Identifiers and Description

Gene Model Identifier

TTHERM_00086760

Standard Name

GRPE1 (GRPE heat shock protein 1)

Aliases

PreTt16425 | 6.m00499 | 3836.m02092 | TGRPE1

Description

Co-chaperone GrpE family protein; expressed during growth and conjugation

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• mitochondrion (IEA) | GO:0005739

Molecular Function

• protein homodimerization activity (IEA) | GO:0042803
• adenyl-nucleotide exchange factor activity (IEA) | GO:0000774
• chaperone binding (IEA) | GO:0051087

Biological Process

• protein import into mitochondrial matrix (IEA) | GO:0030150
• protein folding (IEA) | GO:0006457

Domains

• ( PF02037 ) SAP domain
• ( PF06519 ) TolA protein
• ( TIGR02794 ) protein TolA
• ( PF01025 ) co-chaperone GrpE
• ( TIGR00165 ) ribosomal protein S18

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 15.6%

TetraMine Data

TTHERM_00086760

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_02467.1	1.0003279799459891e-139	co-chaperone GrpE family prote in (325 aa)
Oxytricha	Contig15049.0.g101	5.998760051700188e-30	GrpE
SGD	YOR232W	7.999528511121947e-28	MGE1 Mitochondrial matrix coch aperone, acts as a nucleotide release factor for Ssc1p in pr otein translocation and foldin g; also acts as cochaperone fo r Ssq1p in folding of Fe-S clu ster proteins; homolog of E. c oli GrpE
DictyBase	DDB_G0283763	2.000620012690291e-23	grpE on chromosome: 4 position 1238328 to 1239107
WormBase	WBGene00007927	2.9990241513684e-21	GrpE protein homolog, mitochon drial status:Confirmed Uni Prot:Q18421 protein_id:CAA87 101.1

General Information

No Data fetched for General Information

Associated Literature

1. Ref:SUPR000329

Sequences

>TTHERM_00086760(coding)
ATGAAATCATTCGCTACTTTAGTCATTAGAGCTGCCAAAACCCAAAACATTGTCAGTACC
GCCTTGCCCAAGAACCTCTTGTAATCAAGAGTCTGTGCCTTCACTTAGATTCCCAAAAAT
AACTTCTGGAAGAATAACGGTTAAGATAATGAAGTTAAAGACGAAGAAGTTGAAGAATTA
GAAAAGTTAACCAAGCAAAGAATGGAAAGTGAAACAGCAAAGAATTAACAATAACAAGAA
TAAGCCGAATTGAAGAAGCAAAAGGAAGCTGAAGAAAAGGCTAAGAAGTAAAAGGAAGAT
GAAGAATGGCTCAAGCAATAAGAACTTAAGGATAAGAAGAGAGAAGAAGAAGTCAGAAAG
ATTCGTGAAAAGGATGCTGAAAAGAAACTCCCCGAAAGTGTTGAATTATTGTTAAAAATG
GAAGGTGAACCTGCTAAGAAGAAAATCTTACACTTATTTGAACAACTCAAAGAAAAGGCT
TAAACTTTAGAATAAGAAAATAAGCTCCTAGCTGAATAGAAAACTGCTTATCAAACATAA
ACTACCACCTGGTAAGAAAAAGCTAAGGAATTACACAATATCACAGAAAATACTTTGAAA
GATATGGAATTGATGAGAATAAGATTAGAAAAGGAAAAAGAATAAACTAAAATCTTTGCT
ATCAGTAAGTTTGCTGGTGAAGTACTTGAAGTCAATGATAACATTGAAAGAGCCCTCAAT
GCTAATAAAGAATTAGCTGGAAAAGAAAATGGTTTGTTTGAAGGTACAATCATGACCCAA
AAAATCTTAGAACAAATCTTATAAAGAAATGGTATTGTTAAACTTAATCCTGAAGGTGAA
AAGTTTGATCCTAACTTCCATGATGCTCTCTGCCAAGTTCCTGATCCCACCAAAGAATCT
GGTAGCGTTGCCTTCGTTGCCCAAACTGGTTACAAAATTTACGATAGAGTCTTACGTCCT
GCTAAAGTTGGTGTTACTTACAAGAACTGA

>TTHERM_00086760(protein)
MKSFATLVIRAAKTQNIVSTALPKNLLQSRVCAFTQIPKNNFWKNNGQDNEVKDEEVEEL
EKLTKQRMESETAKNQQQQEQAELKKQKEAEEKAKKQKEDEEWLKQQELKDKKREEEVRK
IREKDAEKKLPESVELLLKMEGEPAKKKILHLFEQLKEKAQTLEQENKLLAEQKTAYQTQ
TTTWQEKAKELHNITENTLKDMELMRIRLEKEKEQTKIFAISKFAGEVLEVNDNIERALN
ANKELAGKENGLFEGTIMTQKILEQILQRNGIVKLNPEGEKFDPNFHDALCQVPDPTKES
GSVAFVAQTGYKIYDRVLRPAKVGVTYKN

>TTHERM_00086760(gene)
ATGAAATCATTCGCTACTTTAGTCATTAGAGCTGCCAAAACCCAAAACATTGTCAGTACC
GCCTTGCCCAAGAACCTCTTGTAATCAAGAGTCTGTGCCTTCACTTAGATTCCCAAAAAT
AAGTAATTTTTCTCTTCTTTTATTCCATACCATTTAAAAAACTGAAGAAATCTCCCTTCT
AATCAAACTTAGGGTTCATACATTTATTCATTTAAGACTCTTTTTTTAACAGATATATTT
TTAAATAATATTTTACAATAATTATTTTATAATAATAAAGCTTCTGGAAGAATAACGGTT
AAGATAATGAAGTTAAAGACGAAGAAGTTGAAGAATTAGAAAAGTTAACCAAGCAAAGAA
TGGAAAGTGAAACAGCAAAGAATTAACAATAACAAGAATAAGCCGAATTGAAGAAGCAAA
AGGAAGCTGAAGAAAAGGCTAAGAAGTAAAAGGAAGATGAAGAATGGCTCAAGCAATAAG
AACTTAAGGATAAGAAGAGAGAAGAAGAAGTCAGAAAGATTCGTGAAAAGGATGCTGAAA
AGAAACTCCCCGAAAGTGTTGAATTATTGTTAAGTAATCCTTAAATTTTTTACTTTACAA
CTTAGATTCATGATATACAAACAATATGATACATTTATTAGCTCATAATTTTGTTATATT
CAATCAAATTTTAGCGTTTTTATTAATAATTTGTTTTAACTAAAAGAAATGGAAGGTGAA
CCTGCTAAGAAGAAAATCTTACACTTATTTGAACAACTCAAAGAAAAGGCTTAAACTTTA
GAATAAGAAAATAAGCTCCTAGCTGAATAGGTAAAATCCTCAACAATAATTAACTTATGT
TTATTTATAATGCTTTAAAAATATAAATAGAAAACTGCTTATCAAACATAAACTACCACC
TGGTAAGAAAAAGCTAAGGAATTACACAATATCACAGAAAATACTTTGAAAGATATGGAA
TTGATGAGAATAAGATTAGAAAAGGAAAAAGAATAAACTAAAATCTTTGCTATCAGTAAG
TTTGCTGGTGAAGTACTTGAAGTCAATGATAACATTGAAAGAGCCCTCAATGCTAATAAA
GAATTAGCTGGAAAAGAAAATGGTTTGTTTGAAGGTAATTTATTTATTTATTTCTAAATT
ATTACAAAAATAATCCTGCAATTAATCAATCAATTAGACTTTTATTTGTATCTTGCCTAA
TAAATCAAGCTAAATTATCTCCCAAAAGATAATTAAAGGAATATATAAATAAATAAACAA
AAAATTAATTGTCAAAAAATTGATTAATTTCTGTTTTTATTTTTTAATCTTTTTTTTAGC
TTTCTAACTGGATGAAATAATTAATTAATAAATCTTTCTAAAATAATCTTAGGTACAATC
ATGACCCAAAAAATCTTAGAACAAATCTTATAAAGAAATGGTATTGTTAAACTTAATCCT
GAAGGTGAAAAGTTTGATCCTAACTTCCATGATGCTCTCTGCCAAGTTCCTGATCCCACC
AAAGAATCTGGTAGCGTTGCCTTCGTTGCCCAAACTGGTTACAAAATTTACGATAGAGTC
TTACGTCCTGCTAAAGTTGGTGTTACTTACAAGAACTGA