Identifiers and Description

Gene Model Identifier

TTHERM_00895640

Standard Name

GPX4 (Glutathione PeroXidase)

Aliases

PreTt21946 | 159.m00054

Description

GPX4 phospholipid hydroperoxide glutathione peroxidase

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• glutathione peroxidase activity (IEA) | GO:0004602

Biological Process

• response to oxidative stress (IEA) | GO:0006979
• oxidation-reduction process (IEA) | GO:0055114

Domains

• ( PF00255 ) glutathione peroxidase
• ( PF08534 ) redoxin family protein
• ( PF00578 ) antioxidant, AhpC/TSA family
• ( TIGR02540 ) putative glutathione peroxidase Gpx7

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.5%

TetraMine Data

TTHERM_00895640

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_04307.1	3.0002015969469427e-102	glutathione peroxidase (176 aa )
WormBase	WBGene00009165	2.0000236365077126e-43	locus:gpx-1 Glutathione pero xidase 1 status:Partially_co nfirmed UniProt:O02621 pro tein_id:CAB03004.1
Oxytricha	Contig14526.0.g10	5.998886722426197e-42	Glutathione peroxidase
SGD	YIR037W	1.9993430003514377e-39	HYR1 Thiol peroxidase that fun ctions as a hydroperoxide rece ptor to sense intracellular hy droperoxide levels and transdu ce a redox signal to the Yap1p transcription factor
Stentor Coeruleus	SteCoe_40905	2.1151310375910805e-19

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00895640(coding)
ATGATCAACGGTTCTGAATAAATTTAAAGCAACACATCTAGCTTATATGAGCTTTCCGCT
ATAGATATCAATGGCTAAAATGTTTCTCTGAAGAATTTCAATAATAAAAAGGCTATTATT
GTTGTAAATGTAGCTTGTAAATGTGGTCTTACTTCTGATCACTATACCTAACTTGTTGGC
CTTTACAAATAGTACAAATCTCAAGGATTAGAAATCTTGGCTTTTCCCTGTAACTAATTT
GGTCAATAAGAGCCTTGGGCTGAATCTGAAATTCTTTCATACACTCAAAAGACCTTTAAT
GTTGACTTCCCACTTTTCTCAAAGATTGATGTGAATGGTGAAAATACTCATCCTGTTTAC
AAATATTTAAGAAGAAACTCAGAGCTATTTTAAAATAACTCTGCAACTAAGATTCCATGG
AATTTTGCAAAATTCTTAATTGATGGAAAGACAGGTAAAGTGATTTCTTACTTCAATCCT
AAGGTGAATCCAAATGAAATGGAATAATAAATAAAATAACTTTTATAATGA

>TTHERM_00895640(protein)
MINGSEQIQSNTSSLYELSAIDINGQNVSLKNFNNKKAIIVVNVACKCGLTSDHYTQLVG
LYKQYKSQGLEILAFPCNQFGQQEPWAESEILSYTQKTFNVDFPLFSKIDVNGENTHPVY
KYLRRNSELFQNNSATKIPWNFAKFLIDGKTGKVISYFNPKVNPNEMEQQIKQLLQ

>TTHERM_00895640(gene)
ATGATCAACGGTTCTGAATAAATTTAAAGCAACACATCTAGCTTATATGAGCTTTCCGCT
ATAGATATCAATGGCTAAAATGTTTCTCTGAAGAATTTCAATAATAAAAAGGCTATTATT
GTTGTAAATGTAGCTTGTAAATGTGGTCTTACTTCTGATCACTATACCTAACTTGTTGGC
CTTTACAAATAGTACAAATCTCAAGGATTAGAAATCTTGGCTTTTCCCTGTAACTAATTT
GGTCAATAAGAGCCTTGGGCTGAATCTGAAATTCTTTCATACACTCAAAAGACCTTTAAT
GTTGACTTCCCACTTTTCTCAAAGATTGATGTGAATGGTGAAAATACTCATCCTGTTTAC
AAATATTTAAGAAGAAACTCAGAGCTATTTTAAAATAACTCTGCAACTAAGATTCCATGG
AATTTTGCAAAATTCTTAATTGATGGAAAGACAGGTAAAGTGATTTCTTACTTCAATCCT
AAGGTGAATCCAAATGAAATGGAATAATAAATAAAATAACTTTTATAATGA