Identifiers and Description

Gene Model Identifier

TTHERM_00633170

Standard Name

GPR37 (Gene Protein coupled Receptor 37)

Aliases

PreTt27986 | 90.m00150 | GPCR37

Description

7 transmembrane receptor (secretin family) protein; G protein coupled receptor; demonstrates chemorepellent receptor activity in the presence of conditioned supernatant factor

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• integral component of membrane (IEA) | GO:0016021

Molecular Function

• cAMP binding (IEA) | GO:0030552
• G protein-coupled receptor activity (IEA) | GO:0004930

Biological Process

• regulation of chemorepellent activity (IMP) | GO:1903667 | Ref:28685161
• G protein-coupled receptor signaling pathway (IEA) | GO:0007186

Domains

• ( PF05462 ) Slime mold cyclic AMP receptor
• ( PF00002 ) 7 transmembrane receptor (Secretin family)
• ( PF01534 ) Frizzled/Smoothened family membrane region
• ( PF00001 ) 7 transmembrane receptor (rhodopsin family)

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 15%

TetraMine Data

TTHERM_00633170

WebApollo

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Tetrahymena Stock Center

• ( SD01667 ) Macronucleus: GPCR3::neo3

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_15804.1	9.997093137033517e-262	7 transmembrane receptor secre tin family protein (328 aa)
DictyBase	DDB_G0283615	3.9992896861436003e-19	rpkA on chromosome: 4 position 1020192 to 1022856
Stentor Coeruleus	SteCoe_5578	4.248354255291589e-18

General Information

No Data fetched for General Information

Associated Literature

1. Ref:28685161: Zou D, Hennessey TM (2017) Behavioral Effects of a Chemorepellent Receptor Knockout Mutation in Tetrahymena thermophila. mSphere 2(4):

Sequences

>TTHERM_00633170(coding)
ATGACGATTGTTTCTAACCACAATTAGGTCAACATTATATAGATTATAGCTATTGTTGTC
AGCTCTTTTTCTCTTCTAGGAGCTATATTTATTATTGGAATATTTTTGAGTTTCAAAAAG
CTCAGGGTTTTCCCCTTTATATATGTCTTTTGGCTCAGTGTAAGTGACTTAATATCTTCT
ATAGGGTACCTTCTTGTTACTGACTCGATTGGAGACACTCCTGAATAGCTTCAAGAGGCA
AATTTTACTTGTAAAACTTAGGCTTTAATGATTAATTTTGGATAGCTTGCCTCTATTTGT
TGGACTGCAGTTATTGCCTGGACTCTCTACAACTCCACCGTTAAAGTGGTAACAAACTTA
CAACAAAAAACAGAAACAAAAATGGTTGCGATTGCTTTTGGATTTCCCCTAATTATGTCA
TTGATACCTTTAATTTTAAATGAATATGGCCCATAAGGAGGCTGGTGCTGGATAAAAAGT
GAAGGCAGCAATAAAGTATTAACATTTATTTTGGTAGGAATAGAATTTTATATTCCTCTT
TGGATAGCATTCGTATTTAATGGCATAACAATATACAGAGTAATCAAATATGTCAAGAGT
ATAACTCAAGATAAAAATTAGCTGAAACTAATCAATAGACTAACACTATATCCTCTTATT
TTATTGGTTTGCTGGAGTGCTGGTACCGTAGAAAGAGTATTTGATTTCATCGGTATCTCG
TCAGAGATACTTTCATATTTGCACATCTTCTTTGGTGGATTGTAAGGATTTTTTAATGCT
TGTGTTTACGGTCTCAATTCAAATGTCCGTAAAGTTATCAGAGAAAATCTATGCTCAAGC
CTACCATGCTTTGCAAGTGCATATATATATGAAGAATAAAACCTTAATGAAGCTGAAGAT
CATCAGCAAGATAGTAAAAAAACTGCATCCATATCCTCTGGCGAAGGCCAAGTTGAAATG
GAACAACTTAATCAATGA

>TTHERM_00633170(protein)
MTIVSNHNQVNIIQIIAIVVSSFSLLGAIFIIGIFLSFKKLRVFPFIYVFWLSVSDLISS
IGYLLVTDSIGDTPEQLQEANFTCKTQALMINFGQLASICWTAVIAWTLYNSTVKVVTNL
QQKTETKMVAIAFGFPLIMSLIPLILNEYGPQGGWCWIKSEGSNKVLTFILVGIEFYIPL
WIAFVFNGITIYRVIKYVKSITQDKNQLKLINRLTLYPLILLVCWSAGTVERVFDFIGIS
SEILSYLHIFFGGLQGFFNACVYGLNSNVRKVIRENLCSSLPCFASAYIYEEQNLNEAED
HQQDSKKTASISSGEGQVEMEQLNQ

>TTHERM_00633170(gene)
ATGACGATTGTTTCTAACCACAATTAGGTCAACATTATATAGATTATAGCTATTGTTGTC
AGCTCTTTTTCTCTTCTAGGAGCTATATTTATTATTGGAATATTTTTGAGTTTCAAAAAG
CTCAGGGTTTTCCCCTTTATATATGTCTTTTGGCTCAGTGTAAGTGACTTAATATCTTCT
ATAGGGTACCTTCTTGTTACTGACTCGATTGGAGACACTCCTGAATAGCTTCAAGAGGCA
AATTTTACTTGTAAAACTTAGGCTTTAATGATTAATTTTGGATAGCTTGCCTCTATTTGT
TGGACTGCAGTTATTGCCTGGACTCTCTACAACTCCACCGTTAAAGTGGTAACAAACTTA
CAACAAAAAACAGAAACAAAAATGGTTGCGATTGCTTTTGGATTTCCCCTAATTATGTCA
TTGATGTAATCATAATTTATTACTTACTTGAGAAAATTACGTTTTTCATACTATTAAAAT
ATCTTTAATACTTTGCTTTATTTATTAACTTTATGATAAATTAAATAGACCTTTAATTTT
AAATGAATATGGCCCATAAGGAGGCTGGTGCTGGATAAAAAGTGAAGGCAGCAATAAAGT
ATTAACATTTATTTTGGTAGGAATAGAATTTTATATTCCTCTTTGGATAGCATTCGTATT
TAATGGCATAACAATATACAGAGTAATCAAATATGTCAAGAGTATAACTCAAGATAAAAA
TTAGCTGAAACTAATCAATAGACTAACACTATATCCTCTTATTTTATTGGTTTGCTGGAG
TGCTGGTACCGTAGAAAGAGTATTTGATTTCATCGGTATCTCGTCAGAGATACTTTCATG
TAATTTATTTTTATTAAGCTATAGTAAAATAAGTAAAATTAATATTAATTTATTAATTTA
GATTTGCACATCTTCTTTGGTGGATTGTAAGGATTTTTTAATGCTTGTGTTTACGGTCTC
AATTCAAATGTCCGTAAAGTTATCAGAGAAAATCTATGCTCAAGCCTACCATGCTTTGCA
AGTGCATATATATATGAAGAATAAAACCTTAATGAAGCTGAAGATCATCAGCAAGATAGT
AAAAAAACTGCATCCATATCCTCTGGCGAAGGCCAAGTTGAAATGGAACAACTTAATCAA
TGA