Identifiers and Description

Gene Model Identifier

TTHERM_00248420

Standard Name

FZY1 (FiZzY 1)

Aliases

PreTt02538 | 21.m00369

Description

FZY1 WD domain G-beta repeat protein; Fizzy/CDC20/CDH1 family protein; homolog of S. cerevisiae CDC20- a cell cycle regulated activator of the anaphase-promoting complex /cyclosome (APC/C)- which directs ubiquitination of various targets

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF00400 ) WD domain, G-beta repeat
• ( PF08662 ) Eukaryotic translation initiation factor eIF2A

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.5%

TetraMine Data

TTHERM_00248420

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_00459.1	9.997093137033517e-262	hypothetical protein (570 aa)
Oxytricha	Contig16130.0.g41	1.999447289884935e-116	WD domain, G-beta repeat
DictyBase	DDB_G0285601	1.0001155149984988e-113	cdc20 on chromosome: 4 positio n 3433247 to 3434746
WormBase	WBGene00001510	1.9991716194688635e-85	locus:fzr-1 status:Partially _confirmed UniProt:Q09649 protein_id:CAA87433.1
SGD	YGL003C	8.002927718340724e-80	CDH1 Cell-cycle regulated acti vator of the anaphase-promotin g complex/cyclosome (APC/C), w hich directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to spe cific substrates including Cdc 20p, Ase1p, Cin8p and Fin1p
Stentor Coeruleus	SteCoe_20239	1.0112214926104486e-43

General Information

No Data fetched for General Information

Associated Literature

1. Ref:SUPR000043

Sequences

>TTHERM_00248420(coding)
ATGTTTTGGAAGGATGAAAACGTTTTTAAAAATAAGCATTCAGTAGGAAACAATCCACTC
TTTGGTGGTAAAGAAAAGCCTGCTTAGTCAGATTGTAGATTTATCCCAAGTAGAAGAGGA
ACTAACACATCTTACAATTAATATTTACTCAAAGAGAATATCAACACATAAAACATCATA
AATTAAAACGGTTCATGCATTTCCTAAAACTTTGAAACATCTTCTCAAACTTCATCAACA
ACAGCTACTACTCAAAGCAGCTTTTTCCACTTCGGTACCTCAGGATCAGGCAATATTTTC
AATCAACAATAAAGCTAACAACAATCAGGAGTAATCAATTCTGATGAATAAACTACTAAC
AGCAATTAGTCTATGATTCATAATGCTAGTTCATCCTCTTCCACTTAAACTTCAGGTATA
AATAGCAGTAATCTGAATATTAGTTACTGCAATAGCAGCGTAAACTCATACCAGAAGCTG
ATGGAAGACTGCCTCTTTTAGCAGGAAAAGAAAAATCAAAAAAAAAGAGTGTTAAATTTT
AGAAGTGAATCAGACATGCCAATTCCTTTGGACAAGTGCATTAGTAAGACTTTTGAGTAA
GCAAATCAACAATTCATGGAAACAAATAAAATAATGAGATATATTTCTCCTATGCCAGAA
AGAATACTTGATGCACCTTAACTTAGCGATGATTACTACCTTAATTTAATGGATTGGGGA
GACAGTGGTACTGACAATAAAGGCACTTTAGCAATATGTCTTGGAAGCGAAGTTTATTTA
TGGGATGAATATGAAATCATAAACCTTTTTAAGGCTAATTAAAATATTTAGGCTACTAGT
GTCAGCTGGATGAATTTAAAAAAGAAAAATTGCTTGGCCGTTGGCTTCTCTGATAATACA
ATATAGCTTTGGGATACTGAAAAGTGCATTCCATACAGAATTCTCAAAGGTCATACCGGT
AGAGTATCTTCACTATCCTGGAATAATTACATATTGTCAAGTGGAAGCAGAGACACTTAA
ATAATTAATCACGACATTCGTTAAAAAAATAATATAATAAAGCGCTTTTAAGGCCATGAA
TAGGAGGTATGTGGATTAAAGTGGTCTCCCGATGGTACTCAGCTAGCTTCAGGAGGTAAC
GATAATACACTCAGAATTTGGGATATTAATTATGCTTAAAATAATATCAACAACAATAAC
ACCTCTAGTTCAAGTAGTTAGAGTGCTTCTCCAAGTTATCAGCGTGCCTGTTTTTATAAT
CACAAAGCAGCTGTAAAGGCTCTAGCATGGTGTCCTTGGTAAAAAAATCTTTTAGCAAGT
GGAGGGGGAACCTAGGATAAAACAATTAAGTTCTGGAATACTGATAAAATGGAATTAGTC
AATTCAATCAACTGTGGTAGTTAGGTATGCTCAATTTTATGGAATCCTTAGGACAAAGAA
CTCATAAGCTCTCATGGGTTCTAAGATAACTAATTGATTGTTTGGAGTTACCCATCGATG
CAGAAAATTACTGAGTTACATGGACATACAAATAGAGTGTTACATATGGCGCTTTCTCCA
GATGGTTCTACCGTATGCTCAGCCTCTTCCGACGAAACCTTAAGATTTTGGAAGGTCTTC
CCTGGTTCTAGATATGATAGACATGATTATGATGACTCGAATCCGTTCACAAAACACAAA
AGAGATGGATTATCTTCATAAAATCTATTCATCAGATGA

>TTHERM_00248420(protein)
MFWKDENVFKNKHSVGNNPLFGGKEKPAQSDCRFIPSRRGTNTSYNQYLLKENINTQNII
NQNGSCISQNFETSSQTSSTTATTQSSFFHFGTSGSGNIFNQQQSQQQSGVINSDEQTTN
SNQSMIHNASSSSSTQTSGINSSNLNISYCNSSVNSYQKLMEDCLFQQEKKNQKKRVLNF
RSESDMPIPLDKCISKTFEQANQQFMETNKIMRYISPMPERILDAPQLSDDYYLNLMDWG
DSGTDNKGTLAICLGSEVYLWDEYEIINLFKANQNIQATSVSWMNLKKKNCLAVGFSDNT
IQLWDTEKCIPYRILKGHTGRVSSLSWNNYILSSGSRDTQIINHDIRQKNNIIKRFQGHE
QEVCGLKWSPDGTQLASGGNDNTLRIWDINYAQNNINNNNTSSSSSQSASPSYQRACFYN
HKAAVKALAWCPWQKNLLASGGGTQDKTIKFWNTDKMELVNSINCGSQVCSILWNPQDKE
LISSHGFQDNQLIVWSYPSMQKITELHGHTNRVLHMALSPDGSTVCSASSDETLRFWKVF
PGSRYDRHDYDDSNPFTKHKRDGLSSQNLFIR

>TTHERM_00248420(gene)
ATGTTTTGGAAGGATGAAAACGTTTTTAAAAATAAGCATTCAGTAGGAAACAATCCACTC
TTTGGTGGTAAAGAAAAGCCTGCTTAGTCAGTAATAAATACTTCATTTTCTAGTTTCTCC
TTTTACTGTAAAAGGAGTGTTTGATAACATTACGCTCTTTTAATTATGCCCAATTATTAA
AAGCTTCAATCTTTTGGACGTTCCAATCAATGATCGACTTACAAAAGGAGGCGAATATTA
AAATAGAAGTGGCTGATTAAAGGAGTTTGTTTAAACATTCTATTAAATGGCTCTTTAATA
AATCTTATGACATTTTTGTTTTTTTATATAAAGGATTGTAGATTTATCCCAAGTAGAAGA
GGAACTAACACATCTTACAATTAATATTTACTCAAAGAGAATATCAACACATAAAACATC
ATAAATTAAAACGGTTCATGCATTTCCTAAAACTTTGAAACATCTTCTCAAACTTCATCA
ACAACAGCTACTACTCAAAGCAGCTTTTTCCACTTCGGTACCTCAGGATCAGGCAATATT
TTCAATCAACAATAAAGCTAACAACAATCAGGAGTAATCAATTCTGATGAATAAACTACT
AACAGCAATTAGTCTATGATTCATAATGCTAGTTCATCCTCTTCCACTTAAACTTCAGGT
ATAAATAGCAGTAATCTGAATATTAGTTACTGCAATAGCAGCGTAAACTCATACCAGAAG
CTGATGGAAGACTGCCTCTTTTAGCAGGAAAAGAAAAATCAAAAAAAAAGAGTGTTAAAT
TTTAGAAGTGAATCAGACATGCCAATTCCTTTGGACAAGTGCATTAGTAAGACTTTTGAG
TAAGCAAATCAACAATTCATGGAAACAAATAAAATAATGAGATATATTTCTCCTATGCCA
GAAAGAATACTTGATGCACCTTAACTTAGCGATGATTACTACCTTAATTTAATGGATTGG
GGAGACAGTGGTACTGACAATAAAGGCACTTTAGCAATATGTCTTGGAAGCGAAGTTTAT
TTATGGGATGAATATGAAATCATAAACCTTTTTAAGGCTAATTAAAATATTTAGGCTACT
AGTGTCAGCTGGATGAATTTAAAAAAGAAAAATTGCTTGGCCGTTGGCTTCTCTGATAAT
ACAATATAGCTTTGGGATACTGAAAAGTGCATTCCATACAGAATTCTCAAAGGTCATACC
GGTAGAGTATCTTCACTATCCTGGAATAATTACATATTGTCAAGTGGAAGCAGAGACACT
TAAATAATTAATCACGACATTCGTTAAAAAAATAATATAATAAAGCGCTTTTAAGGCCAT
GAATAGGAGGTATGTGGATTAAAGTGGTCTCCCGATGGTACTCAGCTAGCTTCAGGAGGT
AACGATAATACACTCAGAATTTGGGATATTAATTATGCTTAAAATAATATCAACAACAAT
AACACCTCTAGTTCAAGTAGTTAGAGTGCTTCTCCAAGTTATCAGCGTGCCTGTTTTTAT
AATCACAAAGCAGCTGTAAAGGCTCTAGCATGGTGTCCTTGGTAAAAAAATCTTTTAGCA
AGTGGAGGGGGAACCTAGGATAAAACAATTAAGTTCTGGAATACTGATAAAATGGAATTA
GTCAATTCAATCAACTGTGGTAGTTAGGTATGCTCAATTTTATGGAATCCTTAGGACAAA
GAACTCATAAGCTCTCATGGGTTCTAAGATAACTAATTGATTGTTTGGAGTTACCCATCG
ATGCAGAAAATTACTGAGTTACATGGACATACAAATAGAGTGTTACATATGGCGCTTTCT
CCAGATGGTTCTACCGTATGCTCAGCCTCTTCCGACGAAACCTTAAGATTTTGGAAGGTC
TTCCCTGGTTCTAGATATGATAGACATGATTATGATGACTCGAATCCGTTCACAAAACAC
AAAAGAGATGGATTATCTTCATAAAATCTATTCATCAGATGA