Tian M, Agreiter C, Loidl J (2020) Spatial constraints on chromosomes are instrumental to meiotic pairing. Journal of cell science 133(22): PUBMED:33172984
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Identifiers and Description
Gene Model Identifier
TTHERM_00527180
Standard Name
GRL1 ( GRanule Lattice)
Aliases
PreTt06450 | 66.m00249 | p40 | 3722.m00106
Description
GRL1 hypothetical protein; Acidic- calcium-binding structural protein of dense core granules; translated as a pro-protein precursor; contains coiled-coil region; assembles into a lattice capable of regulated expansion; necessary for proper granule size and shape
Ref:15958493: Cowan AT, Bowman GR, Edwards KF, Emerson JJ, Turkewitz AP (2005) Genetic, genomic, and functional analysis of the granule lattice proteins in Tetrahymena secretory granules. Molecular biology of the cell 16(9):4046-60
Ref:15537088: Jacobs ME, Cortezzo DE, Klobutcher LA (2004) Assessing the effectiveness of coding and non-coding regions in antisense ribosome inhibition of gene expression in Tetrahymena. The Journal of eukaryotic microbiology 51(5):536-41
Ref:14690495: Turkewitz AP (2004) Out with a bang! Tetrahymena as a model system to study secretory granule biogenesis. Traffic (Copenhagen, Denmark) 5(2):63-8
Ref:12435750: Bradshaw NR, Chilcoat ND, Verbsky JW, Turkewitz AP (2003) Proprotein processing within secretory dense core granules of Tetrahymena thermophila. The Journal of biological chemistry 278(6):4087-95
Ref:11779800: Bowman GR, Turkewitz AP (2001) Analysis of a mutant exhibiting conditional sorting to dense core secretory granules in Tetrahymena thermophila. Genetics 159(4):1605-16
Ref:9450970: Verbsky JW, Turkewitz AP (1998) Proteolytic processing and Ca2+-binding activity of dense-core vesicle polypeptides in Tetrahymena. Molecular biology of the cell 9(2):497-511
Ref:9380694: Haddad A, Turkewitz AP (1997) Analysis of exocytosis mutants indicates close coupling between regulated secretion and transcription activation in Tetrahymena. Proceedings of the National Academy of Sciences of the United States of America 94(20):10675-80
Ref:8991090: Chilcoat ND, Melia SM, Haddad A, Turkewitz AP (1996) Granule lattice protein 1 (Grl1p), an acidic, calcium-binding protein in Tetrahymena thermophila dense-core secretory granules, influences granule size, shape, content organization, and release but not protein sorting or condensation. The Journal of cell biology 135(6 Pt 2):1775-87
Ref:2065648: Turkewitz AP, Madeddu L, Kelly RB (1991) Maturation of dense core granules in wild type and mutant Tetrahymena thermophila. The EMBO journal 10(8):1979-87