TGD | Gene Details

Identifiers and Description

Gene Model Identifier
TTHERM_00994350

Standard Name
FLP8 (FLiPpase)

Aliases
PreTt20031 | 187.m00068

Description
phospholipid-translocating P-type ATPase, flippase family protein

Genome Browser

Gene Ontology Annotations

Cellular Component
membrane (IEA) | GO:0016020
integral to membrane (IEA) | GO:0016021
Molecular Function
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism (IEA) | GO:0015662
ATP binding (IEA) | GO:0005524
ATPase activity (IEA) | GO:0016887
Biological Process
cation transport (IEA) | GO:0006812

Domains

( PF04178 ) Got1-like family
( TIGR00099 ) Cof-like hydrolase
( TIGR00338 ) phosphoserine phosphatase SerB
( PF00702 ) haloacid dehalogenase-like hydrolase
( TIGR01484 ) HAD-superfamily hydrolase, subfamily IIB
( TIGR01517 ) calcium-translocating P-type ATPase, PMCA-type
( TIGR01652 ) phospholipid-translocating P-type ATPase, flippase
( TIGR01494 ) ATPase, P-type (transporting), HAD superfamily,

Gene Expression Profile

Tetrahymena Functional Genomics Database: TTHERM_00994350

Homologs (v.2006 protein sequences)

Source Identifier Score Description

DictyBase DDB0190219 9.99709313703352e-262 JC1V2_0_01058 Q9Y2Q0 Potential
phospholipid-transporting ATP
ase IA (EC 3.6.3.1) (Chromaffi
n granule ATPase II) (ATPase c
lass I type 8A member 1).

ParameciumDB GSPATP00035083001 9.99709313703352e-262 Paramecium tetraurelia GSPATP0
0035083001 protein

ParameciumDB GSPATP00032129001 9.99709313703352e-262 Paramecium tetraurelia GSPATP0
0032129001 protein

IPI(HUMAN) IPI:IPI00032402.1 9.99709313703352e-262 1|TREMBL:Q32M35;Q59EX4|ENSEMB
L:ENSP00000342024|REFSEQ:NP_ 0
06086|VEGA:OTTHUMP00000125252;
OTTHUMP00000125253 Tax_Id=9606
Splice Isoform Long of Probab
le phospholipid-transporting A
TPase IA

TAIR AT3G27870 9.99731681937898e-180 haloacid dehalogenase-like hyd
rolase family protein

FlyBase FBgn0033837 9.99806199745668e-175

WormBase Y49E10.11b 9.99614953196877e-161 WBGene00013034 tat-1

SGD YAL026C 9.99614953196877e-161 DRS2 SGDID:S000000024, Chr I f
rom 99698-95631, reverse compl
ement, Verified ORF, "Integral
membrane Ca(2+)-ATPase involv
ed in aminophospholipid transl
ocation; required to form a sp
ecific class of secretory vesi
cles that accumulate upon acti
n cytoskeleton disruption; mut
ation affects maturation of th
e 18S rRNA"

ToxoDB 50.m03192 1.00043485889854e-105 Toxoplasma gondii ATPase 2, pu
tative

CryptoDB EAK89054 1.00009439685371e-101 Cryptosporidium parvum (Iowa)
protein EAK89054

PlasmoDB PFL0950c 7.99918061585779e-98 Plasmodium falciparum PFL0950c

Source	Identifier	Score	Description
DictyBase	DDB0190219	9.99709313703352e-262	JC1V2_0_01058 Q9Y2Q0 Potential phospholipid-transporting ATP ase IA (EC 3.6.3.1) (Chromaffi n granule ATPase II) (ATPase c lass I type 8A member 1).
ParameciumDB	GSPATP00035083001	9.99709313703352e-262	Paramecium tetraurelia GSPATP0 0035083001 protein
ParameciumDB	GSPATP00032129001	9.99709313703352e-262	Paramecium tetraurelia GSPATP0 0032129001 protein
IPI(HUMAN)	IPI:IPI00032402.1	9.99709313703352e-262	1\|TREMBL:Q32M35;Q59EX4\|ENSEMB L:ENSP00000342024\|REFSEQ:NP_ 0 06086\|VEGA:OTTHUMP00000125252; OTTHUMP00000125253 Tax_Id=9606 Splice Isoform Long of Probab le phospholipid-transporting A TPase IA
TAIR	AT3G27870	9.99731681937898e-180	haloacid dehalogenase-like hyd rolase family protein
FlyBase	FBgn0033837	9.99806199745668e-175
WormBase	Y49E10.11b	9.99614953196877e-161	WBGene00013034 tat-1
SGD	YAL026C	9.99614953196877e-161	DRS2 SGDID:S000000024, Chr I f rom 99698-95631, reverse compl ement, Verified ORF, "Integral membrane Ca(2+)-ATPase involv ed in aminophospholipid transl ocation; required to form a sp ecific class of secretory vesi cles that accumulate upon acti n cytoskeleton disruption; mut ation affects maturation of th e 18S rRNA"
ToxoDB	50.m03192	1.00043485889854e-105	Toxoplasma gondii ATPase 2, pu tative
CryptoDB	EAK89054	1.00009439685371e-101	Cryptosporidium parvum (Iowa) protein EAK89054
PlasmoDB	PFL0950c	7.99918061585779e-98	Plasmodium falciparum PFL0950c

General Information

Paragraph No Gene Name Paragraph Text
19 FLP11,
FLP18,
FLP17,
FLP8,
FLP16,
FLP15,
FLP14,
FLP6,
FLP13,
FLP10,
FLP2,
FLP1,
FLP3,
FLP9,
FLP12,
FLP4,
FLP7,
FLP5,
FLP19 The phospholipid flippase family of genes in Tetrahymena contains 20 members, FLP1-FLP20. Preliminary studies show that many of these genes are differentially regulated in response to temperature and/or the presence of a polycyclic aromatic hydrocarbon (pyrene).

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00994350(coding)
ATGTGTTTAAAGCGTAGACCTCTTGTATTTAATCATGATAGGATTATTGATGTCCAAATG
GATGATCGAGTCAAGAATAAGATTAGTCCGTTTCCCTCTAATTTTATTAAGACATCGCAT
TATACATTGATTGATTTCCTACCAATGTCTTTGCTCCTTTAATTTAAGCGCTATGCAAAT
ATTTATTTTTTGATTATAGCAATTTTATAATCAATTCCTACAATATCTCCCTTAACTCCT
CTCTCAGCCATAGCTCCTCTAGTTTTTGTGCTGGGTGTTTCGATGTTGCGTGAGGGTGTT
GAAGATTATAACAGACACAAAAGTGATACTAAAATTAATTCAGAGGAAACAACAAGAATT
TTTATTTAAGATAGTCTAGTTGAGGAAAAAATAACTTGGGCACAAGTAGAAGTAGGCGAT
ATTATCAAGGTTTATAAGGATGAACCATTCCCAGCAGATTTAATAGCAGTAGATAGTAGT
TATCCCAACGGTGTTTGCTACATAGAAACAGGAGCACTTGATGGAGAAAAAAATATGAAA
CCAAAATCGTGCCTCAGAGAAACTTATCAAATTTTTAAGGAATGCAAGTTAGAGTAAATA
CGCAGCTTAAAGTTATAAGCTGAAAAACCGAACCCTGAATTATATAAATTCAATGGGAGT
ATTGAAGGTCTATTTGAGGATGAGGTAAAATTAGAAAAAAAGGCAACAACTTAAAATAGC
AAAGTAGGAGCTCCTGTTCCTGGTCTTAAATAATAAGATAGCATGTAGAAGATTATTGAA
GAAGTTGAAAAAATAGTGGATGAGGAAAATGAGAAAAAGCAAAAATAAACAAATCCTCAA
CCATATTTGAATAGCGAGCAAGATAGTGCTCATAATACTTAACAAAATAAAAGCCAAGTA
AATTAGAAAGTAAACATTTCTACTCAAAATGGTAATCAAACCAAGAGACATCAATCATAT
TCACCTTAAAAAGTGCTTGCATCTGCTAAACAATTGCTGTTAAGAGGTGCCTTTTTGAGA
AATACAGATTATATCCTTGGAATTGTTGCTTATACAGGTTTGGACTCTAAAATTATGAGA
AACTCTGAGCCACCCAAATAAAAAACATCTGATATGGAAAAAACAATGAATACATATATT
ATAGGAATTCTCATTCTTTAGATGATTTGCTCATTTTTTACTGCTGTTCTGAATTATATT
TGGAATTCTAATAACTTAGATGGACATTGGTACTTAAAAGATGATTCTTAAATTAATCAA
TATGGAGCACTGGCTATTTTATATTTTTTTACTTATTTTCTACTATATAACACTATGATA
CCTATTTCTTTGATTGTATCTCTTGAAATGGTTAAGGTGGCATAAGGTTATTTTATTACT
AATGATAAATAAATGTACTGTGAAGAGAAAGACATTTGGCCAAAAGTTATGACAACAACA
ATCAATGAAGAACTAGGATAGGTAGAATATGTATTCTCAGATAAAACAGGAACTCTTACT
TGCAATGTAATGGAGTTTAATAAAAGTGTAATTGGTCATAATTTATATGGAGACTCAGGA
GAAAAGGACCCTAAATTACAGAAAAAAAAGTAGGATCATGAAGGCGATAAACCAAAAAAG
CATAAATTAACTTCTTTTAACTTTTACGATCGCCATTTGAATGAATTATTAGCTGAAGCT
AAACACGATTCGATAGTTAATTTACAGCTAAAGAGTGAAGATGGAAATAGTTCTTATCTA
ATTAAAACTTAGCGTGACTTAGCATGCGAATATTGGAAGCTATTAGGAACTGCTCACGAA
TGCATTATTTAAAGAGACAAGGAAACTAATGAAATAGACTATCAAGGCCCATCTCCAGAT
GAAATAACTCTTGTTGATGCAGCCAGACATATGGGATTTACCTTTGAAGGAGCCTCAAGT
GATACCATAGATATAAATGTGAGAGGTATTAAGTAAAAGGTCACATTATTGAATTCATTT
GAATTCAATAGTGATAGAAAAAGAATGTCTGTTATAATAAGAGATGGAAACGTTATTAAG
CTTTATATTAAAGGAGCAGATAGTATCATAAAATCTAGGTTGCATACAGACAAATAATAG
CCTTTCTTAGATAAAACTAATGACTATCTCACACAATTCAGTCTTATAGGGCTTCGTACC
CTTATGATGGCTATGAGGGTTTTGAGTGAAGAGGAGTATTAAGATTTCAAAAGAAAAATG
AATGCTTTGGCTGATTCAGAAAATCGTGAAAGGGAAATGGATAAATTAGCTGATTCTATA
GAGAGAAATCTTATTTTAATTGGTGCTACTGCAGTTGAGGATAAACTTTAAGATAAAGTT
CCAGAAACAATTTATGATCTTATTAAGGCCAATATTAAGGTTTGGATGCTTACTGGTGAT
AAGCTAGAAACAGCAGAAAATATTGCAAAGAGCTGCAAATTAATACAAAATGACATGAAG
ATTATTCAAATATCTGAAAAAGATGAATAATCTCTCAGAAATAATTTACTTGGAACTGCT
ATGGAAAAGTTTATTCAATTAAAAAATGATTAAGCTAAAAAATCTATGCTTGTAGAAGGA
GATTCACTGACATTAATTTTTGGAGATGTTCATTTATAAAAAGCGTTTTTGAAGATCTCT
AAAGATTGCGAATCTGTTGTTTGTTGTAGAGTTACTCCAAAATAAAAAGCACTTGTAGTT
AGATTGATAAAAGACAACTTAAAAAAAATTACACTTGCTATTGGTGATGGTGCTAATGAT
GTCAATATGATACAAGAAGCTCATATAGGATGTGGTATTTTTGGTAATGAAGGTATGCAA
GCTGCATAAAGCTCAGATTTTGCATTTGGTGAATTTAAATGTCTTTGGCGTCTAGTTTTA
GTTCATGGCAGATGGTCATACATTAGAATAGCTGAAATGATTATTTACTTCTTTTACAAA
AATATGTTATTTACAATTCCATAGCTGTACTTTTCATTTTATAATGCATTTAGCGGACAA
ACTATTTTTGATGCTTGGTTTATTTCTTTGTATAATTTGATTTTTACAGCTTTACCTTTG
ATTTCTAGAGCCGTATTTGACTAGGATGTTAATTATAAAGTTACTGTCGACTAAGTAAAA
ATGGGAGAAGAAGACAATCGTCTTTAGTCAATTTTAGAAAGAAAGGAGTAGTATTTAGAA
AAGAAATTCCCTACTTTCTACTATACAAGTTAAGATAAAACAATATTTACAGATTCAAAC
TTCTTATCTTGGGTAATTTAAGGGTTGATTCATGGTCTAATCATTTTCTATTGTACTTAT
TTGACTTTTGATTCCATTACTTTTTCAAAGGATGGTCTCTCTACAGATCTTTGGAACTTC
TCTTTAATTATATTCACATCGATCATTTTAGTGGCTGATATGAAAATTGCTATGTTTACA
AGATACTGGACTTGGATTACATACTTTACTTTTATTTTTAGTAGTTTAATACTGTACTTT
GCTTTTTTATTGGGCAGTTAATCAATCGAAACAAGTGAAGTCTGGTTGACACCTTTTTAG
ATGTTTTAAAACTCACAATTTTACTTTATATTATTTGAGACTTGTGGAATAATTTTGGCT
TTTGACATGACTGTATTTGTTTCTAGACAATTTTTAACAAAGCAGAGAATATTAGGTTAC
ATGAGATTTTTAAAATAGCCAAATGTAAATCTTGAAAAAAAGCCCACATGGGCAGAAGAC
ATGAGTCTTTTTAATTCGTTTTACAATATTTAAGACGCAAAAAATCAAAATAATGGATAA
GTTTATCTCGCAAATAGTGGTGAATCTTAACCAGAAAATGGAGACTAGATGAAAAAAATA
GACAATAAAGATCTTGTAAATCAAAACTCTTAATCGCCTATGATTAATAAGTACTAACCT
TAACACAGCAATGACAACAGATCCAAAAATAACTAAACACCTTTAAATGGTAATCCAATT
TAAATTTAAATGCAATAGTATAACATAGGCGGAGGAGTAGGTTTTGGAGACTCAAGTGCT
GATAGACTGAATTAAGAATAGCAATAGATTCAAATTTAGAATAATTAAAGACCGGCATAA
CCAAACCACGCAGGAGGTATGTAAAACACTACTCAATAATTTATGTAGACGTAAGAATTA
CTAGATTTAACCAATACTACATTATTTTAAAAAAATAGTCAATCTAATAATCAGGTGATG
GAAAATCACGCATTGAATAACTACCTTGATAAGAAACAGCCACAATAATAATAGTAATAA
TAATAATAACAATATGAAAAAAGAAATAGTTAAACAGATGTTAAATAAAATATGAATAAC
TTTGGCTATGTTGAAGAAGAAATAATTACAATATAGTCCAAAAAGAAATCTTCAAATTCT
AATGGTAATACTAATACAAATAGCAATGGTATTAAAGGAAATGGGAGAACTTCTGTTGGT
AATGTTTTGGATATAGGCAATAACCAAATTAATTAATTTGGTAATGGTGAAGAAAATGTA
ATTGCTTCAAACAAAAGTATAACCAGCCTCAATAATAGCGCACCTGGATCTAAAATTCAT
CATTTGACATTTAATTTGCAATTATAAAATCGTTCTGAGAAAGTAGAAGAGACATTCATT
TATAATGAAGTCAAAAGCAGTGCTAAAAAGTCAGATAATCTCTTACTATATTAAGACCCA
CATACACCAACACCTATAAACAATTCTATTGACAATTTAAGAGATTGA

>TTHERM_00994350(protein)
MCLKRRPLVFNHDRIIDVQMDDRVKNKISPFPSNFIKTSHYTLIDFLPMSLLLQFKRYAN
IYFLIIAILQSIPTISPLTPLSAIAPLVFVLGVSMLREGVEDYNRHKSDTKINSEETTRI
FIQDSLVEEKITWAQVEVGDIIKVYKDEPFPADLIAVDSSYPNGVCYIETGALDGEKNMK
PKSCLRETYQIFKECKLEQIRSLKLQAEKPNPELYKFNGSIEGLFEDEVKLEKKATTQNS
KVGAPVPGLKQQDSMQKIIEEVEKIVDEENEKKQKQTNPQPYLNSEQDSAHNTQQNKSQV
NQKVNISTQNGNQTKRHQSYSPQKVLASAKQLLLRGAFLRNTDYILGIVAYTGLDSKIMR
NSEPPKQKTSDMEKTMNTYIIGILILQMICSFFTAVLNYIWNSNNLDGHWYLKDDSQINQ
YGALAILYFFTYFLLYNTMIPISLIVSLEMVKVAQGYFITNDKQMYCEEKDIWPKVMTTT
INEELGQVEYVFSDKTGTLTCNVMEFNKSVIGHNLYGDSGEKDPKLQKKKQDHEGDKPKK
HKLTSFNFYDRHLNELLAEAKHDSIVNLQLKSEDGNSSYLIKTQRDLACEYWKLLGTAHE
CIIQRDKETNEIDYQGPSPDEITLVDAARHMGFTFEGASSDTIDINVRGIKQKVTLLNSF
EFNSDRKRMSVIIRDGNVIKLYIKGADSIIKSRLHTDKQQPFLDKTNDYLTQFSLIGLRT
LMMAMRVLSEEEYQDFKRKMNALADSENREREMDKLADSIERNLILIGATAVEDKLQDKV
PETIYDLIKANIKVWMLTGDKLETAENIAKSCKLIQNDMKIIQISEKDEQSLRNNLLGTA
MEKFIQLKNDQAKKSMLVEGDSLTLIFGDVHLQKAFLKISKDCESVVCCRVTPKQKALVV
RLIKDNLKKITLAIGDGANDVNMIQEAHIGCGIFGNEGMQAAQSSDFAFGEFKCLWRLVL
VHGRWSYIRIAEMIIYFFYKNMLFTIPQLYFSFYNAFSGQTIFDAWFISLYNLIFTALPL
ISRAVFDQDVNYKVTVDQVKMGEEDNRLQSILERKEQYLEKKFPTFYYTSQDKTIFTDSN
FLSWVIQGLIHGLIIFYCTYLTFDSITFSKDGLSTDLWNFSLIIFTSIILVADMKIAMFT
RYWTWITYFTFIFSSLILYFAFLLGSQSIETSEVWLTPFQMFQNSQFYFILFETCGIILA
FDMTVFVSRQFLTKQRILGYMRFLKQPNVNLEKKPTWAEDMSLFNSFYNIQDAKNQNNGQ
VYLANSGESQPENGDQMKKIDNKDLVNQNSQSPMINKYQPQHSNDNRSKNNQTPLNGNPI
QIQMQQYNIGGGVGFGDSSADRLNQEQQQIQIQNNQRPAQPNHAGGMQNTTQQFMQTQEL
LDLTNTTLFQKNSQSNNQVMENHALNNYLDKKQPQQQQQQQQQQYEKRNSQTDVKQNMNN
FGYVEEEIITIQSKKKSSNSNGNTNTNSNGIKGNGRTSVGNVLDIGNNQINQFGNGEENV
IASNKSITSLNNSAPGSKIHHLTFNLQLQNRSEKVEETFIYNEVKSSAKKSDNLLLYQDP
HTPTPINNSIDNLRD

>TTHERM_00994350(gene)
GCTATCGTCGAATCTAAGCTAAAATTAGGAGCTAAAAAATATTATTATGTGTTTAAAGCG
TAGACCTCTTGTATTTAATCATGATAGGATTATTGATGTCCAAATGGATGATCGAGTCAA
GAATAAGATTAGTCCGTTTCCCTCTAATTTTATTAAGACATCGCATTATACATTGATTGA
TTTCCTACCAATGTCTTTGCTCCTTTAATTTAAGCGCTATGCAAATATTTATTTTTTGAT
TATAGCAATTTTATAATCAATTCCTACAATATCTCCCTTAACTCCTCTCTCAGCCATAGC
TCCTCTAGTTTTTGTGCTGGGTGTTTCGATGTTGCGTGAGGGTGTTGAAGATTATAACAG
ACACAAAAGTGATACTAAAATTAATTCAGAGGAAACAACAAGAATTTTTATTTAAGATAG
TCTAGTTGAGGAAAAAATAACTTGGGCACAAGTAGAAGTAGGCGATATTATCAAGGTTTA
TAAGGATGAACCATTCCCAGCAGATTTAATAGCAGTAGATAGTAGTTATCCCAACGGTGT
TTGCTACATAGAAACAGGAGCACTTGATGGAGAAAAAAATATGAAACCAAAATCGTGCCT
CAGAGAAACTTATCAAATTTTTAAGGAATGCAAGTTAGAGTAAATACGCAGCTTAAAGTT
ATAAGCTGAAAAACCGAACCCTGAATTATATAAATTCAATGGGAGTATTGAAGGTCTATT
TGAGGTAATCATTTAAAAAAACTCATGGCAATTACTTTTACTTCAATTTAAAGTTTTAAA
TATATAAAATTGTTTGTTGAATCATGCAATATAAAAAGCTAATATATAACAAAGTGTTAT
TTAAGCAAAGTATTCATTTAGCAGGTGTTTCGAATTATGTATTTAAATATAGGTTTAAAA
TATATTATCAAGCCGAATAAACTTTTTGACTTCAAGTAGGAATTAGGTATTAAATGAGAA
TGAGATAAAAAATTTAAAGTTGTTATTAATACTTTATTAATATTTAATTTACTAATAGTG
AGTGATACTAGTATAATAAATTGATAACAAAAAACTAAGCCCTTAAACGAATAAACAAAA
TTTTTAAAAAACTCTACTTCATTTAGTTTTATAAAGATTCTTTTGAAGAGATAATCATAA
TTATTACAAAAAAGTTGATGAATATATAATACAATTTGTAAAACAAAAATAAATACCCAA
TCAATCAATCAATTCTCTTCTTTTAATTTTCTCACAAAACTAATTTATTTTTATCTAGAA
CTTAAAAAAAAACCTAACTAGAGATTGATAAGAAACCAATAAATTAAAAAAGCATTTTTT
ATTCAGTATTTTTTGAATACCAAGCAAAAACATTTGATTGAAACCAGATTAAAATTAATT
AATCGAAATTAGATCCAATTTGATAGATTTTTTATCTATTTTGTGGTTGCAAAACAAATA
CTTCTCAAACAATTTTTTTTCTTATTCATTAATAATAATTGGAAGTAAACTAGTTCAGAT
TACATTTTTGACATTTTATTGAAATACATTCAAACAAAAAAATAAATAAGTGCAAATATT
TTTAACATTATATTTAAATAAGAACAAATAATTTTCTTTGCTTTTATAATAAAGGAAAAT
AAAATTGATAATTTCATCATTTCTAGCTTATTAGCCATGAATTATTTTTTTTTCAAACTA
TCAAAAATAACTAAAAATGAATTAAAAATGTATTTTTTTAAAAATTAGGATGAGGTAAAA
TTAGAAAAAAAGGCAACAACTTAAAATAGCAAAGTAGGAGCTCCTGTTCCTGGTCTTAAA
TAATAAGATAGCATGTAGAAGATTATTGAAGAAGTTGAAAAAATAGTGGATGAGGAAAAT
GAGAAAAAGCAAAAATAAACAAATCCTCAACCATATTTGAATAGCGAGCAAGATAGTGCT
CATAATACTTAACAAAATAAAAGCCAAGTAAATTAGAAAGTAAACATTTCTACTCAAAAT
GGTAATCAAACCAAGAGACATCAATCATATTCACCTTAAAAAGTGCTTGCATCTGCTAAA
CAATTGCTGTTAAGAGGTGCCTTTTTGAGAAATACAGATTATATCCTTGGAATTGTTGCT
TATACAGGTTTGGACTCTAAAATTATGAGAAACTCTGAGCCACCCAAATAAAAAACATCT
GATATGGAAAAAACAATGAATACATATATTATAGGTAACTTTTTTGTAATTTATCATGAT
TCAATTTATTGATTTCGAGATCTCTACTTTAGTAGTTTAACTAAATAATTAAATACCTAT
TTTTAAAAGAAAATAAAATAAGCTTTAGTGAAAAAAAACATTTATGGTATCTTTTATTTA
GATTATATTGAAGGGTTACTATTAATTTTTTTTGGCTAATAAATTCTTTTCATATATTTG
AATAATTTCGAATTTTGTAAATACTTAAAATAGATAAAAAATGAAACCCTTTAATTATAT
ATCATAAACAATAAATAGAATGAATGATAAATCTAATAAACAATAAAATTAGAATGATAA
ATATAAGAAAAATTAAAATTAGAAAACCTTTTCTATTCTAATTGGAGATCAAATAAAATT
TATTAAAAACTAAGTTATAGCCCAATATTACTCTTACTTTTTATATAAAAATTGTCAATA
AATTACTTGATTTCTAGTTATTTTAAACCAAAGTTACTAAAATTGAAATTATTTTTATCA
CTTTAAAATTGTTTCATCATTTCTGCTTTCAAGGCATGCTTTGGAATTTTAAAAAGGTTG
AGAAGACTTAATAATTGAAATTAAATTTTATTTTCTTTAAATAATTTTCCAATTAAATTT
AGACTATCATGTTTAATTTTTAAGACAAAATCCTTTAAAAAATGTTTTAAATTATTTTTT
TAAATAATAAATAATAGGAATTCTCATTCTTTAGATGATTTGCTCATTTTTTACTGCTGT
TCTGAATTATATTTGGAATTCTAATAACTTAGATGGACATTGGTACTTAAAAGATGATTC
TTAAATTAATCAATATGGAGCACTGGCTATTTTATATTTTTTTACTTATTTTCTACTATA
TAACACTATGATACCTATTTCTTTGATTGTATCTCTTGAAATGGTTAAGGTGGCATAAGG
TTATTTTATTACTAATGATAAATAAATGTACTGTGAAGAGAAAGACATTTGGCCAAAAGT
TATGACAACAACAATCAATGAAGAACTAGGATAGGTAGAATATGTATTCTCAGATAAAAC
AGGAACTCTTACTTGCAATGTAATGGAGTTTAATAAAAGTGTAATTGGTCATAATTTATA
TGGAGACTCAGGAGAAAAGGACCCTAAATTACAGAAAAAAAAGTAGGATCATGAAGGCGA
TAAACCAAAAAAGCATAAATTAACTTCTTTTAACTTTTACGATCGCCATTTGAATGAATT
ATTAGCTGAAGCTAAACACGATTCGATAGTTAATTTACAGCTAAAGAGTGAAGATGGAAA
TAGTTCTTATCTAATTAAAACTTAGCGTGACTTAGCATGCGAATATTGGAAGCTATTAGG
AACTGCTCACGAATGCATTATTTAAAGAGACAAGGAAACTAATGAAATAGACTATCAAGG
CCCATCTCCAGATGAAATAACTCTTGTTGATGCAGCCAGACATATGGGATTTACCTTTGA
AGGAGCCTCAAGTGATACCATAGATATAAATGTGAGAGGTATTAAGTAAAAGGTCACATT
ATTGAATTCATTTGAATTCAATAGTGATAGAAAAAGAATGTCTGTTATAATAAGAGATGG
AAACGTTATTAAGCTTTATATTAAAGGAGCAGATAGTATCATAAAATCTAGGTTGCATAC
AGACAAATAATAGCCTTTCTTAGATAAAACTAATGACTATCTCACACAATTCAGTCTTAT
AGGGCTTCGTACCCTTATGATGGCTATGAGGGTTTTGAGTGAAGAGGAGTATTAAGATTT
CAAAAGAAAAATGAATGCTTTGGCTGATTCAGAAAATCGTGAAAGGGAAATGGGTATAAA
TTATTTCATTTAATTCAATTAGAAACATTTCAAAAAAATAAAACGAACTTCAAAAATACT
AATAAAATATTAAAATATATTTTAGATATTCAATTTTAGTATTTAAATATTTTTATTAAA
AATTTTATTAGATAAATTAGCTGATTCTATAGAGAGAAATCTTATTTTAATTGGTGCTAC
TGCAGTTGAGGATAAACTTTAAGATAAAGTTCCAGAAACAATTTATGATCTTATTAAGGC
CAGTAATAAAATTTCAACAAATAATATATCATTAAATAAAATATATTTTTTTAAGATATT
AAGGTTTGGATGCTTACTGGTGATAAGCTAGAAACAGCAGAAAATATTGCAAAGAGCTGC
AAATTAATACAAAATGACATGAAGATTATTCAAATATCTGAAAAAGATGAATAATCTCTC
AGAAATAATTTACTTGGAACTGCTATGGAAAAGTTTATTCAATTAAAAAATGATTAAGCT
AAAAAATCTATGCTTGTAGAAGGAGATTCACTGACATTAATTTTTGGAGATGTTCATTTA
TAAAAAGCGTTTTTGAAGATCTCTAAAGATTGCGAATCTGTTGTTTGTTGTAGAGTTACT
CCAAAATAAAAAGCACTTGTAGTTAGATTGATAAAAGACAACTTAAAAAAAATTACACTT
GCTATTGGTGATGGTGCTAATGATGTCAATATGATACAAGAAGCTCATATAGGTAAAATA
ATTCAAATAAATTATAATTGAAATAAAAATTAAAGCAATGATCAATAAGCAATATTTATT
AATTAATTTCAAATAATCATTAAATTAGGATGTGGTATTTTTGGTAATGAAGGTATGCAA
GCTGCATAAAGCTCAGATTTTGCATTTGGTGAATTTAAATGTCTTTGGCGTCTAGTTTTA
GTTCATGGCAGATGGTCATACATTAGAATAGCTGAAATGATTATTTACTTCTTTTACAAA
AATATGTAATTTTTTAACAAAAATAAATAAAGAATCAATTGAAGAATTCAATTATAATTT
ATATTATTATAATACTAGGTTATTTACAATTCCATAGCTGTACTTTTCATTTTATAATGC
ATTTAGCGGACAAACTATTTTTGATGCTTGGTTTATTTCTTTGTATAATTTGATTTTTAC
AGCTTTACCTTTGATTTCTAGAGCCGTATTTGACTAGGATGTTAATTATAAAGTTACTGT
CGACTAAGTAAAAATGGGAGAAGAAGACAATCGTCTTTAGTCAATTTTAGAAAGAAAGGA
GTAGTATTTAGAAAAGAAATTCCCTACTTTCTACTATACAAGTTAAGATAAAACAATATT
TACAGATTCAAACTTCTTATCTTGGGTAATTTAAGGGTTGATTCATGGTCTAATCATTTT
CTATTGTACTTATTTGACTTTTGATTCCATTACTTTTTCAAAGGATGGTCTCTCTACAGA
TCTTTGGAACTTCTCTTTAATTATATTCACATCGATCATTTTAGTAAAATCTTAATTAAC
ATTTCATATTTTGTTTCTTATTGCAACTTTTCATAATTTATAGACAATTTAAAAATAAAA
TAAAGCAAAATTTTATATTTTACATGAAATTTTTATATCAAGATTTTTTAATTGTTTAAA
AAAAAATAATTTTTACAATTTTAAGGTTGTTATTAAAATAATAAATATTAAAAATAAAAA
GGTGGCTGATATGAAAATTGCTATGTTTACAAGATACTGGACTTGGATTACATACTTTAC
TTTTATTTTTAGTAGTTTAATACTGTACTTTGCTTTTTTATTGGGCAGTTAATCAATCGA
AACAAGTGAAGTCTGGTTGACACCTTTTTAGATGTTTTAAAACTCACAATTTTACTTTAT
ATTATTTGAGACTTGTGGAATAATTTTGGCTTTTGACATGACTGTATTTGTTTCTAGACA
ATTTTTAACAAAGCAGAGAATATTAGGTTACATGAGATTTTTAAAATAGCCAAATGTAAA
TCTTGAAAAAAAGCCCACATGGGCAGAAGACATGAGTCTTTTTAATTCGTTTTACAATAT
TTAAGACGCAAAAAATCAAAATAATGGATAAGTTTATCTCGCAAATAGTGGTGAATCTTA
ACCAGAAAATGGAGACTAGATGAAAAAAATAGACAATAAAGATCTTGTAAATCAAAACTC
TTAATCGCCTATGATTAATAAGTACTAACCTTAACACAGCAATGACAACAGATCCAAAAA
TAACTAAACACCTTTAAATGGTAATCCAATTTAAATTTAAATGCAATAGTATAACATAGG
CGGAGGAGTAGGTTTTGGAGACTCAAGTGCTGATAGACTGAATTAAGAATAGCAATAGAT
TCAAATTTAGAATAATTAAAGACCGGCATAACCAAACCACGCAGGAGGTATGTAAAACAC
TACTCAATAATTTATGTAGACGTAAGAATTACTAGATTTAACCAATACTACATTATTTTA
AAAAAATAGTCAATCTAATAATCAGGTGATGGAAAATCACGCATTGAATAACTACCTTGA
TAAGAAACAGCCACAATAATAATAGTAATAATAATAATAACAATATGAAAAAAGAAATAG
TTAAACAGATGTTAAATAAAATATGAATAACTTTGGCTATGTTGAAGAAGAAATAATTAC
AATATAGTCCAAAAAGAAATCTTCAAATTCTAATGGTAATACTAATACAAATAGCAATGG
TATTAAAGGAAATGGGAGAACTTCTGTTGGTAATGTTTTGGATATAGGCAATAACCAAAT
TAATTAATTTGGTAATGGTGAAGAAAATGTAATTGCTTCAAACAAAAGTATAACCAGCCT
CAATAATAGCGCACCTGGATCTAAAATTCATCATTTGACATTTAATTTGCAATTATAAAA
TCGTTCTGAGAAAGTAGAAGAGACATTCATTTATAATGAAGTCAAAAGCAGTGCTAAAAA
GTCAGATAATCTCTTACTATATTAAGACCCACATACACCAACACCTATAAACAATTCTAT
TGACAATTTAAGAGATTGA

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Paragraph No	Gene Name	Paragraph Text
19	FLP11, FLP18, FLP17, FLP8, FLP16, FLP15, FLP14, FLP6, FLP13, FLP10, FLP2, FLP1, FLP3, FLP9, FLP12, FLP4, FLP7, FLP5, FLP19	The phospholipid flippase family of genes in Tetrahymena contains 20 members, FLP1-FLP20. Preliminary studies show that many of these genes are differentially regulated in response to temperature and/or the presence of a polycyclic aromatic hydrocarbon (pyrene).