Identifiers and Description

Gene Model Identifier

TTHERM_00133690

Standard Name

FRS1 (Phenylalanyl(F)-tRNA Synthetase 1)

Aliases

PreTt24292 | 10.m00341 | 3698.m00063

Description

Phenylalanyl-tRNA synthetase; alpha subunit family protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• cytoplasm (IEA) | GO:0005737

Molecular Function

• ATP binding (IEA) | GO:0005524
• phenylalanine-tRNA ligase activity (IEA) | GO:0004826
• tRNA binding (IEA) | GO:0000049

Biological Process

• phenylalanyl-tRNA aminoacylation (IEA) | GO:0006432

Domains

• ( PF01409 ) phenylalanyl-tRNA synthetase
• ( PF07377 ) Protein of unknown function (DUF1493)
• ( TIGR00470 ) O-phosphoseryl-tRNA(Cys) synthetase
• ( PF00152 ) tRNA synthetases class II (D,
• ( TIGR00468 ) phenylalanyl-tRNA synthetase, alpha subunit

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.7%

TetraMine Data

TTHERM_00133690

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_05732.1	9.997093137033517e-262	phenylalanyl-tRNA synthetase, alpha subunit protein (513 aa)
Oxytricha	Contig1385.1.g55	3.000071119766155e-172	tRNA synthetases class II core domain (F)
WormBase	WBGene00001497	9.995404496431436e-166	locus:fars-1 status:Confirme d UniProt:Q86B36 protein_i d:CCD67615.1
SGD	YFL022C	4.001878793042739e-150	FRS2 Alpha subunit of cytoplas mic phenylalanyl-tRNA syntheta se, forms a tetramer with Frs1 p to form active enzyme; evolu tionarily distant from mitocho ndrial phenylalanyl-tRNA synth etase based on protein sequenc e, but substrate binding is si milar
DictyBase	DDB_G0287141	5.997984985848154e-146	phesA on chromosome: 4 positio n 5374001 to 5375464
Stentor Coeruleus	SteCoe_30854	2.7086952666810816e-76

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00133690(coding)
ATGGAAAAGAATTACACTTAATTAATTTTAACTGAATTAGAGTAAAATGGTGAAATCCCT
GATACTCTATTATTGGCAAAGAAATTTGAAATTGAACATCAAGAATTAGTTGGTTATTTA
AATTCTTTGCTTTTAGAGAACTACATTACTTAAGAAGTTAAGGAAATTTAAAGATGGGTA
CTTTTATAAGAAGGTTTAGATAATGTTACTAATGGCACTCCCGAATTCAGAGTGTTCTAG
GGTATCCCTGCTGAAGGTATTTCAAAGAATGATTTAGAAGCTAAATTTGATCCCAATGTT
TTCAAGTTCGGTTTATAAAATGGTATGAAAAAGAAGTGGTTCAAGATTAAGGACGGTCTT
ATTCAAAAAGAAGTAGCTGAAGTAGTCGATGAAGATGCTGTTCTTTTAAAAAGAATTGAA
TCTAACAGCAATTTGGAAGATATTAAAAAGGACGTTTTCGATAATCTTAAGAAGAGAAAG
ATTATTTCTTAGGAAGTTATCAAATATTTCAAAATTAATAAAGGTGCTGAATTCAAGCCC
ATTTATGTTGAACTTGAATCTGATTTAACTTATGATATGGTTAAGAACTACGATGATTTT
GTCAAGAATGAAGATGGAACAATTAAATCAAATACTGAACTCGCTAAATAATTCAAAAAA
TATAATTGGAATTCTGTTGGTAAAGATATAAAAACTGGTAACTTGCATCCTTTGATGAAA
GTCAGAAAATAATTCAGAGAAGTTCTTATTGAAATGGGATTCGAAGAAATGGCTACCAAC
CAATATGTTGAAAGTGGTTTCTGGAACTTCGATGCCCTTTTCTAACCTTAATAACATCCT
GCCAGAGATGCTCACGATACTTTCTTCATTAGAGAACCTGCTCACAGCAAGAATTTAGAT
CCTGAATACTGGGAAAGAGTTAAGAAAACTCACGAAGTAGGTGGTTATGGATCTATTGGT
TATCGTTATGATTGGAGTTATGATGAAGCCAAAAAGAACATCTTCCGTACTCACACAACT
GCTGTTTCATCTAAAATGTTAAGACAAATTGCCATCGAATATGCTAAGGACGGCGTTTTC
AAACCTAGAAAATTCTTCTCTATTGATAGAGTCTTCAGAAATGAAAGCTTAGATGCTACT
CACTTGGCTGAATTCCATTAAATTGAAGGTGTTATCGCTGATAAGAATGTTGGTCTTGGT
GAACTACTTGGAGTTATTACTGAATTCTTTGCTAAAATAGGTATTACTGGCTTGAAGTTT
AAGCCCACATATAACCCATACACAGAACCATCCTTGGAAATTCATGGTTTCCATCCTGGT
TTGAATAAAGTCATTGAATTAGGTAACAGTGGTGTTTTCAGACCTGAAATGTTACGTCCC
ATGGGATTACCAGAAGATATTTAAGTTTTAGGTTGGGGTCTTGGTTTAGAAAGACCTACA
ATGATATAATATAAATTCAAAAATATCAGAGATCTTCTTGGTTACGGTGTAGATATGAAA
CTCCTTAAGGAAAATCCTATTTGCTGTTTCAAGAATTGA

>TTHERM_00133690(protein)
MEKNYTQLILTELEQNGEIPDTLLLAKKFEIEHQELVGYLNSLLLENYITQEVKEIQRWV
LLQEGLDNVTNGTPEFRVFQGIPAEGISKNDLEAKFDPNVFKFGLQNGMKKKWFKIKDGL
IQKEVAEVVDEDAVLLKRIESNSNLEDIKKDVFDNLKKRKIISQEVIKYFKINKGAEFKP
IYVELESDLTYDMVKNYDDFVKNEDGTIKSNTELAKQFKKYNWNSVGKDIKTGNLHPLMK
VRKQFREVLIEMGFEEMATNQYVESGFWNFDALFQPQQHPARDAHDTFFIREPAHSKNLD
PEYWERVKKTHEVGGYGSIGYRYDWSYDEAKKNIFRTHTTAVSSKMLRQIAIEYAKDGVF
KPRKFFSIDRVFRNESLDATHLAEFHQIEGVIADKNVGLGELLGVITEFFAKIGITGLKF
KPTYNPYTEPSLEIHGFHPGLNKVIELGNSGVFRPEMLRPMGLPEDIQVLGWGLGLERPT
MIQYKFKNIRDLLGYGVDMKLLKENPICCFKN

>TTHERM_00133690(gene)
ATGGAAAAGAATTACACTTAATTAATTTTAACTGAATTAGAGTAAAATGGTGAAATCCCT
GATACTCTATTATTGGCAAAGAAATTTGAAATTGAACATCAAGAATTAGTTGGTTATTTA
AATTCTTTGCTTTTAGAGAACTACATTACTTAAGAAGTTAAGGAAATTTAAAGATGGGTA
CTTTTATAAGAAGGTTTAGATAATGTTACTAATGGCACTCCCGAATTCAGAGTGTTCTAG
GGTATCCCTGCTGAAGGTAAATTTATTTTATCTTTATTTGAATTCATACCTTAAAACAGT
TTACAGCAATTTCTAAAAAATAGTTTTACAGCTTAGATTTATTATAAAATTTGGCACATT
TCAAAAAATATTTTTTAAATTTGTATGAATTTAAAGCTCAATAAGCAAACAAATAAATGA
TTTATTTTAACTAATGATAAATTTAGGTATTTCAAAGAATGATTTAGAAGCTAAATTTGA
TCCCAATGTTTTCAAGTTCGGTTTATAAAATGGTATGAAAAAGAAGTGGTTCAAGATTAA
GGACGGTCTTATTCAAAAAGAAGTAGCTGAAGTAGTCGATGAAGATGCTGTTCTTTTAAA
AAGAATTGAATCTAACAGCAATTTGGAAGATATTAAAAAGGACGTTTTCGATAATCTTAA
GAAGAGAAAGATTATTTCTTAGGAAGTTATCAAATATTTCAAAATTAATAAAGGTGCTGA
ATTCAAGCCCATTTATGTTGAACTTGAATCTGATTTAACTTATGATATGGTTAAGAACTA
CGATGATTTTGTCAAGAATGAAGATGGAACAATTAAATCAAATACTGAACTCGCTAAATA
ATTCAAAAAATATAATTGGAATTCTGTTGGTAAAGATATGTAAATAACCTATTTGAATAT
TTTTATGTTAATGCTGCTTAAGATATTATATTTTTATTTTTAAATAAACGACTTTTATAC
TAAAAAATACGATTTATAAAAATAGAAAAACTGGTAACTTGCATCCTTTGATGAAAGTCA
GAAAATAATTCAGAGAAGTTCTTATTGAAATGGGATTCGAAGAAATGGCTACCAACCAAT
ATGTTGAAAGTGGTTTCTGGAACTTCGATGCCCTTTTCTAACCTTAATAACATCCTGCCA
GAGATGCTCACGATACTTTCTTCATTAGAGAACCTGCTCACAGCAAGAATTTAGATCCTG
AATACTGGGAAAGAGTTAAGAAAACTCACGAAGTAGGTGGTTATGGATCTATTGGTTATC
GTTATGATTGGAGTTATGATGAAGCCAAAAAGAACATCTTCCGTACTCACACAACTGCTG
TAATTTACTGAATTTAACCTTTAAAAATAATTAATTAATAAATAGCTAGAAAAAATAAAT
AATTAGCATAAAAAATATTTAGAATATTATCAAAAAAAATTAGCTAAGCAAATATTATTG
AAATAATAATTAGGTTTCATCTAAAATGTTAAGACAAATTGCCATCGAATATGCTAAGGA
CGGCGTTTTCAAACCTAGAAAATTCTTCTCTATTGATAGAGTCTTCAGAAATGAAAGCTT
AGATGCTACTCACTTGGCTGAATTCCATTAAATTGAAGGTGTTATCGCTGATAAGAATGT
TGGTCTTGGTGAACTACTTGGAGTTATTACTGAATTCTTTGCTAAAATAGGTAATATTAT
TTTAGCTTTTATAAATAAATATTCTATTTTTTAAATTAAATCAATAAATTAAAGGTATTA
CTGGCTTGAAGTTTAAGCCCACATATAACCCATACACAGAACCATCCTTGGAAATTCATG
GTTTCCATCCTGGTTTGAATAAAGTCATTGAATTAGGTAACAGTGGTGTTTTCAGACCTG
AAATGTTACGTCCCATGGGATTACCAGAAGATATTTAAGTTTTAGGTTGGGGTCTTGGTT
TAGAAAGACCTACAATGATATAATATAAATTCAAAAATATCAGAGATCTTCTTGGTTACG
GTGTAGATATGAAACTCCTTAAGGAAAATCCTATTTGCTGTTTCAAGAATTGA