Identifiers and Description

Gene Model Identifier

TTHERM_00218410

Standard Name

FRS2 (Phenylalanyl(F)-tRNA Synthetase 2)

Aliases

PreTt22268 | 18.m00294 | 3701.m00054

Description

Phenylalanyl-tRNA synthetase; beta subunit family protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• RNA binding (IEA) | GO:0003723
• magnesium ion binding (IEA) | GO:0000287
• ATP binding (IEA) | GO:0005524
• phenylalanine-tRNA ligase activity (IEA) | GO:0004826

Biological Process

• phenylalanyl-tRNA aminoacylation (IEA) | GO:0006432
• translation (IEA) | GO:0006412

Domains

• ( PF03483 ) B3/4 domain
• ( PF03484 ) phenylalanine-tRNA synthetase, B5 domain
• ( TIGR00471 ) phenylalanyl-tRNA synthetase, beta subunit
• ( TIGR00472 ) phenylalanyl-tRNA synthetase, beta subunit

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.3%

TetraMine Data

TTHERM_00218410

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_06614.1	9.997093137033517e-262	phenylalanyl-tRNA synthetase, beta subunit protein (591 aa)
WormBase	WBGene00001498	6.002322951831963e-178	locus:fars-3 Phenylalanine-- tRNA ligase beta subunit sta tus:Confirmed UniProt:Q19713 protein_id:CAA90360.1
DictyBase	DDB_G0277303	2.0002969069156684e-168	phesB on chromosome: 2 positio n 7623909 to 7626465
Oxytricha	Contig14504.0.g56	1.9994249217050915e-157	B3/4 domain
SGD	YLR060W	9.995193436412938e-154	FRS1 Beta subunit of cytoplasm ic phenylalanyl-tRNA synthetas e, forms a tetramer with Frs2p to generate active enzyme; ab le to hydrolyze mis-aminoacyla ted tRNA-Phe, which could cont ribute to translational qualit y control
Stentor Coeruleus	SteCoe_14429	6.714184288211594e-79

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00218410(coding)
ATGCCTATTGTCTCTGTTAACATTAAAAATTTCTTCAAAAAGTTAGGAAAGGAACTCAAA
TTCCACGAATTGGAAGAATTATGCTTCGAATATGGTATCGAAGTAGAAGAAAAGGAAGTC
TCCAAGAAAAATAAGAAGTCAGGCAAAGAAGAAAAAGTTAAAGAATATGCTTTTGAAGTT
GGTGCTAACAGACCTGATTTACTCTCTGTAGAAACTCTTACTTAAGCTTTGGGAGTCTTT
ATTGGTACTCGCCAACCCCCTCAATATACAGTAAAGCCTGTTGAACAAAGATAAAAGATT
ATTGTTAAGAAGGATTGCAAGCGTATTAGACCTTTTGTTGTTGGTGCTGTTTTGAGAAAT
GTTACCTTCACTCAAGAATCCTATGATTCTTTCATTGACTTCTAAGATAAGTTACATCAC
AATCTTTGTCGTAGAAGAAGATTAGTCGCTATTGGTACTCATGATTTAGATACCATATAA
GGTCCTTTTACTTATGATGCTAGAAACCCTGCTGACATCAAGTTTGTACCTCTCGATAAA
ACCGAAAGCATGGATGGAAACAGACTTATGGAATTTTACGAAAAAGACTCTCACTTAAAA
GATTTCTTACCCATTATCAGAAATTCTCCTGTTTATCCTGTAATTCTTGACTCAAATAAT
GTTGTATGCTCTCTTCCTCCCATCATTAATGGTGACCACTCTAAAATTAAACTTACTACT
AAAAACGTTTTTATTGAATCAACTGCTACTGACTATACTAGAGCTTTGATTGCCTTAAAC
TGTTTAGTTGCTGCCTTCTCTGAATATTGTGCTGAACCCTACACCGTCGAAGAAGTTGAA
ATTCATTATGAAGAAGAAAATAGAACAGATATTACTCCCTAATTTACTATTAATAAATTT
TAAACTAAAATTTCTCACTTAAACAGCGTTGGTACCATCAATGTTACTGCAGAATAAGCT
TGCAAATTATTAGAAAGAATGAGTCTTACTGCAAAAGTTCTTAATAATGATGAAATCGAA
GTAGCTGTCCCAATCACCAGAGGAGATATTCTTTAAGAGTGTGATATTATTGAAGACGTT
TGCATTGCATACGGTTTCAAAAACATCAAGGCTGTTTTACCTAAAACTCCTACTGTTGGT
AAATAATTATTACTCAACAAGATGAGTGATTTGATTCGTGAAGAAATCGCTGCAGCTGGT
TATAAGGAAGGTCTTAATTTCGTTTTAGTTTCAAGAGATGATTTAACCAAAAAGCTTAAA
AAGGAAAATGATGAATAAATGATTATTATTGACAACCCCAAAACTGAAGAATTCAGCGTT
GGTAGAACTACACTTCTTCCTGGTTGCCTTAAATGGTTATCATCAAATAAAAAGAATAAG
ATCCCTATCAGTATGTTTGAAGTTGGTGATGTTATTTTGAAGGATGAAACTAGAGAAACT
AATACCAGAAACGAAAGAAGATTATGTGCTATCTACACTAATCACAACTCTGAATTAGAA
GTTGTTCATGGTTTACTTGATTATATTATGTTAAAGCTTATGGTTAACCTTGATTCTACA
GGAACTTGTAAGGCAGAAAGAAGATACAGACTTGTTCCTTCTGATGAACCTACATATTTC
TTAGATAGATAAGCTCATGTCTACTACAATGATAAGAAAATCGGAAATTTGGGTATCTTA
CATCCAGATGTTGTTAAAAATTTCGAATGGAAATATCCCGTTTCTGTTTTGGAATTAAAT
TTAGAACCTCTTATTAACGAATTCCACTAATGA

>TTHERM_00218410(protein)
MPIVSVNIKNFFKKLGKELKFHELEELCFEYGIEVEEKEVSKKNKKSGKEEKVKEYAFEV
GANRPDLLSVETLTQALGVFIGTRQPPQYTVKPVEQRQKIIVKKDCKRIRPFVVGAVLRN
VTFTQESYDSFIDFQDKLHHNLCRRRRLVAIGTHDLDTIQGPFTYDARNPADIKFVPLDK
TESMDGNRLMEFYEKDSHLKDFLPIIRNSPVYPVILDSNNVVCSLPPIINGDHSKIKLTT
KNVFIESTATDYTRALIALNCLVAAFSEYCAEPYTVEEVEIHYEEENRTDITPQFTINKF
QTKISHLNSVGTINVTAEQACKLLERMSLTAKVLNNDEIEVAVPITRGDILQECDIIEDV
CIAYGFKNIKAVLPKTPTVGKQLLLNKMSDLIREEIAAAGYKEGLNFVLVSRDDLTKKLK
KENDEQMIIIDNPKTEEFSVGRTTLLPGCLKWLSSNKKNKIPISMFEVGDVILKDETRET
NTRNERRLCAIYTNHNSELEVVHGLLDYIMLKLMVNLDSTGTCKAERRYRLVPSDEPTYF
LDRQAHVYYNDKKIGNLGILHPDVVKNFEWKYPVSVLELNLEPLINEFHQ

>TTHERM_00218410(gene)
ATGCCTATTGTCTCTGTTAACATTAAAAATTTCTTCAAAAAGTTAGGAAAGGAACTCAGT
AAAAATATTCATTACATTCTCATATAGAATAAACAATAAAATAATTATTTTATTCAAATC
TAAATTAAAATAAATTAATATGATCAGAAACATTCAAATATTTGATAATATGGATCATAA
ATGAAACAACATATTCAACAAGCTTCAATTTAACTTCTTTTCTCAAATAATAACAATTTG
AATACTAAAATCTTATCACTTTATTTAATTATGAACAGAATTCCACGAATTGGAAGAATT
ATGCTTCGAATATGGTATCGAAGTAGAAGAAAAGGAAGTCTCCAAGAAAAATAAGAAGTC
AGGCAAAGAAGAAAAAGTTAAAGAATATGCTTTTGAAGTTGGTGCTAACAGACCTGATTT
ACTCTCTGTAGAAACTCTTACTTAAGCTTTGGGAGTCTTTATTGGTACTCGCCAACCCCC
TCAATATACAGTAAAGCCTGTTGAACAAAGATAAAAGATTATTGTTAAGAAGGATGTAAT
ACATTAATTTAAAAAAAATAAATAGGAAACATTTAAATAATCCAAATAGTTTTATTCAGA
AAGCAAAAAATAAAAAAAAAGTTGATAGAAATGATATTAATTTTTTGATTTTATTCATCA
GTTAAATTGTTTTTTATTCTACCAAGCATTTGCTTTTCTGAGCTCTCTATATTTTAGCAT
TATTCTAAATTTTTATAATTTGAAAAAAGTGCAAGCGTATTAGACCTTTTGTTGTTGGTG
CTGTTTTGAGAAATGTTACCTTCACTCAAGAATCCTATGATTCTTTCATTGACTTCTAAG
ATAAGTTACATCACAATCTTTGTCGTAGAAGAAGATTAGTCGCTATTGGTACTCATGATT
TAGATACCATATAAGGTCCTTTTACTTATGATGCTAGAAACCCTGCTGACATCAAGTTTG
TACCTCTCGATAAAACCGAAAGCATGGATGGAAACAGACTTATGGAATTTTACGAAGTAA
ATTTTAAATATGTTTTAAATGAAATTTATATAATAATTTATTAATATTTGTAGAAAGACT
CTCACTTAAAAGATTTCTTACCCATTATCAGAAATTCTCCTGTTTATCCTGTAATTCTTG
ACTCAAATAATGTTGTATGCTCTCTTCCTCCCATCATTAATGGTGACCACTCTAAAATTA
AACTTACTACTAAAAACGTTTTTATTGAATCAACTGCTGTAATAAATATTTAAAAATTTT
ATTTAATTAAATTAAAATATTATTTATATTTTAAAGACTGACTATACTAGAGCTTTGATT
GCCTTAAACTGTTTAGTTGCTGCCTTCTCTGAATATTGTGCTGAACCCTACACCGTCGAA
GAAGTTGAAATTCATTATGAAGAAGAAAATAGAACAGATATTACTCCCTAATTTACTATT
AATAAATTTTAAACTAAAATTTCTCACTTAAACAGCGTTGGTACCATCAATGTTACTGCA
GAATAAGCTTGCAAATTATTAGAAAGAATGAGTCTTACTGCAAAAGTTCTTAATAATGAT
GAAATCGAAGTAGCTGTCCCAATCACCAGAGGAGGTAATAATTACAAAAAGACAAAATAT
GAAATAAACTATATTTTTAAAATTAATGTAACAGATATTCTTTAAGAGTGTGATATTATT
GAAGACGTTTGCATTGCATACGGTTTCAAAAACATCAAGGCTGTTTTACCTAAAACTCCT
ACTGTTGGTAAATAATTATTACTCAACAAGATGAGTGATTTGATTCGTGAAGAAATCGCT
GCAGCTGGTTATAAGGAAGGTCTTAATTTCGTTTTAGTTTCAAGAGATGATTTAACCAAA
AAGCTTAAAAAGGAAAATGATGAATAAATGATTATTATTGACAACCCCAAAACTGAAGAA
TTCAGCGTTGGTAGAACTACACTTCTTCCTGGTTGCCTTAAATGGTTATCATCAAATAAA
AAGAATAAGGTAATTTACTATAATTGACTACAAATAGCATAACATTTGAATTTAAAATAG
ATCCCTATCAGTATGTTTGAAGTTGGTGATGTTATTTTGAAGGATGAAACTAGAGAAACT
AATACCAGAAACGAAAGAAGATTATGTGCTATCTACACTAATCACAACTCTGAATTAGAA
GTTGTTCATGGTTTACTTGATTATATTATGTTAAAGCTTATGGTTAACCTTGATTCTACA
GGAACTTGTAAGGCAGAAAGAAGATACAGACTTGTTCCTTCTGATGGTAAGATTATTTAA
AAATAGATATTATTTAATTAACCATTTATTATTTTAGAACCTACATATTTCTTAGATAGA
TAAGCTCATGTCTACTACAATGATAAGAAAATCGGAGTAAAATTTATAATTTTCTAAAAA
TATAAATGTTAAAAAATATTTGTTTTAAAAAAAGAATTTGGGTATCTTACATCCAGATGT
TGTTAAAAATTTCGAATGGAAATATCCCGTTTCTGTTTTGGAATTAAATTTAGAACCTCT
TATTAACGAATTCCACTAATGA