATAGACAA
TCATATGATCTTTTAATAGCAATTTATCAATGTTTAATATATCAAAAAAAGCAATAGAAC
AAACAAAAGCATTCATTCGATCTATTAAAAAATAAAAAGAATATTTTATTTATACACCTC
TATAATAAATTGCTAATTTTATTTACTCATTCATTTATTAAAATTAATTTGTATTAAATA
GATGGTCTGGTGCTAACTACGTTGATGCTTGCCAAGCCCTTGTTCAACCCGAATCTCAAA
CCTTAGCCTCCTCCAAAGACTCTACTGAAAACTAATTCAAGCATTGA