Identifiers and Description

Gene Model Identifier

TTHERM_00136510

Standard Name

FIM1 (FIMbrin 1)

Aliases

PreTt24376 | 10.m00425 | 3698.m00144

Description

Fimbrin-like 71 K protein; actin filament bundling protein; contains 2 alpha-actinin-type binding domains, but lacks E

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• oral apparatus (IDA) | GO:0031912 | Ref:14607987
• cleavage furrow (IDA) | GO:0032154 | Ref:14607987

Molecular Function

• actin filament binding (IDA) | GO:0051015 | Ref:14607987

Biological Process

• actin filament bundle assembly (IPI) | GO:0051017 | Ref:14607987

Domains

• ( PF00307 ) Calponin homology (CH) domain

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.8%

TetraMine Data

TTHERM_00136510

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_05818.1	9.997093137033517e-262	fimbrin-like 71 K protein (523 aa)
Oxytricha	Contig10286.0.1.g44	1.999872053281847e-142	Calponin homology (CH) domain
SGD	YDR129C	2.0000211193600847e-137	SAC6 Fimbrin, actin-bundling p rotein; cooperates with Scp1p (calponin/transgelin) in the o rganization and maintenance of the actin cytoskeleton
DictyBase	DDB_G0277855	3.0001046824819247e-131	fimA on chromosome: 3 position 187950 to 189871
Stentor Coeruleus	SteCoe_4363	2.001470128041443e-75
WormBase	WBGene00022425	5.9981191891941984e-64	locus:plst-1 status:Partiall y_confirmed UniProt:U4PBU8 protein_id:CDH93209.1

General Information

No Data fetched for General Information

Associated Literature

1. Ref:14607987: Shirayama S, Numata O (2003) Tetrahymena fimbrin localized in the division furrow bundles actin filaments in a calcium-independent manner. Journal of biochemistry 134(4):591-8
2. Ref:11942614: Numata O, Gonda K (2001) Determination of division plane and organization of contractile ring in Tetrahymena. Cell structure and function 26(6):593-601
3. Ref:10731670: Watanabe A, Yonemura I, Gonda K, Numata O (2000) Cloning and sequencing of the gene for a Tetrahymena fimbrin-like protein. Journal of biochemistry 127(1):85-94
4. Ref:10816251: Numata O, Gonda K, Watanabe A, Kurasawa Y (2000) Cytokinesis in Tetrahymena: determination of division plane and organization of contractile ring. Microscopy research and technique 49(2):127-35
5. Ref:9538250: Watanabe A, Kurasawa Y, Watanabe Y, Numata O (1998) A new Tetrahymena actin-binding protein is localized in the division furrow. Journal of biochemistry 123(4):607-13

Sequences

>TTHERM_00136510(coding)
ATGGATACCTTAAAGACTGCTGTAAAGACTAATGTCGAAGCTAAATAAAGCGACACAAAT
GCTATTCACTCATTTACTTAAGATGAAGTTAATGCTTACTGCGAACATATTAACTACTAT
CTTTCTGATGATGCTGACCTCAAAGAATTATTGCCAATTGATCCTTAAAGCAATAAGATT
TTTGAAGCTGTTGGAGATGGTGTCTTGCTTTGCAAATTAATCAACAAAGCCACTCCTGGT
ACTATTGACCCTAGAGCCATCAACACCAAGAACCTTAACATCTTTAAGAAAAATGAAAAC
TTAACCTTAGCTATAGCTTCTGCTAGAGCAATTGGCTGTGTTTGCGTTAATATTACAAAC
AATAGCATTATAGATAAGAGAGAACATATTATTTTGGGTCTTGTTTGGTAGATTATCAAG
GCTTAAATGTTGTTTAAGATTGACTTGAAAAACCACCCTTATTTGATTAGACTTAAAAAG
GAAGAAGAAGAAATTAGTGATCTTCTTAAACTCCCTAAAGAAGAACTTTTGATCCGTTGG
TTCAATTACCATTTAGAAAATGCTAAGCACTCAACTAAGATTAATAACTTTTCTAAGGAT
GTTTCCTCAGGTACTGAATACACAGTTTTACTCAACCAAATTGCTCCTGAAAAGTGCAAC
AAAGACGGATTAAATTTAGAACACCTTGAAAGATGCAAGAAGGTTATTAATGATTCTAAA
CTTTTGGGAGTACCTCCTTGTATTAAGCCTTCTGATATTGTAAATGGAAATCAAAAGCTT
AACTTGATTTTCTGTGCTCACTTATTCAACAATTGCCCTGGTTTAACTCCTACTGAACAA
GAAAAAATTGATGCTGCTGGCATGATAGATGATGATAACGATCCTGAAGCTTCTCGTGAA
GAAAGAGTTTTCAGAATGTGGATGAACTCTTTAAATATTGAAGATGTTTATCTTAACAAT
ATGATTCAAGATTTAAGAGATGGTATCGTTTTATGTAAGATTATGGATAAATTAGCTCCA
GGAAAAGTTGACTTGAAGAAGGTTTCAAATAAAAACTCTAAATTCACTAAAATACAAAAC
GCTAACTACGCAGTATAATTAGCTAAGGATTTACATTTATAAATTGTTGGTATTGGTGGT
ACTGATATTGTAGATGGTAACAAAAAGCTTATCCTTGCTATTGTTTGGTAACTCATGAGA
AAGTAATCATTACAGGTTATTGGTGAATTGAATGAACAAAAATTAGTAGAATGGGGTAAT
AGTAGAATTCCTCAAGATAAACATATAACTGGATTTAAAGATAAATCTCTTAAAAACTCA
CATTTCTTCTTCAAGATTATGGAATCTATTGAACCTAGAGCTATCAATTAGGATTTGATA
ACTCCTGGTGAGACTGATGAAGAAGTCACTAACAATGCTAAATACGCTATCTCTGTTGCT
CGTAAGCTTGGTGCAGCAGTTTTCCTTGTTTGGGAACACATTAGAGACGTCAATCCTAAA
TTTTTAATGACATTTACTGCTTCTCTCTACCACTGTGCTAAAGAATACGAAGGAAAGAAG
GTCTAATGA

>TTHERM_00136510(protein)
MDTLKTAVKTNVEAKQSDTNAIHSFTQDEVNAYCEHINYYLSDDADLKELLPIDPQSNKI
FEAVGDGVLLCKLINKATPGTIDPRAINTKNLNIFKKNENLTLAIASARAIGCVCVNITN
NSIIDKREHIILGLVWQIIKAQMLFKIDLKNHPYLIRLKKEEEEISDLLKLPKEELLIRW
FNYHLENAKHSTKINNFSKDVSSGTEYTVLLNQIAPEKCNKDGLNLEHLERCKKVINDSK
LLGVPPCIKPSDIVNGNQKLNLIFCAHLFNNCPGLTPTEQEKIDAAGMIDDDNDPEASRE
ERVFRMWMNSLNIEDVYLNNMIQDLRDGIVLCKIMDKLAPGKVDLKKVSNKNSKFTKIQN
ANYAVQLAKDLHLQIVGIGGTDIVDGNKKLILAIVWQLMRKQSLQVIGELNEQKLVEWGN
SRIPQDKHITGFKDKSLKNSHFFFKIMESIEPRAINQDLITPGETDEEVTNNAKYAISVA
RKLGAAVFLVWEHIRDVNPKFLMTFTASLYHCAKEYEGKKVQ

>TTHERM_00136510(gene)
ATGGATACCTTAAAGACTGCTGTAAAGACTAATGTCGAAGCTAAATAAAGCGACACAAAT
GCTATTCACTCATTTACTTAAGATGAAGTTAATGCTTACTGCGAACATATTAACTACTAT
CTTTCTGTAATATTATTTTTATATTTTCAAAAGTTTATTCAGTTTTATCAAAAAACTTTA
GGATGATGCTGACCTCAAAGAATTATTGCCAATTGATCCTTAAAGCAATAAGATTTTTGA
AGCTGTTGGAGATGGTGTCTTGCTTTGGTAATTTCACGATTTTTCAAAAATTTGTTATAG
AATTTTATTTTGTTAATTCTATTTAGCAAATTAATCAACAAAGCCACTCCTGGTACTATT
GACCCTAGAGCCATCAACACCAAGAACCTTAACATCTTTAAGAAAAATGTAAACATATTA
AATATTTTGATTGCAAGAAAATTATTTAAAAAATAATCTCAATCAGTCAATAAAAGGAGA
ATTTTAATTCATTCCATTAAATTTATTTTCTTAAAATAGGAAAACTTAACCTTAGCTATA
GCTTCTGCTAGAGCAATTGGCTGTGTTTGCGTTAATATTACAAACAATAGCATTATAGAT
AAGAGAGAACATATTATTTTGGGTCTTGTTTGGTAGATTATCAAGGTATTTATTTTATTT
TTGGATTTTTTTTTCTTAAATGTTTGTTTGTTTATTAAATATGTGAATATTTCAGACCTT
CAATATGTTTTTTATAATAAAAAGGCTTAAATGTTGTTTAAGATTGACTTGAAAAACCAC
CCTTATTTGATTAGACTTAAAAAGGAAGAAGAAGAAATTAGTGATCTTCTTAAACTCCCT
AAAGAAGAACTTTTGATCCGTTGGTTCAATTACCATTTAGAAAATGCTAAGCACTCAACT
AAGATTAATAACTTTTCTAAGGATGTTTCCTCAGGTATTTGAAATGAGCTTATTGAATAT
TAATTAAGGCATTTATATATCCGAAAAAAAATTTTTTATAAATAGAATAAGAAAAATAAT
TAATTTTATTTTTAAATTAAATTAGGTACTGAATACACAGTTTTACTCAACCAAATTGCT
CCTGAAAAGTGCAACAAAGACGGATTAAATTTAGAACACCTTGAAAGATGCAAGAAGGTT
ATTAATGATTCTAAACTTTTGGGAGTACCTCCTTGTATTAAGCCTTCTGATATTGTAAAT
GGAAATCAAAAGCTTAACTTGATTTTCTGTGCTCACTTATTCAACAATTGCCCTGGTTTA
ACTCCTACTGAACAAGAAAAAATTGATGCTGCTGGCATGATAGATGATGATAACGATCCT
GAAGCTTCTCGTGAAGAAAGAGGTAAATAAGAAATTTATTAAAAATTCAGATTAAATTCT
TATTTTAACTCGCATACACTGAGCATTTGAATTTAAGTTTAATTTCTGAAAAAAGATTTT
ATATATCTTATACAAATATTTAGCCCATATTATCAATATCAGTTTAGTTTTTAAAGAAAA
GTAATTAACTAAATCAAAGATATTATTTAAGATTACTGGATAGGAAAAGATTGCTATGTA
ATTAATGGAAAAATAAGCTATCTTAATAAAATTTATCTCTATATCTTTATACCGATCAGT
CAAATAATTAAATGTTAATTTCACTGAGAAAAAAACTTTTTTGAAGAATAAAAATAATTA
ACTTTTTTGGATTCATTTAAAATGAAATTAATGGTTTTAAATTTCAATAATTTATCAGTA
AAAATTTGAAAAAGTTAATTTTATCCTAAAATTTTATTCTTTTTATATCAAATTTCTATT
TTAAGGTATGGTATTATATCATTTTTAATAAAAAATCTATCTATACATAGTTTTCAGAAT
GTGGATGAACTCTTTAAATATTGAAGATGTTTATCTTAACAATATGATTCAAGATTTAAG
AGATGGTATCGTTTTATGTAAGATTATGGATAAATTAGCTCCAGGAAAAGTTGACTTGAA
GAAGGTTTCAAATAAAGTAAAAAATTGAATGAATTTTCTAAAAGTTTATTTTAAATTTAA
TTAATTTATTTCTTTATTAAATTAAAAATAGAACTCTAAATTCACTAAAATACAAAACGC
TAACTACGCAGTATAATTAGCTAAGGATTTACATTTATAAATTGTTGGTATTGGTGGTAC
TGATATTGTAGATGGTAACAAAAAGCTTATCCTTGCTATTGTTTGGTAACTCATGAGAAA
GTAATCATTACAGGTAATAAACAATAAGCAAATTTTAATACAAAAAATCTATCAAAAATT
ATATCTGATAGCTTATTCATTCATTAATATTATAAATAGTAGTTAAAGGCGTTTTGAATT
TTAATTTAATAATAGGTTATTGGTGAATTGAATGAACAAAAATTAGTAGAATGGGGTAAT
AGTAGAATTCCTCAAGATAAACATATAACTGGATTTAAAGATAAATCTCTTAAAAACTCA
CATTTCTTCTTCAAGATTATGGAATCTATTGAACCTAGAGCTATCAATTAGGATTTGATA
ACTCCTGGTGAGACTGATGAAGAAGTCACTAACAATGCTAAATACGCTATCTCTGTTGCT
CGTAAGCTTGGTGCAGCAGTTTTCCTTGTTTGGGAACACATTAGAGACGTAAAATTAAAA
ATCAAATCTTATTATTATATAATAAATTATAATTCATTTTATAAAATAGGTCAATCCTAA
ATTTTTAATGACATTTACTGCTTCTCTCTACCACTGTGCTAAAGAATACGAAGGAAAGAA
GGTCTAATGA