Identifiers and Description

Gene Model Identifier

TTHERM_01044390

Standard Name

HSP71 (Heat Shock Protein )

Aliases

PreTt05899 | 209.m00036 | 3760.m00226 | HSP70b

Description

Putative 70-kDa heat-shock protein (hsp70); two forms of hsp70 associate with tubulin, mitochondrial hsp70 associates with 14-nm filament protein (14FP), hsp70 proteins have evolutionarily conserved roles in folding nascent polypeptides

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

No Data fetched for Domains

Gene Expression Profile

  • Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 13%

TetraMine Data

TTHERM_01044390

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

SourceIdentifierScoreDescription
Stentor CoeruleusSteCoe_9940
WormBaseWBGene000020059.997093137033517e-262locus:hsp-1 Heat shock 70 kD
a protein A status:Confirmed
UniProt:P09446 protein_id
:CAB02319.1
Tetrahymena borealisEI9_18058.19.997093137033517e-262dnaK protein (645 aa)
DictyBaseDDB_G02691449.997093137033517e-262hspB on chromosome: 1 position
4410084 to 4412006
OxytrichaContig18685.0.g309.997093137033517e-262Hsp70 protein
SGDYBL075C9.997093137033517e-262SSA3 ATPase involved in protei
n folding and the response to
stress; plays a role in SRP-de
pendent cotranslational protei
n-membrane targeting and trans
location; member of the heat s
hock protein 70 (HSP70) family
; localized to the cytoplasm

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:25586926: Fukuda Y, Akematsu T, Attiq R, Tada C, Nakai Y, Pearlman RE (2015) Role of the Cytosolic Heat Shock Protein 70 Ssa5 in the Ciliate Protozoan Tetrahymena thermophila. The Journal of eukaryotic microbiology 62(4):481-93
  2. Ref:18055912: Barchetta S, La Terza A, Ballarini P, Pucciarelli S, Miceli C (2008) Combination of two regulatory elements in the Tetrahymena thermophila HSP70-1 gene controls heat shock activation. Eukaryotic cell 7(2):379-86
  3. Ref:17959197: Smith DG, Gawryluk RM, Spencer DF, Pearlman RE, Siu KW, Gray MW (2007) Exploring the mitochondrial proteome of the ciliate protozoon Tetrahymena thermophila: direct analysis by tandem mass spectrometry. Journal of molecular biology 374(3):837-63
  4. Ref:17189490: Xie R, Clark KM, Gorovsky MA (2007) Endoplasmic reticulum retention signal-dependent glycylation of the Hsp70/Grp170-related Pgp1p in Tetrahymena. Eukaryotic cell 6(3):388-97
  5. Ref:11260259: Takeda T, Yoshihama I, Numata O (2001) Identification of Tetrahymena hsp60 as a 14-nm filament protein/citrate synthase-binding protein and its possible involvement in the oral apparatus formation. Genes to cells : devoted to molecular & cellular mechanisms 6(2):139-49
  6. Ref:9247200: Williams NE, Nelsen EM (1997) HSP70 and HSP90 homologs are associated with tubulin in hetero-oligomeric complexes, cilia and the cortex of Tetrahymena. Journal of cell science 110 ( Pt 14)( ):1665-72
  7. Ref:8102520: Hendrick JP and Hartl FU (1993) Molecular chaperone functions of heat-shock proteins. Annu Rev Biochem 62:349-84
  8. Ref:8102139: Soares H, Galego L, Cóias R, Rodrigues-Pousada C (1993) The mechanisms of tubulin messenger regulation during Tetrahymena pyriformis reciliation. The Journal of biological chemistry 268(22):16623-30
  9. Ref:8357830: Amaral MD, Galego L, Rodrigues-Pousada C (1993) Heat-shock-induced protein synthesis is responsible for the switch-off of hsp70 transcription in Tetrahymena. Biochimica et biophysica acta 1174(2):133-42
  10. Ref:2663194: Martindale DW, Gu ZM, Csank C (1989) Isolation and complete sequence of the yeast isoleucyl-tRNA synthetase gene (ILS1). Current genetics 15(2):99-106

Sequences

>TTHERM_01044390(coding)
ATGGGTAAAAACGATAAAACTAAAGGAGTAGGTATTGGTATCGATCTTGGTACTACTTAT
TCTTGTGTTGGAGTTTTCTAAAATGATAGAGTTGAAATCATTTGTAATGATCAAGGAAAC
AGAACTACACCTTCTTATGTTGCTTTCACAGAAACTGAGAGACTTCTTGGTGATTCAGCA
AAATGCTAAGCTGCAAGAAACCCCACAAATACAGTCTTTGATGCTAAAAGATTAATTGGA
AGAAAGTTTAGTGATACCTCAGTTCAACAAGATATGAAATATTGGCCATTTAAGGTATAG
CCAGGACCTGATGATAAACCTTTAATTGCTGTGCAATTCAAAAACGAAACTAAATAATTT
CATGCTGAGGAGATATCATCTATGGTTTTAAGTAAGATGAAAGATATTGCTGAATCATAT
CTTTCAAAACCAGTTAAAAATGCTGTTATTACAGTCCCAGCTTACTTTAATGACCCTTAA
AGATAAGCAACAAAAGATGCTGGTACTATTGCAGGATTGAATGTACTTCGTATTATTAAT
GAACCAACTGCTGCTGCCATGGCTTATGGTTTAGACTAAAAATTGCAAGGAGAAAAAAAT
ATTCTTGTTTTTGATTTAGGTGGTGGTACTTTTGATGTCTCTCTATTAACAATAGATGGT
GGTTTCTTTGAAGTAAGAGCAACCGCAGGAGACACTCACCTTGGTGGAGAAGATTTTGAC
AACAAATTAGTTGAATACTGTTCTAATGAATTTAAAAAAAAGACTGGTATAGATATTAGA
AGAAATCCTCGTGCTATGAGAAGACTAAGGACTTAATGTGAGAGAGCTAAAAGAATTCTT
TCTTCGAGCGCAATGGCTTCTATTGAAGTTGATGCACTAGCAGAGAATGAAGATTTAAAT
ATGATTATCTCAAGGCCAAAATTTGAAGAATTATGCCTGAGCTTATTCTAGCAATGTATT
CCTCCTGTTGAAAAAGTCCTTTAAGATGCAAAAATGTCTAAAAGTTAAATAGATGAAATT
GTTCTCGTTGGAGGTTCGAGCCGTATTCCTAAAGTCATCTAGTTAGTCACAGAATTTTTT
AATGGTAAAGAACCAAATAGATCAATTAATCCTGATGAAGCAGTTGCATATGGAGCAGCA
GTTTAGGCTGCAATTCTAACAGATAATGGAGGAACTTCTACTGAAGGCTTAATCCTTCTT
GATATTACTCCTTTATCATTGGGTATAGAAACATCAGGTTAAGTCATGACTACTTTGATC
CCAAGAGGTACAACCATTCCTACTCAAAAATCTTAAATATTTACAACATTTGCTGATAAC
TAGAGGGCTGTTTCAATTTAAGTCTTCTAAGGTGAAAGATAGTTCACAAAAGATAATCAC
TTGCTTGGTAAATTTAATTTAGAAGGAATCTCTCCAGCACCTAGAGGTATTCCTAAGATA
GAAGTAGCTTTTGATATTGATAATAATGGTATCTTAAATGTGAGTGCTAAAGACCTTGCA
ACAAATATTGTTGAAAAAATAATCGTGACAAACTAGCAAACAAGATTTTCAGATAGTGAA
ATCTAGAACTTAATTAAAGAGTCTGAAAAGTATAAAGCTGAAGATGAAGCTATTAAGAAG
AAGCTAGATGCTAAAAACAATCTTGAAAGCTATGTATTTTCAATTCGAAATACCTTGAAT
GATTAAAAACTAAAAGACAAGATCAATAAAGAAGAAAGATAAAACCTTGAATAATTGATC
GACTAAACATTTTAATGGATAGAATCAAACTAAAATGTAGAAGCAGAATTTTACAAGCAA
AAACAGACAAATCTTGAAGAATCTTTTAACCCGATAATGATGAGAATTTATGGACAAAAT
GGATAAAGTGCTCCTTATAATTCTGGTAAAGAGCCCTCATCTACTTTCTCTGCAGATGAA
GTTGATTGA


>TTHERM_01044390(protein)
MGKNDKTKGVGIGIDLGTTYSCVGVFQNDRVEIICNDQGNRTTPSYVAFTETERLLGDSA
KCQAARNPTNTVFDAKRLIGRKFSDTSVQQDMKYWPFKVQPGPDDKPLIAVQFKNETKQF
HAEEISSMVLSKMKDIAESYLSKPVKNAVITVPAYFNDPQRQATKDAGTIAGLNVLRIIN
EPTAAAMAYGLDQKLQGEKNILVFDLGGGTFDVSLLTIDGGFFEVRATAGDTHLGGEDFD
NKLVEYCSNEFKKKTGIDIRRNPRAMRRLRTQCERAKRILSSSAMASIEVDALAENEDLN
MIISRPKFEELCLSLFQQCIPPVEKVLQDAKMSKSQIDEIVLVGGSSRIPKVIQLVTEFF
NGKEPNRSINPDEAVAYGAAVQAAILTDNGGTSTEGLILLDITPLSLGIETSGQVMTTLI
PRGTTIPTQKSQIFTTFADNQRAVSIQVFQGERQFTKDNHLLGKFNLEGISPAPRGIPKI
EVAFDIDNNGILNVSAKDLATNIVEKIIVTNQQTRFSDSEIQNLIKESEKYKAEDEAIKK
KLDAKNNLESYVFSIRNTLNDQKLKDKINKEERQNLEQLIDQTFQWIESNQNVEAEFYKQ
KQTNLEESFNPIMMRIYGQNGQSAPYNSGKEPSSTFSADEVD


>TTHERM_01044390(gene)
ATGGGTAAAAACGATAAAACTAAAGGAGTAGGTATTGGTATCGATCTTGGTACTACTTAT
TCTTGTGTTGGAGTTTTCTAAAATGATAGAGTTGAAATCATTTGTAATGATCAAGGAAAC
AGAACTACACCTTCTTATGTTGCTTTCACAGAAACTGAGAGACTTCTTGGTGATTCAGCA
AAATGCTAAGCTGCAAGAAACCCCACAAATACAGTCTTTGATGCTAAAAGATTAATTGGA
AGAAAGTTTAGTGATACCTCAGTTCAACAAGATATGAAATATTGGCCATTTAAGGTATAG
CCAGGACCTGATGATAAACCTTTAATTGCTGTGCAATTCAAAAACGAAACTAAATAATTT
CATGCTGAGGAGATATCATCTATGGTTTTAAGTAAGATGAAAGATATTGCTGAATCATAT
CTTTCAAAACCAGTTAAAAATGCTGTTATTACAGTCCCAGCTTACTTTAATGACCCTTAA
AGATAAGCAACAAAAGATGCTGGTACTATTGCAGGATTGAATGTACTTCGTATTATTAAT
GAACCAACTGCTGCTGCCATGGCTTATGGTTTAGACTAAAAATTGCAAGGAGAAAAAAAT
ATTCTTGTTTTTGATTTAGGTGGTGGTACTTTTGATGTCTCTCTATTAACAATAGATGGT
GGTTTCTTTGAAGTAAGAGCAACCGCAGGAGACACTCACCTTGGTGGAGAAGATTTTGAC
AACAAATTAGTTGAATACTGTTCTAATGAATTTAAAAAAAAGACTGGTATAGATATTAGA
AGAAATCCTCGTGCTATGAGAAGACTAAGGACTTAATGTGAGAGAGCTAAAAGAATTCTT
TCTTCGAGCGCAATGGCTTCTATTGAAGTTGATGCACTAGCAGAGAATGAAGATTTAAAT
ATGATTATCTCAAGGCCAAAATTTGAAGAATTATGCCTGAGCTTATTCTAGCAATGTATT
CCTCCTGTTGAAAAAGTCCTTTAAGATGCAAAAATGTCTAAAAGTTAAATAGATGAAATT
GTTCTCGTTGGAGGTTCGAGCCGTATTCCTAAAGTCATCTAGTTAGTCACAGAATTTTTT
AATGGTAAAGAACCAAATAGATCAATTAATCCTGATGAAGCAGTTGCATATGGAGCAGCA
GTTTAGGCTGCAATTCTAACAGATAATGGAGGAACTTCTACTGAAGGCTTAATCCTTCTT
GATATTACTCCTTTATCATTGGGTATAGAAACATCAGGTTAAGTCATGACTACTTTGATC
CCAAGAGGTACAACCATTCCTACTCAAAAATCTTAAATATTTACAACATTTGCTGATAAC
TAGAGGGCTGTTTCAATTTAAGTCTTCTAAGGTGAAAGATAGTTCACAAAAGATAATCAC
TTGCTTGGTAAATTTAATTTAGAAGGAATCTCTCCAGCACCTAGAGGTATTCCTAAGATA
GAAGTAGCTTTTGATATTGATAATAATGGTATCTTAAATGTGAGTGCTAAAGACCTTGCA
ACAAATATTGTTGAAAAAATAATCGTGACAAACTAGCAAACAAGATTTTCAGATAGTGAA
ATCTAGAACTTAATTAAAGAGTCTGAAAAGTATAAAGCTGAAGATGAAGCTATTAAGAAG
AAGCTAGATGCTAAAAACAATCTTGAAAGCTATGTATTTTCAATTCGAAATACCTTGAAT
GATTAAAAACTAAAAGACAAGATCAATAAAGAAGAAAGATAAAACCTTGAATAATTGATC
GACTAAACATTTTAATGGATAGAATCAAACTAAAATGTAGAAGCAGAATTTTACAAGCAA
AAACAGACAAATCTTGAAGAATCTTTTAACCCGATAATGATGAGAATTTATGGACAAAAT
GGATAAAGTGCTCCTTATAATTCTGGTAAAGAGCCCTCATCTACTTTCTCTGCAGATGAA
GTTGATTGA